10 Best South America Multiday Tours in April 2027

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Epic South America - April 2027

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Experience the full spectrum of South America on this epic 39-day adventure – the perfect way to forge lifelong connections. Follow in the footsteps of ancient people on the Inca Trail in Peru, drive past volcanoes, lakes, llamas and flamingos in the Atacama Desert and marvel at the might of Iguazu Falls. Spend nights on an estancia (farm) in Uruguay and at a homestay on Lake Titicaca, sample Argentinian barbecue in Buenos Aires and roam through the Amazon jungle. With like-minded travel companions and a local leader providing recommendations at every stop, this’ll be a South American expedition like no other.

Adventure

Tour Type

Small Group Tour

Accommodation

Camping, Home-stay, Hotel, Lodge

Age Range

18-35 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Cusco, Pun

Rio de Janeiro, Lima, Cusco, Puno, Amantani, La Paz, Uyuni, Salar De Uyuni, San Pedro De Atacama, Amazon Jungle, Salta, Buenos Aires, Montevideo, Estancia, Iguazu Falls, Paraty, Iguazu Falls, Ilha Grande, Ollantaytambo, Inca Trail

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Duration39 days

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Sao Paulo, Rio de Janeiro & Iguazu Falls - April 2027

Trip customizable

Best price guaranteed

Embark on an unforgettable 9-day journey through Brazil’s most iconic destinations: São Paulo, Rio de Janeiro, and Iguazu Falls. Start your adventure in São Paulo, Brazil's vibrant financial hub and cultural capital, where the bustling streets are alive with diverse culinary delights, world-class museums, and eclectic neighborhoods. Next, head to Rio de Janeiro, a dazzling coastal city renowned for its stunning beaches—Copacabana and Ipanema—the awe-inspiring 38-meter-high Christ the Redeemer statue atop Corcovado Hill, and the panoramic views from Sugar Loaf Mountain, accessible via thrilling cable car rides. Your journey culminates at the breathtaking Iguazu Falls, a natural wonder straddling the border between Brazil and Argentina. Marvel at the sheer power and beauty of 275 individual waterfalls, with the tallest, the 80-meter Devil’s Throat, offering an unforgettable spectacle. Iguazu Falls is truly one of the seven natural wonders of the world and a must-visit on any South American itinerary. This tour promises a perfect blend of urban excitement, natural beauty, and cultural immersion, showcasing the very best of Brazil’s diverse landscapes and vibrant cities.

Rainforest and jungle visits

Tour Type

Independent Tour

Age Range

1-79 yrs

Operated in

english, spanish

Destinations

Iguazu Falls, Sao Paulo, Rio de

Iguazu Falls, Sao Paulo, Rio de Janeiro, Iguazu Falls National Park, Foz De Iguazú, Foz Do Iguacu, Puerto Iguazu

Duration9 days

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Amazon Survival Experience - April 2027

Trip customizable

Best price guaranteed

Experience the heart of the Amazon with an immersive expedition into the Mamori River region, where the jungle's wonders await. Begin your adventure with a reception in Manaus and a journey to the majestic Meeting of the Waters, where the Negro and Solimões rivers converge to form the Amazon River. Explore local markets and marvel at the vibrant landscapes as we travel to the Amazon Turtle Lodge, your base for the upcoming days. Settle into the lodge with a delicious Amazonian lunch and get acquainted with the area before embarking on a multi-day jungle survival experience. You'll navigate waterways, set up camp along the riverbank, and learn essential survival techniques from expert guides. As you explore the dense rainforest, you'll encounter the rich Amazonian flora and fauna, from the morning chorus of birds to the thrilling nocturnal sounds and sights. Each day offers new adventures, including jungle treks, fishing, wildlife observation, and breathtaking sunsets. Paddle through hidden river channels, spot monkeys, sloths, and dolphins, and immerse yourself fully in the Amazon's natural beauty. Conclude your journey with a peaceful return to Manaus, carrying memories of an unforgettable Amazon experience.

Eco toursExpedition tours

Tour Type

Group Tour

Age Range

1-79 yrs

Operated in

English

Destinations

Amazon Brazil, Manaus, Amazon Lodge

Duration8 days

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Colombian Explorer: Medellín Nights & Tayrona National Park - April 2027

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Colombian Explorer: Medellín Nights & Tayrona National Park - April 2027

(3 reviews )

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Loved every moment. I had never solo traveled before but after doing g adventures it doesn’t really feel like you are by yourself.

