10 Best Santiago Multiday Tours in April 2026

Atacama & the North - 10 Days - April 2026

No booking fees

Best price guaranteed

Get off the beaten track in Chile’s northern reaches with this unique adventure through the Atacama Desert. Kicking off in Santiago discover fascinating museums, lunar-like landscapes of geysers and rock formations, pre-Hispanic ruins and gigantic geoglyphs, mammoth copper mines and abandoned ghost towns with plenty of natural beauty to boot.

Art and architecture

Tour Type

Private Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Santiago, Arica, San Pedro De At

Santiago, Arica, San Pedro De Atacama, Atacama Desert, El Tatio, Iquique, Putre

Duration10 days

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Grand South America - April 2026

4.7

(7 reviews )

No booking fees

Best price guaranteed

was a great tour director made sure about everyone needs

City sightseeing

Tour Type

Group Tour

Accommodation

Hotel, Resort

Age Range

5-99 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Lake Titic

Rio de Janeiro, Lima, Lake Titicaca, Santiago, Valparaiso, Buenos Aires, Pampas, Iguassu National Park, Iguassu National Park, Cusco, Sacred Valley, Machu Picchu, Puno

Duration23 days

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Premium Highlights Of South America - April 2026

18% OFF TODAY

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Premium Highlights of South America - April 2026

No booking fees

Best price guaranteed

Experience the diversity of wonders across Peru, Chile, Argentina and Brazil on a 24-day Premium journey. Be immersed in the ancient culture of the Incas, visit the Amazon Jungle and revel in the magnificent citadel ruins of Machu Picchu. Soak up the energy of Santiago and Buenos Aires’ lively neighbourhoods and sip some of the world’s best wine in Mendoza. At the border with Brazil, experience the magnificent might of Iguazu Falls, before finally arriving in one of the most beautiful cities in the world, Rio de Janeiro. With the guidance of passionate local leaders, you’ll find out South America dances to the beat of its own drum.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Resort

Age Range

15-99 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Santiago

Rio de Janeiro, Lima, Santiago, Valparaiso, Mendoza, Buenos Aires, Puerto Maldonado, Puerto Iguazu, Amazon Lodge Tambopata, Cusco, Ollantaytambo, Machu Picchu

18% OFF TODAY

Duration24 days

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19-Day Journey through South America - April 2026

Trip customizable

Best price guaranteed

This 19 days / 18 nights travel package offers you to travel the most interesting points of Patagonia, along with Brazil, in the most complete way. Departing from the city of Santiago de Chile, we will make an amazing trip through Patagonia, visiting Puerto Natales, Torres del Paine and El Calafate. Then we continue to the Argentine capital, Buenos Aires, known as the "Paris of Latin America"; The next stop will be in the Iguazú Falls, to finally reach one of Brazil biggest cities: Rio de Janeiro. Do not miss this opportunity!

GlaciersNational parks

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro

Duration19 days

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Patagonian Explorer Cruise - April 2026

Trip customizable

Best price guaranteed

This land and cruise tour will take you to see the marvels of two iconic South American cities and to the Fjords of Tierra del Fuego in Patagonia. Start this adventure in Santiago, a beautiful cosmopolitan city where you will see Santiago’s most important sites like Plaza de Armas, Modena Palace, Santa Lucía Hill and Barrio Lastarria, the latest is famous for the cultural, inherited and gastronomical options. Continue to Punta Arenas from where you will board your cruise to explore Patagonia. During this cruise you will see the fjords of the southern edge of Tierra del Fuego. Sail the Strait of Magellan into the labyrinth of channels from where you will see the highlights and most important sites and glaciers of the region, you will also visit Wulaia Bay and Cape Horn, known as the “End of the Earth”. After this wonderful cruise in Patagonia, you will disembark in Ushuaia from where you will fly to your last stop, Buenos Aires where you’ll have the chance to explore many of the city’s intriguing and varied neighbourhoods and learn about their culture and history before your tour ends.

CruiseCity sightseeing

Tour Type

Independent Tour

Accommodation

Hotel, Ship Cabin

Age Range

8-99 yrs

Operated in

English

Destinations

Buenos Aires, Punta Arenas, Ushu

Buenos Aires, Punta Arenas, Ushuaia, Wulaia Bay, Pia Glacier, Cóndor Glacier, Santiago

Duration6 days

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36% OFF TODAY

Argentina, Atacama Desert & Chile Delights - April 2026

(1 review )

No booking fees

Best price guaranteed

Exploring the southern parts of South America has been great.

