10 Best Andes Multiday Tours in September 2025

La Paz to Santiago Travel Pass - September 2025

No booking fees

Best price guaranteed

Discover an unforgettable adventure from La Paz to Santiago, exploring the heart of South America with unparalleled experiences. Traverse Bolivia, Peru, and Chile, diving into the vibrant cultures of each destination. This travel pass immerses you in unique activities like gazing at the Uyuni Salt Flats, exploring the Atacama Desert, and vibrant city vibes. Perfect for backpackers and culture enthusiasts seeking an authentic journey, this tour promises unforgettable memories and breathtaking landscapes. Book now for an epic South American odyssey!

Active and outdoorVolcanoes

Tour Type

Group Tour

Accommodation

Hotel, Hostel, Lodge, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, La Paz, San Pedro De A

Santiago, La Paz, San Pedro De Atacama, La Serena, Valparaiso, Sucre, Potosi, Uyuni, Agencha, Polques

Duration17 days

From

USD 1,257

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Santiago to Ushuaia (Ruta 40) Travel Pass - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable Patagonia adventure with Bamba’s epic journey from Santiago to Ushuaia. Traverse the legendary Ruta 40, experiencing breathtaking landscapes, majestic glaciers, and lush national parks. Hike in Torres del Paine, explore the vibrant streets of Buenos Aires, and witness the awe-inspiring Perito Moreno Glacier. This expertly curated tour offers immersive cultural experiences and unparalleled natural beauty, making it perfect for adventurous travelers seeking the ultimate South American expedition. Book now for an extraordinary travel experience.

Active and outdoorAdventure

Tour Type

Group Tour

Accommodation

Hotel, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Ushuaia, El Chalten, E

Santiago, Ushuaia, El Chalten, El Calafate, Pucon, Puerto Varas, San Carlos de Bariloche, Perito Moreno Glacier

Duration14 days

From

USD 1,562

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Salta to La Paz Salt Flats Adventure 10D/9N - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from the vibrant culture of Salta to the mesmerizing Uyuni Salt Flats in Bolivia. This 10-day experience offers unique encounters with breathtaking Andean landscapes, ancient ruins, and indigenous villages. Highlights include traversing the awe-inspiring altiplano, marveling at surreal salt deserts, and exploring colorful lagoons teeming with flamingos. Perfect for thrill-seekers and culture enthusiasts, this tour promises an extraordinary blend of nature, history, and adventure for an unmatched South American escape.

AdventureWalking tours

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Salta, La Paz, San Pedro

La Paz, Salta, La Paz, San Pedro De Atacama, Uyuni

Duration10 days

From

USD 3,440

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Rio de Janeiro to Buenos Aires (via Iguazu) Travel Pass - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from the vibrant streets of Rio de Janeiro to the cultural heart of Buenos Aires, seamlessly connecting you through the awe-inspiring Iguazu Falls. This immersive travel pass offers unique experiences like exploring Brazil's iconic Christ the Redeemer, hiking the lush rainforest, and reveling in Argentina's vibrant tango scene. Perfect for wanderlust-driven explorers, this journey promises unparalleled natural beauty, cultural richness, and thrilling activities, ensuring memories that last a lifetime. Discover South America's best-kept secrets today!

AdventureActive and outdoor

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Pu

Buenos Aires, Rio de Janeiro, Puerto Iguazu, Ilha Grande, Paraty, Sao Paulo, Foz Do Iguacu

Duration12 days

From

USD 1,172

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Ushuaia to Santiago (Ruta 40) Travel Pass - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable Patagonian adventure from snow-capped Ushuaia to vibrant Santiago along iconic Ruta 40. Discover pristine landscapes, immersive cultural encounters, and thrilling outdoor activities. Highlights include exploring the picturesque Glacier National Park, hiking in stunning El Chaltén, and marveling at the surreal Atacama Desert. Dive into local Argentine and Chilean traditions while indulging in exceptional gastronomy. Experience the ultimate South American journey with diverse terrains, breathtaking vistas, and memorable moments tailored for adventurous travelers.

