10 Best South America Multiday Tours in September 2026

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Inca Trail & the Amazon Rainforest - September 2026

4.9

(118 reviews )

No booking fees

Best price guaranteed

I was primarily interested in the Inka Trail and Machu Pichu but the rain forest and Lake Titicaca were brilliant. Three holidays in one.

Trekking and HikingAdventure

Tour Type

Small Group Tour

Accommodation

Hotel, Camping, Lodge, Home-stay, Tent

Age Range

16-99 yrs

Operated in

english

Destinations

Lima, Machu Picchu, Cusco, Puno

Lima, Machu Picchu, Cusco, Puno, Amantani Homestay, Tambopata, Inca Trail

Duration15 days

From

USD 7,350

USD 7,130

Saving

USD 221

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Super Sales

Costa Rica's Coastal Secrets - September 2026

4.8

(81 reviews )

No booking fees

Best price guaranteed

This is a new option for prospective visitors to Costa Rica and one I would unreservedly recommend. The anticipated daily downpours didn't materialise [ though, of course there was some rain ], and we spent most of the trip observing fantastic wildlife in dense jungle or warm, blue seas under blue skies. The hotels were all comfortable and well located and the mix between activity and leisure was well planned.

Marine wildlifeWildlife

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Villa, Resort

Age Range

16-99 yrs

Operated in

english

Destinations

San Jose, Tortuguero National Pa

San Jose, Tortuguero National Park, Osa Peninsula, Cahuita National Park, Caño Island, Corcovado National Park, Turrialba, Savegre Cloud Forest

Duration15 days

From

USD 6,000

USD 5,820

Saving

USD 180

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Lake Titicaca & Isla del Sol Explorer 3D/2N (La Paz to Cuzco) - September 2026

No booking fees

Best price guaranteed

Embark on an unforgettable adventure exploring Lake Titicaca and the enchanting Isla del Sol. This journey offers breathtaking views, rich cultural experiences, and hands-on adventures. Highlights include boat rides on the world's highest navigable lake, ancient Inca ruins, and immersive interactions with local communities. Wander through Bolivia's cultural hubs and Peru's scenic landscapes, perfect for travelers seeking both relaxation and thrilling exploration. Enhance your South American odyssey with this unique and scenic travel experience. Secure your spot now and delve into the mystical beauty of the Andes.

AdventureExplorer

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, La Paz, La Paz, Isla Del Sol

Duration3 days

From

USD 155

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Salkantay Trek to Machu Picchu - September 2026

4.9

(12 reviews )

Trip customizable

Best price guaranteed

Well prepared Salkantay trek 5d/5n zone with Saul G as a guide and Gregorio as a chef and Cesar and Walter as porters. Good food all the way and amazing places to sleep such as the hobbit houses and the star gazing houses the very first night. Bonus was the lomo saltado cooking class and the visit of a coffee farm.

Trekking and HikingCamping

Tour Type

Small Group Tour

Accommodation

Camping, Eco Lodge, Hotel, Lodge, Tent

Age Range

10-65 yrs

Operated in

english, spanish

Destinations

Salkantay, Machu Picchu, Aguas C

Salkantay, Machu Picchu, Aguas Calientes, Humantay, Cusco, Soraypampa, Ccollpapampa, Llactapata

Duration8 days

From

USD 870

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Salkantay Trek & Machu Picchu - September 2026

27% OFF TODAY

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Salkantay Trek & Machu Picchu - September 2026

(8 reviews )

No booking fees

Best price guaranteed

Absolutely amazing is all I can say. The hike was definitely one of the hardest things I’ve ever done, but it was so worth it. Our guides made sure that we had the best overall experience and I would recommend G adventures to everyone! The scenic views throughout the hike were absolutely breathtaking. The food was really good and we had no issues with our accommodations or travel. Thanks again to all the wonderful staff at G adventures that were with us throughout our Journey!

WildlifeTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Camping, Villa

Age Range

12-100 yrs

Operated in

english

Destinations

Cusco, Machu Picchu, Lima, Wayra

Cusco, Machu Picchu, Lima, Wayraqmachay, Sahuayaco, Aguas Calientes

27% OFF TODAY

Duration5 days

From

USD 699

USD 508

Saving

USD 191

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Super Sales

Journeys: Treasures of Peru & Bolivia - September 2026

4.9

(11 reviews )

No booking fees

Best price guaranteed

I had a great time with Gadventures trip to Peru and Boliva. I highly recommend Gadventures, National Geographic small group trips. I believe these trips offer special insight into the local cultures.

