Czech Republic in 5 Days: 2 Recommended 5-day Itineraries to Czech Republic

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Czech Republic 5-Day Itinerary Options
With 5 days in the Czech Republic, you can explore amazing cities like the capital, Prague, check out the second city of Brno, or dive into the culture and festivals of beautiful Central Europe.
Itinerary #1: Explore Prague

Overview | Activity | Overnight | |
Day 1 | Wander around Prague’s Old Town | Sightseeing | Prague |
Day 2 | Explore Prague Castle | Sightseeing | Prague |
Day 3 | Indulge in a museum day in the Jewish Quarter | Culture | Prague |
Day 4 | Spend a day trip in Kutná Hora | Culture | Prague |
Day 5 | Shop until you drop | Shopping & departure |
Enjoy five history-packed days in Prague. Start off your journey in the heart of Prague’s Old Town. Spend some time wandering across the Charles Bridge and check out the engineering marvel of the Astronomical Clock. Move onwards to the splendor of Prague Castle before hitting the Lesser Town (Malá Strana). Here, you can visit St. Nicholas Church and the hidden gardens and find a tranquil space in the middle of the city. Next, embark on a walking tour of the Jewish Quarter, where you can visit the Old Jewish Cemetery and synagogues. After some delicious lunch, check out the city’s amazing museums like the National Museum and the Museum of Communism. The next day, leave the city behind for the UNESCO World Heritage Site of Kutná Hora. Famous for the silver mines, Sedlec Ossuary, and St. Barbara’s Church, it’s a beautiful place to spend the day. Spend your final hours in Prague shopping around the Letná Park neighborhood before enjoying a dinner cruise along the Vltava. See all tours in the Czech Republic.
Itinerary #2: Highlights of Brno

Overview | Activity | Overnight | |
Day 1 | Explore the stunning Špilberk Castle | Sightseeing | Brno |
Day 2 | Wander around the artistic neighborhoods and visit Villa Tugendhat | Culture | Brno |
Day 3 | Paddleboard or kayak on the Brno Reservoir | Nature | Brno |
Day 4 | Enjoy a food and drink tour before visiting Brno Ossuary | Food and Sightseeing | Brno |
Day 5 | Travel on a day trip to Moravian Karst | Nature & departure |
If you want to spend 5 days in the Czech Republic’s second city, Brno, there are plenty of things to see and do. Start your adventure off with some top-tier sightseeing including the historic Špilberk Castle, and the Cathedral of St. Peter and Paul, and spend time in Old Town Square with its colorful buildings. Next, indulge in the Brno art scene with visits to the Moravian Gallery and the UNESCO World Heritage Site of Villa Tugendhat, with its amazing architecture. On the next day, leave the city behind for the calming and tranquil Brno Reservoir. Here, you can hire a paddleboard or kayak, or relax on the shore in the sunshine. Return to Brno and embark on a food and drink tour, enjoying the traditional Czech breweries and eating goulash and dumplings. Spend the afternoon at Brno Ossuary, a 17th-century crypt, filled with human remains. On the last day, visit the natural wonder of Moravian Karst. Home to the Punkva Caves and the Macocha Abyss, it’s a geological marvel and a relaxing place to end your trip.
Planning a Czech Republic 5-Day Itinerary?
With 5 days in the Czech Republic, you can easily check out beautiful historic cities like Prague and Brno and enjoy day trips out into nature like Brno Reservoir and the relaxing cultural hotspots like Kutná Hora. From historic walking tours of UNESCO heritage sites to delicious brewery tours, there are plenty of vibes to choose from.
If you have slightly longer to spend in the Czech Republic, check out our 10-day itineraries for more inspiration. Need a helping hand organizing and booking your trip? Our in-country travel experts are on hand to help create personalized Czech Republic itineraries that suit all your needs.
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