10 Best Tours and Trips in Panama City in 2025/2026 - Compare Prices

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Costa Rica & Panama Discovery

4

(1 review )

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Get under the surface of Costa Rica and Panama with this 12-day Caribbean adventure. From San Jose to Panama City, you’ll get introduced to some of the most beautiful spots in two Central American countries, with a perfect balance of included activities and free time for your own explorations. You’ll visit the Ngabe-Bugle community on Isla Popa, learn how to make a traditional Caribbean meal, look out for wildlife on a jungle walk, visit a lock along the Panama Canal and soak in the local hotspots in areas seldom travelled. You can't go wrong with your local leader to steer you in the right direction (to the best bars and surf breaks), plus a small group of adventurers to enjoy them with.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Panama City, San Jose, Puerto Vi

Panama City, San Jose, Puerto Viejo de Talamanca, Chitre, Isla Colon, Bocas Del Toro, Boquete

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Duration12 days

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Best of Central America

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Explore incredible worlds above and below the water through some of Central America's best on this 45-day adventure. Amble down the Yucatan Peninsula to the island paradise of Caye Caulker, then cut inland to the lush jungle around Tikal, cruise to the wide river Rio Dulce and end up among the clouds in Panajachel and Antigua. Continue to the relaxing beach vibes of the Pacific Coast of El Salvador, spot colourful birds perched on the historic facades of Suchitoto and explore the historic cities of Leon and Granada in Nicaragua. Stand in the shadow of mighty Arenal Volcano and spot sloths among the canopy of Monteverde, then admire the towns and steamy jungles of Costa Rice and Panama, stopping off at the stunning islands of Bocas del Toro. With plenty of moments to meet the locals and try the region’s varied cuisines, you can’t go wrong on this carefree Central American journey.

WildlifeCity sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel, Hut, Lodge

Age Range

15-99 yrs

Operated in

english

Destinations

Panama City, Playa Del Carmen, R

Panama City, Playa Del Carmen, Rio Dulce, Antigua, Quetzaltenango, Panajachel, Tulum, Copan, Suchitoto, La Libertad, Leon, Granada, Monteverde, La Fortuna, San Jose, Sarapiqui, Puerto Viejo de Talamanca, Bocas Del Toro, Caye Caulker, Boquete, Chitre, San Ignacio, Flores

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Duration45 days

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Amazing Central America

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Get ready for a 27-day adventure through Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica and Panama. From oceans teeming with marine life to tropical forests alive with jungle melodies, this pocket of Central America is truly a natural paradise. You’ll explore the intricately carved structures at Copan, the cloud forests of Monteverde and spend three nights in the island paradise of Bocas del Toro. Sample varied cuisines along the way during cooking lessons with locals, giving you a real insight into the heart and soul of Central America.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Hut

Age Range

15-99 yrs

Operated in

english

Destinations

Panama City, San Jose, Antigua

Panama City, San Jose, Antigua, Monteverde Cloud Forest Biological Preserve, Puerto Viejo de Talamanca, Cahuita National Park, Granada, Monteverde, La Fortuna, Sarapiqui, Copan, Bocas Del Toro, Boquete, Chitre, Suchitoto, El Cuco, Leon

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Duration27 days

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Central American Explorer

4.8

(13 reviews )

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Great trip. Fantastic leader Wonderful experience

Active and outdoorExplorer

Tour Type

Small Group Tour

Accommodation

Hotel, Eco Lodge, Lodge, Villa

Age Range

16-99 yrs

Operated in

english

Destinations

Panama City, Antigua, Rincon de

Panama City, Antigua, Rincon de la Vieja Volcano National Park, Isla De Ometepe, Granada, Leon, San Salvador, Suchitoto, Panama Canal, Copán Ruinas, Boquete, Bocas Del Toro, Sarapiqui, Arenal, Monteverde Cloud Forest Biological Preserve

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Duration25 days

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Cycle Nicaragua to the Panama Canal

4.4

(8 reviews )

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An excellent way to explore Central America on two wheels—what a ride! I loved every segment of the tour. Just a heads-up: you’ll need more than basic cycling skills… and a truckload of grit. Some of the dirt roads, especially the downhills, are the kind that make you suddenly remember every loved one you’ve ever had. Definitely not for the faint-hearted. About the hotels: a few of the one-night stays were… let’s say “character-building.” The stop in Turrialba in particular did not meet even basic standards. Explore, you can do better—please save future cyclists from that experience. Now, about our tour leader, Mike. After ~15 tours across ~20 countries, I’ve finally had a tour led by a real pro athlete. And wow—what a difference. Mike’s professionalism, enthusiasm, ocean-level patience, and that trademark toothy smile made even the toughest (undualating😄）climbs feel manageable. He set the bar so high that my future tours may need oxygen just to reach it. Absolutely recommended. And if you’re lucky enough to get Mike, prepare to have your expectations ruined—in the best possible way.

