10 Best South America Multiday Tours in October 2025

Buenos Aires & Patagonia Family Exploration - October 2025

4.7

(3 reviews )

Trip customizable

Best price guaranteed

We just returned from a 5-week trip to South America. The travel team was AMAZING. They helped us plan a very complex itinerary that included multiple cities in Chile and Peru, a side-trip to Easter Island, Machu Picchu and the sacred valley, and finally Iguazu Falls in Argentina and Peru. The advice they gave and the hotels they chose were truly exceptional. The detailed day-by-day itinerary was very helpful, and all of their in-country partners (e.g., drivers, tour guides) were terrific. Everything went perfectly. Best travel experience ever! Thank you, Analia and Antonella!!!

Natural landmarks sightseeing

Tour Type

Private Tour

Accommodation

Hotel

Age Range

1-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, El Calafate, San C

Buenos Aires, El Calafate, San Carlos de Bariloche, Perito Moreno Glacier, Nahuel Huapi National Park

Duration10 days

From

USD 4,245

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7-Day Rio de Janeiro & Buzios - October 2025

Trip customizable

Best price guaranteed

Descubra las emblematicas ciudades de Rio de Janeiro y Buzios. En Rio, visitará el famoso monumento Cristo Redentor y la Montaña Pan de Azúcar, y podrá explorar los alrededores con un paseo por la ciudad. En Buzios, disfrute un paseo en barco por la paradisíaca localidad de Arraial do Cabo El paquete Rio de Janeiro y Buzios Clásicos incluye siete noches de hotel, excursiones con traslados desde su hotel, y transfers desde y hacia el aeropuerto y entre localidades. EL mejor viaje de turismo en Brasil para quien quiere desenchufarse del stress diario

Sightseeing Tours

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-79 yrs

Operated in

english

Destinations

Rio de Janeiro, Buzios, Arraial Do Cabo

Duration7 days

From

USD 1,105

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Santa Cruz Island Diving Adventure 7D/6N - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable Galapagos diving experience, exploring the underwater wonders of Santa Cruz Island. This adventure promises encounters with vibrant marine life, from playful sea lions to majestic hammerhead sharks. Perfect for diving enthusiasts, you'll explore some of the world's most pristine dive sites. Highlights include daily guided dives, visits to iconic spots like Charles Darwin Station, and luxury accommodation nestled in this unique archipelago. Dive into the adventure of a lifetime and discover the unparalleled beauty of the Galapagos Islands.

AdventureWildlifeBicycle tours

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Quito, Amazon Ecuador, Santa Cruz

Duration7 days

From

USD 2,125

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North Argentina Highlights - 12 days - October 2025

No booking fees

Best price guaranteed

Take a journey through Argentina’s great rugged northwest, a land of infinite variety from ochre deserts to snow-capped mountains. Explore colonial towns, traditional Indian villages and pre-Inca ruins along the way with spectacular gorges to feast your eyes on.

Cultural, religious and historic sites

Tour Type

Private Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Buenos Aires, Tafí Del Valle, Sa

Buenos Aires, Tafí Del Valle, Salta, Purmamarca, Cafayate

Duration12 days

From

USD 2,445

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Lost City of Colombia - 8 days - October 2025

No booking fees

Best price guaranteed

TREKKING HOLIDAY: Embark on a 5 day trek through lush jungle and local settlements to uncover Colombia's Lost City, overnighting in rustic camps along the way. Climb the 1,200 stone steps which lead to the Ciudad Perdida, a fascinating site made up of stepped terraces carved into the side of a mountain. Top off your stay with some relaxation by the beach in Tayrona National Park.

Cultural, religious and historic sites

Tour Type

Private Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Bogota, Santa Marta, Adan's Camp

Bogota, Santa Marta, Adan's Camp, Rio Buritaca, Ciudad Perdida, Tayrona National Park

Duration8 days

From

USD 2,545

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Best of Ecuador and Galapagos Cruise - October 2025

Trip customizable

Best price guaranteed

Discover one of the most breathtaking destinations in Latin America with this small group tour of Ecuador and the Galapagos! Cruise along the turquoise waters and search for exotic species of animals in the Galapagos Islands! Begin your journey in Quito, the capital city of Ecuador surrounded by the Andes Mountains, where you will discover the Middle of the World and visit La Ronda. Explore the Otavalo Indian Market and Cuicocha Crater Lake before you travel to Papallacta, famous for its Natural Hot Springs and breathtaking landscapes. Explore the Amazonian Tropical Forest and discover the Manto de la Novia and Pailon del Diablo Waterfalls in Baños along with the gorgeous views of the Tungurahua Volcano! Head on a breathtaking cruise of the Galapagos Islands as you visit Sant Cruz, where you may see Giant Tortoises in their natural environment, sail to Floreana Island, an evergreen island with flaming pink-flamingos and incredible snorkeling opportunities, and explore Espanola, where animals reign the land! Encounter the Waved Albatross and pass by El Soplador, a giant blowhole that explodes to heights reaching 25 feet. Discover Blue Footed Boobies and Red-Billed Tropicbird among many other exotic species of animals before you travel to San Cristobal, the capital of the Galapagos, famous for their sea lions and volcanic rocks where you will end your tour of Ecuador and the Galapagos Islands.

