10 Best South America Multiday Tours in October 2025

Private Machu Picchu Full Day Tour - October 2025

(24 reviews )

Trip customizable

Best price guaranteed

It is truly an experience that should be cherished and embraced at least once in a lifetime. We were incredibly fortunate to have been blessed with a sunny day, which enhanced the perfection of every moment.

Cultural, religious and historic sites

Tour Type

Private Tour

Accommodation

Hotel

Age Range

1-79 yrs

Operated in

english, portuguese, spanish

Destinations

Cusco, Machu Picchu, Aguas Calientes

Duration1 day

From

USD 390

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Journeys: Highlights Of Bolivia - October 2025

27% OFF TODAY

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Journeys: Highlights of Bolivia - October 2025

(7 reviews )

No booking fees

Best price guaranteed

Excellent choice. Vlad had been wonderful !

Natural landmarks sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

12-100 yrs

Operated in

english

Destinations

La Paz, Sucre, Potosi, Uyuni

27% OFF TODAY

Duration8 days

From

USD 2,799

USD 2,036

Saving

USD 763

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Uyuni Salt Flats & Desert Adventure 5D/4N (La Paz to La Paz) - October 2025

(2 reviews )

No booking fees

Best price guaranteed

Embark on a captivating expedition through Uyuni’s mesmerising landscapes, including the enchanting Train Cemetery, dazzling salt flats, vibrant lagoons, and striking geologic formations. Witness spectacular wildlife like flamingos, relax in soothing thermal waters, and spend immersive nights in the singular salt hotel and a remote hostel. This journey promises a blend of natural wonders and cultural richness, offering an unforgettable experience.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Uyuni, Candelaria, Polques

Duration5 days

From

USD 480

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Deserts, Jungle and Wine - October 2025

(14 reviews )

Trip customizable

Best price guaranteed

The team really put together a great itinerary that takes you to meet the natural beauty of Argentina. Our adventure through the Humahuaca Gorge was an absolute highlight. The stunning landscapes and vibrant colors of the mountains left me in awe. The serenity of the Andes, the crystal-clear mountain lakes, and the rugged terrain all combined to create a truly remarkable experience. The Tango show and dinner experience was truly the cherry on top of our time in Buenos Aires. It was an emotional journey into the heart and soul of Argentina, a performance that left us spellbound and filled with appreciation for the country's culture. I can't thank enough the team for the memories I've made.

Natural landmarks sightseeing

Tour Type

Private Tour

Accommodation

Hotel, Resort

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Mendoza, Salta, Pu

Buenos Aires, Mendoza, Salta, Purmamarca, Calchaquies Valley, Humahuaca, Calchaqui Valley

Duration12 days

From

USD 5,560

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Journeys: Explore Machu Picchu - October 2025

13% OFF TODAY

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Journeys: Explore Machu Picchu - October 2025

(8 reviews )

No booking fees

Best price guaranteed

Stellar travel experience that pushed me beyond my own limits, provided opportunities that would not otherwise been achievable, while still providing me the confidence in being safe. The experience was well beyond what I anticipated, and delivered to a level that impressive.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

12-100 yrs

Operated in

english

Destinations

Lima, Urubamba, Aguas Calientes

Lima, Urubamba, Aguas Calientes, Cusco

13% OFF TODAY

Duration8 days

From

USD 2,499

USD 2,182

Saving

USD 317

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27% OFF TODAY

Super Sales

Ecuador Quest - October 2025

(4 reviews )

No booking fees

Best price guaranteed

My trip to Ecuador quest tour was absolutely amazing. I honestly came in with no idea what to expect and but after the tour was pleasantly surprised. The tour takes you to a variety of locations across the highlands and the jungle and each destination provided me with a unique memory and experience to take home. This trip is super duper affordable and your money goes a long way in the country for food and souvenirs and everything in between. I particularly loved all the adventures we did in BaA±os which included Horseback Riding and ziplining for $25 each. Our CEO Carlos was great and was a go to resource. Ecuador is a beautiful country with such friendly people and great food. Highly recommend!

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Hut, Home-stay

Age Range

12-100 yrs

Operated in

english

Destinations

Quito, Banos, Tena, Papallacta

27% OFF TODAY

Duration8 days

From

USD 1,099

USD 799

Saving

USD 300

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Mountains & Volcanos of Costa Rica - October 2025

Trip customizable

Best price guaranteed

Join us for this magical 7-day mountain and volcano tour! Visit some of the highlights of Costa Rica on this semi-guided trip, where you can enjoy both free independent time and the benefits of local guides for certain activities. Start the tour with a pick-up in San Jose and transfer to the famed Monteverde, where you'' have a chance to explore the cloud forest and take a heart-pumping copy zipline ride on the longest zipline in the country! Then visit La Fortuna and spend a day on Arenal Volcano. Don't forget a soak in the hot springs! Next head to the jungles of Tortuguero National Park REserve where you can search for birds and wildlife on a relaxing morning canoe ride. After Tortuguero, transfer back to San Jose where the trip ends.

