10 Best South America Multiday Tours in May 2026

5% OFF TODAY

Mountains and Glaciers: El Calafate and Torres del Paine - May 2026

(4 reviews )

Trip customizable

Best price guaranteed

My trip to Patagonia was one of the best that I have ever done. The landscapes and the people were something that I would never forget. El Calafate was absolutely beautiful, full of lakes and glaciers. Perito Moreno Glacier is unique and a must if you are travelling to Argentina. I also booked the full day tour to El Chalten, which is very nice but I would have preferred to stay for a few nights in the village to do some of the treks in the area but I did not have many days. I stayed at Hotel Mirador del Lago which has amazing views of Argentino lake. Torres del Paine National Park was equally amazing. Our guide Lucas was incredible and very knowledgeable. Hotel Altiplanico was so beautiful. 100% recommend this tour.

Trekking and HikingExplorer

Tour Type

Independent Tour

Accommodation

Camping, Hotel

Age Range

1-99 yrs

Operated in

english, spanish

Destinations

Torres del Paine National Park

Torres del Paine National Park, Puerto Natales, Perito Moreno Glacier, El Calafate, Punta Arenas

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Duration7 days

From

USD 1,980

USD 1,881

Saving

USD 99

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5% OFF TODAY

Ecuador - Andes to Amazon - May 2026

4.8

(8 reviews )

No booking fees

Best price guaranteed

This was one of the best "Discovery" tours I have been on with Explore. It felt like a real adventure, with the excursions to the volcanoes Cotopaxi and Chimborazo and the boat trips on the Napo river, a tributary of the Amazon. Our tour leader, Fabian, and driver, William, were both excellent. The accommodation was generally very good, with the exception being the Riobamba hotel. I find the comments by a previous reviewer about the current power outages in Ecuador to be absurd. The outages were a mild inconvenience (to us - although I pity the Ecuadorian people) but there were absolutely no security or food safety issues as a result. When I travel in (e.g.) South America I don't expect everything to be just like it is in my cosy Western European home! My one criticism of this trip is that there were far too many shopping stops that were thinly disguised as "cultural visits" - I counted at least ten of these. The number should be at least halved. I mean, what on earth do painted balsa wood parrots have to do with the culture of Ecuador? Or carved nut kernels, for that matter?

Active and outdoorExplorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

16-99 yrs

Operated in

english

Destinations

Quito, Guayaquil, Riobamba, Cuen

Quito, Guayaquil, Riobamba, Cuenca, Otavalo, Peguche, Cotopaxi National Park, Tena, Misahualli, Misicocha, Banos

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Duration14 days

From

USD 2,760

USD 2,622

Saving

USD 138

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3 Day Wine & Dine Tour: Colchagua Valley - May 2026

Trip customizable

Best price guaranteed

Indulge yourself! This Colchagua three-day wine and dine tour is the perfect excuse to treat yourself to a weekend of wine and fine cuisine or the ideal romantic getaway with your partner. Spend three days in the beautiful valley of Colchagua. Fill your time with wine tastings, strolls through the vineyards, sampling the fine dining, and even a horseback ride if you choose. Personalize your trip by choosing either to spend the night in a boutique hotel in the Santa Cruz area or enjoying nature in a cosy countryside lodge. The Colchagua Valley is located approximately 180 km south of Santiago and is one of Chile's best-known wine areas! The area has won various awards for their full-bodied cabernet sauvignons, malbecs, merlots, syrahs and carménères. Despite a calm rural oasis atmosphere, the area has a rich culture and history. Come and experience this wonderful region!

Wine tasting toursFood tours

Tour Type

Private Tour

Accommodation

Lodge, Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Santiago, Colchagua Valley

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Duration3 days

From

USD 965

USD 917

Saving

USD 48

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5% OFF TODAY

Ushuaia & El Calafate Tour - May 2026

No booking fees

Best price guaranteed

Join us on this six-day, group tour that is the perfect combination of two amazing destinations in Argentina: Ushuaia, the southernmost city in the world, and El Calafate, a town near the Southern Patagonian Ice Field. We will pick you up on arrival in Ushuaia. Visit Tierra del Fuego National Park and see Bahia Lapataia as well as Lake Roca among other highlights before returning to the city to enjoy a Beagle Channel navigation by boat. See Bird´s Island, Sea Lion´s Island and Les Eclareirs Lighthouse. Head for El Calafate, home to the incredible Perito Moreno Glacier, Argentino Lake and Los Glaciares National Park. See Perito Moreno and explore Los Glaciares before its time to head home. Please note that domestic flights and national park entrance fees are not included in the tour price. For more details, please go through the itinerary below.

