10 Best Andes Multiday Tours in September 2025

Accommodations

BudgetSimple stays with essential amenities. Typically guesthouses, hostels or hotels rated below 3 stars — clean, no-frills, and great for value-conscious travelers.
Mid-rangeComfortable and reliable 3-star stays. Expect private rooms, en-suite bathrooms, and solid amenities — a great balance between comfort and cost.
PremiumUpscale 4-5 star hotels and lodges. Enjoy high-end service, refined comfort, and premium locations — ideal for travelers seeking extra indulgence.

Uyuni Salt Flats & Desert Adventure 3D/2N (Atacama to Uyuni) - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable journey through the mesmerizing Uyuni Salt Flats, a photographer's dream destination. Explore surreal landscapes, including vibrant desert lagoons, towering volcanoes, and the captivating Train Graveyard. Encounter unique wildlife at Eduardo Avaroa National Reserve, and experience authentic Bolivian culture as you traverse this otherworldly terrain. This adventure offers exclusive guided tours, stunning sunrise and sunset vistas, and immersive experiences that make it a must-do for nature lovers and thrill-seekers. Book now for an unparalleled Atacama adventure!

ExplorerAdventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Uyuni, Atacama Desert, San Pedro

Uyuni, Atacama Desert, San Pedro De Atacama, Uyuni Salt Flat

Duration3 days

From

USD 359

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Uyuni Salt Flats & Desert Adventure 3D/2N (Uyuni to Atacama) - September 2025

No booking fees

Best price guaranteed

Embark on an enthralling journey through Bolivia's mesmerizing salt flats, enchanting flamingo-dotted lagoons, and stunning desert landscapes. Over three days, discover the captivating beauty of the Uyuni Salt Flats, volcanic wonders, and vibrant hues of untouched nature. Indulge in local culture, adventure, and serenity. This trip blends natural wonders with cultural insights, promising an unforgettable exploration.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Uyuni, San Pedro De Atacama, Age

Uyuni, San Pedro De Atacama, Agencha, Huayllajara

Duration3 days

From

USD 364

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Uyuni Salt Flats & Desert Adventure 4D/3N (Atacama to La Paz) - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable Uyuni Salt Flats and Desert Adventure, journeying from Atacama to La Paz. Explore surreal landscapes of Salar de Uyuni, vibrant lagoons, and the enigmatic Dali Desert. Encounter diverse wildlife, and marvel at the stunning contrasts of the world's largest salt flat. Perfect for thrill-seekers and nature lovers, this tour includes guided excursions, comfortable 4x4 rides, and cultural experiences with local communities. Capture breathtaking photos and create lasting memories on this extraordinary adventure.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Atacama Desert, La Paz

La Paz, Atacama Desert, La Paz, Uyuni Salt Flat, Uyuni, San Pedro De Atacama

Duration4 days

From

USD 401

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Bogota to Quito Travel Pass - September 2025

No booking fees

Best price guaranteed

Explore the vibrant cultures and stunning landscapes of South America on this unforgettable journey from Bogota to Quito. Dive into Colombia's rich history in Bogota, marvel at the breathtaking views in Medellin, and soak in the thermal baths of Santa Rosa. Continue with thrilling experiences in Ecuador, from the bustling markets of Otavalo to Quito's architectural wonders. This adventure promises unique experiences, including lush coffee plantations and the captivating beauty of the Andes mountains. Indulge in an exhilarating blend of nature, culture, and adventure!

AdventureActive and outdoor

Tour Type

Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Quito, Bogota

Duration4 days

From

USD 749

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Uyuni Salt Flats & Desert Adventure 4D/3N (La Paz to Atacama) - September 2025

No booking fees

Best price guaranteed

Embark on a mesmerising 3-day exploration of Bolivia's surreal landscapes. From the eerie beauty of the Train Cemetery to the vivid hues of the coloured lagoons, discover natural wonders and cultural treasures across the Uyuni Salt Flats and the breathtaking Andean highlands. Stay in unique accommodations like the Hotel de Sal, wholly constructed from salt, as you journey through this captivating terrain.