Cruise

Tour Type

Group Tour

Accommodation

Ship Cabin, Lodge, Hotel

Age Range

8-99 yrs

Operated in

english

Destinations

Quito, Galapagos Islands, Amazon

Quito, Galapagos Islands, Amazon Ecuador, Floreana Island, Darwin Bay, Otavalo, Papallacta, Amazon Jungle Lodge, Banos, Guayaquil

Duration12 days

From

USD 3,727

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A Taste Of Costa Rica - October 2025

Trip customizable

Best price guaranteed

Get a taste of paradise as you discover truly breathtaking attractions with this tour of Costa Rica! Begin your journey in San Jose, the bustling capital, surrounded by evergreen mountains and valleys. This is the perfect place to discover cultural icons, famous landmarks, and key neighborhoods with historical significance! Travel to Tamarindo, known for its beautiful beaches which make it the picture-perfect paradise to relax in! Spend your days soaking in the bright sunshine, splashing around the gorgeous turquoise waters, and taking part in all types of aquatic activities. Tamarindo is also famous for its diverse wildlife so be prepared to have some encounters with incredible creatures. From there you will head back to San Jose where you will end your tour of Costa Rica!

Rainforest and jungle visits

Tour Type

Independent Tour

Accommodation

Hotel

Age Range

8-99 yrs

Operated in

English

Destinations

San Jose, Guanacaste, Tamarindo

San Jose, Guanacaste, Tamarindo Beach, Tamarindo

Duration5 days

From

USD 1,102

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Treasures Of Argentina - October 2025

Trip customizable

Best price guaranteed

This small-group tour of Argentina will be the perfect trip for any first-time traveler to South America! Discover three of the most extraordinary cities in the country and immerse yourself in the rich culture of the land with this fascinating journey. Begin your tour in Buenos Aires; visit Plaza de Mayo and explore La Boca, where you will discover extraordinary museums and learn about the birthplace of tango. Catch your flight to El Calafate where will head on a breathtaking tour of the Perito Moreno Glacier from various viewpoints with a trip to Los Glaciares National Park. Make your way back to Buenos Aires and travel to Iguazu. Visit Iguazú National Park and see the world-famous falls with a visit to the Devil's Throat viewpoint, along with the Upper and Lower Trails. Arrive in Foz do Iguaçu in Brazil, where you will see the beauty of the falls from a whole new perspective. Catch your flight back to Buenos Aires where your tour of Argentina will end!

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hotel

Age Range

8-99 yrs

Operated in

english

Destinations

Buenos Aires, Puerto Iguazu, El Calafate

Duration10 days

From

USD 2,519

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Picturesque Solo Costa Rica Tour - October 2025

Trip customizable

Best price guaranteed

This solo tour will take you on a magical journey through tropical rainforests, breathtaking beaches, teeming volcanoes, and sky-high cloud forests. Discover the perfect mix of exhilarating adventures and awe-inspiring scenery as you explore some of the most beautiful regions in Costa Rica. Begin your journey in San Jose, the bustling capital of Costa Rica surrounded by evergreen mountains and breathtaking valleys. Next, you will drive to Arenal, situated in a breathtaking setting unspoiled by tourists. There you may choose to climb the Arenal Volcano, one of the largest stratovolcanoes in Costa Rica. Enjoy a boat ride to Monteverde, home to the breathtaking Cloud Forest with hundreds of species of reptiles and amphibians, mammals, birds, and plants. Travel to Manuel Antonio to explore the gorgeous beaches, rich wildlife, and endless list of activities of the area before you return to San Jose to end your tour of Costa Rica! This is a Solo Tour You don't pay single supplement and get a room for yourself!

Rainforest and jungle visits

Tour Type

Small Group Tour

Accommodation

Hotel, Villa

Age Range

8-99 yrs

Operated in

english

Destinations

San Jose, Manuel Antonio Nationa

San Jose, Manuel Antonio National Park, Arenal Volcano, Arenal, Monteverde Cloud Forest Biological Preserve, Manuel Antonio

Duration8 days

From

USD 1,889

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Costa Rican Explorer - October 2025

Trip customizable

Best price guaranteed

This tour of Costa Rica will guide you through the natural wonders and breathtaking sights of this tropical gem! Begin your journey in San Jose, the famous capital, which is surrounded by evergreen mountains and valleys with plenty of cultural attractions. From there you will visit Tortuguero National Park, the nesting grounds of green sea turtles with its breathtaking beaches and fantastic opportunities to spot wild animals and birds. Next, you will drive to Arenal, situated in the midst of an unspoiled setting where looming volcanoes and teeming rainforest await. Climb the Arenal Volcano and keep an eye out for some of the most famous bird and animal life in the country! Continue your tour to Monteverde which you will reach by boat. Explore the Cloud Forest and take one step closer to nature in this legendary destination! Your next stop will be in Tamarindo, one of the most famous beach and surf towns in Costa Rica. This is the perfect place to immerse yourself in the local culture and cultivate your adventurous spirit. Head back to San Jose for your final destination on this tour of Costa Rica before you travel home!