Active and outdoor

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

16-99 yrs

Operated in

english

Destinations

Panama City, San Jose, Granada

Panama City, San Jose, Granada, Bocas Del Toro, Santiago, Lake Nicaragua, Maderas Volcano, Tilaran, Arenal Volcano, La Fortuna, Turrialba

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Duration14 days

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Ultimate Central America

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Embark on an in-depth, 59-day Central American adventure from Mexico’s capital to the home of the Panama Canal. Pass through Mexico, Belize, Guatemala, El Salvador, Honduras, Nicaragua, Costa Rica and Panama on a small-group journey through remote villages, historic cities, ancient Maya and Aztec ruins, verdant cloud forests and pure Caribbean beaches. Get acquainted with the local cultures, spectacular landscapes and fascinating histories of Central America as you explore the wealth of tradition, spot the range of unusual wildlife, dive into unique underwater worlds and spend time travelling with like-minded people. Did you hear that? Central America is calling – you better Belize it.

City sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel, Hut, Lodge

Age Range

15-99 yrs

Operated in

english

Destinations

Mexico City, Panama City, Palenq

Mexico City, Panama City, Palenque, Merida, Playa Del Carmen, Chetumal, Caye Caulker, San Ignacio, Flores, Rio Dulce, Antigua, Quetzaltenango, Puebla, Panajachel, Copan, Suchitoto, La Libertad, Leon, Granada, Monteverde, La Fortuna, San Jose, Sarapiqui, Oaxaca, Puerto Viejo de Talamanca, Bocas Del Toro, Boquete, Chitre, San Cristobal De Las Casas

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Duration59 days

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Total Central America: Two Months Of Wild

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Total Central America: Two Months of Wild

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Two months. Seven countries. One unforgettable ride. This all-out Central American adventure kicks off in Mexico City with tacos, mole, and big energy — then it’s full speed ahead through mountains, jungles, highlands, beaches, and islands. You’ll snorkel in Belize, boat across Lake Atitlán, crash with a local fam on Nicaragua’s Ometepe Island, and dance the night away in Panama City. Whether you’re soaking in cloud forest vibes in Costa Rica or chilling barefoot on the San Blas Islands, this trip is the ultimate way to see it all. From street eats to off-the-grid retreats, it’s two months of pure adventure — and it’s calling your name.

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Home-stay, Hostel, Hotel, Hut

Age Range

18-39 yrs

Operated in

english

Destinations

Mexico City, Panama City, Bacala

Mexico City, Panama City, Bacalar, Valladolid, Tulum, Playa Del Carmen, Caye Caulker, San Ignacio, Flores, Rio Dulce, Antigua, Panajachel, San Juan La Laguna, Oaxaca, Copan, Suchitoto, La Libertad, Leon, Granada, Isla De Ometepe, Monteverde, La Fortuna, San Jose, Puerto Viejo de Talamanca, Bocas Del Toro, San Cristobal De Las Casas, Boquete, Valle De Antón, San Blas Islands, Palenque

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Duration62 days

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Panama: Sandy Beaches & San Blas Sunsets

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Panama: Sandy Beaches & San Blas Sunsets

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Looking to unplug and drop off the grid in total island style? This 6-day adventure takes you from the buzz of Panama City to the untouched paradise of the San Blas Islands — and trust us, it’s next-level. Start by soaking in the city’s mix of modern energy and historic charm, before setting sail for the Caribbean. Picture crystal-clear water, palm trees swaying over white sand, and zero Wi-Fi to distract you. The San Blas Islands are run by the Indigenous Guna people, giving you the chance to connect with local culture and traditions while living that beachside barefoot dream. No filters needed — this is as real as paradise gets.

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel, Hut

Age Range

18-39 yrs

Operated in

english

Destinations

Panama City, San Blas Islands

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Duration6 days

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Panama City Tours and Trips

Costa Rica & Panama Discovery

Best of Central America

Amazing Central America

Central American Explorer

Cycle Nicaragua to the Panama Canal

Ultimate Central America

Total Central America: Two Months of Wild

Panama: Sandy Beaches & San Blas Sunsets

Create a customized tour to Panama City and Panama

37 Trips in Panama City with 25 Reviews

Costa Rica & Panama Discovery

Best of Central America

Amazing Central America

Central American Explorer

Cycle Nicaragua to the Panama Canal

Ultimate Central America

Total Central America: Two Months of Wild

Panama: Sandy Beaches & San Blas Sunsets

37 Trips in Panama City with 25 Reviews

Costa Rica to Panama: Surf, Treks & Starry Skies

Panama: Craters, Coasts & Highland Mountains

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

Panama City Tours and Trips

Create a customized tour to Panama City and Panama

37 Trips in Panama City with 25 Reviews

37 Trips in Panama City with 25 Reviews