10 Best South America Multiday Tours in October 2025

Accommodations

BudgetSimple stays with essential amenities. Typically guesthouses, hostels or hotels rated below 3 stars — clean, no-frills, and great for value-conscious travelers.
Mid-rangeComfortable and reliable 3-star stays. Expect private rooms, en-suite bathrooms, and solid amenities — a great balance between comfort and cost.
PremiumUpscale 4-5 star hotels and lodges. Enjoy high-end service, refined comfort, and premium locations — ideal for travelers seeking extra indulgence.

13% OFF TODAY

Super Sales

Central American Journey - October 2025

No booking fees

Best price guaranteed

Tropical cloud forests alive with jungle melodies and native wildlife, vast freshwater lakes and active volcanoes, historic cities and shared moments with locals – this pocket of Central America is a slice of paradise. On this 16-day Central American journey, take in all the must-visit spots like Guatemala, Honduras, El Salvador, Nicaragua and Costa Rica. You’ll spot colourful birds and see how indigo dying works in Suchitoto, explore the World Heritage-listed ruins of Copan, stand in the shadow of mighty Arenal Volcano and spot sloths among the canopy of Monteverde. This adventure is perfect for those who like to experience a destination 'la forma natural' (the natural way).

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Hut

Age Range

15-99 yrs

Operated in

english

Destinations

San Jose, Antigua, Granada, La F

San Jose, Antigua, Granada, La Fortuna, Leon, Monteverde Cloud Forest Biological Preserve, Arenal Volcano, Ometepe Island, Copan, Suchitoto, El Cuco, Granada

13% OFF TODAY

Duration16 days

From

USD 2,335

USD 2,039

Saving

USD 296

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Exploring South America -13 days - October 2025

4.9

(5 reviews )

Trip customizable

Best price guaranteed

We planned our epic trip to South America with Analia. She was excellent at listening, advising, tailoring, meeting expectations for our requirements to make this trip an amazing experience. Joaquina then took over to support and guide us through the finer details of the trip, and whilst we were on our holiday. We had access to a WhatsApp support for any queries along the way, a 24 hour emergency WhatsApp number also. The tours and guides were of all very good, with some guides standing out as excellent. We did find it a little annoying when on larger tours with multi lingual guides as we seemed to be in the minority. It felt like we weren't gaining from the same level of information as that delivered to the Spanish speaking! However, overall, the service was seamless, caring, friendly and professional. I would recommend the team without hesitation. Thank you 🙂🙂

Cultural, religious and historic sites

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Cusco, Machu Picch

Buenos Aires, Cusco, Machu Picchu, Rio de Janeiro, Sacred Valley, Chinchero District, Aguas Calientes, Iguazu Falls

Duration13 days

From

USD 3,895

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Highlights Of Chile & Argentina - October 2025

22% OFF TODAY

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Highlights of Chile & Argentina - October 2025

(4 reviews )

No booking fees

Best price guaranteed

Great experience, great countries, wonderful group, wonderful activities. Thanks you so much

Active and outdoor

Tour Type

Small Group Tour

Accommodation

Resort, Hotel

Age Range

12-100 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Pucon, San Carlos de Bariloche

22% OFF TODAY

Duration10 days

From

USD 2,999

USD 2,327

Saving

USD 672

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Best Of Argentina, Uruguay & Brazil - October 2025

18% OFF TODAY

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Best of Argentina, Uruguay & Brazil - October 2025

No booking fees

Best price guaranteed

Hug the eastern coastline of South America on a ten-day adventure. This down-to-earth adventure takes you from Buenos Aires to Rio de Janeiro via Colonia del Sacramento, an estancia and the spectacular Iguazu Falls. Embrace ranch life during your estancia stay and explore the grounds on horseback, wonder at the largest waterfall in the world and get a taste of Rio’s nightlife.

City sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Co

Buenos Aires, Rio de Janeiro, Colonia Del Sacramento, Tacuarembo, Foz Do Iguazu, Iguazu Falls

18% OFF TODAY

Duration10 days

From

USD 2,930

USD 2,415

Saving

USD 515

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18% OFF TODAY

Super Sales

Best of Brazil - October 2025

(2 reviews )

No booking fees

Best price guaranteed

Sun, sand and plenty of samba – see some of Brazil’s hottest highlights all packed together in an eight-day adventure. Start the party in Rio de Janeiro, where Copacabana, Ipanema and Christ the Redeemer all vie for your attention. Travel to the cobbled streets of Paraty, then cruise to the pristine Ilha Grande – an island where lush green rainforests meet untouched sandy beaches. You’ll have local knowledge to guide your way and plenty of time to explore at your own pace, and when it comes to free time in Brazil, all you need to know is the word ‘praia’ – beach.

City sightseeingBeach

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Rio de Janeiro, Paraty, Ilha Grande

18% OFF TODAY

Duration8 days

From

USD 1,020

USD 841

Saving

USD 179

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Super Sales

Best of South America - October 2025

No booking fees

Best price guaranteed

Take a deep dive into Peru, Bolivia, Argentina, Uruguay and Brazil on an epic 51-day trip. With local leaders guiding you to the best neighbourhoods as well as plenty of time to explore independently, you’ll wonder what took you so long to appreciate this corner of the globe. Trek or train to the lost Inca citadel of Machu Picchu, spend a few days on an estancia in Uruguay, take a 4WD adventure through the Andean desert to the Uyuni salt flats and wind up in all the best cities – Buenos Aires, La Paz and Lima, to name a few. Finish up with beach and party vibes in Brazil – a perfect spot to chill out after your adventure to South America’s hotspots.

City sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel, Camping, Home-stay

Age Range

15-99 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Cusco, Inc

Rio de Janeiro, Lima, Cusco, Inca Trail, Machu Picchu, Lake Titicaca, Puno, La Paz, Sucre, Potosi, Uyuni, Salar De Uyuni, Ballestas Islands and Paracas National Reserve, Tilcara, Buenos Aires, Colonia Del Sacramento, Estancia, Iguazu Falls, Iguazu Falls, Nazca, Paraty, Ilha Grande, Arequipa, Colca Canyon

Duration51 days

From

USD 9,115

USD 8,842

Saving

USD 273

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13% OFF TODAY

Super Sales

Central America Explorer - October 2025

No booking fees

Best price guaranteed

Dive into Central America on this 48-day adventure, bookended by two chaotic capitals and filled with fun, adventure and culture. Journey through Mexico, Belize, Guatemala, Honduras, El Salvador, Nicaragua and Costa Rica on an adventure through the tantalising highlights of the region. Get acquainted with Central American cultures, spectacular landscapes and fascinating histories as you explore the wealth of ancient ruins, spot the range of unusual wildlife and relax on idyllic Caribbean shores. This is one of our longest adventures through Central America – a trip that zig-zags from the top of the Yucatan peninsula to the highlands of Costa Rica.

WildlifeCustom private toue

Tour Type

Small Group Tour

Accommodation

Hotel, Hut, Lodge

Age Range

15-99 yrs

Operated in

english

Destinations

Mexico City, San Jose, Palenque

Mexico City, San Jose, Palenque, Merida, Playa Del Carmen, Tulum, Caye Caulker, San Ignacio, Tikal, Rio Dulce, Antigua, San Jorge La Laguna, Panajachel, Puebla, Copan, Suchitoto, El Cuco, Leon, Granada, Ometepe Island, Monteverde Cloud Forest Biological Preserve, La Fortuna, Oaxaca, San Cristobal De Las Casas

13% OFF TODAY

Duration48 days

From

USD 8,115

USD 7,085

Saving

USD 1,030

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Rio De Janeiro, Iguazu Falls & Buenos Aires - October 2025