Rainforest and jungle visits

Tour Type

Independent Tour

Accommodation

Hotel, Eco Lodge, Lodge, Resort

Age Range

8-99 yrs

Operated in

English

Destinations

San Jose, Tortuguero National Pa

San Jose, Tortuguero National Park, Tamarindo Beach, Arenal Volcano, Tamarindo, Tortuguero, Arenal, Monteverde

Duration13 days

From

USD 1,994

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Super Sales

Premium Peru with Ica Valley - October 2025

No booking fees

Best price guaranteed

Coloured by historic buildings, vibrant wildlife and lush rainforests, Peru is a sight to behold. Join a local leader to discover the Inca, indigenous and modern sides of Peru on an immersive 12-day Premium journey. From the charm of Lima to the wonders of the Ica Valley, the incredible biodiversity of the Amazon Rainforest, the historically rich city of Cusco and the spectacular Inca ruins of Machu Picchu – this adventure takes you straight to the heart of it all. Get a real look at local life and leave with memories to last a lifetime.

Natural landmarks sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Resort

Age Range

15-99 yrs

Operated in

english

Destinations

Cusco, Lima, Machu Picchu, Ica

Cusco, Lima, Machu Picchu, Ica, Puerto Maldonado, Ollantaytambo

Duration12 days

From

USD 6,460

USD 6,266

Saving

USD 194

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Natural Ecuador Adventure 7D/6N - October 2025

No booking fees

Best price guaranteed

Embark on an exhilarating Ecuador expedition blending adventure and nature. Traverse the Amazon Rainforest, marvel at the Andes, and bathe in pristine waterfalls. Encounter diverse wildlife in lush jungles, and explore vibrant indigenous communities. Relish thrilling hikes, local culinary delights, and scenic rides through astounding landscapes. This unforgettable journey offers unique cultural immersion, breathtaking vistas, and thrilling outdoor activities. Experience Ecuador’s raw beauty and vibrant traditions for the ultimate South American adventure.

AdventureTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Quito, Isinlivi, Chugchilán, Banos

Duration7 days

From

USD 1,002

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5-Day Puerto Iguazu Adventure Tour - October 2025

Trip customizable

Best price guaranteed

Get to know one of the 7 World Nature Wonders and World Heritage with this 5-day package to Puerto Iguazu. Explore the jungle and waterfalls from the inside visiting the Argentine side of the park, get the best views from to Brazilian side and make the best adventure activities in the Misiones rainforest. The VACATION PACKAGE IGUAZU ADVENTURE package includes four hotel nights, excursions with tranfers from the city and tranfers from and to the airport

AdventureNational parks

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Iguazu Falls, Misiones, Puerto I

Iguazu Falls, Misiones, Puerto Iguazu, Iguazu Falls National Park

Duration5 days

From

USD 1,652

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4-Day Ushuaia Tour - October 2025

Trip customizable

Best price guaranteed

Enjoy Ushuaia with this 4-day/3-night Vacation Package that includes the main tourist attractions of Ushuaia and its surroundings. We offer roundtrip transfers between the airport and your hotel, as well as during the tours. An expert guide will be by your side for both the tours to Tierra del Fuego National Park and the scenic boat ride. Additionally, we have taken care of your accommodation at a comfortable 4-star hotel, where you'll enjoy a stay in a Standard room complete with a delicious breakfast to start your day

Natural landmarks sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Tierra Del Fuego, Ushuaia

Duration4 days

From

USD 1,272

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All South America Tours in October 2025

Page 39 of 1,732 Trips in South America during October 2025 with 2,427 Reviews

Buenos Aires & Patagonia Family Exploration - October 2025

7-Day Rio de Janeiro & Buzios - October 2025

Santa Cruz Island Diving Adventure 7D/6N - October 2025

North Argentina Highlights - 12 days - October 2025

Lost City of Colombia - 8 days - October 2025

Best of Ecuador and Galapagos Cruise - October 2025

A Taste Of Costa Rica - October 2025

Treasures Of Argentina - October 2025

Picturesque Solo Costa Rica Tour - October 2025

Costa Rican Explorer - October 2025

Premium Peru with Ica Valley - October 2025

Natural Ecuador Adventure 7D/6N - October 2025

5-Day Puerto Iguazu Adventure Tour - October 2025

4-Day Ushuaia Tour - October 2025

Page 39 of 1,732 Trips in South America during October 2025 with 2,427 Reviews

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North America

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Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All South America Tours in October 2025

Page 39 of 1,732 Trips in South America during October 2025 with 2,427 Reviews

Page 39 of 1,732 Trips in South America during October 2025 with 2,427 Reviews