10 Best Mendoza Multiday Tours in September 2025

Mendoza Wine & Mountains Adventure 4D/3N - September 2025

No booking fees

Best price guaranteed

Embark on a captivating journey through Mendoza's stunning landscapes, offering an unparalleled blend of wine and adventure. Savor world-class wines at renowned vineyards, explore the mesmerizing Andes Mountains, and indulge in gourmet cuisine set against picturesque backdrops. This immersive experience combines thrilling outdoor excursions with luxurious relaxation, perfect for wine enthusiasts and nature lovers alike. Whether you're hiking majestic trails or touring elegant wineries, this unforgettable adventure in Mendoza promises extraordinary memories and spectacular vistas.

AdventureTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Mendoza

Duration4 days

From

USD 602

View Tour

Wine and Landscapes of Argentina's Northwest - September 2025

4.8

(5 reviews )

No booking fees

Best price guaranteed

This was a fantastic trip that lived up fully to its billing, as we saw many spectacular and varied landscapes and we sampled many gorgeous wines. The guide Lucia was very knowledgeable and helpful throughout. My only observation is that it was a hard trip in terms of several very long days travelling of 8 or more hours - over 12 hours on one day - which meant we rarely had the chance to relax and/or enjoy the hotel facilities (e.g. pools in most hotels). The Trip Notes highlighted this but even so, after more than a dozen Explore trips previously which we thought prepared us for a lot of time on the road , we were still surprised. Essentially the trip was 12 full days and we thought it could have been stretched to 14 to cover the same itinerary - maybe an extra day in Cafayate and in Cachi? Why for example, did we travel from Mendoza to Aconcagua (a brilliant trip) but then back to Mendoza (3 hours each way) on one day, only to retrace our steps almost all the way back to Aconcagua on the next day, on the way to the next stop? This retracing of the same route wasted 6 hours, or almost a full day? Why did we not go from Aconcagua directly to the next stop, instead of back to Mendoza? In summary, this is a great tour, but we recommend you review the itinerary and through better planning and some extra time make it a more relaxing tour spread over over one or two more days.

Active and outdoorFood tours

Tour Type

Small Group Tour

Accommodation

Hotel, Villa

Age Range

16-79 yrs

Operated in

english

Destinations

Buenos Aires, Cafayate, Mendoza

Buenos Aires, Cafayate, Mendoza, Salta, Humahuaca, Barreal, Villa Union, Belen, Cachi

Duration14 days

From

USD 4,520

View Tour

Santiago to Rio de Janeiro Travel Pass - September 2025

No booking fees

Best price guaranteed

Discover South America's majestic wonders on an unforgettable adventure from Santiago to Rio de Janeiro. Experience the thrill of hiking in Chile's picturesque landscapes, exploring Buenos Aires' vibrant culture, and soaking in Iguazu Falls' breathtaking views. With immersive local activities, cultural encounters, and scenic routes, this tour offers a perfect blend of nature and urban excitement. Ideal for travelers eager to uncover hidden gems, this journey promises an enriching and exhilarating exploration of diverse cultures and stunning scenery. Embark on the ultimate South American expedition today!

Local boat rides

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro, Puerto

Santiago, Rio de Janeiro, Puerto Iguazu, Florianopolis, Sao Paulo, Paraty, Mendoza, Ilha Grande, Córdoba, Buenos Aires

Duration25 days

From

USD 1,723

View Tour

Premium Chile, Argentina & Brazil - September 2025

13% OFF TODAY

Super Sales

Premium Chile, Argentina & Brazil - September 2025

No booking fees

Best price guaranteed

Soak up the warmth and charm of Chile, Argentina and Brazil on a 15-day Premium adventure. Pick up the tempo in artistic Santiago, travel through colourful Valparaiso, cross into Mendoza - the home of Argentinian Malbec, then get swept up in the tantalising mix of European and Latin flair in Buenos Aires. At the border with Brazil, experience the magnificent might of Iguazu Falls, before finally arriving in one of the most beautiful cities in the world, Rio de Janeiro. Travel with passionate local leaders who will reveal the sights, sounds and tastes of their homelands.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro, Buenos

Santiago, Rio de Janeiro, Buenos Aires, Puerto Iguazu, Valparaiso, Mendoza

13% OFF TODAY

Duration15 days

From

USD 10,545

USD 9,205

Saving

USD 1,340

View Tour

Argentina Family Trip - September 2025

Trip customizable

Best price guaranteed

Get ready to enjoy a memorable trip with your family. Start your journey with a sightseeing tour of Buenos Aires and learn more about the history of this city. Located in Argentina's Río Negro province, Bariloche, another highlight of this trip, is a city surrounded by thousand-year-old forests, mountains covered in snow and crystal clear lakes. Mendoza, on the other hand, is a famous wine region in Argentina. A particularly famous specialty of the region is the tasty red Malbec. Also included in the itinerary are a variety of activities ranging from glacier walk to kayaking and hiking through forests. Please scroll down to the itinerary section for more details.