No booking fees

Best price guaranteed

Join us on this unique nine-day, guided tour to see the best of the Argentine and Brazil. Start your journey from Buenos Aires, Argentina's capital city, and cover some of the most important landmarks of this city before continuing to the mighty Iguazu Falls, a South American natural landmark that straddles two countries and draws countless visitors from all over the world each year. Spend three nights in Iguazu and enjoy the beauty of the waterfall from both Argentinian and the Brazilian side before heading for Rio de Janeiro. Spend the final few days of your trip exploring this delightful city and relaxing on its beaches. Please note that all flight tickets as well as entrances are not included in the tour price. For more details, please go through the itinerary below.

City sightseeing

Tour Type

Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Iguazu Falls, Rio de Janeiro

Duration9 days

From

USD 1,599

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Chile, Patagonian Lakes and Atacama Desert - October 2025

4.9

(17 reviews )

Trip customizable

Best price guaranteed

We had an amazing time on our trip to Chile. Everything on our itinerary was planned perfectly and everyone was early to arrive and very friendly and happy to give recommendations. The W Trek experience was made so much easier and less stressful thanks to their careful planning. Would recommend to anyone looking to experience Patagonia without having to worry about missing out on booking any part of the trip.

City sightseeingVolcanoes

Tour Type

Private Tour

Accommodation

Hotel

Age Range

1-79 yrs

Operated in

english, spanish

Destinations

Santiago, Puerto Varas, San Pedr

Santiago, Puerto Varas, San Pedro De Atacama, Moon Valley

Duration10 days

From

USD 2,940

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Natural Wonders of Argentina and Brazil - October 2025

4.7

(5 reviews )

Trip customizable

Best price guaranteed

The highlight of traveling with you was the promptness and timeliness of service. All Hotels were very good and our favourite excursion was at Iguazu Falls, it was very scenic. All the guides were very good, we are very pleased with the service. Everything was excellent.

City sightseeingNational parks

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Iguazu Falls, Rio

Buenos Aires, Iguazu Falls, Rio de Janeiro, Iguazu Falls National Park

Duration9 days

From

USD 2,730

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Luxury Food and Wine Tour of Argentina & Chile in 14 days - October 2025

(1 review )

Trip customizable

Best price guaranteed

Spend two weeks exploring the heart of Argentina's as well as Chile’s Southern lakes districts during this fabulous, guided tour. Enjoy the delights of Argentine and Chilean wines and gourmet food along with some of the best natural highlights of the area. Explore Buenos Aires, the 'Paris of South America', where you can enjoy an Argentine dinner along with local wines. Round it up with a stroll along Milongas. Discover Bariloche, the stunning lake region of Patagonia. Cross the Andes from Argentina to Chile enjoying amazing views of lakes, volcanoes and the majestic Andean Mountains. Learn more about the traditional gaucho way of life in San Antonio de Areco and visit ateliers and pulperias in the pampas. What are you waiting for? Book your tour today. See the itinerary for more details.

Wine tasting tours

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Mendoza

Buenos Aires, Santiago, Mendoza, Andes Mountains, Puerto Varas, Patagonia, San Carlos de Bariloche, Puerto Montt, Uco Valley, San Antonio De Areco, Pulperias, Isla Negra

Duration14 days

From

USD 12,600

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Super Sales

Costa Rica Experience - October 2025

No booking fees

Best price guaranteed

Discover a region of natural diversity, cultural riches and laidback vibes on an eight-day jungle jaunt through Costa Rica. Thanks to a longstanding tradition of preserving its natural assets, much of the country’s primary rainforest still stands. Opportunities for nature-based activities are endless here and the beaches on both coasts are well worth your free time. Spot monkeys and sloths in the cloud forests of Monteverde, hike to hidden waterfalls and kick back on the beach at Manuel Antonio. Explore the depths of this vibrant country with plenty of time to make this trip your own.