Cultural, religious and historic sites

Tour Type

Group Tour

Accommodation

Hotel, Sleeper Bus

Age Range

10-99 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro, Foz Do

Santiago, Rio de Janeiro, Foz Do Iguacu, Paraty, Buenos Aires, San Pedro De Atacama, El Tigre, Mendoza

36% OFF TODAY

Duration13 days

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Santiago to Patagonia - 14 days - April 2026

No booking fees

Best price guaranteed

Discover Chile in all its glorious natural beauty from the glittering lakes of Puerto Varas, the scenic archipelago of Chiloé, the panoramic views from Punta Arenas and the jagged granite peaks of the Paine massif. Along the way visit traditional fishing villages, observe comical penguins and explore Torres del Paine national park in your way.

Sightseeing ToursWaterfalls

Tour Type

Private Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Santiago, Punta Arenas, Torres D

Santiago, Punta Arenas, Torres Del Paine, Puerto Varas, Peulla, Chiloe National Park, Santiago

Duration14 days

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Lima to Buenos Aires (via Chile) Travel Pass - April 2026

No booking fees

Best price guaranteed

Embark on a captivating South American adventure traversing the vibrant landscapes of Lima, Santiago, and Buenos Aires. This immersive journey takes you through Peru, Chile, and Argentina, offering unique experiences such as exploring the Sacred Valley, witnessing the surreal beauty of the Atacama Desert, and savoring world-renowned Chilean wines. Discover the rich cultural heritage of each city, from Lima's historic center to Buenos Aires' tango-filled streets. Ideal for adventurers and culture enthusiasts seeking an unforgettable travel experience.

City sightseeingLocal culture

Tour Type

Group Tour

Accommodation

Hostel, Hut, Home-stay, Bungalow, Hotel, Lodge, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Lima, Arequipa, Cu

Buenos Aires, Lima, Arequipa, Cusco, Luquina, Puno, Copacabana, Paracas, La Paz, Sucre, Potosi, Uyuni, Candelaria, Polques, San Pedro De Atacama, Calama, Valparaiso, Santiago, Mendoza, Córdoba, Huacachina, Colca Canyon

Duration41 days

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Premium Peru, Chile & Argentina - April 2026

18% OFF TODAY

Super Sales

Premium Peru, Chile & Argentina - April 2026

No booking fees

Best price guaranteed

Capture the true essence of South America on an 18-day Premium adventure through Peru, Chile and Argentina. This journey showcases the continent’s diversity of natural beauty, historic wonder and world-class cuisine, passing by the Andes and the Amazon, Mendoza and the majestic Machu Picchu, the Sacred Valley and sultry Santiago, all the way to the Argentinian powerhouse of Buenos Aires. Gain an insight into ancient Inca culture and local communities, indulge in fine food and some of the region’s best wine, and get to the heart of each destination with expert local knowledge at every step.

Natural landmarks sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Resort

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Lima, Santiago, Va

Buenos Aires, Lima, Santiago, Valparaiso, Mendoza, Amazon Jungle, Cusco, Ollantaytambo, Machu Picchu

18% OFF TODAY

Duration18 days

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18% OFF TODAY

Super Sales

Premium Chile & Argentina - April 2026

No booking fees

Best price guaranteed

Against the magnificent backdrop of the Andes Mountains, journey from Santiago to Buenos Aires, taking in all the history, culture and cuisine in between. This nine-day Premium adventure will show you the heart of Chile and Argentina as you stroll the streets of Santiago with a local guide and sip piscos on a rooftop in the historic centre of Valparaiso. Sample some of the world’s best wine in Mendoza, stroll the stylish neighbourhoods of Buenos Aires and discover El Tigre Delta for an adventure to remember. Packed with Exclusive Experiences, historical Feature Stays and with a local leader by your side, you’ll fall for the vibrancy and indulgent atmosphere of this part of the world in no time.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Valparai

Buenos Aires, Santiago, Valparaiso, Mendoza

18% OFF TODAY

Duration9 days

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South America: La Paz, Santiago & The Uyuni Salt Flats - April 2026

32% OFF TODAY

Super Sales

South America: La Paz, Santiago & the Uyuni Salt Flats - April 2026

(4 reviews )

No booking fees

Best price guaranteed

This tour was full of culture and community. We loved the range of activities offered in the cities and the mining tour was a real highlight, run by ex miners who have an amazing sense of humour!

