South America 21-Day Tours and Trips
Discover the best 21-Day tours in South America with Bookmundi. We offer a total of 10 South America 21-Day tours and itineraries with 20 customer reviews.
Best Price Guarantee
Best Price Guarantee
We guarantee the best prices on all our tours. If you find a lower price within 24 hours of booking, we'll match it.
Note: Prices may vary based on availability and demand.
Select from 10+ tours
10 Best South America New Year 2026 Deals for 21-Day Tours
New Year 2026 exclusive deals on 21-Day tours in South America — massive savings for a limited time only!
Craving an epic journey across South America’s most iconic landscapes? The Southern Divide tour stretches across 21 days, linking Lima with Santiago, and invites seasoned explorers to traverse Peru, Bolivia, and Chile’s most celebrated sites. This adventure winds through the Sacred Valley and legendary Machu Picchu, delves into the surreal salt flats of Uyuni and the Atacama Desert, and immerses you in the vibrant culture around Lake Titicaca. With a moderate physical activity rating, this tour is ideal for experienced travelers eager for a balance of cultural depth and scenic wonders. The trip’s unique selling point is its seamless blend of history, culture, and wilderness—thanks to the tour operator’s deep regional experience and established local offices, every logistical detail is expertly handled. You’ll have the freedom to focus on the highlights, from Andean peaks to bustling local markets, while all accommodations, meals, and transport are thoughtfully arranged.
21 days
Vast penguin colonies, dramatic coastlines, and the legend of Ernest Shackleton—these are just a few highlights awaiting experienced travelers on the 21-day "Spirit of Shackleton" expedition cruise. Departing from Ushuaia, this awe-inspiring photography tour sails to South Georgia, the Falkland Islands, and the Antarctic Peninsula, revealing the haunting beauty and history of the world’s most remote wilderness. Along the way, you’ll visit historic explorers’ sites and Shackleton’s final resting place, while encountering seals, penguins, and towering icebergs. The USP? This trip offers an unrivaled blend of wildlife encounters and polar history, making it a dream for those seeking a comprehensive Antarctic adventure.
21 days
Curious about the full spectrum of Peru’s natural wonders and ancient secrets? The "Absolute Peru" tour is crafted for adventurous, experienced travelers eager to blend challenging treks with immersive wildlife experiences. Over 21 unforgettable days, journey roundtrip from Lima through legendary sites like Nazca, Puno, Aguas Calientes, and beyond. A highlight of this trip is the iconic Inca Trail hike—demanding but richly rewarding, with panoramic vistas of cloud forests, mountain peaks, and evocative ruins awaiting those who tackle its steep paths. The fair treatment of porters and top-quality trek logistics, managed directly by the tour operator, set this tour package apart.
Beyond trekking, savor the unique opportunity to observe wildlife from the exclusive G Lodge Amazon, nestled in the lush canopy. Complementing these active days, the itinerary intersperses expertly guided excursions—such as the option to soar above the mysterious Nazca Lines—with thoughtfully allocated free time, so you can absorb Peru’s vibrant culture at your own pace. This tour is more than a sightseeing trip; it’s a deep dive into the geography, heritage, and biodiversity of Peru, tailored for those who thrive on both challenge and discovery.
21 days
Unveil the spirit of South America on this 21-day journey through Peru, Argentina, and Brazil—a region bursting with energy, color, and history. Starting in Lima and ending in Rio de Janeiro, the tour weaves through the ancient Inca heartlands, Argentina’s enigmatic cities, and the pulsating rhythms of Brazil.
You’ll marvel at Machu Picchu, stroll through vibrant markets and jungles, and experience Rio’s infectious dynamism. Along the way, local encounters and wildlife sightings offer insights into the diversity of this remarkable continent.
With an easy pace and guided exploration, the unique selling point of this trip is its comprehensive sweep across three iconic countries—inviting you to experience South America’s captivating contrasts in a single, memorable tour package.
21 days
Ready to take your sense of adventure to new altitudes? "Lima to La Paz: Sandboarding & Sunsets" is a 21-day trekking and hiking tour designed for energetic young adults who love pushing boundaries. Journey from Lima to La Paz, traversing thrilling destinations like the Nazca Lines, Colca Canyon, Aguas Calientes, and Lake Titicaca. Stand in awe of condors soaring over deep canyons, try your hand at sandboarding, and experience the warmth of a village homestay on the shores of Lake Titicaca, immersing yourself in authentic Andean culture.
This challenging trip is more than just a physical journey—it’s a cultural and scenic odyssey across Peru and Bolivia, culminating at the heights of Machu Picchu and the bustling streets of La Paz. With a perfect balance of group camaraderie and personal discovery, this tour package offers a rare combination of adventure, local interaction, and spectacular landscapes.
