Panama in 6 Days: 3 Recommended 6-Day Itineraries to Panama

Do you want to spend 6 days in Panama? With our Panama 6-day itinerary recommendations, you can experience the culture at Panama City, nature at Bastimentos National Marine Park and more!

If you’re looking to balance both city-based culture and world-class nature and wildlife during your 6 days in Panama, you’ll want to start in Panama City. Begin by touring the historic center of the capital, where you can climb the cathedral tower for amazing views, visit the Old Panama City Museum, and visit the French Plaza. Next, jump onboard the Pacific Queen for a partial transit along the iconic Panama Canal. Experience the Miraflores Locks firsthand, as well as the Pedro Miguel Locks, the new Centennial Bridge, and the continental divide of the Gaillard Cut. Moving into the nature portion of your trip, get on another boat at Gatun Lake and start your journey to Soberania National Park. Keep a look out for snail kites, howler monkeys, capuchins, green iguanas, and frigate birds before stretching your legs on a short hike. Next, hop on a motorized canoe and journey up the Chagres River to an Embera Indigenous village for the day. Experience traditional dancing and music. After this, return to Panama City, where you can continue your onward journey. See all tours in Panama.

Want to experience three completely different Panamanian vibes in one short six-day trip? Start at the Bocas del Toro archipelago, which is the home of the Bastimentos National Marine Park. Here, spend a full day snorkeling on Red Frog Beach, enjoy a jungle hike in the national park, or visit a local chocolate farm. Next, journey up to the mountain town of Boquete. Known for its amazing coffee, Boquete is also home to the Boquete Tree Trek Eco Park. Spend the day wandering along the Hanging Bridges tour with amazing views of rivers, waterfalls, and Volcan Baru. After this, board a plane to the capital, Panama City. Visit the Panama Canal, where you can see the Miraflores Locks, and watch this engineering marvel at work. Then, you’ll enjoy a half-day city tour, including a guided tour around the Colonial Quarter, with the Cathedral, National Theatre, Plaza de Francia, and more before departing. Describe your ideal 6-day holiday for a customized trip to Panama.

If you are looking for relaxing vibes in Panama, head to the San Blas Islands. Your journey from Panama City to San Blas will involve a 4x4 drive through the jungle, followed by a boat ride to Guasirdub Island. Settle in here and enjoy the white sandy beaches and gorgeous coral reefs. Next, take a boat to Aguja Island, where you can play volleyball with the locals, go for a swim, or work on your tan. Follow this with a trip to Perro Grande and Perro Chico. On Perro Grande, you can kayak or paddleboard around the island or check out the natural pools, which are popular for starfish. Move to Perro Chico, where you’ll relax in a cabana and snorkel around a sunken ship. Next, journey to Yani Island, which you can explore by paddleboard and see small sharks looking for small fish. You can also opt to visit the private island of Masargadup for a more relaxing vibe. Visit Wailudup Island, with its over-water cabanas, for a couple of hours before heading back to Guasirdub Island. Spend your last evening in paradise before journeying back to Panama City to conclude this Panama 6-day itinerary plan.

With 6 days in Panama, you can easily visit three or four key destinations. Combine nature hikes along the Chagres River with historic tours of Panama City with beach relaxation in the Boca del Toro archipelago. If you have longer to spend in Panama, check out our one-week itineraries for some more inspiration. Need a helping hand booking your Panama trip? Our in-country travel experts are ready to help you plan the custom Panama trip of your dreams.

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