10 Best South America Multiday Tours in September 2026

Page 19 of 320 Trips in South America during September 2026 with 831 Reviews

Puerto Maldonado Amazon Budget Eco-Lodge 6D/5N (from Cuzco) - September 2026

No booking fees

Best price guaranteed

Embark on an exhilarating journey from the ancient city of Cusco to the heart of the Amazon rainforest. Experience the captivating wildlife, dramatic landscapes, and the vibrant culture of Peru. Canoe through Lake Sandoval, zip-line through the treetops, and explore serene jungle paths. Conclude your adventure in the mystical city of Cusco, a gateway to Peru's rich history.

AdventureWildlife

Tour Type

Small Group Tour

Accommodation

Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Puerto Maldonado, Amazon Lodge Tambopata

Duration6 days

From

USD 596

View Tour

Puerto Maldonado Amazon Eco-Lodge 6D/5N (from Cuzco) - September 2026

No booking fees

Best price guaranteed

Embark on an enchanting journey where the mysteries of the Amazon rainforest meet the timeless charm of Cusco. From exploring the lush jungles of Puerto Maldonado to discovering the rich tapestry of cultures in Cusco, this six-day expedition offers an array of unforgettable experiences. Journey through diverse ecosystems, witness extraordinary wildlife, engage in authentic cultural activities, and retreat in serene accommodations—each moment crafted for adventurous souls.

AdventureWildlife

Tour Type

Small Group Tour

Accommodation

Lodge, Bungalow, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Puerto Maldonado, Amazon Lodge Tambopata

Duration6 days

From

USD 740

View Tour

Iguazu Falls Adventure 3D/2N (Puerto to Foz) - September 2026

No booking fees

Best price guaranteed

Embark on an unforgettable adventure to the breathtaking Iguazu Falls! Experience the awe-inspiring power of these natural wonders from both the Argentine and Brazilian sides. Delight in guided jungle treks, exhilarating boat rides, and scenic viewpoints offering panoramic vistas. Perfect for nature lovers and thrill-seekers, this tour promises immersive encounters with diverse flora and fauna. Capture mesmerizing photos and create lifelong memories at one of the world's most iconic waterfall destinations. Ideal for those seeking both adventure and natural beauty.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Foz Do Iguacu, Puerto Iguazu

Duration3 days

From

USD 412

View Tour

Machu Picchu by Car Backpacker Experience 2D/1N (Return by Train) - September 2026

No booking fees

Best price guaranteed

Embark on an enthralling journey through Peru's storied landscapes with Bamba Travel. Experience the wonders of the Sacred Valley, the awe-inspiring trek to Aguas Calientes, and the majesty of Machu Picchu. From imperial ruins to breathtaking sunrises, unveil the secrets of the Incas over an unforgettable two-day exploration.

ExplorerAdventure

Tour Type

Small Group Tour

Accommodation

Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Aguas Calientes

Duration2 days

From

USD 362

View Tour

Huayhuash Express 6D/5N - September 2026

No booking fees

Best price guaranteed

Embark on a breathtaking trekking adventure through the stunning Peruvian Andes with this all-inclusive Huayhuash circuit. Traverse picturesque landscapes, encounter crystal-clear alpine lakes, and gain exclusive insights into local culture. Perfect for avid hikers seeking an unforgettable, high-altitude experience, this guided expedition offers challenging trails and awe-inspiring vistas. With experienced guides, delicious meals, and comfortable campsites, immerse yourself in nature's splendor while creating lifelong memories on this top-rated trek in Peru's renowned mountain sanctuary.

AdventureTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Tent, Camping, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Huaraz, Matacancha, Laguna Jahuacocha

Duration6 days

From

USD 1,457

View Tour

Sacred Valley Trek to Machu Picchu 2D/1N - September 2026

No booking fees

Best price guaranteed

Immerse yourself in the enchanting landscapes of the Andes as you journey from the vibrant city of Cusco to the mystical ruins of Machu Picchu. This adventure-packed itinerary will take you through breathtaking mountain passages, historical Inca sites, and picturesque valleys. Relish guided tours, challenging treks, and awe-inspiring views, wrapping up with an unforgettable visit to the world-renowned Machu Picchu.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Aguas Calientes

Duration2 days

From

USD 672

View Tour

Uyuni Salt Flats & Desert Adventure 4D/3N (Atacama to La Paz) - September 2026

No booking fees

Best price guaranteed

Embark on an unforgettable Uyuni Salt Flats and Desert Adventure, journeying from Atacama to La Paz. Explore surreal landscapes of Salar de Uyuni, vibrant lagoons, and the enigmatic Dali Desert. Encounter diverse wildlife, and marvel at the stunning contrasts of the world's largest salt flat. Perfect for thrill-seekers and nature lovers, this tour includes guided excursions, comfortable 4x4 rides, and cultural experiences with local communities. Capture breathtaking photos and create lasting memories on this extraordinary adventure.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Atacama Desert, La Paz

La Paz, Atacama Desert, La Paz, Uyuni Salt Flat, Uyuni, San Pedro De Atacama

Duration4 days

From

USD 401

View Tour

Puerto Maldonado Amazon Eco-Lodge 5D/4N (from Cuzco) - September 2026

No booking fees

Best price guaranteed

Embark on an unforgettable Amazon Rainforest adventure in Puerto Maldonado, originating from Cuzco. Dive into immersive jungle excursions, night safaris, and breathtaking canopy walks at an eco-lodge nestled in the heart of pristine nature. Encounter diverse wildlife, vibrant bird species, and lush landscapes on guided tours. Experience local culture with community visits and savor exquisite regional cuisine. Ideal for nature enthusiasts and adventure seekers, this expedition promises profound connections with the Amazon's untamed beauty. Book now for an exclusive eco-friendly journey!