21 days
This voyage encompasses the best of the Antarctic Peninsula and the enchanting wildlife haven of South Georgia. Discover the historic Falklands~Malvinas and stand in awe before the world's largest king penguin colonies in South Georgia. In Antarctica, experience the serenity and grandeur of the most remote place on earth, where penguins nest, whales feed and captivating seals frolic in ice-speckled seas.
Photograph curious seals - as you Zodiac-cruise through glassy waters
Marvel at enormous king penguin colonies - in South Georgia
In the Antarctic Peninsula - whales start to arrive to feed on plentiful krill
Enjoy long days of exploration - as the peak of summer brings nearly 24 hours of daylight.
Witness bustling penguin colonies - with chicks hatching and running around
21 days
Set sail for a wildlife odyssey on "Falklands, South Georgia and Antarctica - Expedition," a 21-day relaxed cruise that traverses some of the Southern Hemisphere’s most remote and biodiverse regions. From Ushuaia, visit the penguin-filled Falkland Islands, the dramatic mountains and fjords of South Georgia, and the icy wonders of Antarctica. Encounter king penguin colonies, fur and elephant seals, and millions of seabirds. Trace Shackleton’s legacy, visit research bases, and marvel at the region’s wildflowers in spring. Accommodation, transport, and meals are included. The tour’s unique angle? The unparalleled diversity of wildlife and landscapes across three iconic destinations—ideal for nature lovers and history enthusiasts alike.
21 days
GROUP TOUR (FOR AGES 18 - 55): Set out on the ultimate South American journey with this 21 day tour, packed with bucket-list experiences, breathtaking landscapes, and thrilling adventures! Take in Medellin and Bogota, trek through the Andes to the legendary Machu Picchu, take a boat ride on Lake Titicaca, and explore the vibrant streets of La Paz. Cross the otherworldly Uyuni Salt Flats in a 4x4, marvel at flamingo-filled lagoons, and soak in high-altitude hot springs. Finally, chase adrenaline in the Atacama Desert, from cycling in the Lunar Valley to stargazing under one of the clearest night skies on Earth.
21 days
This comprehensive 3 week tour is designed to reveal some of the secrets lying in South America. The tour begins in Lima; you then head south for an incredible Ballestas Islands boat trip where you will see exotic birds and sea mammals. You then travel inland to the desert and the palm trees and sand dunes of the Oasis of Huacachina where we make camp under the stars. You will then visit the mysterious Nazca lines whose true meaning is still up for debate. The tour then starts it's ascent into the Andes to the town of Arequipa and the Colca Canyon, the deepest in the world. The tour then takes us to Cuzco where we prepare for the unforgettable Inca Trail, after reaching Machu Picchu we head back to Cuzco for some relaxing time in this beautiful Andean city. We continue our journey to Lake Titicaca where we spend time learning of the traditions of the local Uros Indians, with free time to laze the day away on the shores of this deep blue lake. The tour makes it's final stop in La Paz, giving you free time to explore the Bolivian capital.
21 days
Craving a deep dive into Peru’s wildest corners and most storied sites? The Absolute Peru: Amazon Jungle & Machu Picchu by Train tour invites experienced travelers on a thrilling 21-day adventure starting and ending in Lima. This trip is designed for those seeking both challenge and discovery, combining guided explorations with ample free time so you can absorb Peru’s dazzling diversity at your own rhythm.
Begin with an extraordinary stay at the exclusive G Lodge, nestled deep in the Amazon rainforest. Glide quietly beneath the emerald canopy, spotting exotic wildlife and soaking in the symphony of the jungle—an immersive introduction to one of the world’s greatest biodiversity hotspots. Then, shift gears to explore the dramatic landscapes that make Peru legendary: from the bustling streets of Lima and the ancient heart of Cusco, to vibrant local markets where tradition comes alive.
The journey continues as you trace the footsteps of the Incas, boarding a scenic train that winds its way through the majestic Sacred Valley to reach the iconic Machu Picchu. Marvel at this legendary archaeological wonder, perched high in the Andes, as expert guides reveal secrets of its construction and enduring mystery. For those seeking even more, optional excursions like a flight over the enigmatic Nazca Lines await, offering new perspectives on Peru’s ancient past.
This tour package uniquely blends adventure, cultural immersion, and relaxation—perfect for seasoned explorers who want to experience Peru in all its complexity. The highlight? You’ll enjoy exclusive jungle lodging and a carefully curated mix of active pursuits and downtime, ensuring your trip is as invigorating as it is rewarding. Whether you’re wandering ancient ruins, mingling with locals, or simply soaking in panoramic vistas, every day promises a new way to connect with Peru’s rich tapestry of nature and history.