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

12-100 yrs

Operated in

english

Destinations

Lima, La Paz, Sucre, Potosi, Uyu

Lima, La Paz, Sucre, Potosi, Uyuni, Urubamba, Aguas Calientes, Cusco, Copacabana

Duration16 days

From

USD 5,199

USD 5,043

Saving

USD 156

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Amazing Central America - September 2026

13% OFF TODAY

Super Sales

Amazing Central America - September 2026

No booking fees

Best price guaranteed

Get ready for a 28-day adventure through Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica and Panama. From oceans teeming with marine life to tropical forests alive with jungle melodies, this pocket of Central America is truly a natural paradise. You’ll explore the intricately carved structures at Copan, the cloud forests of Monteverde and spend three nights in the island paradise of Bocas del Toro. Sample varied cuisines along the way during cooking lessons with locals, giving you a real insight into the heart and soul of Central America.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Hut

Age Range

15-99 yrs

Operated in

english

Destinations

Panama City, San Jose, Antigua

Panama City, San Jose, Antigua, Monteverde Cloud Forest Biological Preserve, Puerto Viejo de Talamanca, Cahuita National Park, Ometepe Island, La Fortuna, Copan, Isla Colon, Bocas Del Toro, Boquete, Santa Catalina, Suchitoto, El Cuco, Leon, Granada

13% OFF TODAY

Duration28 days

From

USD 4,030

USD 3,518

Saving

USD 512

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Basic Central America: Guatemala To Costa Rica - September 2026

27% OFF TODAY

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Basic Central America: Guatemala to Costa Rica - September 2026

(7 reviews )

No booking fees

Best price guaranteed

Overall, a wonderful trip! The pace is fast and the amount of things provided to do was very good. I would have liked to have spent a little more time in Guatemala and Honduras to get a feel for those countries (I can't really say that I have seen them on this trip) yet overall, it was a wonderful time with amazing people and beautiful locations.

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Home-stay, Hostel, Hotel, Resort

Age Range

12-100 yrs

Operated in

english

Destinations

San Jose, Antigua, Ometepe, Mont

San Jose, Antigua, Ometepe, Monteverde, La Fortuna, Copan, Suchitoto, La Libertad, Leon, Granada

27% OFF TODAY

Duration17 days

From

USD 1,649

USD 1,199

Saving

USD 450

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Volcano Trail: Waves & Local Ways - September 2026

18% OFF TODAY

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Volcano Trail: Waves & Local Ways - September 2026

(8 reviews )

No booking fees

Best price guaranteed

Super charged adventure.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel, Home-stay, Guest House, Resort

Age Range

18-39 yrs

Operated in

english

Destinations

San Jose, Antigua, Isla Ometepe

San Jose, Antigua, Isla Ometepe, Monteverde Cloud Forest Biological Preserve, La Fortuna, Copan, Roatan, Granada

18% OFF TODAY

Duration17 days

From

USD 1,649

USD 1,359

Saving

USD 290

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13% OFF TODAY

Super Sales

Costa Rica Experience - September 2026

No booking fees

Best price guaranteed

Discover a region of natural diversity, cultural riches and laidback vibes on an eight-day jungle jaunt through Costa Rica. Thanks to a longstanding tradition of preserving its natural assets, much of the country’s primary rainforest still stands. Opportunities for nature-based activities are endless here and the beaches on both coasts are well worth your free time. Spot monkeys and sloths in the cloud forests of Monteverde, hike to hidden waterfalls and kick back on the beach at Manuel Antonio. Explore the depths of this vibrant country with plenty of time to make this trip your own.

Active and outdoor

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

San Jose, Manuel Antonio Nationa

San Jose, Manuel Antonio National Park, La Fortuna, Monteverde Cloud Forest Biological Preserve, Arenal Volcano, Santa Rosa De Pocosol, Arenal, Quepos

13% OFF TODAY

Duration8 days

From

USD 1,360

USD 1,187

Saving

USD 173

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Atacama & Uyuni Salt Flats Adventure 7D/6N - September 2026

No booking fees

Best price guaranteed

Embark on an unforgettable adventure through the breathtaking landscapes of the Atacama Desert and Uyuni Salt Flats. Discover awe-inspiring sights like Moon Valley, the striking Red Lagoon, and the world-renowned Uyuni Salt Flats. Experience unique activities such as stargazing in one of the clearest night skies on Earth and exploring surreal rock formations. This tour promises an immersive journey filled with natural wonders, perfect for travelers seeking extraordinary experiences in South America's most dramatic desert scenery.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Uyuni, Calama, San Pedro De Atac

