Santiago and Buenos Aires are two major nerve centers of South America that you can explore in a single vacation. From the majestic Andes Mountains to the sweeping plains of the Pampas, a trip from Santiago to Buenos Aires promises a mesmerizing tapestry of scenery and experiences. Whether by air, bus, or car, adventurers can easily navigate the distance, immersing themselves in the rich history, tantalizing cuisine, and vibrant rhythms that define these vibrant cities.
Ways to Get to Buenos Aires from Santiago
When planning a trip from Buenos Aires to Santiago, you have several options, from direct flights connecting the bustling capital cities to overnight buses and rental cars.
By flight
Flights are the most comfortable means of transportation, but they are also the most expensive.
Flying from Santiago to Buenos Aires is the most comfortable and quickest way to travel between the two cities. Several airlines, including Sky Airline, LATAM Chile, and Jetsmart, operate direct flights. Airfare can range from USD 86 to USD 499. Flights departing from Santiago International Airport (SCL) to Ezeiza International Airport (EZE) take approximately 2 hours to complete. The distance between these two airports is around 1141 km. Once you land at Ezeiza International Airport, you can get a private transfer to reach Buenos Aires city center, which takes about 1 hour. If you take a bus, the journey will take around 2 hours. Flights to Aeroparque Internacional Jorge Newbery (AEP), which is closer to the city center, are also available, but they may involve more extended layovers and overall longer travel duration.
Distance covered: Approximately 1,141 kilometers
Duration of direct flight: Around 2 hours (4 hours with layovers)
Pro tips:
Santiago to Buenos Aires flights frequently sell out, particularly during the busiest travel times. So book in advance to secure better rites and seats.
Some flights may have layovers, especially if you opt for cheaper fares. Consider how long layovers will last and whether a direct ticket is worth the extra money.
Baggage allowances and costs can vary from airline to airline. So be sure to read the airline's luggage policies.
Use websites like Skyscanner or Kayak to compare prices and in-flight services to find the best option.
Plan various ways to get from the airport to the city center. Depending on your preferences and financial situation, you can use public transit, taxis, or private shuttles.
By bus
Experience the diverse landscapes from Santiago to Buenos Aires with a scenic bus ride, where every mile promises a new adventure through the majestic Andes and sweeping plains of Argentina.
Traveling by bus from Santiago to Buenos Aires is a great way to experience the amazing scenery along your journey. There is a direct bus that leaves from Los Heroes terminal in Santiago to Terminal de Omnibus Retiro in Buenos Aires on Mondays and Fridays. Spanning approximately 1,171 km, the bus journey typically lasts between 22 to 24 hours, depending on the chosen route. Ticket prices range from USD 45 to USD 65. Several reputable bus companies operate the routes between Santiago and Buenos Aires, offering multiple comfort levels and services. Companies like Andesmar and CATA Internacional are popular choices.
Distance covered: Approximately 1,171 kilometers
Duration: Between 22 to 24 hours, depending on the chosen route.
Pro tips:
Look up and read reviews of various bus companies that travel from Buenos Aires to Santiago, and opt for reputable ones.
Bus schedules may vary, so check departure dates and times to align with your travel plans.
To secure a good seat and possibly grab a better deal, purchase your tickets well in advance.
Prioritize your comfort for the long bus journey by selecting a reclining seat or a seat with extra legroom.
Be prepared for border crossing procedures, including passport checks and customs inspections. To speed up the process, make sure all required documents are easily accessible.
Always keep your valuables visible and safe, especially when traveling and stopping for breaks. Think about packing essentials in a carry-on bag or using a money belt.
By car
Embrace freedom and adventure on a road trip from Santiago to Buenos Aires, where you set the pace and discover new experiences at every turn
Taking a road trip from Santiago to Buenos Aires offers you the freedom to explore and travel at your own pace. Along the way, you can also discover several hidden gems. The trip covers a distance of about 1,400 kilometers, and usually takes 16 to 17 hours to complete. You can choose between routes that traverse the majestic Andes Mountains via Paso Los Libertadores or the scenic highway through Mendoza's renowned wineries and mountain vistas. The cost of renting a car from Santiago to Buenos Aires ranges from USD 170 to USD 250 per day. You must also account for other expenses such as fuel and highway tolls.
Distance covered: Approximately 1,400 kilometers
Duration: Between 16 to 17 hours, depending on traffic conditions.
Pro tips:
Research and map out your journey from Santiago to Buenos Aires, considering alternative routes and potential points of interest.
Familiarize yourself with the terms and conditions of your rental agreement, including insurance coverage, mileage limits, and any additional fees.
Ensure you have emergency supplies, water, snacks, and a first aid kit packed. Also, consider bringing a portable phone charger, a map, or a GPS device (in case of limited connectivity).
Respect the speed limit, traffic signs, and laws when driving in Argentina and Chile. Be aware of any tolls along the route and have local currency ready for payment.
Take caution when driving through mountainous terrain and rural areas, where the road conditions are not at their best.
A quick overview of traveling from Santiago to Buenos Aires
Mode of transport
Time
Why choose this
Flight
2 to 4 hours
Convenient
Comfortable
Fastest mode of transport.