Active and outdoor

Tour Type

Group Tour

Accommodation

Hotel, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Ushuaia, Pucon, El Cal

Santiago, Ushuaia, Pucon, El Calafate, El Chalten, Perito Moreno Glacier, San Carlos de Bariloche, Puerto Varas

Duration12 days

From

USD 1,394

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14 Day Trip: Galapagos & Machu Picchu - September 2025

Trip customizable

Best price guaranteed

On this 14-day guided tour trip, you will visit the highlights of both Ecuador and Peru. Experience the highlights of the City of Quito, Cotopaxi National Park, the Galapagos Islands: Santa Cruz, El Chato, Charles Darwin Station, Pinzon Island / Isabela Island, Tintoreras, and Cabo Rosa Tunnels. In Peru, you will have the opportunity to get to know the highlights of the ancient Inca civilization. Explore the city of Cusco, the Sacred Valley, the mountain of colors, and Machu Picchu. Visit Inca structures, and learn about the historic Inca settlements and their history. You will be accompanied by a guide, who will assist you with anything you need. We will also provide you with transportation, accommodation and some meals.

Trekking and HikingWildlife

Tour Type

Group Tour

Accommodation

Hotel

Age Range

5-80 yrs

Operated in

english, spanish

Destinations

Cusco, Machu Picchu, Quito, Lima

Cusco, Machu Picchu, Quito, Lima, Galapagos Islands, Santa Cruz, Sacred Valley, Cotopaxi National Park, Mitad Del Mundo, Isla Isabela, Los Túneles

Duration14 days

From

USD 3,995

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Buenos Aires to Rio de Janeiro (via Iguazu & Florianopolis) Travel Pass - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from vibrant Buenos Aires to picturesque Rio de Janeiro, traversing breathtaking Iguazu Falls and stunning Florianopolis. This immersive journey offers unique experiences like exploring Argentina's bustling capital, marveling at the thundering Iguazu Falls, and soaking up Florianopolis' beautiful beaches. End your tour with the iconic sights of Rio, including Christ the Redeemer and Copacabana Beach. This South American escapade combines urban excitement, natural wonders, and coastal relaxation, promising an enriching travel experience.

City sightseeingWaterfalls

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Sa

Buenos Aires, Rio de Janeiro, Sao Paulo, Paraty, Ilha Grande, Puerto Iguazu, Florianopolis, Curitiba

Duration15 days

From

USD 1,173

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Santiago to Buenos Aires (via Mendoza) Travel Pass - September 2025

No booking fees

Best price guaranteed

Discover an unforgettable adventure from Santiago to Buenos Aires, immersing yourself in the rich culture and breathtaking landscapes of South America. Journey through the scenic Andes, savor exquisite wines in Mendoza, and experience vibrant city life in Buenos Aires. This curated travel pass offers guided tours, diverse outdoor activities, and authentic local experiences. Perfect for wine enthusiasts and adventure seekers, this tour offers the ultimate blend of nature, culture, and culinary delights. Book now for an extraordinary South American escapade!

Adventure

Tour Type

Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Mendoza

Buenos Aires, Santiago, Mendoza, Córdoba

Duration7 days

From

USD 505

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Buenos Aires to Rio de Janeiro (via Iguazu) Travel Pass - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Buenos Aires to Rio de Janeiro via the natural marvels of Iguazu with Bamba travel. Experience vibrant tango nights, awe-inspiring Iguazu Falls, and the lively rhythm of Rio's Copacabana. Delight in cultural immersion, exquisite cuisine, and iconic landmarks as you traverse Argentina and Brazil. This travel pass promises unique experiences, from bustling city life to breathtaking natural wonders, perfect for adventurous explorers seeking the ultimate South American journey.

BeachWaterfalls

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Pa

Buenos Aires, Rio de Janeiro, Paraty, Ilha Grande, Puerto Iguazu, Foz Do Iguacu, Sao Paulo

Duration14 days

From

USD 1,116

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Rio de Janeiro to Buenos Aires (via Uruguay) Travel Pass - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Rio de Janeiro to Buenos Aires, exploring the vibrant cultures of Brazil, Uruguay, and Argentina. Discover Rio's iconic beaches, Uruguay’s charming colonial towns, and Argentina’s bustling capital. Immerse yourself in breathtaking scenery, diverse culinary delights, and rich histories. Highlights include Christ the Redeemer, Montevideo’s lively markets, and Buenos Aires’ famous tango shows. This travel pass promises an immersive South American experience, offering a perfect blend of city life, natural beauty, and authentic local encounters.

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Po

Buenos Aires, Rio de Janeiro, Porto Alegre, Punta Del Este, Montevideo, Colonia Del Sacramento, Ilha Grande, Paraty, Sao Paulo, Florianopolis

Duration18 days

From

USD 2,097

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Buenos Aires to Rio de Janeiro (via Uruguay) Travel Pass - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Buenos Aires to Rio de Janeiro, journeying through the captivating landscapes of Uruguay. Discover vibrant cultures, stunning beaches, and iconic landmarks. Highlights include exploring Buenos Aires’ tango-filled streets, soaking in Montevideo’s rich history, and relaxing in Punta del Este’s luxurious resorts. End your trip basking in Rio’s energetic vibe and iconic Christ the Redeemer statue. Perfect for travelers seeking diverse experiences, this South American expedition promises breathtaking sights and unparalleled memories.