National parks

Tour Type

Group Tour

Accommodation

Hotel

Age Range

11-99 yrs

Operated in

English

Destinations

El Calafate, Ushuaia, Patagonia

El Calafate, Ushuaia, Patagonia, Perito Moreno Glacier

5% OFF TODAY

Duration6 days

From

USD 939

USD 892

Saving

USD 47

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Simply Peru - May 2026

4.7

(12 reviews )

No booking fees

Best price guaranteed

Tour leader was friendly approachable knowledgeable. She took great care of us. Full on tour but that was just what I wanted.

Active and outdoorExplorer

Tour Type

Small Group Tour

Accommodation

Hotel, Guest House

Age Range

16-99 yrs

Operated in

english

Destinations

Cusco, Lima, Machu Picchu, Sacre

Cusco, Lima, Machu Picchu, Sacred Valley, Nazca, Arequipa, Chivay, Puno, Taquile Island

5% OFF TODAY

Duration14 days

From

USD 2,080

USD 1,976

Saving

USD 104

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The Ultimate Trek to Machu Picchu: Salkantay Trek 5 Days - May 2026

Trip customizable

Best price guaranteed

Salkantay Trek is a popular alternative to the very-crowded classic Inca Trail. It offers more distance, more mountains, more scenery, and a wider variety of landscapes, but still concludes with a visit to the iconic city of Machu Picchu. As the route does not have as many regulations as the Inca Trail, this also means that it can provide a “back door” trek to Machu Picchu when Inca Trail permits are sold out. This new itinerary, Salkantay Trek to Machu Picchu via Llaqtapata, includes the highlights of the other Salkantay trek, but avoids many of the areas that are becoming crowded with other trekkers. This trip is fully-inclusive, including a guide, accommodation, meals and transportation. Duration: 5 days/4 nights Distance trekked: about 50km Elevation: 1900-4600m Difficulty: Moderate Crowds: Moderate

Trekking and HikingMountains

Tour Type

Small Group Tour

Accommodation

Tent, Hotel, Camping

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Salkantay, Cusco, La Playa, Aguas Calientes

5% OFF TODAY

Duration5 days

From

USD 765

USD 727

Saving

USD 38

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14% OFF TODAY

Volcanoes and Galapagos - May 2026

4.9

(28 reviews )

No booking fees

Best price guaranteed

Really enjoyed the variety of things to see and do. Galapagos Islands were amazing and pleased to see that they are trying hard to protect the local environment and native animals and educate the next generation. Loved the giant tortoises and the way local rangers are protecting them from extinction from hand rearing eggs to releasing them when they are older. Blue footed Boobies were a highlight of mine to see, only wish I had seen the red footed boobies as well. The visit to the rose farm was an eye opener as I hadn't realised that Ecuador was such a productive place for roses and exportation, the employees all looked happy and relaxed. Interesting visit to Condor sanctuary and the way they are rehabilitating injured birds and introducing them into the countryside.

Active and outdoorWildlife

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

16-99 yrs

Operated in

english

Destinations

Quito, Guayaquil, Sierra Negra

Quito, Guayaquil, Sierra Negra, Isla Santa Cruz, Santa Fe Island, Tortuga Bay, Otavalo, Laguna Cuicocha, Mindo, Cotopaxi National Park, Galapagos Islands, Puerto Villamil

14% OFF TODAY

Duration15 days

From

USD 4,640

USD 4,009

Saving

USD 631

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5% OFF TODAY

Cusco / Machu Picchu Tour By Train - May 2026

(1 review )

Trip customizable

Best price guaranteed

If you like to discover new cultures, customs and feel the peace of nature, this unique tour of Cusco and Machu Picchu is all you need. We hope you will join us for an experience that will change your life. Right through the day or night, Cusco is a city that is full of charms and exciting tourist attractions. The mornings are ideal for strolling Inca streets, visiting colonial churches, visiting the legendary San Blas Artisan Quarter (craftsmen) or visiting Inca villages and archaeological remains. In the evenings, the city dresses up with lights, discos, pubs and restaurants, and its main tourist attractions come alive for visitors. The nightlife in Cusco is fun, exciting and unique, and it's certainly enough to satisfy the most demanding national and foreign visitors. The city of Cusco and Machu Picchu are without a doubt experiences you will cherish all your life.

