Czech Republic in 6 Days: 4 Recommended 6-day Itineraries to Czech Republic

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Czech Republic 6-Day Itinerary Options
Check out our exciting Czech Republic 6 days’ itinerary suggestions below. Whether you're an art lover, history buff, or outdoor enthusiast, these plans cater to a variety of interests and preferences.
Itinerary #1: Classic Prague and Beyond


Overview | Activity | Overnight | |
Day 1 | Arrive in Prague, begin with a sightseeing tour | City sightseeing | Prague |
Day 2 | Discover Prague Castle and Charles Bridge | City landmark sightseeing | Prague |
Day 3 | Day trip to Český Krumlov | City exploration | Český Krumlov |
Day 4 | Return to Prague for further cultural insights and local cuisine | City exploration | Prague |
Day 5 | Explore Kutná Hora | City sightseeing | Prague |
Day 6 | Say good bye to Prague |
This 6-day Czech Republic itinerary provides a perfect blend of Prague's iconic sights with a day trip to Český Krumlov, a Unesco World Heritage Site known for its stunning castle and historic center. Get captivated by Prague's rich history as you wander through its cobbled streets, visiting landmarks like Prague Castle, the bustling Charles Bridge, and the intriguing Astronomical Clock in the Old Town Square. A short trip to Kutná Hora offers a fascinating glimpse into the past with its medieval architecture and the world-renowned Sedlec Ossuary. For more inspiration on exploring the country, see all tours in the Czech Republic.
Itinerary #2: Bohemian and Moravian Adventure

Overview | Activity | Overnight | |
Day 1 | Start your journey in Prague with boat cruise on the Vltava | City exploration | Prague |
Day 2 | Set off to Český Krumlov | Castle visit and riverside stroll | Český Krumlov |
Day 3 | Travel to Brno, the heart of Moravia | City exploration | Brno |
Day 4 | Explore Brno's cultural landscape | City exploration | Brno |
Day 5 | Travel to Lednice-Valtice Cultural Landscape | Castle visits | Brno |
Day 6 | Return to Prague for departure |
Experience the captivating contrasts of Bohemia and Moravia on this immersive journey through the Czech Republic. Begin with a tour of Prague, where a scenic boat cruise along the Vltava River sets the stage for exploring the city's rich history and vibrant atmosphere. Venture south to the storybook town of Český Krumlov, with its medieval charm and picturesque streets. Continue east to Brno, a city that blends architectural elegance with cultural depth—visit the modernist Villa Tugendhat, the imposing Špilberk Castle, and the bustling local markets near the Cathedral of St. Peter and Paul. Take a day trip to Mikulov, where rolling vineyards, Baroque architecture, and the Unesco-listed Lednice-Valtice Cultural Landscape create a perfect setting for wine lovers and history enthusiasts alike. End your journey back in Prague, where one last stroll through its enchanting streets wraps up this adventure.
Itinerary #3: Czech Spa Towns and Nature Retreat


Overview | Activity | Overnight | |
Day 1 | Begin in the historic city of Karlovy Vary | Local culture tour | Karlovy Vary |
Day 2 | Explore Karlovy Vary's scenic landscapes | Nature exploration | Karlovy Vary |
Day 3 | Travel to Mariánské Lázně | Nature exploration | Mariánské Lázně |
Day 4 | Discover the beauty of Bohemian Forest | Hiking | Železná Ruda |
Day 5 | Head towards Plzeň | City exploration | Plzeň |
Day 6 | Make your way to Prague for departure |
Indulge in a rejuvenating escape through the Czech Republic’s renowned spa towns and breathtaking natural landscapes. Begin in Karlovy Vary, where elegant colonnades and mineral-rich hot springs invite relaxation. Stroll along the Teplá River, admire the town’s grand architecture, and experience the healing waters at one of its famous spas. Next, journey to Mariánské Lázně, a haven of tranquility offering therapeutic treatments and peaceful forest trails. Continue to the Bohemian Forest, where scenic hikes and birdwatching immerse you in unspoiled nature. Before returning to Prague, visit Plzeň, the birthplace of Pilsner beer—tour a historic brewery and enjoy a tasting of the world-famous brew.
Itinerary #4: A Culinary and Cultural Quest in the Czech Republic


Overview | Activity | Overnight | |
Day 1 | Arrive in Prague and explore its vibrant food scene | Food tour | Prague |
Day 2 | Dive into Prague's cultural landscape | Culture tour | Prague |
Day 3 | Travel to Olomouc | City exploration | Olomouc |
Day 4 | Discover Olomouc's historic sites | Culture and history tour | Olomouc |
Day 5 | Visit the Moravian Wine Region | Wine tasting | Mikulov |
Day 6 | Return to Prague for your flight home |
This 6-day itinerary is perfect for food lovers and culture enthusiasts seeking a deeper connection with the Czech Republic. Begin in Prague, where a guided food tour introduces you to the country’s rich culinary traditions. The next day, explore the city's cultural landmarks before heading to Olomouc, a hidden gem known for its baroque architecture and famous Olomouc cheese. Immerse yourself in history before traveling to the Moravian Wine Region, where rolling vineyards and exquisite wines await. Conclude your journey in Mikulov, savoring local flavors before returning to Prague. A perfect mix of gastronomy, heritage, and scenic charm.
Planning a 6-day itinerary of the Czech Republic?
Embarking on a journey through the Czech Republic in 6 days allows you to get a good glimpse of its cultural and historical landscapes. Whether you opt for a relaxing retreat or a delicious culinary adventure, there's plenty to explore. Curious to learn more before booking that trip? Check out our guide on the best time to visit the Czech Republic. Also go through the optimum durations to spend in the Czech Republic for more inspiration.
More information:
7 days in Czech Republic
10 days in Czech Republic
5 days in Czech Republic
4 days in Czech Republic