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hotel, Resort

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Sa

Buenos Aires, Rio de Janeiro, Sao Paulo, Paraty, Ilha Grande, Colonia, Montevideo, Punta Del Este, Florianopolis

Duration16 days

From

USD 1,372

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Buenos Aires to Santiago (via Mendoza) Travel Pass - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable journey from Buenos Aires to Santiago, immersing yourself in local culture and breathtaking landscapes. Enjoy wine tasting in Argentina's famed Mendoza region, marvel at the Andes’ majestic beauty, and discover vibrant cities bursting with history, art, and gastronomy. Perfect for adventure seekers and culture enthusiasts, this travel pass offers a seamless blend of city life and scenic wonders. Don't miss this chance to explore South America's most dynamic destinations.

Explorer

Tour Type

Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Córdoba

Buenos Aires, Santiago, Córdoba, Mendoza

Duration7 days

From

USD 540

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Samba & Tango Air-Expedition 14D/13N (from Buenos Aires) - September 2025

No booking fees

Best price guaranteed

Embark on an exhilarating South American adventure with an exclusive air-expedition that takes you from Buenos Aires to the heart of Brazil and Argentina. Experience the vibrant cultures of Samba and Tango as you explore iconic landmarks, indulge in local cuisines, and immerse yourself in rich traditions. Highlights include scenic helicopter flights over Iguazu Falls, guided tours of Rio de Janeiro, and captivating dance performances. Perfect for culture enthusiasts and thrill-seekers, this journey guarantees unforgettable memories.

AdventureWalking tours

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Il

Buenos Aires, Rio de Janeiro, Ilha Grande, Puerto Iguazu, Foz Do Iguacu, Paraty

Duration14 days

From

USD 5,647

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Uyuni Salt Flats & Desert Adventure 4D/3N (Atacama to Atacama) - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable journey from the Atacama Desert to Bolivia’s Uyuni Salt Flats, renowned as the world's largest salt flat. This adventure includes stunning landscapes, geothermal wonders, and vibrant lagoons brimming with flamingos. Travel through surreal rock formations and pristine deserts, capturing breathtaking sunset reflections on the salt flats. Ideal for nature enthusiasts and photographers, this expedition offers an immersive experience in one of South America’s most iconic and picturesque regions. Join this extraordinary tour today!

Desert safaris

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Uyuni, San Pedro De Atacama, Lag

Uyuni, San Pedro De Atacama, Laguna Colorada, Chiguana Salt Flat, Villamar Mallcu

Duration4 days

From

USD 414

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All Andes Tours in September 2025

Page 2 of 217 Trips in Andes during September 2025 with 277 Reviews

La Paz to Santiago Travel Pass - September 2025

Santiago to Ushuaia (Ruta 40) Travel Pass - September 2025

Salta to La Paz Salt Flats Adventure 10D/9N - September 2025

Rio de Janeiro to Buenos Aires (via Iguazu) Travel Pass - September 2025

Ushuaia to Santiago (Ruta 40) Travel Pass - September 2025

14 Day Trip: Galapagos & Machu Picchu - September 2025

Buenos Aires to Rio de Janeiro (via Iguazu & Florianopolis) Travel Pass - September 2025

Santiago to Buenos Aires (via Mendoza) Travel Pass - September 2025

Buenos Aires to Rio de Janeiro (via Iguazu) Travel Pass - September 2025

Rio de Janeiro to Buenos Aires (via Uruguay) Travel Pass - September 2025

Buenos Aires to Rio de Janeiro (via Uruguay) Travel Pass - September 2025

Buenos Aires to Santiago (via Mendoza) Travel Pass - September 2025

Samba & Tango Air-Expedition 14D/13N (from Buenos Aires) - September 2025

Uyuni Salt Flats & Desert Adventure 4D/3N (Atacama to Atacama) - September 2025

Page 2 of 217 Trips in Andes during September 2025 with 277 Reviews

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North America

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Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Andes Tours in September 2025

Page 2 of 217 Trips in Andes during September 2025 with 277 Reviews

Page 2 of 217 Trips in Andes during September 2025 with 277 Reviews