10 Best Panama City Multiday Tours in October 2025

San Blas Chichime Islands Experience 4D/3N - October 2025

No booking fees

Best price guaranteed

Escape to a tropical paradise with an unforgettable adventure in the San Blas Chichime Islands. Revel in pristine beaches, crystal-clear waters, and vibrant marine life. Snorkel around coral reefs, interact with the indigenous Guna Yala community, and savor mouthwatering seafood. Enjoy the rustic charm of island cabins amidst swaying palms. Ideal for travelers seeking relaxation and exploration, this experience offers the perfect blend of cultural immersion and natural beauty. Discover why the San Blas Islands are a top bucket-list destination.

AdventureExplorer

Tour Type

Small Group Tour

Accommodation

Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City, San Blas Islands

Duration4 days

From

USD 575

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San Jose to Panama City Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Costa Rica's vibrant San Jose to Panama City's cultural heart. Experience thrilling zip-lining in Monteverde, discover Arenal's majestic volcano, soak in thermal hot springs, and relax on Bocas del Toro's pristine beaches. Journey through dense jungles, explore indigenous villages, and marvel at the striking Panama Canal. This travel pass offers a seamless blend of natural wonders, adrenaline-pumping activities, and rich cultural encounters, making it perfect for adventurous travelers seeking an immersive Central American odyssey.

Sightseeing ToursExplorer

Tour Type

Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City, San Jose, Puerto Vi

Panama City, San Jose, Puerto Viejo de Talamanca, Bocas Del Toro, San Blas Islands

Duration7 days

From

USD 877

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Panama City to San Jose Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable journey from Panama City to San Jose with Bamba travel. Experience the best of Central America, exploring lush rainforests, pristine beaches, and vibrant local cultures. Highlights include island-hopping in Bocas del Toro, thrilling zip-lining in the Costa Rican canopy, and immersing yourself in indigenous traditions. Perfect for adventure seekers, this tour promises unique cultural encounters and breathtaking natural beauty, ensuring an exhilarating and diverse travel experience you won't forget. Book now for the ultimate Central American adventure!

National parks

Tour Type

Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City, San Jose, La Fortun

Panama City, San Jose, La Fortuna, San Blas Islands, Bocas Del Toro, Puerto Viejo de Talamanca

Duration10 days

From

USD 1,549

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Panama City to Bogota Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Panama City to Bogota, immersing yourself in vibrant cultures, lush landscapes, and rich histories. This seamless travel pass offers unique experiences, including exploring Panama Canal’s marvels, snorkeling in San Blas Islands’ crystal waters, discovering Medellín's urban transformation, and delving into Bogota’s dynamic arts scene. Perfect for thrill-seekers and culture enthusiasts, this tour promises a diverse blend of activities, ensuring an enriching journey through Central America's hidden gems and Colombia's enchanting urban hubs.

BeachSnorkelingExplorer

Tour Type

Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Bogota, Panama City, San Blas Is

Bogota, Panama City, San Blas Islands, Medellin, Manizales, Hacienda Venecia Coffe Farm

Duration10 days

From

USD 1,629

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Welcome to Panama City 4D/3N - October 2025

No booking fees

Best price guaranteed

Uncover the mystique of Panama City over four captivating days, where vibrant cultures intertwine with the timeless remnants of Casco Viejo. Traverse the enchanting streets and immerse yourself in the living history, intriguing architecture, and bustling local life that define this dynamic region. Each day unveils a new chapter of exploration, inviting you into the heart of Panama's most storied locales.

Explorer

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City

Duration4 days

From

USD 302

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Welcome to Panama City 3D/2N - October 2025

No booking fees

Best price guaranteed

Embark on a captivating journey through Panama City, uniting the thrilling energy of the local culture with the historic charm of Casco Viejo. From the moment you arrive, immerse yourself in the tales of ancient streets, the beauty of striking architecture, and the stories of the past that shape today. This three-day jaunt promises a delightful blend of exploration, discovery, and leisure, enveloped within breathtaking sights and vibrant histories.

Explorer

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City

Duration3 days

From

USD 213

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Discover the Unseen Panama 13D/12N - October 2025

No booking fees

Best price guaranteed

Discover the mesmerizing fusion of vibrant city life and tranquil coastal paradises in Panama. Journey through historical sites, breathtaking beaches, and rich biodiversity, while uncovering the diverse cultural tapestry of this captivating nation. From Panama City's urban allure to Bocas del Toro's eco-escapades, every day offers a unique adventure amidst stunning landscapes and vibrant culture.

Explorer

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City, Bocas Del Toro, Pla

Panama City, Bocas Del Toro, Playa Venao, Santa Catalina, Boquete

Duration13 days

From

USD 2,038

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Antigua to Panama City Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable Central America adventure with Bamba’s travel pass taking you from Antigua to Panama City. This immersive journey offers diverse experiences including exploring ancient Mayan ruins, soaking up the sun on pristine beaches, and hiking lush rainforests. Thrill-seekers can revel in adrenaline-pumping activities like volcano treks and zip-lining. Discover vibrant cultures, delicious cuisine, and captivating landscapes. Ideal for solo travelers and groups alike, this adventure ensures a seamless and memorable travel experience across stunning destinations.

Explorer

Tour Type

Group Tour

Accommodation

Home-stay, Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City, Antigua, Panajachel

Panama City, Antigua, Panajachel, El Tunco, Leon, Granada, San Jorge, Ometepe, San Juan Del Sur, Liberia City, San Jorge La Laguna, Monteverde, Manuel Antonio, San Jose, Tortuguero, Puerto Viejo de Talamanca, Bocas Del Toro, San Blas Islands, Lanquin, Copán Ruinas

Duration35 days

From

USD 3,471

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San Blas Cayos Holandeses Adventure 3D/2N - October 2025

No booking fees

Best price guaranteed

Embark on a captivating San Blas adventure in the pristine Cayos Holandeses, a hidden gem in Panama. Enjoy snorkeling in crystal-clear waters, exploring remote islands, and immersing in the rich Kuna culture. Discover exotic marine life, serene beaches, and stunning sunsets that will leave you breathless. Ideal for eco-travelers and adventure seekers, this trip offers an unforgettable mix of relaxation and exploration. Book now and experience the ultimate island escape in the heart of Panama's Caribbean paradise!

AdventureExplorer

Tour Type

Small Group Tour

Accommodation

Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City, San Blas Islands

Duration3 days

From

USD 583

View Tour

All Panama City Tours in October 2025

9 Trips in Panama City during October 2025

San Blas Chichime Islands Experience 4D/3N - October 2025

San Jose to Panama City Travel Pass - October 2025

Panama City to San Jose Travel Pass - October 2025

Panama City to Bogota Travel Pass - October 2025

Welcome to Panama City 4D/3N - October 2025

Welcome to Panama City 3D/2N - October 2025

Discover the Unseen Panama 13D/12N - October 2025

Antigua to Panama City Travel Pass - October 2025

San Blas Cayos Holandeses Adventure 3D/2N - October 2025

9 Trips in Panama City during October 2025

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All Panama City Tours in October 2025

9 Trips in Panama City during October 2025

9 Trips in Panama City during October 2025