10 Best South America Multiday Tours in May 2026

Lima to Cuzco Express Travel Pass - May 2026

No booking fees

Best price guaranteed

Discover Peru's heart with an exhilarating journey from Lima to Cuzco, ideal for adventurers craving cultural immersion and scenic splendor. Traverse the awe-inspiring Andes, exploring iconic sites like Machu Picchu and the vibrant streets of Cuzco. Engage in diverse activities, from historic city tours to breathtaking hikes amidst sacred valleys. This travel pass promises an unforgettable experience blending ancient history with modern allure, perfect for creating lasting memories in one of South America's most enchanting destinations.

AdventureExplorer

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Lima, Puno, Paracas, Huac

Cusco, Lima, Puno, Paracas, Huacachina, Nazca, Arequipa

Duration12 days

From

USD 779

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Mountains and Glaciers: El Calafate and Torres del Paine - May 2026

(4 reviews )

Trip customizable

Best price guaranteed

My trip to Patagonia was one of the best that I have ever done. The landscapes and the people were something that I would never forget. El Calafate was absolutely beautiful, full of lakes and glaciers. Perito Moreno Glacier is unique and a must if you are travelling to Argentina. I also booked the full day tour to El Chalten, which is very nice but I would have preferred to stay for a few nights in the village to do some of the treks in the area but I did not have many days. I stayed at Hotel Mirador del Lago which has amazing views of Argentino lake. Torres del Paine National Park was equally amazing. Our guide Lucas was incredible and very knowledgeable. Hotel Altiplanico was so beautiful. 100% recommend this tour.

Trekking and HikingExplorer

Tour Type

Independent Tour

Accommodation

Camping, Hotel

Age Range

1-99 yrs

Operated in

english, spanish

Destinations

Torres del Paine National Park

Torres del Paine National Park, Puerto Natales, Perito Moreno Glacier, El Calafate, Punta Arenas

Duration7 days

From

USD 1,980

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Full Costa Rica Explorer 14D/13N - May 2026

No booking fees

Best price guaranteed

Discover the ultimate Costa Rica adventure with vibrant wildlife, lush rainforests, and pristine beaches. Experience breathtaking volcano hikes, thrilling canopy zip-lining, and serene hot springs. Indulge in diverse activities, including exploring Arenal Volcano, Monteverde Cloud Forest, and Manuel Antonio National Park. Encounter exotic wildlife, immerse in local traditions, and savor authentic cuisine. Ideal for nature lovers and adventure seekers, this enriching journey promises unforgettable memories. Book now for an extraordinary Costa Rican escape!

AdventureWildlife

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

San Jose, Monteverde Cloud Fores

San Jose, Monteverde Cloud Forest Biological Preserve, Punta Arenas, Tortuguero National Park, Puerto Viejo de Talamanca, La Fortuna

Duration14 days

From

USD 2,776

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Simply Peru - May 2026

4.7

(12 reviews )

No booking fees

Best price guaranteed

Tour leader was friendly approachable knowledgeable. She took great care of us. Full on tour but that was just what I wanted.

Active and outdoorExplorer

Tour Type

Small Group Tour

Accommodation

Hotel, Guest House

Age Range

16-99 yrs

Operated in

english

Destinations

Cusco, Lima, Machu Picchu, Sacre

Cusco, Lima, Machu Picchu, Sacred Valley, Nazca, Arequipa, Chivay, Puno, Taquile Island

Duration14 days

From

USD 2,080

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14% OFF TODAY

Volcanoes and Galapagos - May 2026

4.9

(28 reviews )

No booking fees

Best price guaranteed

A very varied trip with a full and exciting itinerary. So much to see and such interesting places to visit. All of our guides had extensive knowledge and Myriam in particular went beyond expectation to provide us with a deep insight into the social and economic history of this exciting country. A dream made real!