ExplorerSightseeing Tours

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, japanese, portuguese, spanish

Destinations

Cusco, Aguas Calientes, Machu Pi

Cusco, Aguas Calientes, Machu Picchu, Lima

5% OFF TODAY

Duration6 days

From

USD 810

USD 770

Saving

USD 41

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Super Sales

Galapagos & Peru Adventure - May 2026

No booking fees

Best price guaranteed

Visit South America and travel to the Galapagos Islands, Peru, Ecuador, and Bolivia. Amazing wildlife, both on land and underwater, is the drawcard of the remote Galapagos Islands. Discover unique creatures, as well as the island's outstanding natural beauty, by foot, boat and bike. Back on the mainland, enjoy the delights of Peru – from the tough but rewarding Inca Trail to the joy of interacting with friendly locals and experiencing cities full of colour, energy and passion.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Camping, Lodge, Eco Lodge, Home-stay

Age Range

15-99 yrs

Operated in

english

Destinations

Quito, La Paz, Lima, Puerto Mald

Quito, La Paz, Lima, Puerto Maldonado, Amazon Lodge Tambopata, Cusco, Ollantaytambo, Inca Trail, San Cristobal Island, Puno, Isla Isabela, Isla Santa Cruz

5% OFF TODAY

Duration24 days

From

USD 8,580

USD 8,151

Saving

USD 429

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Lares Trek & One Day Inca Trail 5 Days - May 2026

Trip customizable

Best price guaranteed

Looking for a little bit of adventure blended with culture and history? Want to trek and get out in nature but only have a short time? Our amazing Lares Trek & Short Inca Trail 5-day trip is a perfect combination of adventure, natural landscapes, vibrant culture, and rich Inca history. It even includes a tour of the famed Macchu Picchu on the last day. Start the trip from Cusco where we will drive to Pumahuanca to begin a 3-day, 2-night trek on the Lares Trail to Lares Valley. This alternative trek reveals the highlights of Peru from 600 years ago. While hiking, you will be surrounded by wild mountains, lagoons, and waterfalls and encounter indigenous people as well as llamas and alpacas in their natural habitats. Enjoy hot springs, a camping experience with your own personal cook, and stunning views. Take time to explore Ollantaytambo before hitting the Inca Trail and trekking to Machu Picchu on day 4 and then end your trip with a guided tour of Machu Picchu before we bring you back to Cusco.

Trekking and Hiking

Tour Type

Private and Group Tour

Accommodation

Camping, Hotel, Tent

Age Range

6-70 yrs

Operated in

english, spanish

Destinations

Inca Trail, Lares trek, Pumahuan

Inca Trail, Lares trek, Pumahuanca, Cuncani, Ollantaytambo, Machu Picchu, Cusco

5% OFF TODAY

Duration5 days

From

USD 850

USD 808

Saving

USD 43

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Galapagos Adventure: Northern Islands (grand Daphne) - May 2026

29% OFF TODAY

Super Sales

Galapagos Adventure: Northern Islands (Grand Daphne) - May 2026

No booking fees

Best price guaranteed

With almost 1000 kilometres of water lying between them and the South American mainland, the islands of the Galapagos were able to evolve largely undisturbed by humanity. Discover the rugged landscape of this wild place with a week-long adventure cruise, all with a local naturalist guide by your side to show you the way. Encounter sea lions, hike over hardened lava, spot diverse marine life with snorkelling opportunities and cool off in the aquamarine waters. With time to explore both on land and underwater, your adventure will show you some of the best of the northern islands – don't forget to watch the sunset from your motor yacht every night, too!

Wildlife

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

12-99 yrs

Operated in

english

Destinations

Quito, San Cristobal Island, San

Quito, San Cristobal Island, Santa Fe Island, Isla Genovesa, Isla Santiago, Isla Santa Cruz

29% OFF TODAY

Duration7 days

From

USD 4,995

USD 3,531

Saving

USD 1,464

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5% OFF TODAY

1 Day Tour of Rainbow Mountain from Cusco - May 2026

Trip customizable

Best price guaranteed

We will pick you up at 04:00 am to your hotel. After boarding your private car, we then take you to the village of Pitumarca. Pass through various towns and enjoy the incredible views of the Peruvian Andes right through the journey. Arrive your destination and start the day with a delicious breakfast. We also help you buy some provisions that are necessary during the tour. After this short stop, we will continue our journey observing the landscapes, the mysterious mountains and the deep valleys. We reach the village of Chillca at a distance of 3700 meters above sea level. From here, we start the walk uphill for 4 hours until you reach the Rainbow Mountain. When you reach the top of the mountain, you will be able to enjoy stunning views of the Andes and the Andean fauna. All the mountains surrounding this area are red and there are stunning views of the valleys and mysterious mountain of 7 colors, where we will have enough time to be able to take photos and videos. After the great experience, we will begin our return. We then proceed to enjoy a delicious lunch. After lunch, you can visit some of the locals in their homes, where you can see the way of life of people who still practice the ancient traditions of the Incas. Later we will return to Cusco at 19.00 hours.

