10 Best South America Multiday Tours in September 2026

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Cafe Colombia - September 2026

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Head into the serene highlands of Colombia's famed coffee region and discover the sweeter, softer side of this misunderstood country. Learn how to roast the perfect blend during a tour of a working coffee plantation, be entranced by the laidback pace of Salento and maybe explore the nightlife of Medellin. Then, trade the country's lush interior for its coastal spoils and wind the adventure up in oh-so-romantic Cartagena – UNESCO World Heritage site with much to explore.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Bogota, Cartagena, Salento, Haci

Bogota, Cartagena, Salento, Hacienda Coffee Farm, Medellin

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Duration9 days

From

USD 2,820

USD 2,052

Saving

USD 768

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Argentina & Brazil Adventure - September 2026

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Argentina & Brazil Adventure - September 2026

(1 review )

No booking fees

Best price guaranteed

Get an invigorating taste of South America’s south on a trip that takes you from Buenos Aires to Rio de Janeiro. Let the sounds of samba wash over you and get swept up in the infectious energy of the locals. Stroll white-sand beaches in Rio, rummage through antique fairs in Buenos Aires and sample delicious culinary specialties wherever you go. In between these two vibrant cities, become immersed in spectacular wilderness - from the sprawling wetlands of Ibera to the astonishing Iguazu Falls, there’s a trove of natural beauty waiting for you.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, It

Buenos Aires, Rio de Janeiro, Ituzaingo, Foz Do Iguazu, Iguazu Falls

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Duration10 days

From

USD 4,470

USD 3,252

Saving

USD 1,218

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Essential Peru - September 2026

4.8

(175 reviews )

No booking fees

Best price guaranteed

Fantastic holiday , A real adventure. We saw sights I had only dreamed about. Every day there was something new to wonder at, from the desert at Nasca , to Machu Picchu to Colca Canyon. Fantastic.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Home-stay, Villa

Age Range

16-99 yrs

Operated in

english

Destinations

Lima, Amantani, Puno, Arequipa

Lima, Amantani, Puno, Arequipa, Ica, Nazca, Abancay, Cusco, Aguas Calientes, Machu Picchu

Duration15 days

From

USD 3,520

USD 3,414

Saving

USD 106

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22% OFF TODAY

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Classic Peru - September 2026

(1 review )

No booking fees

Best price guaranteed

Travel to Peru on an adventure from mountains and jungle to seasides to great plains. Across nine days, you’ll see the incredible natural and historical highlights of this adventure capital. Retrace the steps of the Incas to Machu Picchu (one of the famed Seven Wonders of the World), learn the histories of colonial cities, explore vibrant markets and meet the locals – all with a local right by your side. Return home with incredible memories of the panoramas and people of Peru.

Sightseeing Tours

Tour Type

Small Group Tour

Accommodation

Hotel, Home-stay

Age Range

15-99 yrs

Operated in

english

Destinations

Lima, Cusco, Aguas Calientes, Puno

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Duration9 days

From

USD 2,775

USD 2,153

Saving

USD 622

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Southern Divide - September 2026

(8 reviews )

No booking fees

Best price guaranteed

Lima and Santiago bookended this trip. The small cities and towns we visited were more to my taste. La Paz was special in part because of a very good city tour largely on the cable card.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Resort, Guest House

Age Range

12-100 yrs

Operated in

english

Destinations

Santiago, Lima, La Paz, Sucre, P

Santiago, Lima, La Paz, Sucre, Potosi, Uyuni, Salar De Uyuni, San Pedro De Atacama, Cusco, Ollantaytambo, Aguas Calientes, Puno

Duration21 days

From

USD 4,499

USD 4,364

Saving

USD 135

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Lima to Rio: Coast to Coast - September 2026

(8 reviews )

No booking fees

Best price guaranteed

Incredible trip and glad I did this through G. Very fast paced which took time getting used to so be aware if prefer slow and steady.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Lodge, Hotel, Hostel, Bungalow, Home-stay, Villa, Camping

Age Range

18-39 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Cusco, Oll

Rio de Janeiro, Lima, Cusco, Ollantaytambo, Llactapata, Dead Woman's Pass, Wiñay Wayna, Puno, Lake Titicaca, Paracas, La Paz, Sucre, Potosi, Uyuni, Salar De Uyuni, Nazca, San Pedro De Atacama, Salta, Buenos Aires, Colonia, Montevideo, Arequipa, Estancia, Iguassu National Park, Iguazu Falls, Paraty, Ilha Grande, Colca Canyon

