Panama in 2 Weeks: 2 Recommended 14-Day Itineraries to Panama

2 weeks in Panama means plenty of time to explore cities like Panama City and nature at Oria Arriba! Check out our recommended 14-day itineraries in Panama for more inspiration.

With this 2 weeks in Panama itinerary, you get to see the best of everything. Start your adventure in Panama City. Embark on a tour and partial transit of the Panama Canal, marveling at the Miraflores Lock, the Pedro Miguel Locks, the Gaillard Cut, and Lake Gatún. Arrive back in the capital, and enjoy a walking tour around the UNESCO World Heritage Center. Built in 1673, you can see historic sites like the National Theater, Plaza de Francia, and the Museum of Old Panama. Next, hit the road to El Valle de Antón, known for its lush greenery and the El Macho waterfalls. You can enjoy a few short hikes here before getting back on the Pan-American Highway to Natá de los Caballeros where you can visit one of the oldest churches in the country. Continue to Parita where you’ll meet a maker of the authentic Diablicos masks and learn about the tradition. Arrive in the beach city of Las Tablas for an afternoon before heading to the small village of Oria Arriba where you’ll visit a sugar plantation and a tobacco plantation to see how this process works. From here, you’ll journey to the stunning mountain town of Boquete. Embark on a hike through the treetops on a hanging bridges tour before visiting a local coffee farm. You can then opt to go zip-lining or white-water rafting in this adventurous paradise. Next up, travel to the gorgeous Bocas del Toro archipelago. Along the way visit the Oreba Chocolate Farm for a tour and tasting before arriving at this island paradise. Embark on a boat tour around the islands before spending your free time surfing at Red Frog Beach, snorkeling at Bahia de Almirante, or relaxing on Starfish Beach, which can be easily reached by bike. Return to Panama City where you’ll be transferred to the airport for your flight home. See all tours in Panama.

If you want to visit two Latin American icons in one trip, consider cruising between Panama and Costa Rica. Arrive in Panama City and transfer to the port city of Colon where you can board your cruise for the next few nights. Enjoy cruising down the Panama Canal from Colon and marvel at what’s been called the 8th wonder of the world. When you reach Panama City, enjoy a shore excursion that takes you around the historic center, including Plaza Bolivar and the Cathedral, before seeing the mighty Miraflores Locks from land. Continue cruising down the Panama Canal until you reach Chiriqui Marine National Park, home to 50 islands and tons of amazing beaches. Grab your snorkel and head for Isla Parida to see the amazing marine life. Next, wander the trails of the La Perica Sloth Garden to meet these slow-moving creatures and learn more about the site’s conservation efforts. Continue onwards to Esquipulas Bird Paradise where you can learn more about the history of Costa Rica and see hummingbirds and butterflies. Arrive at Puerto Caldera and say goodbye to the cruise portion of your trip. Travel up to Monteverde for some time in the iconic cloud forests. Begin with a coffee and chocolate tour, learning about the local farms and factories making these essentials before visiting Selvatura Adventure Park. Known for its hanging bridges, cloud forest trails, wildlife, and zip lines, there is plenty to see and do here. Check out the Savia Bird Tour and Finca Ecológica San Luis to spot gorgeous birdlife before heading to the Tamarindo Peninsula. Go on a Palo Verde bird tour where you can see the American Woodstock, the Roseate Spoonbill, the Boat-billed Heron, as well as howler monkeys and anteaters. Finally, enjoy the Tamarindo Estuary Tour which takes you by boat through Las Baulas National Park, where you’ll travel through mangroves, scoping out monkeys and iguanas, as well as plenty of birds. See all 14-day tours in Panama.

With 2 weeks in Panama, you really can take your time and see a lot. From the heights of mountainous Boquete to the snorkeling paradise of Bocas del Toro, you can get your fill of adventure, nature, and history. Of course, you can also combine your fortnight trip with a visit to vibrant Costa Rica for more wildlife and variety. Looking for a dream Panama tour? Our in-country travel experts can help you create a custom trip to match your interests and needs. Read our seasonal guide to find out the best time to visit Panama.

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