Uyuni, Calama, San Pedro De Atacama, Villamar Mallcu

Duration7 days

From

USD 1,179

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Super Sales

Epic Mexico to Costa Rica - September 2026

No booking fees

Best price guaranteed

From cloud forests and volcanic peaks to sun-drenched island beaches and lost temples, Central America is bursting with natural wonders and converging cultures. On this epic 32-day adventure, you’ll kick off in Mexico’s Playa del Carmen and snake through Belize, Guatemala, El Salvador, Nicaragua and Costa Rica. Relax by colourful architecture in San Miguel, trek to the jungle ruins of Tikal, brush up on your Espanol over an icy cerveza and stay in villages dwarfed by volcanoes. Whether you’re haggling in the markets of Chichicastenango, chilling in a Caribbean town on the Rio Dulce or wandering cobblestone streets in Antigua, you'll be discovering new places and forging lifelong friendships along the way. From ancient Maya ruins to modern nightlife, you’ll explore the sights and sounds of Latin life and dive into the wilds of seldom-seen hotspots.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel, Lodge, Camping

Age Range

18-35 yrs

Operated in

english

Destinations

San Jose, Playa Del Carmen, Rio

San Jose, Playa Del Carmen, Rio Dulce, Antigua, San Jorge La Laguna, Panajachel, Suchitoto, El Tunco, Tulum, El Cuco, Leon, Granada, Ometepe Island, Monteverde Cloud Forest Biological Preserve, La Fortuna, Caye Caulker, San Ignacio, Tikal

Duration32 days

From

USD 2,915

USD 2,828

Saving

USD 87

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Super Sales

Central American Adventure - September 2026

(1 review )

No booking fees

Best price guaranteed

Explore colourful worlds – both on land and underwater – on a vibrant adventure from the sunny beaches of Mexico through jungle and Caribbean coastline to the volcanic mountains of Costa Rica. This 34-day adventure hits Mexico, Belize, Guatemala, Honduras, El Salvador, Nicaragua and Costa Rica, snaking through all the best spots and introducing you to local haunts as well as traveller hotspots. Discover a diverse marine playground in Caye Caulker, walk through the steamy cloud forests in Monteverde and visit the famous Tikal pyramids, arguably the most stunning of Guatemala’s ruins. Learn ancient Maya secrets and pass through jaw-dropping scenery on this Central American adventure.

Wildlife

Tour Type

Small Group Tour

Accommodation

Hotel, Hut, Lodge

Age Range

15-99 yrs

Operated in

english

Destinations

San Jose, Playa Del Carmen, Rio

San Jose, Playa Del Carmen, Rio Dulce, Antigua, San Jorge La Laguna, Panajachel, Copan, Suchitoto, El Cuco, Leon, Granada, Ometepe Island, Monteverde Cloud Forest Biological Preserve, Tulum, La Fortuna, Caye Caulker, San Ignacio, Tikal

Duration34 days

From

USD 4,480

USD 4,346

Saving

USD 134

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Super Sales

Trekking the Inca Trail: 4D/3N - September 2026

4.9

(28 reviews )

No booking fees

Best price guaranteed

The guides, chef, and porters are all amazing. The food on the Inca trail is exceptional. How they do it, I don't know. This is a hard hike but you are well taken care of.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Camping

Age Range

12-100 yrs

Operated in

english

Destinations

Chiclayo, Inca Trail, Cusco

Duration4 days

From

USD 779

USD 756

Saving

USD 23

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All South America Tours in September 2026

Page 5 of 915 Trips in South America during September 2026 with 2,962 Reviews

Inca Trail & the Amazon Rainforest - September 2026

Costa Rica's Coastal Secrets - September 2026

Lake Titicaca & Isla del Sol Explorer 3D/2N (La Paz to Cuzco) - September 2026

Salkantay Trek to Machu Picchu - September 2026

Salkantay Trek & Machu Picchu - September 2026

Journeys: Treasures of Peru & Bolivia - September 2026

Amazing Central America - September 2026

Basic Central America: Guatemala to Costa Rica - September 2026

Volcano Trail: Waves & Local Ways - September 2026

Costa Rica Experience - September 2026

Atacama & Uyuni Salt Flats Adventure 7D/6N - September 2026

Epic Mexico to Costa Rica - September 2026

Central American Adventure - September 2026

Trekking the Inca Trail: 4D/3N - September 2026

Page 5 of 915 Trips in South America during September 2026 with 2,962 Reviews

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All South America Tours in September 2026

Page 5 of 915 Trips in South America during September 2026 with 2,962 Reviews

Page 5 of 915 Trips in South America during September 2026 with 2,962 Reviews