21 days
See all South America 21-Day New Year 2026 Deals
Most popular South America 21-Day Tours
These popular 21-Day organized tours through South America take you across borders and cultures in one seamless multiday tour experience.
Curious about the full spectrum of Peru’s natural wonders and ancient secrets? The "Absolute Peru" tour is crafted for adventurous, experienced travelers eager to blend challenging treks with immersive wildlife experiences. Over 21 unforgettable days, journey roundtrip from Lima through legendary sites like Nazca, Puno, Aguas Calientes, and beyond. A highlight of this trip is the iconic Inca Trail hike—demanding but richly rewarding, with panoramic vistas of cloud forests, mountain peaks, and evocative ruins awaiting those who tackle its steep paths. The fair treatment of porters and top-quality trek logistics, managed directly by the tour operator, set this tour package apart.
Beyond trekking, savor the unique opportunity to observe wildlife from the exclusive G Lodge Amazon, nestled in the lush canopy. Complementing these active days, the itinerary intersperses expertly guided excursions—such as the option to soar above the mysterious Nazca Lines—with thoughtfully allocated free time, so you can absorb Peru’s vibrant culture at your own pace. This tour is more than a sightseeing trip; it’s a deep dive into the geography, heritage, and biodiversity of Peru, tailored for those who thrive on both challenge and discovery.
Duration
21 Days
Price per day
USD 143
Tour Type
Group Tour
21 days
Ready to take your sense of adventure to new altitudes? "Lima to La Paz: Sandboarding & Sunsets" is a 21-day trekking and hiking tour designed for energetic young adults who love pushing boundaries. Journey from Lima to La Paz, traversing thrilling destinations like the Nazca Lines, Colca Canyon, Aguas Calientes, and Lake Titicaca. Stand in awe of condors soaring over deep canyons, try your hand at sandboarding, and experience the warmth of a village homestay on the shores of Lake Titicaca, immersing yourself in authentic Andean culture.
This challenging trip is more than just a physical journey—it’s a cultural and scenic odyssey across Peru and Bolivia, culminating at the heights of Machu Picchu and the bustling streets of La Paz. With a perfect balance of group camaraderie and personal discovery, this tour package offers a rare combination of adventure, local interaction, and spectacular landscapes.
Duration
21 Days
Price per day
USD 113
Tour Type
Group Tour
21 days
Craving an epic journey across South America’s most iconic landscapes? The Southern Divide tour stretches across 21 days, linking Lima with Santiago, and invites seasoned explorers to traverse Peru, Bolivia, and Chile’s most celebrated sites. This adventure winds through the Sacred Valley and legendary Machu Picchu, delves into the surreal salt flats of Uyuni and the Atacama Desert, and immerses you in the vibrant culture around Lake Titicaca. With a moderate physical activity rating, this tour is ideal for experienced travelers eager for a balance of cultural depth and scenic wonders. The trip’s unique selling point is its seamless blend of history, culture, and wilderness—thanks to the tour operator’s deep regional experience and established local offices, every logistical detail is expertly handled. You’ll have the freedom to focus on the highlights, from Andean peaks to bustling local markets, while all accommodations, meals, and transport are thoughtfully arranged.
Duration
21 Days
Price per day
USD 150
Tour Type
Group Tour
21 days
Set sail for a wildlife odyssey on "Falklands, South Georgia and Antarctica - Expedition," a 21-day relaxed cruise that traverses some of the Southern Hemisphere’s most remote and biodiverse regions. From Ushuaia, visit the penguin-filled Falkland Islands, the dramatic mountains and fjords of South Georgia, and the icy wonders of Antarctica. Encounter king penguin colonies, fur and elephant seals, and millions of seabirds. Trace Shackleton’s legacy, visit research bases, and marvel at the region’s wildflowers in spring. Accommodation, transport, and meals are included. The tour’s unique angle? The unparalleled diversity of wildlife and landscapes across three iconic destinations—ideal for nature lovers and history enthusiasts alike.
Duration
21 Days
Price per day
USD 955
Tour Type
Group Tour
21 days
This voyage encompasses the best of the Antarctic Peninsula and the enchanting wildlife haven of South Georgia. Discover the historic Falklands~Malvinas and stand in awe before the world's largest king penguin colonies in South Georgia. In Antarctica, experience the serenity and grandeur of the most remote place on earth, where penguins nest, whales feed and captivating seals frolic in ice-speckled seas.