Active and outdoorWildlife

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

16-99 yrs

Operated in

english

Destinations

Quito, Guayaquil, Sierra Negra

Quito, Guayaquil, Sierra Negra, Isla Santa Cruz, Santa Fe Island, Tortuga Bay, Otavalo, Laguna Cuicocha, Mindo, Cotopaxi National Park, Galapagos Islands, Puerto Villamil

14% OFF TODAY

Duration15 days

From

USD 4,470

USD 3,830

Saving

USD 640

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Cusco / Machu Picchu Tour By Train - May 2026

(1 review )

Trip customizable

Best price guaranteed

If you like to discover new cultures, customs and feel the peace of nature, this unique tour of Cusco and Machu Picchu is all you need. We hope you will join us for an experience that will change your life. Right through the day or night, Cusco is a city that is full of charms and exciting tourist attractions. The mornings are ideal for strolling Inca streets, visiting colonial churches, visiting the legendary San Blas Artisan Quarter (craftsmen) or visiting Inca villages and archaeological remains. In the evenings, the city dresses up with lights, discos, pubs and restaurants, and its main tourist attractions come alive for visitors. The nightlife in Cusco is fun, exciting and unique, and it's certainly enough to satisfy the most demanding national and foreign visitors. The city of Cusco and Machu Picchu are without a doubt experiences you will cherish all your life.

ExplorerSightseeing Tours

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, japanese, portuguese, spanish

Destinations

Cusco, Aguas Calientes, Machu Pi

Cusco, Aguas Calientes, Machu Picchu, Lima

Duration6 days

From

USD 810

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27% OFF TODAY

Super Sales

Inca Discovery - May 2026

(8 reviews )

No booking fees

Best price guaranteed

Enjoyed the trip overall and would recommend to friends and family.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Camping

Age Range

12-100 yrs

Operated in

english

Destinations

Cusco, Lima, Ollantaytambo, Inca

Cusco, Lima, Ollantaytambo, Inca Trail, Machu Picchu

27% OFF TODAY

Duration8 days

From

USD 1,549

USD 1,126

Saving

USD 423

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Puerto Maldonado Amazon Eco-Lodge 5D/4N (from Puerto Maldonado) - May 2026

No booking fees

Best price guaranteed

Explore the breathtaking Amazon Rainforest on a five-day eco-adventure in Puerto Maldonado. This unforgettable journey includes guided nature walks, exotic wildlife spotting, and a serene lake tour in traditional dugout canoes. Stay in a sustainable eco-lodge, where you'll enjoy delicious local cuisine and learn about rainforest conservation. Witness vibrant bird species and encounter playful monkeys in their natural habitat. Immerse yourself in the heart of the Peruvian Amazon, creating lasting memories amidst stunning biodiversity.

Explorer

Tour Type

Small Group Tour

Accommodation

Lodge, Eco Lodge, Bungalow

Age Range

18-99 yrs

Operated in

english

Destinations

Puerto Maldonado, Amazon Peru, Amazon Lodge Tambopata

Duration5 days

From

USD 745

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Caribbean Coast Adventure 5D/4N - May 2026

No booking fees

Best price guaranteed

Embark on a thrilling Caribbean Coast adventure that immerses you in Colombia's vibrant culture and stunning landscapes. Traverse scenic routes, explore pristine beaches, and delve into the lush Tayrona National Park. Experience rich indigenous heritage at a Wiwa community, and hike through mesmerizing jungle trails. Bask in the crystal-clear waters of Cabo San Juan and savor the local cuisine. Perfect for nature lovers and cultural enthusiasts, this journey offers an unforgettable blend of relaxation and exploration.

AdventureTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Cartagena, Santa Marta

Duration5 days

From

USD 512

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Cuzco Welcome Package 4D/3N - May 2026

No booking fees

Best price guaranteed

Embark on an unforgettable journey through Peru's ancient Inca heart with this Cuzco travel tour. Discover mystic ruins, vibrant markets, and breathtaking sceneries of the Sacred Valley. Experience guided tours to iconic landmarks such as Sacsayhuamán and Qorikancha, and immerse yourself in local culture with a traditional Pachamama ceremony. Enjoy the charm of Cuzco's historic streets, captivating architecture, and cozy accommodations. Perfect for history buffs and adventure seekers alike, this tour offers an immersive exploration of Peru's rich heritage.

