10 Best South America Multiday Tours in October 2025

Back to the Heights - Great Salt Flats - October 2025

Trip customizable

Best price guaranteed

Our tour Back to the Heights, will allow you to discover the imposing landscape of the Salinas Grandes (Great Salt Flats), located between the provinces of Salta and Jujuy. Let yourself be amazed by this scenario that extends over 200 km2, visit typical villages of the region, travel the famous National Route No 40, and much more!

Natural landmarks sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Salta, Jujuy

Duration1 day

From

USD 215

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Florentino Ameghino Dam Tour - October 2025

Trip customizable

Best price guaranteed

Explore a fascinating hydraulic engineering marvel of beautiful colors and ancient walls. Venture on interpretive hikes along nature trails once used by the indigenous people and immerse in nature

Rainforest and jungle visits

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Puerto Madryn

Duration1 day

From

USD 334

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San Telmo & Mataderos Fairs Tour - October 2025

Trip customizable

Best price guaranteed

Along with a professional tour guide who will accompany you throughout the tour, we will visit two of the most cultural Fairs in the City of Buenos Aires. Let's get to know the history of the place, find beautiful handicrafts, taste the best regional food and watch some folklore show. The excursion includes San Telmo Fair in the morning and then a visit to the famous Fair of Mataderos for lunch at the fair stalls, where we will also enjoy arts festivals and gaucho skill shows, the market, and all the charm of regional products that can be purchased there

City sightseeing

Tour Type

Small Group Tour

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires

Duration1 day

From

USD 142

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Bike Tour Buenos Aires - North Circuit - October 2025

Trip customizable

Best price guaranteed

Get to know Buenos Aires on a different and fun way: biking through multiple neighbourhoods of the city. The North Circuit combines modernity and history, going by the most prestigious districts, such as Puerto Madero, Recoleta and Palermo

Bicycle tours

Tour Type

Small Group Tour

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires

Duration1 day

From

USD 50

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Shore Excursion: Puerto Madryn City Tour and Sea lions - October 2025

Trip customizable

Best price guaranteed

We'll explore the historic old city of Puerto Madryn with it's shopping center, springs, scenic spots and Punta Loma, a settlement of furry sea lions followed by Playa Punta Este and Paraná, where you can see a sunken ship in midwater

City sightseeing

Tour Type

Small Group Tour

Age Range

1-99 yrs

Operated in

english

Destinations

Puerto Madryn

Duration1 day

From

USD 70

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Buenos Aires City Tour & Boat Ride - October 2025

Trip customizable

Best price guaranteed

To see and enjoy Bs As sailing on Rio de la Plata. This is the most complete city tour of Buenos Aires. It will allow you to visit Recoleta, Palermo Woods, Downtown area, San Telmo, La Boca and Puerto Madero. In addition, you can get the best views of the City of Buenos Aires from a whole new perspective: the Rio de la Plata

Boat tours, water sports and marine wildlife

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires

Duration1 day

From

USD 72

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Classic Peru - October 2025

4.8

(33 reviews )

No booking fees

Best price guaranteed

An excellent introduction to Peru. While the highlight of the trip was our visit to Machu Picchu this was a well constructed itinerary with so many highlights covering the landscape, wildlife and history of the country. The accommodation, transport and food were of a high standard, of course with some variations depending on the local environment. The tour leader, Hector, was exceptional, both professional and personable and did his best to maximise our experience. Our concerns with the effect of altitude were needless since every effort was made to ensure full acclimatisation. We also benefited from a lovely group of fellow travellers from the UK and Australia. We flew out a day early so that we could look round Lima and would highly recommend. We also took the Amazon extension staying at the Inkaterra Field station which were enjoyed although there were shortcomings in the itinerary against that described in the brochure. It is also worth considering the optional trips on the second day of Machu Picchu: although it says that this needs to be selected at the time of booking some of the group had been able to book this at a later time. Finally, we have done a number of Explore trips and would rate this one in the highest category.

Active and outdoorRafting

Tour Type

Small Group Tour

Accommodation

Hotel, Guest House, Home-stay

Age Range

16-99 yrs

Operated in

english

Destinations

Cusco, Lima, Machu Picchu, Arequ

Cusco, Lima, Machu Picchu, Arequipa, Chivay, Puno, Lake Titicaca, Sacred Valley

Duration14 days

From

USD 3,080

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Ultimate Galapagos - 10 days - October 2025

No booking fees

Best price guaranteed

GALAPAGOS CRUISE: CENTRAL, SOUTH, EAST & NORTH ISLANDSEncounter sea lion colonies basking on pristine beaches, giant tortoises, iguanas, blue footed boobies and more in the wildlife rich Galapagos islands, on this once in a lifetime 8 day cruise around the remote and beautiful volcanic islands which once inspired Darwin himself. Spending a night before and after the cruise in captivating Quito.

Sailing, yachting and motor boating

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Quito, Isla Santa Cruz, Genovesa

Quito, Isla Santa Cruz, Genovesa Island, Santa Fe Island, San Cristobal Island, Espanola Island, Floreana Island

Duration10 days

From

USD 6,735

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Galapagos Encounters - 7 days - October 2025

No booking fees

Best price guaranteed

GALAPAGOS CRUISE - CENTRAL, NORTH & EAST ISLANDS: Boasting an incredible array of endemic species from the blue-footed booby to the marine iguana, the Galapagos Islands are a true nature lovers’ paradise. Get up close and personal with the resident wildlife on an unforgettable 5 day cruise of these famed islands. Begin and end your adventure with a night in Quito, Ecuador's charming capital.