Trekking and Hiking

Tour Type

Private Tour

Accommodation

Hotel

Age Range

1-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Mendoza, Patagonia

Buenos Aires, Mendoza, Patagonia, San Carlos de Bariloche

Duration10 days

From

USD 3,460

View Tour

Rio de Janeiro to Santiago Travel Pass - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Rio de Janeiro to Santiago, exploring South America’s vibrant culture and breathtaking landscapes. Dive into lively Rio’s beaches, marvel at Iguazu Falls’ natural wonders, and revel in Buenos Aires’ rich history. Experience Chile’s scenic beauty in Colchagua Valley and the energetic atmosphere of Santiago. Perfect for thrill-seekers and cultural enthusiasts, enjoy unique excursions including wine tasting and tango dancing lessons. Discover the essence of South America with this curated travel experience.

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro, Floria

Santiago, Rio de Janeiro, Florianopolis, Foz Do Iguacu, Puerto Iguazu, Buenos Aires, Córdoba, Mendoza, Ilha Grande, Paraty, Sao Paulo

Duration21 days

From

USD 1,779

View Tour

North Argentina Adventure 17D/16N - September 2025

No booking fees

Best price guaranteed

Embark on an exhilarating North Argentina adventure, exploring the stunning landscapes of Salta, Jujuy, and beyond. Delve into the vibrant culture of Buenos Aires, marvel at the otherworldly Quebrada de Humahuaca, and traverse the breathtaking Calchaquí Valleys. This immersive experience offers wine-tasting in Cafayate, guided hikes, and interactions with local communities. Ideal for nature lovers and cultural enthusiasts alike, this journey guarantees unforgettable memories amidst Argentina's most iconic and diverse regions. Discover the beauty of North Argentina today!

AdventureTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Mendoza, Salta, Puerto Iguazu

Duration17 days

From

USD 2,328

View Tour

Santiago to Buenos Aires (via Mendoza) Travel Pass - September 2025

No booking fees

Best price guaranteed

Discover an unforgettable adventure from Santiago to Buenos Aires, immersing yourself in the rich culture and breathtaking landscapes of South America. Journey through the scenic Andes, savor exquisite wines in Mendoza, and experience vibrant city life in Buenos Aires. This curated travel pass offers guided tours, diverse outdoor activities, and authentic local experiences. Perfect for wine enthusiasts and adventure seekers, this tour offers the ultimate blend of nature, culture, and culinary delights. Book now for an extraordinary South American escapade!

Adventure

Tour Type

Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Mendoza

Buenos Aires, Santiago, Mendoza, Córdoba

Duration7 days

From

USD 505

View Tour

Buenos Aires to Santiago (via Mendoza) Travel Pass - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable journey from Buenos Aires to Santiago, immersing yourself in local culture and breathtaking landscapes. Enjoy wine tasting in Argentina's famed Mendoza region, marvel at the Andes’ majestic beauty, and discover vibrant cities bursting with history, art, and gastronomy. Perfect for adventure seekers and culture enthusiasts, this travel pass offers a seamless blend of city life and scenic wonders. Don't miss this chance to explore South America's most dynamic destinations.

Explorer

Tour Type

Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Córdoba

Buenos Aires, Santiago, Córdoba, Mendoza

Duration7 days

From

USD 540

View Tour

All Mendoza Tours in September 2025

9 Trips in Mendoza during September 2025

9 Trips in Mendoza during September 2025

Mendoza Wine & Mountains Adventure 4D/3N - September 2025

Wine and Landscapes of Argentina's Northwest - September 2025

Santiago to Rio de Janeiro Travel Pass - September 2025

Premium Chile, Argentina & Brazil - September 2025

Argentina Family Trip - September 2025

Rio de Janeiro to Santiago Travel Pass - September 2025

North Argentina Adventure 17D/16N - September 2025

Santiago to Buenos Aires (via Mendoza) Travel Pass - September 2025

Buenos Aires to Santiago (via Mendoza) Travel Pass - September 2025

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Mendoza Tours in September 2025

9 Trips in Mendoza during September 2025

9 Trips in Mendoza during September 2025