10 Best Panama City Multiday Tours in November 2025

Accommodations

BudgetSimple stays with essential amenities. Typically guesthouses, hostels or hotels rated below 3 stars — clean, no-frills, and great for value-conscious travelers.
Mid-rangeComfortable and reliable 3-star stays. Expect private rooms, en-suite bathrooms, and solid amenities — a great balance between comfort and cost.
PremiumUpscale 4-5 star hotels and lodges. Enjoy high-end service, refined comfort, and premium locations — ideal for travelers seeking extra indulgence.

Panama City Express 5D/4N - November 2025

No booking fees

Best price guaranteed

Experience the vibrant culture and stunning sights of Panama City in this unforgettable adventure. Discover the historic charm of Casco Viejo, marvel at the engineering wonder of the Panama Canal, and explore the lush biodiversity of the Rainforest Discovery Center. This immersive journey offers a perfect blend of modern city life and natural beauty, providing travelers with unique experiences and unforgettable memories. Join us for a diverse and exciting exploration of one of Central America's most captivating destinations.

AdventureWildlifeBicycle tours

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City

Duration5 days

From

USD 1,162

View Tour

Welcome to Panama City 4D/3N - November 2025

No booking fees

Best price guaranteed

Uncover the mystique of Panama City over four captivating days, where vibrant cultures intertwine with the timeless remnants of Casco Viejo. Traverse the enchanting streets and immerse yourself in the living history, intriguing architecture, and bustling local life that define this dynamic region. Each day unveils a new chapter of exploration, inviting you into the heart of Panama's most storied locales.

ExplorerBicycle tours

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City

Duration4 days

From

USD 302

View Tour

Welcome to Panama City 3D/2N - November 2025

No booking fees

Best price guaranteed

Embark on a captivating journey through Panama City, uniting the thrilling energy of the local culture with the historic charm of Casco Viejo. From the moment you arrive, immerse yourself in the tales of ancient streets, the beauty of striking architecture, and the stories of the past that shape today. This three-day jaunt promises a delightful blend of exploration, discovery, and leisure, enveloped within breathtaking sights and vibrant histories.

ExplorerBicycle tours

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City

Duration3 days

From

USD 213

View Tour

Discover the Unseen Panama 13D/12N - November 2025

No booking fees

Best price guaranteed

Discover the mesmerizing fusion of vibrant city life and tranquil coastal paradises in Panama. Journey through historical sites, breathtaking beaches, and rich biodiversity, while uncovering the diverse cultural tapestry of this captivating nation. From Panama City's urban allure to Bocas del Toro's eco-escapades, every day offers a unique adventure amidst stunning landscapes and vibrant culture.

Explorer

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City, Bocas Del Toro, Pla

Panama City, Bocas Del Toro, Playa Venao, Santa Catalina, Boquete

Duration13 days

From

USD 2,038

View Tour

Self-Drive: Panama Adventure & Beach Explorer 15D/14N - November 2025

No booking fees

Best price guaranteed

Embark on an unforgettable Panama adventure with this exhilarating self-drive tour. Explore lush rainforests, stunning beaches, and vibrant local culture. Highlights include wildlife spotting in Soberania National Park, relaxation on the pristine shores of Bocas del Toro, and thrilling zip-lining in Boquete. Discover the wonders of historic Panama City and the engineering marvel of the Panama Canal. Perfect for independent travelers seeking outdoor thrills and serene beach escapades. Experience the ultimate Panama vacation with adventure and relaxation in one package.

AdventureBicycle tours

Tour Type

Private Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City, Boquete, Las Lajas

Panama City, Boquete, Las Lajas, El Valle, Pedasí

Duration15 days

From

USD 1,900

View Tour

All Panama City Tours in November 2025

5 Trips in Panama City during November 2025

Get a customized trip to Panama City in November 2025

5 Trips in Panama City during November 2025

Panama City Express 5D/4N - November 2025

Welcome to Panama City 4D/3N - November 2025

Welcome to Panama City 3D/2N - November 2025

Discover the Unseen Panama 13D/12N - November 2025

Self-Drive: Panama Adventure & Beach Explorer 15D/14N - November 2025

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Panama City Tours in November 2025

5 Trips in Panama City during November 2025

Get a customized trip to Panama City in November 2025

5 Trips in Panama City during November 2025

Panama City Express 5D/4N - November 2025

Welcome to Panama City 4D/3N - November 2025

Welcome to Panama City 3D/2N - November 2025

Discover the Unseen Panama 13D/12N - November 2025

Self-Drive: Panama Adventure & Beach Explorer 15D/14N - November 2025