Adventure

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, La Paz, San Pedro De Ata

La Paz, La Paz, San Pedro De Atacama, Uyuni, San Juan, Refugio Huayllajara

Duration4 days

From

USD 421

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Iguazu Falls Adventure 4D/3N (Puerto to Foz) - September 2025

No booking fees

Best price guaranteed

Embark on an exhilarating Iguazu Falls adventure, immersing yourself in the awe-inspiring beauty of both the Argentine and Brazilian sides. This remarkable tour offers guided excursions through lush rainforests, up-close encounters with powerful cascades, and breathtaking panoramic views. Stay in comfortable accommodations and enjoy convenient transfers. Experience the magic of the world's largest waterfall system, marvel at diverse wildlife, and savor unforgettable moments on this thrilling South American escapade. Perfect for nature lovers and thrill-seekers alike!

AdventureExplorer

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Foz Do Iguacu, Puerto Iguazu

Duration4 days

From

USD 509

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Lake Titicaca & Isla del Sol Catamaran Experience 4D/3N (Puno to La Paz) - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable South American adventure with a captivating catamaran journey across Lake Titicaca. Experience the awe-inspiring beauty of Isla del Sol, discover vibrant indigenous cultures, and relish breathtaking sunrise views over the Andean peaks. This tour offers immersive excursions, luxurious onboard amenities, and insightful guided tours of ancient Inca sites, including the Sacred Fountain and Pilkokaina Palace. Ideal for culture enthusiasts and nature lovers, this unique travel experience promises a perfect blend of relaxation and exploration. Book now for an unparalleled Bolivian adventure.

AdventureExplorer

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Puno, La Paz, Copacabana

La Paz, Puno, La Paz, Copacabana, Lake Titicaca

Duration4 days

From

USD 1,316

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Iguazu Falls Adventure 3D/2N (Foz to Puerto) - September 2025

No booking fees

Best price guaranteed

Discover the mesmerizing Iguazu Falls on this thrilling travel adventure from Foz do Iguaçu to Puerto Iguazú. Immerse yourself in the natural wonder with guided tours of both Brazilian and Argentine sides, exploring lush rainforests and dramatic waterfalls. Enjoy electric boat rides and panoramic vistas, capturing breathtaking moments. Perfect for nature lovers and adventure seekers, this tour promises unforgettable encounters with one of the world's most iconic natural attractions. Book now for an ultimate Iguazu Falls experience!

AdventureWalking toursExplorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Foz Do Iguacu, Puerto Iguazu

Duration3 days

From

USD 476

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Iguazu Falls Adventure 3D/2N (Puerto to Foz) - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure to the breathtaking Iguazu Falls! Experience the awe-inspiring power of these natural wonders from both the Argentine and Brazilian sides. Delight in guided jungle treks, exhilarating boat rides, and scenic viewpoints offering panoramic vistas. Perfect for nature lovers and thrill-seekers, this tour promises immersive encounters with diverse flora and fauna. Capture mesmerizing photos and create lifelong memories at one of the world's most iconic waterfall destinations. Ideal for those seeking both adventure and natural beauty.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Foz Do Iguacu, Puerto Iguazu

Duration3 days

From

USD 412

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Lake Titicaca & Isla del Sol Catamaran Experience 4D/3N (Cuzco to La Paz) - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable Peru-Bolivia adventure, exploring the breathtaking Lake Titicaca and iconic Isla del Sol aboard a luxurious catamaran. Experience the rich culture of the Uros Floating Islands, marvel at ancient Inca ruins, and immerse yourself in traditional Andean life. This exclusive journey promises stunning landscapes, hands-on cultural encounters, and seamless transitions between must-see destinations, ensuring an exceptional travel experience from Cusco to La Paz. Don’t miss this extraordinary blend of nature, history, and cultural immersion!

Adventure

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, La Paz, Isla Del Sol, Pun

Cusco, La Paz, Isla Del Sol, Puno, La Paz

Duration4 days

From

USD 1,282

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Lake Titicaca & Isla del Sol Adventure 2D/1N (La Paz to Puno) - September 2025

No booking fees

Best price guaranteed

Explore the stunning beauty of Lake Titicaca and the mythical Isla del Sol with Bamba's unforgettable adventure. Immerse yourself in the culture of local communities, hike through ancient Inca trails, and marvel at breathtaking panoramic vistas. Highlights include a captivating boat ride on the world’s highest navigable lake and exploring ancient ruins. Perfect for adventure seekers and cultural enthusiasts, this tour offers an enriching blend of nature and history, ensuring a memorable travel experience in Peru.

AdventureExplorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Puno, La Paz, Isla Del Sol

Duration2 days

From

USD 220

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Lake Titicaca Catamaran 2D/1N (La Paz to La Paz) - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable journey from La Paz to the breathtaking Lake Titicaca. Experience a luxurious catamaran ride across the world’s highest navigable lake, visiting the mystical Sun and Moon Islands. Engage in captivating cultural exchanges with local indigenous communities and explore ancient Incan ruins. Marvel at stunning Andean landscapes, relish delicious traditional cuisine, and enjoy comfortable onboard amenities. This is a perfect adventure for those seeking to blend nature, history, and luxury in one incredible tour.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Lake Titicaca

Duration2 days

From

USD 1,046

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Lake Titicaca Catamaran 2D/1N (Puno to La Paz) - September 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Puno to La Paz with Bamba Travel. Experience the tranquility of Lake Titicaca aboard a luxurious catamaran, immerse yourself in the rich indigenous culture, and explore the enchanting Sun Island. Highlights include guided tours, traditional ceremonies, and breathtaking Andean landscapes. Perfect for culture enthusiasts and nature lovers, this tour promises an all-inclusive experience filled with unique activities and profound insights into the region's heritage. Don't miss this bucket-list journey across South America's iconic lake.

Adventure

Tour Type

Small Group Tour

Accommodation

Ship Cabin

Age Range

18-99 yrs

Operated in

english

Destinations

Puno, La Paz, Lake Titicaca, La Paz

Duration2 days

From

USD 1,246

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Buenos Aires, El Calafate & Iguazu Falls - September 2025

4.5

(4 reviews )

No booking fees

Best price guaranteed

Your arrangements gave us exactly what we wanted. But we were surprised that this was not a group tour as we thought it would be. Each hotel and excursion was separate, as opposed to being with the same group and tour guide the whole time. However, it worked out fine. We especially loved the hotels selected by the tour company because they were centrally located and we could easily walk around the various cities.

Sightseeing ToursAdventure

Tour Type

Group Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Iguazu Falls, El C

Buenos Aires, Iguazu Falls, El Calafate, Perito Moreno Glacier, Puerto Iguazu, Iguazu Falls National Park

Duration10 days

From

USD 1,930

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All Andes Tours in September 2025

Page 2 of 131 Trips in Andes during September 2025 with 53 Reviews

Uyuni Salt Flats & Desert Adventure 3D/2N (Atacama to Uyuni) - September 2025

Uyuni Salt Flats & Desert Adventure 3D/2N (Uyuni to Atacama) - September 2025

Uyuni Salt Flats & Desert Adventure 4D/3N (Atacama to La Paz) - September 2025

Bogota to Quito Travel Pass - September 2025

Uyuni Salt Flats & Desert Adventure 4D/3N (La Paz to Atacama) - September 2025

Iguazu Falls Adventure 4D/3N (Puerto to Foz) - September 2025

Lake Titicaca & Isla del Sol Catamaran Experience 4D/3N (Puno to La Paz) - September 2025

Iguazu Falls Adventure 3D/2N (Foz to Puerto) - September 2025

Iguazu Falls Adventure 3D/2N (Puerto to Foz) - September 2025

Lake Titicaca & Isla del Sol Catamaran Experience 4D/3N (Cuzco to La Paz) - September 2025

Lake Titicaca & Isla del Sol Adventure 2D/1N (La Paz to Puno) - September 2025

Lake Titicaca Catamaran 2D/1N (La Paz to La Paz) - September 2025

Lake Titicaca Catamaran 2D/1N (Puno to La Paz) - September 2025

Buenos Aires, El Calafate & Iguazu Falls - September 2025

Page 2 of 131 Trips in Andes during September 2025 with 53 Reviews

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All Andes Tours in September 2025

Page 2 of 131 Trips in Andes during September 2025 with 53 Reviews

Page 2 of 131 Trips in Andes during September 2025 with 53 Reviews