Duration51 days

From

USD 8,299

USD 8,050

Saving

USD 249

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Inland & Amazon - September 2026

4.9

(10 reviews )

No booking fees

Best price guaranteed

Loved my first GAdventure trip and definitely more to come. Our guide Carlos with very informative, time management was good and he was always readily available to assist with any request. Beautiful destinations, great excursions and free time to explore on my own Had an amazing group of people for my 2 week journey and felt like family.

Rainforest and jungle visits

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Hut

Age Range

12-100 yrs

Operated in

english

Destinations

Quito, Cuenca, Banos, Tena, Papa

Quito, Cuenca, Banos, Tena, Papallacta, Otavalo, Cotopaxi National Park

Duration14 days

From

USD 2,249

USD 2,182

Saving

USD 67

Instant book available

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Peru: Ancient Cities & The Andes - September 2026

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Peru: Ancient Cities & the Andes - September 2026

(9 reviews )

No booking fees

Best price guaranteed

I have never had a better time in my life.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Home-stay, Camping, Villa

Age Range

18-39 yrs

Operated in

english

Destinations

Cusco, Lima, Inca Trail, Nazca

Cusco, Lima, Inca Trail, Nazca, Arequipa, Colca Canyon, Ccaccaccollo Community, Ollantaytambo

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Duration14 days

From

USD 2,399

USD 1,745

Saving

USD 654

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Absolute Peru - September 2026

(9 reviews )

No booking fees

Best price guaranteed

The 21 day adventure exceeded my expectations. It provided a wonderful introduction to the history and diversity of Peru’s culture. The hike to Machu Picchu was, in places, challenging but imminently doable. The tour leaders were knowledgeable, friendly, engaging and interesting people. My desire to participate in another G Adventures tour is driven in large part by the quality of their tour leaders.

WildlifeTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Home-stay, Guest House, Camping

Age Range

12-100 yrs

Operated in

english

Destinations

Lima, Cusco, Ollantaytambo, Agua

Lima, Cusco, Ollantaytambo, Aguas Calientes, Tambopata Reserve, Paracas, Nazca, Arequipa, Colca Canyon, Puno, Lake Titicaca

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Duration21 days

From

USD 4,779

USD 3,476

Saving

USD 1,303

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Best of South America - September 2026

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Take a deep dive into Peru, Bolivia, Argentina, Uruguay and Brazil on an epic 51-day trip. With local leaders guiding you to the best neighbourhoods as well as plenty of time to explore independently, you’ll wonder what took you so long to appreciate this corner of the globe. Trek or train to the lost Inca citadel of Machu Picchu, spend a few days on an estancia in Uruguay, take a 4WD adventure through the Andean desert to the Uyuni salt flats and wind up in all the best cities – Buenos Aires, La Paz and Lima, to name a few. Finish up with beach and party vibes in Brazil – a perfect spot to chill out after your adventure to South America’s hotspots.

City sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel, Camping, Home-stay

Age Range

15-99 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Cusco, Inc

Rio de Janeiro, Lima, Cusco, Inca Trail, Machu Picchu, Lake Titicaca, Puno, La Paz, Sucre, Potosi, Uyuni, Salar De Uyuni, Ballestas Islands and Paracas National Reserve, Tilcara, Buenos Aires, Colonia Del Sacramento, Estancia, Iguazu Falls, Iguazu Falls, Nazca, Paraty, Ilha Grande, Arequipa, Colca Canyon

Duration51 days

From

USD 9,115

USD 8,842

Saving

USD 273

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Classic Inca Trail 4 Days to Machu Picchu - September 2026

(24 reviews )

Trip customizable

Best price guaranteed

I can't recommend this tour enough. Well organized, amazing experience. Hiking was beautiful and the porters and staff were so hard working, they carried everything, set-up camp for us every day/night and allowed guests to immerse in the magic of the Incan culture and natural beauty unencumbered. Also - the food, which was cooked fresh every day for breakfast, lunch and dinner was delicious, healthy and made with care.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Camping, Hotel, Tent