Adventure

Tour Type

Small Group Tour

Accommodation

Lodge, Eco Lodge, Bungalow

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Amazon Lodge Tambopata

Duration5 days

From

USD 559

View Tour

Machu Picchu by Train Adventure - September 2026

No booking fees

Best price guaranteed

Immerse yourself in the captivating world of the Incas with this unforgettable journey to Machu Picchu. Begin your adventure in Cusco, travel through the scenic Sacred Valley, and arrive at the awe-inspiring Inca Citadel. With expert local guides, explore the ancient marvel, indulge in a gourmet lunch, and return with memories etched in time.

Trekking and HikingTrain tours

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco

Duration19 hours

From

USD 532

View Tour

ATV Quad Bike Adventure to Maras & Moray - September 2026

No booking fees

Best price guaranteed

Experience a thrilling ATV adventure through Peru’s stunning Sacred Valley, exploring the ancient Moray archaeological complex and the breathtaking Maras salt mines. This action-packed tour combines adrenaline, cultural immersion, and scenic beauty, making it perfect for adventure seekers and history enthusiasts alike. Ride powerful quad bikes across rugged terrains, marvel at Incan agricultural terraces, and capture panoramic views of the Andean landscape. Join this unforgettable journey and uncover the hidden treasures of Maras and Moray on an exhilarating off-road escapade.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco

Duration6 hours

From

USD 54

View Tour

Machu Picchu by Train 2D/1N (Sleep in Aguas Calientes) - September 2026

No booking fees

Best price guaranteed

Discover the breathtaking wonder of Machu Picchu with an unforgettable train journey that culminates in exploration. Experience captivating landscapes aboard a scenic train ride, delve into ancient Inca history with guided tours, and unwind in the charming town of Aguas Calientes. This adventure offers an ideal blend of culture, history, and natural beauty. Perfect for those seeking a short, yet immersive experience of one of the world's most iconic archaeological sites.

Getaways and short breaks

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Machu Picchu, Aguas Calientes

Duration2 days

From

USD 483

View Tour

Machu Picchu Jungle Trek 4D/3N (Biking Only) - September 2026

No booking fees

Best price guaranteed

Discover an exhilarating adventure in the heart of Peru with an unforgettable biking expedition to Machu Picchu. Pedal through lush jungle landscapes, traverse scenic mountain trails, and marvel at breathtaking ancient ruins on this thrilling journey. Perfect for adrenaline seekers and nature lovers, this tour offers a unique blend of adventure and cultural exploration. Unveil the hidden treasures of the Andes while enjoying guided bike rides and immersive local experiences—an ultimate getaway for your bucket list.

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Machu Picchu, Santa Maria

Cusco, Machu Picchu, Santa Maria, Santa Teresa, Aguas Calientes

Duration4 days

From

USD 636

View Tour

Iquitos Amazon Jungle Adventure 5D/4N - September 2026

No booking fees

Best price guaranteed

Discover an unforgettable Amazon jungle adventure in Iquitos, offering immersive wildlife encounters, guided rainforest hikes, and serene boat tours. This tour includes vibrant visits to native communities, exploration of exotic flora and fauna, and fascinating night safaris. Guests can enjoy comfortable accommodations while experiencing the pristine beauty of the Amazon River and its rich biodiversity. Ideal for nature enthusiasts and adventurous travelers looking for a unique, eco-friendly escape in the heart of the Peruvian Amazon.

ExplorerAdventure

Tour Type

Small Group Tour

Accommodation

Lodge, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Amazon Peru, Iquitos, Amazon Lod

Amazon Peru, Iquitos, Amazon Lodge Tambopata, Lima

Duration5 days

From

USD 879

View Tour

Iquitos Amazon Jungle Adventure 3D/2N - September 2026

No booking fees

Best price guaranteed

Explore the heart of the Peruvian Amazon with a thrilling jungle adventure in Iquitos. Experience exotic wildlife, guided hikes, and canoe trips through lush rainforests. Marvel at diverse flora and fauna, spot pink river dolphins, and visit indigenous communities. This immersive Amazon journey offers unparalleled opportunities for nature photography and birdwatching. Adventure-seekers and nature enthusiasts will love the unique blend of cultural encounters and breathtaking natural scenery. Book now for a memorable eco-tourism experience in one of the world's most biodiverse regions!

ExplorerAdventure

Tour Type

Small Group Tour

Accommodation

Lodge, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Amazon Peru, Iquitos, Lima

Duration3 days

From

USD 600

View Tour

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All South America Tours in September 2026

Page 19 of 320 Trips in South America during September 2026 with 831 Reviews

Page 19 of 320 Trips in South America during September 2026 with 831 Reviews