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel, Villa

Age Range

18-39 yrs

Operated in

english

Destinations

Cartagena, Medellin, Minca, Palo

Cartagena, Medellin, Minca, Palomino, Tayrona National Park, Santa Marta

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Duration10 days

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14 Day Andean Cultures Ecuador - April 2027

Trip customizable

Best price guaranteed

On this fascinating 14-day journey through the heart of Ecuador, you will be immersed in a tapestry of landscapes and rich cultures. Start your adventure in the historic city of Quito, where you'll explore the enchanting Middle of the World Monument. Continue to Otavalo, where vibrant markets and indigenous communities offer a glimpse of Ecuador's diverse heritage. Hike through the scenic wonders of Cuicocha and Cotacachi and experience the warmth of communities such as San Rafael, Peguche and San Pablo. Visit the vibrant Mercado Otavalo, full of local colours and flavors. Head to Papallacta where the hot springs await for a day of activities, then stay at Hakuna Matata Lodge for a delicious maito tasting. Explore the natural beauty of Parrot Claylick, Yanacocha and Macas, and attend a traditional ceremony in Guamote. Immerse yourself in the bustling market of Guamote before heading to Riobamba. Marvel at the grandeur of Chimborazo on a full-day adventure before spending the night in Latacunga. Visit the picturesque towns of Zumbahua, Quilotoa and Chugchilan, each with its own unique charm. Continue your journey through Cienega, Cotopaxi and finish your unforgettable experience back in Quito for your departure. This 14-day itinerary promises a perfect blend of nature, culture and adventure, creating lasting memories of Ecuador's breathtaking landscapes and cultural treasures.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Hut, Lodge

Age Range

18-80 yrs

Operated in

english, spanish

Destinations

Quito, Otavalo, Guamote, Chimbor

Quito, Otavalo, Guamote, Chimborazo, Zumbahua, Colonial Valladolid, Hakuna Matata, Macas, Latacunga

Duration14 days

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Costa Rica Experience - April 2027

Trip customizable

Best price guaranteed

Enjoy the best of Costa Rica with this special multiday vacation package visiting San José city, Arenal Volcano, La Fortuna and Potrero Beach. This package includes a great mix of nature and adventure tours, high quality hotels, deluxe transportation services and professional tour guides. Hike to the base of La Fortuna waterfall and swim in the cristal water river. Later, relax at the world´s class Hot Springs complex of Baldi Hot Springs and taste a delicious buffet lunch. Customize the trip with your preferred tour in Arenal Volcano from a vast list of options Enjoy the beautiful drive from Arenal Volcano to the North Pacific coast till arrival to Potrero Beach. Relax at the deluxe boutique Nammbu Hotel and enjoy the beach and the beautiful facilities this hotel has to offer.

AdventureHot springsVolcanoes

Tour Type

Private Tour

Accommodation

Hotel

Age Range

1-90 yrs

Operated in

english, spanish

Destinations

Guanacaste, San Jose, La Fortuna

Guanacaste, San Jose, La Fortuna, Arenal, Playa Potrero

Duration8 days

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Ausangate lodge to lodge trek - April 2027

Trip customizable

Best price guaranteed

A five-day breathtaking trek in the Cordillera Vilcanota, on a route we call the “The trail of the Apu” located in close proximity to the highest sacred mountain in the Cusco region, Mt. Ausangate. The Apu Ausangate is the bearer of life and the guardian of one of the most pristine mountain ecosystems in the world. The trek is accompanied by llamas and horses that will carry our gear. These are owned by shepherds of the native community of Chillca who are proud to share their land with us, as well as the Spirit of their inspiring world. On our hikes and in our unique Andean lodges, daily meals will be prepared by experienced chefs who will introduce you to a great variety of delicious Peruvian dishes and produce, and for your entertainment: authentic vernacular music, played by local inhabitants, will liven up some of our evenings at the "tambos."

Trekking and Hiking

Tour Type

Private Tour

Accommodation

Eco Lodge, Lodge

Age Range

12-79 yrs

Operated in

english, french, german, spanish

Destinations

Cusco, Ausangate Trek, Chillca

Cusco, Ausangate Trek, Chillca, Machuracay, Anantapata, Huampococha

Duration5 days

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Humantay Lake Full Day Hike - April 2027

Trip customizable

Best price guaranteed

We start early in the morning (around 5:00 am) when your tour guide and a driver will pick you up from your hotel. The first stop of the day will be at Mollepata where you will have a breakfast. Then continue your journey to Soraypampa. Take some rest and prepare yourself for the uphill hike to reach the highest point of the trail. Along the way, you will travel across wonderful landscapes surrounded by mountains. Enjoy surreal views of Humantay Lake (4300 masl) and its surrounding mountains and glaciers. Then get into your transport and drive back to Cusco where you will reach at around 5:00 pm.

