10 Best Santiago Multiday Tours in April 2026

Atacama & the North - 10 Days - April 2026

No booking fees

Best price guaranteed

Get off the beaten track in Chile’s northern reaches with this unique adventure through the Atacama Desert. Kicking off in Santiago discover fascinating museums, lunar-like landscapes of geysers and rock formations, pre-Hispanic ruins and gigantic geoglyphs, mammoth copper mines and abandoned ghost towns with plenty of natural beauty to boot.

Art and architecture

Tour Type

Private Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Santiago, Arica, San Pedro De At

Santiago, Arica, San Pedro De Atacama, Atacama Desert, El Tatio, Iquique, Putre

Duration10 days

From

USD 7,015

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Grand South America - April 2026

(1 review )

No booking fees

Best price guaranteed

was a great tour director made sure about everyone needs

City sightseeing

Tour Type

Group Tour

Accommodation

Hotel, Resort

Age Range

5-99 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Lake Titic

Rio de Janeiro, Lima, Lake Titicaca, Santiago, Valparaiso, Buenos Aires, Pampas, Iguassu National Park, Iguassu National Park, Cusco, Sacred Valley, Machu Picchu, Puno

Duration23 days

From

USD 18,707

USD 18,146

Saving

USD 561

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Premium Highlights of South America - April 2026

No booking fees

Best price guaranteed

Experience the diversity of wonders across Peru, Chile, Argentina and Brazil on a 24-day Premium journey. Be immersed in the ancient culture of the Incas, visit the Amazon Jungle and revel in the magnificent citadel ruins of Machu Picchu. Soak up the energy of Santiago and Buenos Aires’ lively neighbourhoods and sip some of the world’s best wine in Mendoza. At the border with Brazil, experience the magnificent might of Iguazu Falls, before finally arriving in one of the most beautiful cities in the world, Rio de Janeiro. With the guidance of passionate local leaders, you’ll find out South America dances to the beat of its own drum.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Resort

Age Range

15-99 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Santiago

Rio de Janeiro, Lima, Santiago, Valparaiso, Mendoza, Buenos Aires, Puerto Maldonado, Puerto Iguazu, Amazon Lodge Tambopata, Cusco, Ollantaytambo, Machu Picchu

Duration24 days

From

USD 16,960

USD 16,451

Saving

USD 509

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19-Day Journey through South America - April 2026

Trip customizable

Best price guaranteed

This 19 days / 18 nights travel package offers you to travel the most interesting points of Patagonia, along with Brazil, in the most complete way. Departing from the city of Santiago de Chile, we will make an amazing trip through Patagonia, visiting Puerto Natales, Torres del Paine and El Calafate. Then we continue to the Argentine capital, Buenos Aires, known as the "Paris of Latin America"; The next stop will be in the Iguazú Falls, to finally reach one of Brazil biggest cities: Rio de Janeiro. Do not miss this opportunity!

GlaciersNational parks

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro

Duration19 days

From

USD 10,089

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Bolivia in a Week - April 2026

No booking fees

Best price guaranteed

Ready to experience Bolivia's jaw-dropping natural beauty? This spellbinding trip will take you from the heady heights of La Paz through to the mind-bending beauty of the Bolivian salt flats, with spooky train graveyards, colourful flamingos and plenty of fascinating cultural insights along the way. Make sure there's space on your camera roll.

Desert safarisLocal culture

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-35 yrs

Operated in

english

Destinations

Santiago, Cusco, La Paz, Avaroa National Reserve

Duration6 days

From

USD 1,175

USD 1,140

Saving

USD 35

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Patagonian Explorer Cruise - April 2026

Trip customizable

Best price guaranteed

This land and cruise tour will take you to see the marvels of two iconic South American cities and to the Fjords of Tierra del Fuego in Patagonia. Start this adventure in Santiago, a beautiful cosmopolitan city where you will see Santiago’s most important sites like Plaza de Armas, Modena Palace, Santa Lucía Hill and Barrio Lastarria, the latest is famous for the cultural, inherited and gastronomical options. Continue to Punta Arenas from where you will board your cruise to explore Patagonia. During this cruise you will see the fjords of the southern edge of Tierra del Fuego. Sail the Strait of Magellan into the labyrinth of channels from where you will see the highlights and most important sites and glaciers of the region, you will also visit Wulaia Bay and Cape Horn, known as the “End of the Earth”. After this wonderful cruise in Patagonia, you will disembark in Ushuaia from where you will fly to your last stop, Buenos Aires where you’ll have the chance to explore many of the city’s intriguing and varied neighbourhoods and learn about their culture and history before your tour ends.