Cruise

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Quito, Galapagos Islands, Genove

Quito, Galapagos Islands, Genovesa Island, Santa Fe Island, San Cristobal Island

Duration7 days

From

USD 4,585

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Galapagos Discovered - 6 days - October 2025

No booking fees

Best price guaranteed

GALAPAGOS CRUISE - CENTRAL, EAST & SOUTH ISLANDS: Every year the Galapagos Islands tempt throngs of travellers to its shores in search of unique wildlife and other-worldly landscapes. Explore these volcanic islands on a 4-day cruise aboard the M/C Anahi catamaran. Hopping from island to island, discovering what makes it so special. Start and end your Galapagos adventure with a night in captivating Quito, Ecuador's capital.

CruiseWildlife

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Quito, Galapagos Islands, Espano

Quito, Galapagos Islands, Espanola Island, Floreana Island, Isla Santa Cruz

Duration6 days

From

USD 3,895

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Machu Picchu by Train 2D/1N (Sleep in Aguas Calientes) - October 2025

No booking fees

Best price guaranteed

Discover the breathtaking wonder of Machu Picchu with an unforgettable train journey that culminates in exploration. Experience captivating landscapes aboard a scenic train ride, delve into ancient Inca history with guided tours, and unwind in the charming town of Aguas Calientes. This adventure offers an ideal blend of culture, history, and natural beauty. Perfect for those seeking a short, yet immersive experience of one of the world's most iconic archaeological sites.

Getaways and short breaks

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Machu Picchu, Aguas Calientes

Duration2 days

From

USD 483

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Machu Picchu Jungle Trek 4D/3N (Biking Only) - October 2025

No booking fees

Best price guaranteed

Discover an exhilarating adventure in the heart of Peru with an unforgettable biking expedition to Machu Picchu. Pedal through lush jungle landscapes, traverse scenic mountain trails, and marvel at breathtaking ancient ruins on this thrilling journey. Perfect for adrenaline seekers and nature lovers, this tour offers a unique blend of adventure and cultural exploration. Unveil the hidden treasures of the Andes while enjoying guided bike rides and immersive local experiences—an ultimate getaway for your bucket list.

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Machu Picchu, Santa Maria

Cusco, Machu Picchu, Santa Maria, Santa Teresa, Aguas Calientes

Duration4 days

From

USD 636

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Iquitos Amazon Jungle Adventure 5D/4N - October 2025

No booking fees

Best price guaranteed

Discover an unforgettable Amazon jungle adventure in Iquitos, offering immersive wildlife encounters, guided rainforest hikes, and serene boat tours. This tour includes vibrant visits to native communities, exploration of exotic flora and fauna, and fascinating night safaris. Guests can enjoy comfortable accommodations while experiencing the pristine beauty of the Amazon River and its rich biodiversity. Ideal for nature enthusiasts and adventurous travelers looking for a unique, eco-friendly escape in the heart of the Peruvian Amazon.

ExplorerAdventure

Tour Type

Small Group Tour

Accommodation

Lodge, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Amazon Peru, Iquitos, Amazon Lod

Amazon Peru, Iquitos, Amazon Lodge Tambopata, Lima

Duration5 days

From

USD 879

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Iquitos Amazon Jungle Adventure 3D/2N - October 2025

No booking fees

Best price guaranteed

Explore the heart of the Peruvian Amazon with a thrilling jungle adventure in Iquitos. Experience exotic wildlife, guided hikes, and canoe trips through lush rainforests. Marvel at diverse flora and fauna, spot pink river dolphins, and visit indigenous communities. This immersive Amazon journey offers unparalleled opportunities for nature photography and birdwatching. Adventure-seekers and nature enthusiasts will love the unique blend of cultural encounters and breathtaking natural scenery. Book now for a memorable eco-tourism experience in one of the world's most biodiverse regions!

ExplorerAdventure

Tour Type

Small Group Tour

Accommodation

Lodge, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Amazon Peru, Iquitos, Lima

Duration3 days

From

USD 600

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All South America Tours in October 2025

Page 99 of 1,426 Trips in South America during October 2025 with 2,113 Reviews

Back to the Heights - Great Salt Flats - October 2025

Florentino Ameghino Dam Tour - October 2025

San Telmo & Mataderos Fairs Tour - October 2025

Bike Tour Buenos Aires - North Circuit - October 2025

Shore Excursion: Puerto Madryn City Tour and Sea lions - October 2025

Buenos Aires City Tour & Boat Ride - October 2025

Classic Peru - October 2025

Ultimate Galapagos - 10 days - October 2025

Galapagos Encounters - 7 days - October 2025

Galapagos Discovered - 6 days - October 2025

Machu Picchu by Train 2D/1N (Sleep in Aguas Calientes) - October 2025

Machu Picchu Jungle Trek 4D/3N (Biking Only) - October 2025

Iquitos Amazon Jungle Adventure 5D/4N - October 2025

Iquitos Amazon Jungle Adventure 3D/2N - October 2025

Page 99 of 1,426 Trips in South America during October 2025 with 2,113 Reviews

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All South America Tours in October 2025

Page 99 of 1,426 Trips in South America during October 2025 with 2,113 Reviews

Page 99 of 1,426 Trips in South America during October 2025 with 2,113 Reviews