Bus
22 to 24 hours
Budget-friendly
Scenic beauty along the way
Car
16 to 17 hours
Freedom to explore at your own pace.
Flexibility
Best way to admire South America.
There are multiple ways to get from Santiago to Buenos Aires to suit different tastes and budget ranges. For speed and convenience, opt for direct flight between the two capital cities. Taking a bus is the most affordable way to travel, but the journey time can be very long. If you love road trips and flexible traveling, renting a car is the way to go. Travel at your own sweet pace and uncover the hidden gems en route to Buenos Aires from Santiago.
For travelers enchanted by the vibrant energy of Buenos Aires, embarking on one of our packaged Buenos Aires tours offers an immersive trip to Argentina's cultural heart. Our all-inclusive tours from Santiago to Buenos Aires ensure a seamless experience, covering transportation, guided excursions to iconic landmarks like the colorful La Boca neighborhood, the historic Plaza de Mayo, and the grandeur of Recoleta Cemetery.
If you are looking for a more personalized experience, you can also reach out to our local travel experts in Argentina to create a customized trip to Argentina.
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Expect challenging hikes that reward you with sweeping vistas of glaciers, turquoise lagoons, and towering peaks. Along the way, you’ll spot guanacos grazing the steppes, Andean condors soaring overhead, and marvel at the dramatic Perito Moreno Glacier. Each day brings new discoveries, whether it’s the serenity of remote wilderness or the exhilaration of panoramic mountain views.
What sets this trekking tour apart is its immersive approach, delving deep into Patagonia’s untamed heart with expert guidance and seamless logistics—accommodation, transport, and meals are all provided. Designed for experienced travelers who relish physical challenge and natural splendor, this tour package is your ticket to the ultimate Patagonian adventure.
If you’re searching for a transformative adventure, The Great South American Journey: Quito to Rio Adventure should top your list. Designed for young adults ready for a challenge, this 65-day trip weaves through seven countries, from the Andean heights of Quito to the sun-drenched beaches of Rio de Janeiro. Trek the legendary Inca Trail, cross Bolivia’s otherworldly salt flats, soak up the rhythms of Buenos Aires, and lose yourself in Brazil’s vibrant culture. This journey is not just about sightseeing—it’s about embracing adventure, from jungle treks to cultural immersion. The unique selling point? Three nights in the Amazon and unparalleled diversity across landscapes and activities, ensuring that every day is a new chapter. With accommodation, transport, and meals included, you’ll form lifelong friendships and collect stories to last a lifetime.
Patagonia’s majestic landscapes call to the adventurous spirit, and the Journeys: Discover Patagonia tour delivers a fourteen-day odyssey through Argentina and Chile’s wild south. Starting and ending in Buenos Aires, this wildlife trip is tailored for experienced travelers and seniors who desire both comfort and active exploration. Traverse from Bariloche to the iconic Torres del Paine National Park, marvel at the mighty Perito Moreno Glacier, and spot penguins in the Beagle Channel. The journey culminates with a tango lesson in Buenos Aires, blending natural and cultural highlights. The USP of this tour package is its diverse modes of travel—by foot, boat, and private vehicle—offering a comprehensive and immersive Patagonian experience with all arrangements smoothly handled.
Uncover the pulse of South America on the Brazil, Iguazu & Argentina Delights tour—a 13-day journey weaving together legendary cities and natural marvels. Begin with Rio de Janeiro’s iconic sights before traveling along Brazil’s lush coastline to Paraty, then on to the vibrant streets of São Paulo. The itinerary’s centerpiece is the breathtaking Iguazu Falls straddling the border of Brazil and Argentina, followed by a cultural deep dive in Buenos Aires. This group tour is designed for experienced travelers and seniors seeking engaging sightseeing at a moderate pace. With included accommodation and seamless transport, the tour’s unique highlight is its combination of city vibrancy and the natural awe of Iguazu, offering a comprehensive South American experience.
Patagonia and Iguazu—two names that stir the imagination of any intrepid explorer. The "Adventures in Patagonia + Iguazu Extension" tour package is a 17-day moderate activity journey for experienced travelers, weaving together the wild beauty of South America’s southern tip with the awe-inspiring power of Iguazu Falls.
Begin in Buenos Aires, the birthplace of tango, before heading deep into Patagonia. Trek amidst the dramatic peaks of Torres del Paine, marvel at the glacial landscapes of Tierra del Fuego, and don crampons for an unforgettable hike on the Perito Moreno Glacier. The adventure doesn’t stop there—journey north to Puerto Iguazu, where thundering waterfalls and tropical rainforests provide a striking contrast to the Patagonian wilds.
All logistics, accommodations, and meals are expertly handled, allowing you to immerse yourself in the journey. The unique selling point? This trip blends two of South America’s bucket-list regions into one seamless experience, offering both iconic landscapes and vibrant local culture for a truly unforgettable adventure.
