10 Best South America Multiday Tours in October 2025

Sacred Valley Tour & Short Inca Trail 3 Days - October 2025

(2 reviews )

Trip customizable

Best price guaranteed

This travel operator provided us with a two-day trek to Machu Picchu that has to be experienced to be truly understood. Their crew of porters and cook provided exceptional service and meals. David's knowledge was outstanding and his attention to detail in regards to accommodation travel and gear storage was second to none. If you want a first class trekking experience this company should be your first choice.

Sightseeing ToursAdventure

Tour Type

Private and Group Tour

Accommodation

Hotel

Age Range

6-75 yrs

Operated in

english, spanish

Destinations

Inca Trail, Machu Picchu, Sacred

Inca Trail, Machu Picchu, Sacred Valley, Ollantaytambo, Cusco

Duration3 days

From

USD 690

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Galapagos Encounter: Southern Islands (grand Queen Beatriz) - October 2025

22% OFF TODAY

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Galapagos Encounter: Southern Islands (Grand Queen Beatriz) - October 2025

No booking fees

Best price guaranteed

Tick the Galapagos off your list on this week-long sailing voyage that takes in the very best of the southern islands. Rub shoulders with the local wildlife as sea lions, iguanas, giant tortoises and exotic birds of all shapes and sizes go about their daily business. Go snorkelling near mighty manta rays, turtles and tropical fish fill. Experience firsthand the natural, rugged landscapes of the Galapagos and see what Charles Darwin saw when he arrived on the isles more than 180 years ago and go hiking to discover the changing and unique landscapes of this incredible part of the world.

Sailing, yachting and motor boating

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

12-99 yrs

Operated in

english

Destinations

Quito, Baltra Island, Isla Isabe

Quito, Baltra Island, Isla Isabela, Floreana Island, Isla Santa Cruz

22% OFF TODAY

Duration6 days

From

USD 4,140

USD 3,235

Saving

USD 905

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From The Atlantic To The Pacific, Self-drive - October 2025

15% OFF TODAY

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From The Atlantic To The Pacific, Self-drive - October 2025

Trip customizable

Best price guaranteed

Enjoy the highlights of Costa Rica on this eleven-day itinerary, including wonderful jungles, volcano and pristine beaches. This is a country of great natural beauty and every destination has something unique to offer. Whether you are watching the Arenal volcano whilst bathing in hot springs, exploring the dense jungle of Tortuguero or relaxing on the pristine beaches of Tamarindo and the Caribbean Coast, Costa Rica really is a nature lover's paradise.

Active and outdoorAdventure

Tour Type

Private Tour

Accommodation

Hotel, Lodge, Resort

Age Range

6-99 yrs

Operated in

english

Destinations

San Jose, Tortuguero National Pa

San Jose, Tortuguero National Park, Puerto Viejo de Talamanca, Arenal Volcano National Park, Tamarindo

15% OFF TODAY

Duration11 days

From

USD 1,506

USD 1,280

Saving

USD 226

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Tayrona Beaches & Lost City Trek 8D/7N - October 2025

No booking fees

Best price guaranteed

Explore Colombia's breathtaking beauty with Bamba Travel, featuring the ultimate Tayrona Beaches & Lost City adventure. Immerse yourself in lush rainforests, pristine beaches, and ancient ruins. Trek through the Sierra Nevada mountains, traverse jungle trails, and visit indigenous communities. Relax on the stunning white-sand shores of Tayrona National Park, and uncover the mysteries of Ciudad Perdida, the legendary Lost City. This unforgettable experience offers a perfect blend of nature, culture, and history, attracting adventure travelers and nature enthusiasts alike. Book now for an unparalleled Colombian journey.

AdventureWalking toursExplorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Santa Marta, Neguanje, The Lost

Santa Marta, Neguanje, The Lost City Trek, Rio Buritaca

Duration8 days

From

USD 1,412

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Ecuador Volcanoes Adventure 5D/4N - October 2025

No booking fees

Best price guaranteed

Embark on an exhilarating Ecuador adventure exploring stunning volcanoes and pristine landscapes. Experience captivating hikes through Cotopaxi National Park, marvel at the breathtaking Quilotoa Crater Lake, and discover the vibrant cultures of Andean villages. This journey promises unforgettable moments, from horseback riding across scenic highlands to relaxing in natural hot springs. Perfect for nature lovers and thrill-seekers, this tour immerses you in Ecuador's natural wonders and rich cultural heritage. Book now for an extraordinary volcanic escapade!

AdventureTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Quito, Isinlivi, Chugchilán

Duration5 days

From

USD 891

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Arequipa And Colca Canyon, Private Tour - October 2025

15% OFF TODAY

Super Sales

Arequipa And Colca Canyon, Private Tour - October 2025

Trip customizable

Best price guaranteed

Explore Arequipa, the second largest city in Peru, during an awe-inspiring four-day tour. Visit its colonial-style downtown, admire its beautiful churches and catch a glimpse of the pampas outside the city, enjoying the spectacular scenery. Let the graceful flight of the condor entertain you in the Colca Valley and admire the native camelids of the Andes. Join this interesting tour and catch sight of the beautiful nature and interesting Peruvian culture.

Art and architecture

Tour Type

Private Tour

Accommodation

Hotel, Lodge

Age Range

6-99 yrs

Operated in

english, spanish, french, portuguese

Destinations

Arequipa, Colca Canyon

15% OFF TODAY

Duration4 days

From

USD 632

USD 537

Saving

USD 95

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Costa Rica Nature Explorer 8D/7N - October 2025

No booking fees

Best price guaranteed

Discover the natural beauty of Costa Rica with an unforgettable adventure tailored to nature enthusiasts. Immerse yourself in breathtaking landscapes as you explore lush rainforests, majestic volcanoes, and pristine beaches. Enjoy activities like zip-lining, hot springs relaxation, and guided wildlife tours. Spot exotic animals in their natural habitats and savor local cuisine. This tour promises an exhilarating blend of eco-exploration and relaxation, perfect for those seeking an immersive, vibrant Costa Rican experience. Book now for the ultimate tropical getaway!

AdventureExplorerBicycle tours

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

San Jose, Puerto Viejo de Talama

San Jose, Puerto Viejo de Talamanca, La Fortuna

Duration8 days

From

USD 1,224

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Surf Costa Rica (on Request) - October 2025

15% OFF TODAY

Super Sales

Surf Costa Rica (on Request) - October 2025

Trip customizable

Best price guaranteed

This 10-day guaranteed departure tour is the perfect combination of surfing and wildlife adventure. With miles of white sand beaches and unparalleled waves, Costa Rica is a world-class surfing destination. You can relax and surf in places like the tiny village of Jacó with beaches of volcanic sand of cinnamon and Tamarindo where a reputation has been forgotten by the beauty of this city and its beaches. End in Dominical and enjoy the relaxed vibe of this tiny village surrounded by stunning nature.

BeachActive and outdoor

Tour Type

Group Tour

Accommodation

Hotel, Resort

Age Range

6-99 yrs

Operated in

english

Destinations

San Jose, Tamarindo, Jaco, Dominical

15% OFF TODAY

Duration10 days

From

USD 1,948

USD 1,656

Saving

USD 292

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island hopping Galapagos - October 2025

Trip customizable

Best price guaranteed

Experience 4 of the famous Galapagos islands and the unique flora and fauna of the area on this 7-day trip. Discovering Galapagos with our island-hopping tour allows you to really get in touch with the islands. Take advantage of free time after your tours for wandering around the pier, enjoying local food in nice restaurants, observing fisher boots in the harbour, etc. The Islands offer beautiful and unique landscapes as well as a bright range of biodiversity. The most popular animals from the islands are iguanas, sea lions and giant turtles, as well as a range of beautiful birds. The islands also offer great hiking possibilities with views over the whole area. The tour is ideal for people who love to discover even beyond the scheduled excursions. With our daily WhatsApp coaching and special hints for your free time, you'll get to know Galapagos at its best.

National parksWildlife

Tour Type

Group Tour

Accommodation

Hotel

Age Range

1-79 yrs

Operated in

english

Destinations

Quito, Galapagos Islands, Darwin

Quito, Galapagos Islands, Darwin Bay, Playa Ochoa, Tortuga Bay, Bartolome Island

Duration7 days

From

USD 2,190

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Treehouse Lodge, Short Break (on Request) - October 2025

15% OFF TODAY

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Treehouse Lodge, Short Break (on Request) - October 2025

Trip customizable

Best price guaranteed

Enter the green lung of the world and discover the mysteries that the Amazon keeps. Get in touch with nature and live fascinating experiences that let you swim with dolphins, go deep into the jungle, navigate the Amazon in typical wooden canoes of the area, observe nocturnal animals in their habitat and even fish for piranhas; all in the hands of knowledgeable experts and enjoying the fantastic facilities of Tree House Lodge.