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Hotel, Resort

Age Range

12-100 yrs

Operated in

english

Destinations

Santiago, La Paz, Sucre, Potosi

Santiago, La Paz, Sucre, Potosi, Uyuni, Salt Flats, San Pedro De Atacama

32% OFF TODAY

Duration11 days

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25% OFF TODAY

Essential Colombia to Chile - 21 days - April 2026

No booking fees

Best price guaranteed

GROUP TOUR (FOR AGES 18 - 55): Set out on the ultimate South American journey with this 21 day tour, packed with bucket-list experiences, breathtaking landscapes, and thrilling adventures! Take in Medellin and Bogota, trek through the Andes to the legendary Machu Picchu, take a boat ride on Lake Titicaca, and explore the vibrant streets of La Paz. Cross the otherworldly Uyuni Salt Flats in a 4x4, marvel at flamingo-filled lagoons, and soak in high-altitude hot springs. Finally, chase adrenaline in the Atacama Desert, from cycling in the Lunar Valley to stargazing under one of the clearest night skies on Earth.

Explorer

Tour Type

Group Tour

Accommodation

Camping, Guest House, Hostel, Hotel, Sleeper Bus

Age Range

18-55 yrs

Operated in

english

Destinations

Medellin, Santiago, Machu Picchu

Medellin, Santiago, Machu Picchu, Cusco, Puno, La Paz, Uyuni, San Pedro De Atacama, Santiago, Salento, Cali, Bogota, Inca Trail

25% OFF TODAY

Duration21 days

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12 Day Buenos Aires, Patagonia and Santiago de Chile - April 2026

Trip customizable

Best price guaranteed

This 12 days package takes you through Argentina & Chile's highlights. You’ll start your tour in Argentina's never-sleeping capital city of Buenos Aires before heading up south to the Patagonia, where you will discover the cities of Bariloche and Puerto Varas. From there, you’ll fly to Santiago de Chile and be marveled by the capital of Chile

City sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-79 yrs

Operated in

english

Destinations

Santiago, San Carlos de Bariloch

Santiago, San Carlos de Bariloche, Puerto Varas, Frutillar, Puerto Montt, Buenos Aires

Duration12 days

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Picturesque Solo Chile Tour - April 2026

Trip customizable

Best price guaranteed

ABOUT THIS TRIP This small-group tour of Chile will show you the most exhilarating sites and breathtaking attractions this country has to offer! From cosmopolitan cities to magnificent deserts, you will fall in love with the beauty and magic of Chile. Begin your tour in Santiago, the capital which is famous for its magnificent mountain views. Learn about the history and culture of the city as you visit the Plaza de Armas and Santa Lucia Hill. Catch a flight to Punta Arenas, from where you will travel to Puerto Natales. Discover the extraordinary beauty of the region as you explore Patagonia with its magnificent mountains, fjords, glaciers, forests, and steppes. From there you will fly to the Atacama and discover the driest desert in the world as you explore the Moon Valley. This is a breathtaking geological wonder which will make you feel like you are walking on the moon! Bask in the beauty of the Andes Mountains and the teeming volcanoes in this otherworldly area, where you will end your tour of Chile. This is a Solo Tour You don't pay single supplement and get a room for yourself!

Explorer

Tour Type

Group Tour

Accommodation

Hotel, Villa

Age Range

8-99 yrs

Operated in

english

Destinations

Santiago, Atacama Desert, San Pe

Santiago, Atacama Desert, San Pedro De Atacama, Puerto Natales

Duration10 days

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All Santiago Tours in April 2026

Page 3 of 50 Trips in Santiago during April 2026 with 91 Reviews

Get a customized trip to Santiago in April 2026

Page 3 of 50 Trips in Santiago during April 2026 with 91 Reviews

Atacama & the North - 10 Days - April 2026

Grand South America - April 2026

Premium Highlights of South America - April 2026

19-Day Journey through South America - April 2026

Patagonian Explorer Cruise - April 2026

Argentina, Atacama Desert & Chile Delights - April 2026

Santiago to Patagonia - 14 days - April 2026

Lima to Buenos Aires (via Chile) Travel Pass - April 2026

Premium Peru, Chile & Argentina - April 2026

Premium Chile & Argentina - April 2026

South America: La Paz, Santiago & the Uyuni Salt Flats - April 2026

Essential Colombia to Chile - 21 days - April 2026

12 Day Buenos Aires, Patagonia and Santiago de Chile - April 2026

Picturesque Solo Chile Tour - April 2026

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Santiago Tours in April 2026

Page 3 of 50 Trips in Santiago during April 2026 with 91 Reviews

Get a customized trip to Santiago in April 2026

Page 3 of 50 Trips in Santiago during April 2026 with 91 Reviews