21-Day South America Tours - Unique 21-Day tours to South America

Accommodations

BudgetSimple stays with essential amenities. Typically guesthouses, hostels or hotels rated below 3 stars — clean, no-frills, and great for value-conscious travelers.
Mid-rangeComfortable and reliable 3-star stays. Expect private rooms, en-suite bathrooms, and solid amenities — a great balance between comfort and cost.
PremiumUpscale 4-5 star hotels and lodges. Enjoy high-end service, refined comfort, and premium locations — ideal for travelers seeking extra indulgence.

Absolute Peru - 21 days

(9 reviews )

No booking fees

Best price guaranteed

The 21 day adventure exceeded my expectations. It provided a wonderful introduction to the history and diversity of Peru’s culture. The hike to Machu Picchu was, in places, challenging but imminently doable. The tour leaders were knowledgeable, friendly, engaging and interesting people. My desire to participate in another G Adventures tour is driven in large part by the quality of their tour leaders.

WildlifeTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Home-stay, Guest House, Camping

Age Range

12-100 yrs

Operated in

english

Destinations

Lima, Cusco, Ollantaytambo, Agua

Lima, Cusco, Ollantaytambo, Aguas Calientes, Tambopata Reserve, Paracas, Nazca, Arequipa, Colca Canyon, Puno, Lake Titicaca

Duration21 days

View Tour

Highlights of South America - 21 days

No booking fees

Best price guaranteed

Unveil the diverse tapestry of South America on the Highlights of South America – 21 days, an easy-paced wildlife tour designed for experienced travelers and seniors. This luxurious group journey begins in Rio de Janeiro and winds through Foz Do Iguacu, La Paz, and Lima, with stops at Machu Picchu and the bustling heart of Buenos Aires. Stay in elegant hotels, visit the awe-inspiring Iguazu Falls, ascend to the world’s highest capital, and discover ancient Incan secrets. With accommodation, transport, and meals included, every detail is handled for you. The USP? A seamless, high-comfort trip through four countries, blending natural wonders, cultural treasures, and the thrill of Machu Picchu in one unforgettable package.

Wildlife

Tour Type

Group Tour

Accommodation

Hotel, Luxury Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, La Paz, Co

Rio de Janeiro, Lima, La Paz, Copacabana, Puno, Cusco, Foz Do Iguacu, Buenos Aires, Sucre

Duration21 days

View Tour

Spirit of Shackleton - 21 days

No booking fees

Best price guaranteed

Vast penguin colonies, dramatic coastlines, and the legend of Ernest Shackleton—these are just a few highlights awaiting experienced travelers on the 21-day "Spirit of Shackleton" expedition cruise. Departing from Ushuaia, this awe-inspiring photography tour sails to South Georgia, the Falkland Islands, and the Antarctic Peninsula, revealing the haunting beauty and history of the world’s most remote wilderness. Along the way, you’ll visit historic explorers’ sites and Shackleton’s final resting place, while encountering seals, penguins, and towering icebergs. The USP? This trip offers an unrivaled blend of wildlife encounters and polar history, making it a dream for those seeking a comprehensive Antarctic adventure.

Photography toursWildlife

Tour Type

Group Tour

Accommodation

Hotel, Ship Cabin

Age Range

10-100 yrs

Operated in

english

Destinations

Ushuaia, Antarctic Peninsula, Dr

Ushuaia, Antarctic Peninsula, Drake Passage, Beagle Channel Cruise, Falkland Islands, South Georgia

Duration21 days

View Tour

Galapagos Cruise & Peru’s Land of the Incas (Grand Daphne) - 21 days

No booking fees

Best price guaranteed

Begin in Quito and end in La Paz on the Galapagos Cruise & Peru’s Land of the Incas (Grand Daphne)—a 21-day odyssey across Ecuador, Peru, and Bolivia. Glide past flamingos on Isla Floreana, sunbathe with sea lions on Gardner Beach, and snorkel with turtles and rays. Then, shift gears to explore Peru’s and Bolivia’s highlands: trek through the Sacred Valley, walk the cobbled streets of Cusco, and venture into the Amazon Jungle. Enjoy a homestay on Lake Titicaca and choose to see Machu Picchu by trek or scenic train. With its challenging activity level, this tour is made for adventurous travelers who crave active, in-depth exploration. The USP is its rare combination of Galapagos island-hopping and immersive Andean and Amazonian cultural experiences, catering to those seeking variety and depth in their journey.

ExplorerCruise

Tour Type

Small Group Tour

Accommodation

Ship Cabin, Camping, Eco Lodge, Home-stay, Hotel, Lodge

Age Range

15-99 yrs

Operated in

english

Destinations

Quito, La Paz, Cusco, Ollantayta

Quito, La Paz, Cusco, Ollantaytambo, Inca Trail, Puno, Isla Santa Cruz, Floreana Island, Espanola Island, Lima, Amazon Jungle

Duration21 days

View Tour

South America 21-Day Tours and Trips

The Best 21-day Trips in South America with 9 Reviews

Absolute Peru - 21 days

Highlights of South America - 21 days

Spirit of Shackleton - 21 days

The Best 21-day Trips in South America with 9 Reviews

Galapagos Cruise & Peru’s Land of the Incas (Grand Daphne) - 21 days

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

Hi there

South America 21-Day Tours and Trips

The Best 21-day Trips in South America with 9 Reviews

Absolute Peru - 21 days

Highlights of South America - 21 days

Spirit of Shackleton - 21 days

The Best 21-day Trips in South America with 9 Reviews

Galapagos Cruise & Peru’s Land of the Incas (Grand Daphne) - 21 days