Photograph curious seals - as you Zodiac-cruise through glassy waters
Marvel at enormous king penguin colonies - in South Georgia
In the Antarctic Peninsula - whales start to arrive to feed on plentiful krill
Enjoy long days of exploration - as the peak of summer brings nearly 24 hours of daylight.
Witness bustling penguin colonies - with chicks hatching and running around
Duration
21 Days
Price per day
USD 1,503
Tour Type
Group Tour
21 days
Unveil the spirit of South America on this 21-day journey through Peru, Argentina, and Brazil—a region bursting with energy, color, and history. Starting in Lima and ending in Rio de Janeiro, the tour weaves through the ancient Inca heartlands, Argentina’s enigmatic cities, and the pulsating rhythms of Brazil.
You’ll marvel at Machu Picchu, stroll through vibrant markets and jungles, and experience Rio’s infectious dynamism. Along the way, local encounters and wildlife sightings offer insights into the diversity of this remarkable continent.
With an easy pace and guided exploration, the unique selling point of this trip is its comprehensive sweep across three iconic countries—inviting you to experience South America’s captivating contrasts in a single, memorable tour package.
Duration
21 Days
Price per day
USD 482
Tour Type
Group Tour
21 days
Craving a deep dive into Peru’s wildest corners and most storied sites? The Absolute Peru: Amazon Jungle & Machu Picchu by Train tour invites experienced travelers on a thrilling 21-day adventure starting and ending in Lima. This trip is designed for those seeking both challenge and discovery, combining guided explorations with ample free time so you can absorb Peru’s dazzling diversity at your own rhythm.
Begin with an extraordinary stay at the exclusive G Lodge, nestled deep in the Amazon rainforest. Glide quietly beneath the emerald canopy, spotting exotic wildlife and soaking in the symphony of the jungle—an immersive introduction to one of the world’s greatest biodiversity hotspots. Then, shift gears to explore the dramatic landscapes that make Peru legendary: from the bustling streets of Lima and the ancient heart of Cusco, to vibrant local markets where tradition comes alive.
The journey continues as you trace the footsteps of the Incas, boarding a scenic train that winds its way through the majestic Sacred Valley to reach the iconic Machu Picchu. Marvel at this legendary archaeological wonder, perched high in the Andes, as expert guides reveal secrets of its construction and enduring mystery. For those seeking even more, optional excursions like a flight over the enigmatic Nazca Lines await, offering new perspectives on Peru’s ancient past.
This tour package uniquely blends adventure, cultural immersion, and relaxation—perfect for seasoned explorers who want to experience Peru in all its complexity. The highlight? You’ll enjoy exclusive jungle lodging and a carefully curated mix of active pursuits and downtime, ensuring your trip is as invigorating as it is rewarding. Whether you’re wandering ancient ruins, mingling with locals, or simply soaking in panoramic vistas, every day promises a new way to connect with Peru’s rich tapestry of nature and history.
Duration
21 Days
Price per day
USD 142
Tour Type
Group Tour
21 days
If you're seeking an immersive trekking adventure through the heart of Peru and Bolivia, the "Peru Essentials" tour delivers a 21-day journey packed with cultural intrigue and breathtaking landscapes. Setting out from Lima, this challenging trip is perfectly suited for active travelers ready to hike ancient trade routes, including the iconic Inca Trail, culminating at the legendary Machu Picchu. Along the way, you’ll marvel at the soaring condors of Colca Canyon, explore the mysterious Nazca lines, and soak up local traditions on Lake Titicaca’s floating islands. The tour also ventures into Bolivia, concluding in La Paz, giving you a rare opportunity to experience two vibrant countries in one seamless package. With guidance from a knowledgeable local leader, plus plenty of flexibility to personalize your itinerary, this tour package stands out for its expertly balanced blend of guided exploration and independence—making it ideal for those who crave both structure and adventure. Accommodation, transport, and meals are all provided, so you can focus on trekking, hiking, and soaking in the diverse wonders of South America.
Duration
21 Days
Price per day
USD 151
Tour Type
Group Tour
21 days
Begin in Quito and end in La Paz on the Galapagos Cruise & Peru’s Land of the Incas (Grand Daphne)—a 21-day odyssey across Ecuador, Peru, and Bolivia. Glide past flamingos on Isla Floreana, sunbathe with sea lions on Gardner Beach, and snorkel with turtles and rays. Then, shift gears to explore Peru’s and Bolivia’s highlands: trek through the Sacred Valley, walk the cobbled streets of Cusco, and venture into the Amazon Jungle. Enjoy a homestay on Lake Titicaca and choose to see Machu Picchu by trek or scenic train. With its challenging activity level, this tour is made for adventurous travelers who crave active, in-depth exploration. The USP is its rare combination of Galapagos island-hopping and immersive Andean and Amazonian cultural experiences, catering to those seeking variety and depth in their journey.