CruiseCity sightseeing

Tour Type

Independent Tour

Accommodation

Hotel, Ship Cabin

Age Range

8-99 yrs

Operated in

English

Destinations

Buenos Aires, Punta Arenas, Ushu

Buenos Aires, Punta Arenas, Ushuaia, Wulaia Bay, Pia Glacier, Cóndor Glacier, Santiago

Duration6 days

From

USD 3,097

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11% OFF TODAY

Argentina, Atacama Desert & Chile Delights - April 2026

(1 review )

No booking fees

Best price guaranteed

Exploring the southern parts of South America has been great.

Cultural, religious and historic sites

Tour Type

Group Tour

Accommodation

Hotel, Sleeper Bus

Age Range

10-99 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro, Foz Do

Santiago, Rio de Janeiro, Foz Do Iguacu, Paraty, Buenos Aires, San Pedro De Atacama, El Tigre, Mendoza

11% OFF TODAY

Duration13 days

From

USD 2,745

USD 2,445

Saving

USD 300

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Santiago to Patagonia - 14 days - April 2026

No booking fees

Best price guaranteed

Discover Chile in all its glorious natural beauty from the glittering lakes of Puerto Varas, the scenic archipelago of Chiloé, the panoramic views from Punta Arenas and the jagged granite peaks of the Paine massif. Along the way visit traditional fishing villages, observe comical penguins and explore Torres del Paine national park in your way.

Sightseeing ToursWaterfalls

Tour Type

Private Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Santiago, Punta Arenas, Torres D

Santiago, Punta Arenas, Torres Del Paine, Puerto Varas, Peulla, Chiloe National Park, Santiago

Duration14 days

From

USD 8,575

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Lima to Buenos Aires (via Chile) Travel Pass - April 2026

No booking fees

Best price guaranteed

Embark on a captivating South American adventure traversing the vibrant landscapes of Lima, Santiago, and Buenos Aires. This immersive journey takes you through Peru, Chile, and Argentina, offering unique experiences such as exploring the Sacred Valley, witnessing the surreal beauty of the Atacama Desert, and savoring world-renowned Chilean wines. Discover the rich cultural heritage of each city, from Lima's historic center to Buenos Aires' tango-filled streets. Ideal for adventurers and culture enthusiasts seeking an unforgettable travel experience.

City sightseeingLocal culture

Tour Type

Group Tour

Accommodation

Hostel, Hut, Home-stay, Bungalow, Hotel, Lodge, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Lima, Arequipa, Cu

Buenos Aires, Lima, Arequipa, Cusco, Luquina, Puno, Copacabana, Paracas, La Paz, Sucre, Potosi, Uyuni, Candelaria, Polques, San Pedro De Atacama, Calama, Valparaiso, Santiago, Mendoza, Córdoba, Huacachina, Colca Canyon

Duration41 days

From

USD 2,771

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Premium Peru, Chile & Argentina - April 2026

No booking fees

Best price guaranteed

Capture the true essence of South America on an 18-day Premium adventure through Peru, Chile and Argentina. This journey showcases the continent’s diversity of natural beauty, historic wonder and world-class cuisine, passing by the Andes and the Amazon, Mendoza and the majestic Machu Picchu, the Sacred Valley and sultry Santiago, all the way to the Argentinian powerhouse of Buenos Aires. Gain an insight into ancient Inca culture and local communities, indulge in fine food and some of the region’s best wine, and get to the heart of each destination with expert local knowledge at every step.