AdventureSightseeing Tours

Tour Type

Private Tour

Accommodation

Eco Lodge, Hotel, Lodge

Age Range

15-79 yrs

Operated in

english, spanish

Destinations

San Jose, La Fortuna, Tortuguero

San Jose, La Fortuna, Tortuguero National Park, Monteverde Cloud Forest Biological Preserve

Duration7 days

From

USD 1,000

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Easter Island Experience 4D/3N - October 2025

(1 review )

No booking fees

Best price guaranteed

Discover the ancient wonders of Easter Island with an immersive adventure that showcases iconic moai statues, volcanic landscapes, and rich cultural heritage. Embark on guided tours to Rano Raraku, Orongo Ceremonial Village, and Anakena Beach, uncovering the mysteries of this remote Pacific island. Enjoy unique encounters with local traditions, folklore, and breathtaking natural beauty. This unforgettable journey offers a perfect blend of history, stunning vistas, and authentic experiences, making it a must-visit for travel enthusiasts seeking extraordinary destinations.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Easter Island, Ahu Akivi, Anaken

Easter Island, Ahu Akivi, Anakena Beach, Orongo, Hanga Roa

Duration4 days

From

USD 1,044

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Tango, Wine & Blue water dreams - October 2025

(13 reviews )

Trip customizable

Best price guaranteed

Nearly all of the guides were wonderful. I don’t remember the name of the guide who took us to El Chaltén but we appreciated that he took us seriously as trekkers and suggested a slightly longer trek with beautiful views. We thoroughly enjoyed that trek! And we also were very happy with our guide in Tiera del Fuego. She was very lively, knowledgeable and provided us with a couple of wonderful hike and a delicious lunch. We loved all she knew about the birds, trees and geology on the area."

City sightseeing

Tour Type

Private Tour

Accommodation

Hotel, Resort

Age Range

1-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Iguazu Falls, Mend

Buenos Aires, Iguazu Falls, Mendoza, Patagonia, San Carlos de Bariloche

Duration12 days

From

USD 3,695

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Argentina Nature Wonders - October 2025

4.5

(6 reviews )

Trip customizable

Best price guaranteed

Top notch service from this company which I chose for our Argentina trip because they're based in Buenos Aires and have a focus on South America. Clara Gonzalez crafted an experience perfectly in line with our request and did so quickly and accurately. Antonella Pascarelli provided us with the expert support we needed before and during the trip. She informed us of needed documentation, answered detailed questions about hotels and restaurants, handled all hotel stays accurately and made dinner reservations at our choice of restaurants. Land transfers were crucial to our moving about the country and the app included necessary information about that. The guides (Diana in Buenos Aires; Shoam in El Chalten) were both well informed, efficient and personable. I'm glad Antonella knew which companies with whom to work. When we were in country, I received daily emails from Antonella checking in on how things were going and making sure we were on track with the next phase of the trip. I would like to return to South America and I will most certainly try to work with with them.

City sightseeing

Tour Type

Private Tour

Accommodation

Hotel, Tent

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Patagonia, Perito

Buenos Aires, Patagonia, Perito Moreno Glacier, Iguazu Falls, Ushuaia, Beagle Channel Cruise, El Calafate

Duration12 days

From

USD 3,060

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Costa Rican Adventure - October 2025

(1 review )

Trip customizable

Best price guaranteed

We started off San Jose and explored the culture. Food was amazing. Next we headed out to Pacuera River to whitewater raft for two days. Got to stay in the rainforest with huts and the guides/volunteers were Amazing. So attentive, knowledgeable and kind. They kept us well fed. Our next trip took us to LA Fortuna....long drive but worth it. The hanging bridges, waterfall, and hot springs all were very enjoyable. We were lucky enough to see spider monkeys and other native wildlife ssooo cool! We then went to Quepas near Manuel Antonio to enjoy the Pacific beach. Beautiful as well. The water is very warm. Other wildlife we saw were macaws, iguanas, chipocun monkeys. Last destination back to San Jose. Enjoyed walking around the market streets. Our drivers, guides, and meals were all great.