Trekking and Hiking

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, japanese, portuguese, spanish

Destinations

Cusco

5% OFF TODAY

Duration1 day

From

USD 120

USD 114

Saving

USD 6

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34% OFF TODAY

Super Sales

Inca Encounter - May 2026

No booking fees

Best price guaranteed

Explore Peru on an eye-opening journey from the depths of the Amazon to the heights of the Andes. Get to know downtown Lima’s ornate buildings and markets, uncover Cusco’s ancient charms, encounter incredible wildlife in the Amazon, see the lush Sacred Valley and Ollantaytambo, and marvel at the wonder of Machu Picchu. Offering an up-close look at Peru's diverse attractions, this is an unforgettable trip at a relaxing pace. Discover ancient cultures, natural wonders, welcoming locals and vibrant modern life as you journey through the homeland of the Incas.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Camping, Lodge, Eco Lodge

Age Range

15-99 yrs

Operated in

english

Destinations

Inca Trail, Cusco, Lima, Puerto

Inca Trail, Cusco, Lima, Puerto Maldonado, Ollantaytambo, Machu Picchu

34% OFF TODAY

Duration10 days

5% OFF TODAY

Halloween Super Sales

Essential Peru And Bolivia - May 2026

Trip customizable

Best price guaranteed

Discover two of the top destinations in South America with this small-group tour of Peru and Bolivia! You will visit cities which are full of history, incredible architecture, and fascinating traditions. Begin your journey in Lima, the lively capital where you will find colonial attractions and modern splendors. Catch a flight to Cusco to fly over the snow-capped Andes and enjoy the breathtaking views of the mountain range. Travel through the Sacred Valley and discover fascinating ancient sites such as Chinchero and Ollantaytambo, one of the most monumental architectural complexes of the Incan Empire. Take the train to Machu Picchu and explore the Lost City of the Incas — one of the Seven Wonders of the World. Travel to Puno and enjoy the magnificent views of the valley en route. Visit Lake Titicaca, the highest navigable lake in the world, and head on a scenic hike to La Estancia as you make your way into Bolivia. Hike through Yumani and visit the Water of the Eternal Youth on the Island of the Sun, from where you will visit La Paz. Discover the incredible neighborhoods and markets of this fascinating city and take a cable car to see the gorgeous city views. Catch a flight to Uyuni to visit the largest salt flats in the world see the breathtaking sunrise. Travel back to La Paz, where you will end your tour of Peru and Bolivia filled with unforgettable memories!

Cultural, religious and historic sites

Tour Type

Group Tour

Accommodation

Hotel

Age Range

8-99 yrs

Operated in

english

Destinations

Lima, La Paz, La Paz, Sacred Val

Lima, La Paz, La Paz, Sacred Valley, Uyuni, Cusco, Puno, Lake Titicaca

5% OFF TODAY

Duration13 days

From

USD 2,624

USD 2,493

Saving

USD 131

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All South America Tours in May 2026

Page 13 of 438 Trips in South America during May 2026 with 2,087 Reviews

Page 13 of 438 Trips in South America during May 2026 with 2,087 Reviews

Mountains and Glaciers: El Calafate and Torres del Paine - May 2026

Ecuador - Andes to Amazon - May 2026

3 Day Wine & Dine Tour: Colchagua Valley - May 2026

Ushuaia & El Calafate Tour - May 2026

Simply Peru - May 2026

The Ultimate Trek to Machu Picchu: Salkantay Trek 5 Days - May 2026

Volcanoes and Galapagos - May 2026

Cusco / Machu Picchu Tour By Train - May 2026

Galapagos & Peru Adventure - May 2026

Lares Trek & One Day Inca Trail 5 Days - May 2026

Galapagos Adventure: Northern Islands (Grand Daphne) - May 2026

1 Day Tour of Rainbow Mountain from Cusco - May 2026

Inca Encounter - May 2026

Essential Peru And Bolivia - May 2026

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Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All South America Tours in May 2026

Page 13 of 438 Trips in South America during May 2026 with 2,087 Reviews

Page 13 of 438 Trips in South America during May 2026 with 2,087 Reviews