Active and outdoor

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

San Jose, Manuel Antonio Nationa

San Jose, Manuel Antonio National Park, La Fortuna, Monteverde Cloud Forest Biological Preserve, Arenal Volcano, Santa Rosa De Pocosol, Arenal, Quepos

Duration8 days

From

USD 1,140

USD 1,106

Saving

USD 34

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Central American Adventure - October 2025

13% OFF TODAY

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Central American Adventure - October 2025

(1 review )

No booking fees

Best price guaranteed

Explore colourful worlds – both on land and underwater – on a vibrant adventure from the sunny beaches of Mexico through jungle and Caribbean coastline to the volcanic mountains of Costa Rica. This 34-day adventure hits Mexico, Belize, Guatemala, Honduras, El Salvador, Nicaragua and Costa Rica, snaking through all the best spots and introducing you to local haunts as well as traveller hotspots. Discover a diverse marine playground in Caye Caulker, walk through the steamy cloud forests in Monteverde and visit the famous Tikal pyramids, arguably the most stunning of Guatemala’s ruins. Learn ancient Maya secrets and pass through jaw-dropping scenery on this Central American adventure.

Wildlife

Tour Type

Small Group Tour

Accommodation

Hotel, Hut, Lodge

Age Range

15-99 yrs

Operated in

english

Destinations

San Jose, Playa Del Carmen, Rio

San Jose, Playa Del Carmen, Rio Dulce, Antigua, San Jorge La Laguna, Panajachel, Copan, Suchitoto, El Cuco, Leon, Granada, Ometepe Island, Monteverde Cloud Forest Biological Preserve, Tulum, La Fortuna, Caye Caulker, San Ignacio, Tikal

13% OFF TODAY

Duration34 days

From

USD 4,985

USD 4,351

Saving

USD 634

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Argentina for true Explorers -15 days - October 2025

4.9

(17 reviews )

Trip customizable

Best price guaranteed

I usually don’t post reviews, but I wanted to thank the staff for helping to make our 2 week Argentinian adventure as flawless as possible. First Melina helped plan our itinerary, which was quite challenging since it included 4 flights and 5 hotels! The activities she suggested, from ice trekking to Tango shows were all fun and unique. The transportation to and from activities and hotels was stellar and such a time saver. We chose mid range hotels and each was clean and so fitting for the location we were at. Milagros took over once our itinerary was set and what a bonus that was! What stood out most was how graciously she accommodated all the issues we had once we began our trip - and there were a lot. From lost luggage to last minute flight and hotel changes, Milagros handled everything graciously and without an upcharge to do so. The farewell bottle of wine was such an unexpected surprise. Muchas Gracias, team!

Active and outdoor

Tour Type

Private Tour

Accommodation

Hotel, Tent

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Iguazu Falls, El C

Buenos Aires, Iguazu Falls, El Calafate, Ushuaia, El Chalten, Iguazu Falls National Park, Patagonia, Perito Moreno Glacier

Duration15 days

From

USD 3,285

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All South America Tours in October 2025

190 Trips in South America during October 2025 with 177 Reviews

190 Trips in South America during October 2025 with 177 Reviews

Central American Journey - October 2025

Exploring South America -13 days - October 2025

Highlights of Chile & Argentina - October 2025

Best of Argentina, Uruguay & Brazil - October 2025

Best of Brazil - October 2025

Best of South America - October 2025

Central America Explorer - October 2025

Rio De Janeiro, Iguazu Falls & Buenos Aires - October 2025

Chile, Patagonian Lakes and Atacama Desert - October 2025

Natural Wonders of Argentina and Brazil - October 2025

Luxury Food and Wine Tour of Argentina & Chile in 14 days - October 2025

Costa Rica Experience - October 2025

Central American Adventure - October 2025

Argentina for true Explorers -15 days - October 2025

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Asia

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Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All South America Tours in October 2025

190 Trips in South America during October 2025 with 177 Reviews

190 Trips in South America during October 2025 with 177 Reviews