Rafting

Tour Type

Small Group Tour

Accommodation

Hotel, Camping

Age Range

13-79 yrs

Operated in

english, spanish

Destinations

San Jose, Manuel Antonio Nationa

San Jose, Manuel Antonio National Park, Arenal Volcano, Pacuare River, Arenal, Manuel Antonio

Duration8 days

From

USD 1,350

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Discover Pantanal, Rio & Costa Verde - October 2025

Trip customizable

Best price guaranteed

Discover some of Brazil's most beautiful places during this 14-day, private tour. We will drive you to Campo Grande to Pousada Aguape on arrival. Pousada Aguape is located on the edge of the Pantanal, a natural region encompassing the world's largest tropical wetland area. Next on the itinerary is Rio De Janeiro, a costal metropolis known for its Copacabana and Ipanema beaches, the statue of Christ the Redeemer atop Mount Corcovado as well as Sugarloaf Mountain. Enjoy a sightseeing tour of this city and take a cable car to Sugarloaf Mountain. Also hike the Pedra Bonita trail while enjoying amazing views of the city below. Head for Paraty, a colonial town and a Unesco Word Heritage site that represents Brazil’s colonial heritage, next. Explore the area around Paraty during a sightseeing tour and hike to the famous beach of Ponta Negra. Your last destination on the itinerary is Ilha Grande, a beautiful island surrounded by beaches, covered by forests and crisscrossed by winding trails. From there you will take a speedboat followed by a private vehicle to Rio de Janeiro at the end of the tour. For more details, please go through the itinerary below.

City sightseeing

Tour Type

Private Tour

Accommodation

Hotel

Age Range

1-80 yrs

Operated in

english

Destinations

Rio de Janeiro, Paraty, Pantanal

Rio de Janeiro, Paraty, Pantanal, Campo Grande, Ilha Grande, Pousada Aguapé

Duration14 days

From

USD 2,365

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Iguazu Falls Private Day Trip from Buenos Aires with Airfare - Argentinian Side - October 2025

Trip customizable

Best price guaranteed

If you are visiting Buenos Aires, and you just have one day off to visit Iguazu Falls, this tour is what you need, as it lets you explore the Iguazu Falls National Park in one day. You will take an early flight from the domestic airport in Buenos Aires direct to Puerto Iguazu, where you will be welcomed by one of our tour guides, who will be escorting you during the whole day, making you enjoy your full day visit to the Argentine Iguazu Falls National Park. Late in the afternoon, you will be taken back to the airport, to get your flight back to Buenos Aires

Waterfalls

Tour Type

Private Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires

Duration1 day

From

USD 1,541

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11 Days: The Magic of the Andes - October 2025

Trip customizable

Best price guaranteed

Discover the magic of Peru on this comprehensive 11-day tour that takes you through ancient civilizations, modern cultures, architectural wonders and stunning landscapes! Start in Lima and visit the historic downtown before heading off to Cusco, where you will feel the magic reverberating in this sacred Inca city. Pass through the stunning Sacred Valley of the Inca, interact with a living ancient culture, and arrive at the enigmatic and iconic city of Machu Picchu. Explore Ollyatomabo, Moray and Pisac. Then, navigate Lake Titicaca through the inhabited floating islands of the Uros and experience a unique homestay on the island of Taquile. Don’t miss out on this incredible experience through the Peruvian Andes! During this experience, you will be fully accompanied by the best guides who are professionals ready to serve you at every moment. All transportation, domestic flights, accommodation and some meals are included. Please see the itinerary and what’s included sections for more details on the activities and locations.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Home-stay

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Cusco, Machu Picchu, Lima, Puno

Cusco, Machu Picchu, Lima, Puno, Ollantaytambo, Pisac, Amantani, Aguas Calientes, Maras & Moray, Chinchero District

Duration11 days

From

USD 2,899

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All South America Tours in October 2025

Page 14 of 1,504 Trips in South America during October 2025 with 2,211 Reviews

Private Machu Picchu Full Day Tour - October 2025

Journeys: Highlights of Bolivia - October 2025

Uyuni Salt Flats & Desert Adventure 5D/4N (La Paz to La Paz) - October 2025

Deserts, Jungle and Wine - October 2025

Journeys: Explore Machu Picchu - October 2025

Ecuador Quest - October 2025

Mountains & Volcanos of Costa Rica - October 2025

Easter Island Experience 4D/3N - October 2025

Tango, Wine & Blue water dreams - October 2025

Argentina Nature Wonders - October 2025

Costa Rican Adventure - October 2025

Discover Pantanal, Rio & Costa Verde - October 2025

Iguazu Falls Private Day Trip from Buenos Aires with Airfare - Argentinian Side - October 2025

11 Days: The Magic of the Andes - October 2025

Page 14 of 1,504 Trips in South America during October 2025 with 2,211 Reviews

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All South America Tours in October 2025

Page 14 of 1,504 Trips in South America during October 2025 with 2,211 Reviews

Page 14 of 1,504 Trips in South America during October 2025 with 2,211 Reviews