Duration
21 Days
Price per day
USD 410
Tour Type
Group Tour
21 days
Explore South America's salt flats, ancient deserts, geysers and valleys on this 21-day adventure from Lima to San Pedro De Atacama. Ride the teleferico (cable car) over the world’s tallest capital city (La Paz), explore the Andrean Desert and travel across the Uyuni Salt Flats with a local leader by your side. Learn about ancient rock carvings at Yerbas Buenas, discover the diverse ecology in the depths of the Amazon and journey around the islands of Lake Titicaca. See flamingo-filled lagoons and lunar valleys as you cross into the Atacama Desert, watch the sun rise over Rainbow Canyon and indulge in Bolivian and Chilean cuisine every step of the way.
Duration
21 Days
Price per day
USD 395
Tour Type
Group Tour
21 days
See all South America 21-Day Tours
Top Tour Activities for 21-Day South America Tours
Explore 21-Day South America multiday tours that match your travel style through-out South America—whether it's explorer tours, cultural, religious and historic sites trips, or another trip activity. Your continental experience awaits.
South America Tour Reviews
Genuine reviews from travelers on 21-Day South America tours
Berta | Traveled in March
We have just returned from our trip to Argentina and Chile Patagonia. The whole trip was amazing. We especially enjoyed Northern Argentina and the High Andes. Victoria did an amazing job with the itinerary. She was very patient, responding to many emails and questions. All our services and transfers were spot on. Edgar, our guide and driver in Northern Argentina, Salta, and the Andes, was great. Many thanks to Victoria for organizing the perfect trip!
Elisabeth W | Traveled in January
Exceptional tour with the perfect pace to acclimate to the high altitude. Every other day felt like a highlight - there is so much more than Macchu Picchu and the Salt flats. Our CEO Elier was the best guide you could wish for - funny, helpful and always in a good mood.
stuart during | Traveled in March
The trip was excellent and covered a huge amount of Argentina and Uruguay. Guides were all attentive and knowledgeable , several with limited English but tried their best, nevertheless. Hotel accommodations were adequate: three-star or less.
Anonymous | Traveled in November
Fantastic trip. Great excursions and sights. Lots of effort to get us out and ashore. Great communication. Great accommodation. Loved the yoga. THANK YOU ALL SO MUCH. I AM SOOO HAPPY!!!
Simon J | Traveled in July
Overlanding may not be for everyone as it is very much a shared travelling experience. This was our second trip with Dragoman after hopping off the truck in Santiago and travelling independently for a couple of months before re-joining the same truck in Lima. As before, we very much enjoyed the whole journey and also the wonderful crew and fellow travellers, who are all now active personal friends on social media well after the trip.
Anonymous | Traveled in September
As described, the itinerary encompasses a tremendous range of activities, venues and experiences which provided insights into the country's culture, history and heritage. We met many interesting people along the way and had great fun with fellow travellers and guides. As usual with Exodus trips there were many early mornings and some long journeys, but these are necessary for the trip to achieve the stated aims! Hotels were comfortable and all had suitable amenities. Food - and drink - was plentiful and tasty and generally good quality. The route was well planned and enabled us to fully acclimatise before attempting the focal activity for us - the Inca Trail. It also put the trail and Machu Picchu into a broader context so that we appreciated it all even more. Support on the Inca Trail, from our guide and 'porters' was exceptional. We had a great time and thoroughly enjoyed (almost) every minute.
Keep Exploring South America
Tour Types
- South America Tours
- South America Eco Tours
- South America Guided and Escorted Tours
- South America Group Tours
- South America Small Group Tours
- South America Tailor-made Vacation Packages
- South America Travel Deals
- South America Experienced Travelers Trips
- South America Solo Trips
- South America Budget Tours
- South America Tours for Young Adults
- South America Tours for Senior Citizens
- South America Private Tours
- South America Last Minute Deals
- South America Self Guided Tours
- South America Luxury Tours
- South America Tour Operators
Popular Destinations
Popular Activities
- Explorer Tours
- Trekking and Hiking Tours
- Cultural, religious and historic sites Tours
- Adventure Tours
- Natural landmarks sightseeing Tours
- City sightseeing Tours
- Wildlife Tours
- Active and outdoor Tours
- National parks Tours
- Wildlife safaris and game drives Tours
- Beach Tours
- Art and architecture Tours
- Sightseeing Tours
- Rainforest and jungle visits Tours
- Walking Tours
- Bicycle Tours