AdventureActive and outdoor

Tour Type

Small Group Tour

Accommodation

Lodge, Hotel

Age Range

10-99 yrs

Operated in

english, spanish

Destinations

Iquitos, Lima

15% OFF TODAY

Duration4 days

From

USD 1,291

USD 1,098

Saving

USD 194

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YACHT LA PINTA ORIGIN OF SPECIES ADVENTURE (Mon - Fri) - October 2025

Trip customizable

Best price guaranteed

Yacht La Pinta offers a completely safe travel experience aboard a Galapagos Expedition Yacht in the Enchanted Isles. Each cabin provides not only ample space and comfort but a spectacular view of the Galapagos Islands’ unique landscapes. The ship’s modern feel extends to its hot tub, cardio gym, and sundeck. Land and aquatic activities – from hiking and coastal exploration to kayaking, snorkeling, and even paddleboarding – are complemented by a glass-bottom boat option for curious guests wishing to remain dry. A splendid dining experience featuring delicious, healthy, and top-quality food along with tasty bar options makes the experience all the more enjoyable, whether traveling with friends, family, or by yourself. The entire crew aboard La Pinta will do their utmost to ensure that your Galapagos trip becomes a truly moving and memorable experience.

Expedition toursCruise

Tour Type

Small Group Tour

Accommodation

Ship Cabin

Age Range

6-80 yrs

Operated in

english, spanish

Destinations

Galapagos Islands, Baltra Island

Galapagos Islands, Baltra Island, Sombrero Chino, Isla Santiago, Genovesa Island, Isla Baltra

Duration5 days

From

USD 5,870

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Amantani Homestay & Kayak Experience 2D/1N - October 2025

No booking fees

Best price guaranteed

Experience the captivating culture and stunning landscapes of Lake Titicaca with an authentic Amantani homestay. Paddle through pristine waters on a guided kayak adventure, exploring hidden coves and traditional reed islands. Engage with local families, savoring home-cooked meals and learning ancient traditions. This intimate cultural immersion, set against the backdrop of South America’s highest navigable lake, promises breathtaking views and unforgettable memories. Perfect for travelers seeking an off-the-beaten-path adventure and deep cultural connection.

AdventureTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hostel, Home-stay

Age Range

18-99 yrs

Operated in

english

Destinations

Puno, Lake Titicaca, Amantani

Duration2 days

From

USD 259

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Manaus Amazon Jungle Adventure 3D/2N - October 2025

No booking fees

Best price guaranteed

Embark on an exhilarating journey through the heart of the Amazon, experiencing nature's grandeur up close. Cross mighty rivers, explore protected wildlife havens, and immerse yourself in the rich culture of local caboclos. This compact three-day adventure blends thrilling wildlife encounters with serene jungle explorations.

Rainforest and jungle visits

Tour Type

Small Group Tour

Accommodation

Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

Manaus, Amazon Lodge Tambopata

Duration3 days

From

USD 407

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From the Jungle to the End of the World - October 2025

4.7

(3 reviews )

Trip customizable

Best price guaranteed

My friends and I chose this tour because it visited all the destinations that we wanted to visit: Buenos Aires, Iguazu, Calafate and Ushuaia. It was great because it was the perfect mix between free time and to do the tours that are a must if it is your first time in Argentina. I was in Argentina before and this time I was able to visit the country in a different way with this tour operator. Thanks so much!

Culture shows and excursions

Tour Type

Independent Tour

Age Range

1-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Iguazu Falls, El C

Buenos Aires, Iguazu Falls, El Calafate, Ushuaia, Puerto Iguazu, Perito Moreno Glacier, Tierra Del Fuego National Park, Foz De Iguazú, Beagle Channel Cruise

Duration12 days

From

USD 3,350

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All South America Tours in October 2025

Page 38 of 1,738 Trips in South America during October 2025 with 2,426 Reviews

Sacred Valley Tour & Short Inca Trail 3 Days - October 2025

Galapagos Encounter: Southern Islands (Grand Queen Beatriz) - October 2025

From The Atlantic To The Pacific, Self-drive - October 2025

Tayrona Beaches & Lost City Trek 8D/7N - October 2025

Ecuador Volcanoes Adventure 5D/4N - October 2025

Arequipa And Colca Canyon, Private Tour - October 2025

Costa Rica Nature Explorer 8D/7N - October 2025

Surf Costa Rica (on Request) - October 2025

island hopping Galapagos - October 2025

Treehouse Lodge, Short Break (on Request) - October 2025

YACHT LA PINTA ORIGIN OF SPECIES ADVENTURE (Mon - Fri) - October 2025

Amantani Homestay & Kayak Experience 2D/1N - October 2025

Manaus Amazon Jungle Adventure 3D/2N - October 2025

From the Jungle to the End of the World - October 2025

Page 38 of 1,738 Trips in South America during October 2025 with 2,426 Reviews

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Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All South America Tours in October 2025

Page 38 of 1,738 Trips in South America during October 2025 with 2,426 Reviews

Page 38 of 1,738 Trips in South America during October 2025 with 2,426 Reviews