Natural landmarks sightseeing

Tour Type

Private Tour

Accommodation

Hotel

Age Range

15-60 yrs

Operated in

english, spanish

Destinations

Cusco, Humantay

Duration1 day

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Patagonia: Turquoise Lakes & Torres Del Paine - April 2027

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Patagonia: Turquoise Lakes & Torres del Paine - April 2027

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Ready to unplug and dive headfirst into the rugged, remote wilderness of Patagonia? This 9-day adventure is your ticket to glacier views, epic hikes, and full-on freedom. You'll trek jaw-dropping trails in Torres del Paine, El Chaltén, and Glacier National Park, with plenty of time to explore on your own too. Think snow-dusted peaks, turquoise lakes that look photoshopped, and fresh air that'll shake off your everyday stress. Camp under the stars, chase unforgettable views, and hit reset with a crew of new friends who are just as stoked as you are. Patagonia isn’t just a place—it’s a feeling. And trust us, it hits different when you’re out there living it.

Explorer

Tour Type

Small Group Tour

Accommodation

Camping, Hostel, Hotel, Tent

Age Range

18-39 yrs

Operated in

english

Destinations

El Calafate, Puerto Natales, Ser

El Calafate, Puerto Natales, Serrano Camp, Laguna Azul, El Chaltén

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Duration9 days

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Bonito Experience - April 2027

Trip customizable

Best price guaranteed

This Bonito trip will take you to one of the most beautiful places in Brazil! Bonito is considered one of the country’s top ecotourism destinations, perfect for those seeking deep contact with nature. The small town of Bonito is approximately 300 km from Campo Grande, the capital of Mato Grosso do Sul. It is also close to Paraguay (about 135 km), which influences the local culture. Another famous destination near Bonito is the Pantanal, making both regions transition areas between the Atlantic forest and the Cerrado. Tourism in Bonito encourages and seeks preservation and conservation, and all attractions are visited with a local guide and there is a limit of daily visitors. Explore crystal-clear rivers, caves, grottoes, rich marine life, and wildlife. Take hikes in the middle of nature, venture on exciting tours like rappelling, or relax by a waterfall. Keep scrolling the page to access our Bonito travel packages and book your next unforgettable experience!

Eco toursAdventure

Tour Type

Private Tour

Age Range

1-99 yrs

Operated in

english, portuguese, spanish

Destinations

Bonito, Campo Grande

Duration5 days

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Pantanal & Amazon Wildlife - April 2027

Trip customizable

Best price guaranteed

Visit two extraordinary natural regions with this unique nature package. First, embark on a Pantanal wildlife experience, an unforgettable adventure into the world’s largest floodplain! Cruise through winding rivers, ride horseback across open plains, go on thrilling night safaris, and fully immerse yourself in the stunning landscapes of the Pantanal. Then, get to know the world’s largest tropical forest and its rivers in an outdoor experience like you’ve never imagined on an Amazon Rainforest sustainable experience! This Panatal is a dream destination for ecotourism enthusiasts, outdoor adventurers, and nature lovers alike. The Pantanal’s rich diversity of wildlife and plants will surround you at every turn, offering a chance to connect deeply with nature. Picture yourself up close with exotic animals and vibrant plant life—an experience unlike any other! The Pantanal is a vast and extraordinary region spanning parts of Brazil, Bolivia, and Paraguay. In Brazil, it covers the southern part of Mato Grosso, and the northwest of Mato Grosso do Sul. Recognized by UNESCO as both a Natural and World Heritage Site and a Biosphere Reserve, this biome is shaped by the Amazon, Cerrado, and Atlantic Forest ecosystems. In the Amazon, discover Manaus and its history in a tour of the largest city in the region and its attractions. Visit the heart of the jungle and stay in a jungle lodge with all the infrastructure you need to enjoy your trip to the Amazon with the utmost comfort and safety. Explore the forest and admire the vegetation of the Amazon and the rivers along with local guides, who will share riverside culture and the secrets of the jungle. Enjoy the opportunity to observe how much life there is in the world’s largest forest on a journey full of learning! Even better? This travel package is curated so you can explore the area safely and exclusively, and it is customizable! Simply consult with our travel agents to create your ideal itinerary! Keep scrolling the page for more information on our packages, and book your next unforgettable trip!