Age Range

8-70 yrs

Operated in

english, spanish

Destinations

Inca Trail, Cusco, Machu Picchu

Inca Trail, Cusco, Machu Picchu, Llactapata, Runkuraqay, Wiñay Wayna

Duration4 days

From

USD 760

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Central America Explorer - September 2026

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Central America Explorer - September 2026

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Dive into Central America on this 47-day adventure, bookended by two chaotic capitals and filled with fun, adventure and culture. Journey through Mexico, Belize, Guatemala, Honduras, El Salvador, Nicaragua and Costa Rica on an adventure through the tantalising highlights of the region. Get acquainted with Central American cultures, spectacular landscapes and fascinating histories as you explore the wealth of ancient ruins, spot the range of unusual wildlife and relax on idyllic Caribbean shores. This is one of our longest adventures through Central America – a trip that zig-zags from the top of the Yucatan peninsula to the highlands of Costa Rica.

WildlifeCustom private toue

Tour Type

Small Group Tour

Accommodation

Hotel, Hut, Lodge, Home-stay

Age Range

15-99 yrs

Operated in

english

Destinations

Mexico City, San Jose, Palenque

Mexico City, San Jose, Palenque, Merida, Playa Del Carmen, Tulum, Caye Caulker, San Ignacio, Tikal, Rio Dulce, Antigua, San Jorge La Laguna, Panajachel, Puebla, Copan, Suchitoto, El Cuco, Leon, Granada, Ometepe Island, Monteverde Cloud Forest Biological Preserve, La Fortuna, Oaxaca, San Cristobal De Las Casas

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Duration47 days

From

USD 8,395

USD 7,329

Saving

USD 1,066

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Best Of Peru, Argentina & Brazil - September 2026

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Best of Peru, Argentina & Brazil - September 2026

No booking fees

Best price guaranteed

There are many sides to South America, from the energy of the cities, the beauty of the lansdcapes and the spirit of its people. Discover it all on this trip that winds through the Inca heartlands and jungles of Peru, the enigmatic cities and natural wonders of Argentina and the dynamism of Brazil's vivacious Rio. See animals, meet locals, traverse trails and marvel at all the contrasts of this very special corner of the world.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Sacred Val

Rio de Janeiro, Lima, Sacred Valley, Aguas Calientes, Cusco, Buenos Aires, Foz Do Iguazu, Foz Do Iguacu, Ballestas Islands and Paracas National Reserve, Nazca, Arequipa, Lake Titicaca, Puno

13% OFF TODAY

Duration21 days

From

USD 9,360

USD 8,171

Saving

USD 1,189

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27% OFF TODAY

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Bolivia Discovery - September 2026

4.9

(9 reviews )

No booking fees

Best price guaranteed

I came for the salt flats but got to discover that Bolivia has so much more to offer with its culture, history, and different terrains. I appreciated being able to see both the cities and nature. It was special to witness a culture so connected to the land and Indigenous people. The CEO was exceptional: approachable, communicative, kind, informative, organized, attentive and passionate.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Bungalow

Age Range

12-100 yrs

Operated in

english

Destinations

La Paz, Sucre, Potosi, Uyuni, Salt Flats

27% OFF TODAY

Duration11 days

From

USD 1,799

USD 1,309

Saving

USD 490

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All South America Tours in September 2026

Page 2 of 250 Trips in South America during September 2026 with 1,221 Reviews

Cafe Colombia - September 2026

Argentina & Brazil Adventure - September 2026

Essential Peru - September 2026

Classic Peru - September 2026

Southern Divide - September 2026

Lima to Rio: Coast to Coast - September 2026

Inland & Amazon - September 2026

Peru: Ancient Cities & the Andes - September 2026

Absolute Peru - September 2026

Best of South America - September 2026

Classic Inca Trail 4 Days to Machu Picchu - September 2026

Central America Explorer - September 2026

Best of Peru, Argentina & Brazil - September 2026

Bolivia Discovery - September 2026

Page 2 of 250 Trips in South America during September 2026 with 1,221 Reviews

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All South America Tours in September 2026

Page 2 of 250 Trips in South America during September 2026 with 1,221 Reviews

Page 2 of 250 Trips in South America during September 2026 with 1,221 Reviews