Motorcycle toursExplorer

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Chinchero District

Duration4 days

From

USD 279

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Pantanal & Bonito Experience 6D/5N - May 2026

No booking fees

Best price guaranteed

Immerse yourself in the breathtaking beauty of Brazil's Pantanal Wetlands and the enchanting town of Bonito on this six-day journey. Traverse the world's vastest wetlands teeming with diverse wildlife and experience unforgettable activities from piranha fishing to exploring glistening waters. Conclude your adventure with leisure in Bonito, famed for its crystal-clear rivers and vibrant ecosystems.

AdventureWildlifeExplorer

Tour Type

Small Group Tour

Accommodation

Lodge, Hostel, Hotel, Eco Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

Pantanal, Campo Grande, Bonito

Duration6 days

From

USD 1,301

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Super Sales

Peru & the Amazon: Cusco to Lima - May 2026

(3 reviews )

No booking fees

Best price guaranteed

I would do it all over again. There was so much to see and learn, that to do it again, would be just as great and we could even experience more.

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge

Age Range

18-100 yrs

Operated in

english

Destinations

Cusco, Lima, Amazon Jungle

Duration6 days

From

USD 2,699

USD 2,618

Saving

USD 81

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Hiram Bingham Luxury Train to Machu Picchu Full Day Tour - May 2026

(1 review )

Trip customizable

Best price guaranteed

Machu Picchu is Machu Picchu- one of a kind. The staff on the Train were incredible - attentive, talented, funny, and caring

Train toursSightseeing Tours

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Cusco, Machu Picchu

Duration1 hour

From

USD 1,250

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Ecuador - Andes to Amazon - May 2026

4.8

(8 reviews )

No booking fees

Best price guaranteed

This was one of the best "Discovery" tours I have been on with Explore. It felt like a real adventure, with the excursions to the volcanoes Cotopaxi and Chimborazo and the boat trips on the Napo river, a tributary of the Amazon. Our tour leader, Fabian, and driver, William, were both excellent. The accommodation was generally very good, with the exception being the Riobamba hotel. I find the comments by a previous reviewer about the current power outages in Ecuador to be absurd. The outages were a mild inconvenience (to us - although I pity the Ecuadorian people) but there were absolutely no security or food safety issues as a result. When I travel in (e.g.) South America I don't expect everything to be just like it is in my cosy Western European home! My one criticism of this trip is that there were far too many shopping stops that were thinly disguised as "cultural visits" - I counted at least ten of these. The number should be at least halved. I mean, what on earth do painted balsa wood parrots have to do with the culture of Ecuador? Or carved nut kernels, for that matter?

Active and outdoorExplorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

16-99 yrs

Operated in

english

Destinations

Quito, Guayaquil, Riobamba, Cuen

Quito, Guayaquil, Riobamba, Cuenca, Otavalo, Peguche, Cotopaxi National Park, Tena, Misahualli, Misicocha, Banos

Duration14 days

From

USD 2,760

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All South America Tours in May 2026

Page 7 of 417 Trips in South America during May 2026 with 956 Reviews

Page 7 of 417 Trips in South America during May 2026 with 956 Reviews

Lima to Cuzco Express Travel Pass - May 2026

Mountains and Glaciers: El Calafate and Torres del Paine - May 2026

Full Costa Rica Explorer 14D/13N - May 2026

Simply Peru - May 2026

Volcanoes and Galapagos - May 2026

Cusco / Machu Picchu Tour By Train - May 2026

Inca Discovery - May 2026

Puerto Maldonado Amazon Eco-Lodge 5D/4N (from Puerto Maldonado) - May 2026

Caribbean Coast Adventure 5D/4N - May 2026

Cuzco Welcome Package 4D/3N - May 2026

Pantanal & Bonito Experience 6D/5N - May 2026

Peru & the Amazon: Cusco to Lima - May 2026

Hiram Bingham Luxury Train to Machu Picchu Full Day Tour - May 2026

Ecuador - Andes to Amazon - May 2026

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All South America Tours in May 2026

Page 7 of 417 Trips in South America during May 2026 with 956 Reviews

Page 7 of 417 Trips in South America during May 2026 with 956 Reviews