Eco toursAdventure

Tour Type

Group Tour

Age Range

1-99 yrs

Operated in

English

Destinations

Pantanal, Amazon Brazil, Manaus

Pantanal, Amazon Brazil, Manaus, Amazon Lodge, Tracajá

Duration10 days

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Chapada dos Veadeiros Experience - April 2027

Trip customizable

Best price guaranteed

Nattrip's Chapada dos Veadeiros tour offers you the opportunity to discover the "Cradle of Waters" of the Central-West region of Brazil, as this area of the cerrado is known. You will visit waterfalls and viewpoints in the Chapada dos Veadeiros National Park and its surroundings. This itinerary and package are designed for nature lovers and outdoor activity enthusiasts! Ideal for families, groups of friends, couples, and solo travelers. Chapada dos Veadeiros, located in Goiás, is considered a Biosphere Reserve by the UN. Its biome and water abundance make this place unique. In this package for Chapada dos Veadeiros, you will get to know and learn about the region, and visit its main attractions, such as the Vale da Lua (Moon Valley). During this trip to Chapada dos Veadeiros, you will stay in Alto Paraíso. Your transfer to the accommodation, guided tours, entrance fees, and transportation to the attractions are included. Scroll down to the itinerary section for more details.

Eco toursAdventure

Tour Type

Group Tour

Age Range

1-99 yrs

Operated in

English

Destinations

Bonito, Brasília, Raizama, Cario

Bonito, Brasília, Raizama, Cariocas, Saltos Do Rio Preto

Duration5 days

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Santiago To Buenos Aires: Volcanos, Valleys & The Lake District - April 2027

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Santiago to Buenos Aires: Volcanos, Valleys & the Lake District - April 2027

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Pack your bags and get ready to bounce through South America on this 12-day ride full of wild nature, epic nights, and laid-back lake vibes. Start in Santiago and hop an overnight bus to Pucón, where volcanoes, hot springs, and endless adventure await. Cruise through Chile’s dreamy Lake District with a chill stop in Puerto Varas, then cross into Argentina to explore the outdoorsy paradise of Bariloche. Hike, bike, or just soak it all in — your pace, your way. Wrap things up in buzzing Buenos Aires with tango, steak, and one last big night out. This is South America in full colour, and you’re living it large.

Explorer

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-39 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Pucon, P

Buenos Aires, Santiago, Pucon, Puerto Varas, San Carlos de Bariloche

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Duration12 days

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Costa Rica To Panama: Surf, Treks & Starry Skies - April 2027

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Costa Rica to Panama: Surf, Treks & Starry Skies - April 2027

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Ready to bounce from beach to jungle to crater town? This 13-day trip kicks off in Costa Rica and cruises into the wild beauty of Panama, where laid-back vibes meet epic adventure. Chill out on the Caribbean coast in Puerto Viejo, snorkel through starfish-studded waters in Bocas del Toro, and hike cloud forest trails to hidden waterfalls in Boquete. You’ll get up close with local culture, learn how chocolate is made from the source, and hang out in Valle de Antón — an actual town inside a volcanic crater. Wrap it up with a night out in Panama City, and you’ve got a Central American escape that’s anything but basic.

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Hostel, Hotel

Age Range

18-39 yrs

Operated in

english

Destinations

Panama City, San Jose, Valle De

Panama City, San Jose, Valle De Antón, Puerto Viejo de Talamanca, Bocas Del Toro, Boquete

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Duration13 days

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South America Tours in April 2027

Page 11 of 618 Trips in South America during April 2027 with 2,945 Reviews

Page 11 of 618 Trips in South America during April 2027 with 2,945 Reviews

Epic South America - April 2027

Sao Paulo, Rio de Janeiro & Iguazu Falls - April 2027

Amazon Survival Experience - April 2027

Colombian Explorer: Medellín Nights & Tayrona National Park - April 2027

14 Day Andean Cultures Ecuador - April 2027

Costa Rica Experience - April 2027

Ausangate lodge to lodge trek - April 2027

Humantay Lake Full Day Hike - April 2027

Patagonia: Turquoise Lakes & Torres del Paine - April 2027

Bonito Experience - April 2027

Pantanal & Amazon Wildlife - April 2027

Chapada dos Veadeiros Experience - April 2027

Santiago to Buenos Aires: Volcanos, Valleys & the Lake District - April 2027

Costa Rica to Panama: Surf, Treks & Starry Skies - April 2027

Europe

Asia

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Africa

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Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

South America Tours in April 2027

Page 11 of 618 Trips in South America during April 2027 with 2,945 Reviews

Page 11 of 618 Trips in South America during April 2027 with 2,945 Reviews