Kick off your South American adventure in Buenos Aires and wrap up with the vibrant rhythms of Rio de Janeiro on the "Buenos Aires to Rio de Janeiro: Falls & Footy" tour. Crafted for young adults eager to soak up culture and nature, this 17-day trip swings through highlights like Paraty, Iguassu Falls, and a working Uruguayan ranch. Enjoy day hikes, sample local cuisine, and experience the buzz of Copacabana’s nightlife—with centrally-located hostel stays ensuring you’re never far from the action.
This trip’s key selling point is its seamless blend of city excitement and natural wonders, featuring a quick flight to São Paulo to maximize your time on Brazil’s sun-drenched coast. For travelers who crave a lively mix of sightseeing, outdoor activities, and social exploration, this tour package truly delivers.
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Each day brings a new challenge, from trekking mountain trails to exploring lively city streets. The unique selling point of this tour package is its diverse adventure activities—combining outdoor thrills with cultural immersion—for young adults seeking an unforgettable South American getaway.
Craving the ultimate South American adventure? The Bolivia to Brazil: Highlands & Coastlines tour is a month-long odyssey connecting the best of Bolivia, Argentina, and Brazil. Tailored for young adults with a taste for both wilderness and city life, this easy-paced journey starts in La Paz and winds through surreal landscapes—think the Uyuni Salt Flats and Atacama Desert—before culminating in the vibrant rhythm of Rio de Janeiro.
Along the way, you’ll explore the cobblestone streets of Buenos Aires, sip wine with new friends, and dance the night away. The itinerary is packed with natural marvels and urban sophistication: from high-altitude vistas to coastal escapes, you’ll experience ancient cultures, striking scenery, and South America’s legendary nightlife.
The unique selling point of this trip is its remarkable diversity—pairing jaw-dropping wilderness with cosmopolitan flair, all in the company of a dynamic group of young travelers. Why choose between nature and city lights when you can have both on one unforgettable journey?
If Patagonia is calling your name, why not answer with a hike? This Patagonia Hiking trip is a nine-day adventure crafted for young adults and experienced travelers with a passion for challenging treks and epic vistas. Starting and ending in Buenos Aires, you’ll explore the wild heart of Argentina—El Chaltén’s rugged trails, the dramatic silhouette of Fitz Roy, and the icy majesty of the Perito Moreno Glacier.
Expect days filled with invigorating hikes through untamed landscapes, evenings swapping stories with fellow adventurers, and moments of awe beneath Patagonia’s vast skies. In between, discover the cosmopolitan flair of Buenos Aires, adding urban excitement to your journey.
The tour’s unique selling point is its focus on active exploration—trekking through some of South America’s most legendary wilderness, offering both physical challenge and the thrill of triumphant achievement.
Travelers who seek the perfect blend of cultural discovery and natural wonder will find it on the Andes, Iguassu & Beyond tour. Over 18 days, journey from Santiago to Rio de Janeiro, with stops in Bariloche, Buenos Aires, and the thundering Iguassu Falls. This easy-paced city sightseeing trip is designed for experienced travelers eager to explore Chile and Argentina’s highlights, from adventure sports in Pucón to the vibrant energy of Rio. The real draw of this tour package is its diverse mix of urban sophistication and breathtaking landscapes, all arranged with accommodations, meals, and transport included. Dive into South America’s best and return home with a lifetime’s worth of stories.
Craving a trekking adventure off the well-worn path? The "Hike Patagonia In Depth" tour is your ticket to 14 days of breathtaking exploration through Argentina’s most remote and spectacular landscapes. Starting and ending in Buenos Aires, this guided trip weaves through Serrano Camp, El Chaltén, Camp Los Cuernos, and beyond, diving deep into the wild heart of Patagonia.
Expect challenging, rewarding hikes amid jaw-dropping scenery—think snow-capped peaks, endless blue skies, and the legendary Torres del Paine National Park. Wander Glacier National Park’s dramatic terrain, experience the rugged charm of El Chaltén, and tackle the celebrated W Trek, where every bend reveals another ‘wow’ moment.
Perfect for young adults and experienced trekkers drawn to the thrill of the unknown, this tour offers more than just the famous highlights; it promises true immersion in Patagonia’s pristine wilderness. The unique selling point? An expertly guided, small-group adventure that delivers both iconic treks and the serene solitude of lesser-traveled trails—guaranteeing the walk of your life through South America’s last great frontier.
Argentina's vast diversity is yours to explore on the "Discovering the Best of Argentina" tour. Over 15 memorable days, young adults will journey from the icy glaciers of Patagonia to the thunderous Iguazu Falls, stroll the Parisian boulevards of Buenos Aires, witness the end of the world in Ushuaia, and sip wine in Mendoza’s sunlit vineyards. This trip expertly combines scenic wonders with immersive cultural experiences—think tango performances and outdoor adventures. The stand-out feature? A thoughtfully curated itinerary that showcases Argentina’s most spectacular contrasts, all in one unforgettable tour package.
Mishyali Fernando is a content writer from Sri Lanka with a deep passion for exploring new places and sharing her adventures through words. Growing up in such a beautiful country, she has been fortunate to travel extensively, from the cultural charm of Kandy to the misty hills of Nuwara Eliya and Ella, the vibrant streets of Jaffna, and the stunning beaches of Galle and Mirissa—her personal favorite.
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