Natural landmarks sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Resort

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Lima, Santiago, Va

Buenos Aires, Lima, Santiago, Valparaiso, Mendoza, Amazon Jungle, Cusco, Ollantaytambo, Machu Picchu

Duration18 days

From

USD 11,170

USD 10,835

Saving

USD 335

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22% OFF TODAY

Super Sales

Premium Chile & Argentina - April 2026

No booking fees

Best price guaranteed

Against the magnificent backdrop of the Andes Mountains, journey from Santiago to Buenos Aires, taking in all the history, culture and cuisine in between. This nine-day Premium adventure will show you the heart of Chile and Argentina as you stroll the streets of Santiago with a local guide and sip piscos on a rooftop in the historic centre of Valparaiso. Sample some of the world’s best wine in Mendoza, stroll the stylish neighbourhoods of Buenos Aires and discover El Tigre Delta for an adventure to remember. Packed with Exclusive Experiences, historical Feature Stays and with a local leader by your side, you’ll fall for the vibrancy and indulgent atmosphere of this part of the world in no time.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Valparai

Buenos Aires, Santiago, Valparaiso, Mendoza

22% OFF TODAY

Duration9 days

From

USD 6,145

USD 4,769

Saving

USD 1,376

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Essential Colombia to Chile - 21 days - April 2026

No booking fees

Best price guaranteed

GROUP TOUR (FOR AGES 18 - 55): Set out on the ultimate South American journey with this 21 day tour, packed with bucket-list experiences, breathtaking landscapes, and thrilling adventures! Take in Medellin and Bogota, trek through the Andes to the legendary Machu Picchu, take a boat ride on Lake Titicaca, and explore the vibrant streets of La Paz. Cross the otherworldly Uyuni Salt Flats in a 4x4, marvel at flamingo-filled lagoons, and soak in high-altitude hot springs. Finally, chase adrenaline in the Atacama Desert, from cycling in the Lunar Valley to stargazing under one of the clearest night skies on Earth.

Explorer

Tour Type

Group Tour

Accommodation

Camping, Guest House, Hostel, Hotel, Sleeper Bus

Age Range

18-55 yrs

Operated in

english

Destinations

Medellin, Santiago, Machu Picchu

Medellin, Santiago, Machu Picchu, Cusco, Puno, La Paz, Uyuni, San Pedro De Atacama, Santiago, Salento, Cali, Bogota, Inca Trail

Duration21 days

From

USD 9,075

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Andean Discovery - 18 days - April 2026

No booking fees

Best price guaranteed

Discover the highlights of Chile, Bolivia and Argentina on this 18 day private tour, visiting Atacama and the otherworldly Valley of the Moon, Uyuni, the world's largest salt flat and the spectacular Iguazu Falls, before ending in the sultry capital of Buenos Aires.

Explorer

Tour Type

Private Tour

Accommodation

Hotel, Villa

Age Range

18-80 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Santiago

Buenos Aires, Santiago, Santiago, Tupiza, Purmamarca, Salta, Iguazu Falls, San Pedro De Atacama, Laguna Colorada, Uyuni

Duration18 days

From

USD 8,385

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12 Day Buenos Aires, Patagonia and Santiago de Chile - April 2026

Trip customizable

Best price guaranteed

This 12 days package takes you through Argentina & Chile's highlights. You’ll start your tour in Argentina's never-sleeping capital city of Buenos Aires before heading up south to the Patagonia, where you will discover the cities of Bariloche and Puerto Varas. From there, you’ll fly to Santiago de Chile and be marveled by the capital of Chile

City sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-79 yrs

Operated in

english

Destinations

Santiago, San Carlos de Bariloch

Santiago, San Carlos de Bariloche, Puerto Varas, Frutillar, Puerto Montt, Buenos Aires

Duration12 days

From

USD 5,471

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All Santiago Tours in April 2026

Page 3 of 51 Trips in Santiago during April 2026 with 59 Reviews

Atacama & the North - 10 Days - April 2026

Grand South America - April 2026

Premium Highlights of South America - April 2026

19-Day Journey through South America - April 2026

Bolivia in a Week - April 2026

Patagonian Explorer Cruise - April 2026

Argentina, Atacama Desert & Chile Delights - April 2026

Santiago to Patagonia - 14 days - April 2026

Lima to Buenos Aires (via Chile) Travel Pass - April 2026

Premium Peru, Chile & Argentina - April 2026

Premium Chile & Argentina - April 2026

Essential Colombia to Chile - 21 days - April 2026

Andean Discovery - 18 days - April 2026

12 Day Buenos Aires, Patagonia and Santiago de Chile - April 2026

Page 3 of 51 Trips in Santiago during April 2026 with 59 Reviews

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Santiago Tours in April 2026

Page 3 of 51 Trips in Santiago during April 2026 with 59 Reviews

Page 3 of 51 Trips in Santiago during April 2026 with 59 Reviews