South America Trips and Tours 2025/2026
The best South America trips and multiday tour packages, delivered by top local South America travel specialists. Compare prices and 4690+ reviews.
Page 5 of 102 Trips in South America with 147 Reviews
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Uyuni Salt Flats & Desert Adventure 4D/3N (Atacama to La Paz)
Venture across Bolivia and Chile with the "Uyuni Salt Flats & Desert Adventure 4D/3N (Atacama to La Paz)"—a tour package designed for those who crave otherworldly scenery and cultural immersion. Beginning in San Pedro de Atacama and ending in La Paz, this journey guides you through surreal landscapes: the dazzling Salar de Uyuni, vibrant colored lagoons, and the mysterious Dali Desert.
Travelers seeking awe-inspiring natural beauty will find plenty to marvel at—flamingos, wild llamas, and dramatic rock formations are just some of the highlights. Guided 4x4 excursions provide both comfort and access to remote vistas, while meaningful encounters with local communities add depth to your cultural experience.
A defining feature of this trip is its seamless integration of nature and culture. Capture breathtaking photographs, enjoy comfortable accommodations, and savor authentic Andean cuisine along the way. The relaxed pace makes it perfect for anyone wanting to fully absorb the magic of South America’s high-altitude deserts without rushing.
If you’re looking for a small group tour that offers both adventure and insight, this unforgettable journey from the Atacama Desert to La Paz promises memories to last a lifetime.
Cultural, religious and historic sites
Santiago to Patagonia - 14 days
Chile’s natural splendor unfolds on the ‘Santiago to Patagonia - 14 Days’ tour, guiding you from Santiago’s urban energy to the dramatic peaks of the Paine massif. Explore Puerto Varas’ glittering lakes, the mythical Chiloé archipelago, and Torres del Paine National Park’s jagged beauty. Along the way, visit fishing villages, spot penguins, and soak up panoramic views from Punta Arenas. Designed for seniors and experienced travelers, this private sightseeing trip offers both comfort and adventure. Its standout feature? A comprehensive exploration of Chile’s most breathtaking and varied landscapes.
Sightseeing ToursWaterfalls
Uyuni Salt Flats & Desert Adventure 3D/2N (Atacama to Uyuni)
Set out from San Pedro de Atacama on a three-day guided trip through the spellbinding Uyuni Salt Flats and Bolivia’s high-altitude desert. This adventure-packed tour connects you with the dazzling white expanse of Uyuni, colorful lagoons, ancient volcanoes, and the quirky Train Graveyard. Encounter wildlife at Eduardo Avaroa National Reserve and experience authentic Bolivian culture along the way. With exclusive sunrise and sunset tours, this relaxed journey is tailored for thrill-seekers and landscape photographers eager to capture surreal natural wonders. The tour package’s standout feature is its seamless blend of cultural immersion and out-of-this-world scenery—making it the ultimate Atacama adventure for young adults and experienced explorers alike.
ExplorerAdventure
8-Day Argentina & Patagonia Tour From Buenos Aires: El Calafate & Ushuaia
Embark on a remarkable Patagonian adventure with the 8-Day Argentina & Patagonia Tour from Buenos Aires: El Calafate & Ushuaia. This expertly guided tour package whisks you from the vibrant cityscape of Buenos Aires to the wild landscapes of southern Argentina and Chile. Spend time exploring the urban pulse of the capital before journeying to El Calafate, the gateway to the mesmerizing Perito Moreno Glacier, and then on to Ushuaia, the world’s southernmost city.
Delve deep into Patagonia’s dramatic scenery, where snowy peaks, crystalline lakes, and the unique wildlife of Tierra del Fuego await. Highlights include exploring Los Glaciares National Park and discovering beaver dams amidst stunning natural vistas. Each destination is brought to life through guided natural landmarks sightseeing, with all accommodations, transfers, and meals thoughtfully arranged.
What sets this tour apart is its comprehensive exploration of Patagonia’s diverse landscapes—from icy glaciers to remote forests—delivered in a convenient and enriching itinerary. Ideal for travelers seeking both the thrill of the wild and the comfort of a fully supported group trip.
Natural landmarks sightseeing
Picturesque Solo Chile Tour
From Santiago’s mountain-framed skyline to the lunar landscapes of the Atacama Desert, the "Picturesque Solo Chile Tour" is crafted for experienced travelers eager to discover Chile’s diverse beauty. Over ten relaxed-paced days, explore Santiago’s historic highlights before flying south to Patagonia’s wild fjords, glaciers, and steppes. The journey culminates in the Atacama, where Moon Valley’s surreal scenery awaits. With a guaranteed solo room and small-group camaraderie, this tour package promises both independence and connection. Its standout feature: an expertly guided trip combining Chile’s urban energy, Patagonian wilderness, and otherworldly desert in one seamless adventure—no single supplement required.
Explorer
Atacama & the North - 10 Days
Venture into the lesser-known wonders of northern Chile with "Atacama & the North - 10 Days." Starting in Santiago and ending in Arica, this easy-paced guided tour is ideal for mature travelers who crave off-the-beaten-path exploration. Delve into the lunar landscapes of the Atacama Desert, marvel at El Tatio’s geysers, and uncover ancient geoglyphs and pre-Hispanic ruins. Visit mammoth copper mines and abandoned ghost towns, all while enjoying comfortable hotels and curated experiences. The USP here is the rare opportunity to witness Chile’s northern frontier—an area rich in natural beauty, history, and striking contrasts—away from the typical tourist trails.
Art and architecture
Highlights Of Chile
Let the magic of Chile’s breathtaking landscapes unfold on this 7-day ultra-small group tour, perfectly suited for those who prefer a relaxed, immersive travel style. Begin in Santiago, where dramatic mountain vistas and vibrant districts set the stage for discovery—visit Santa Lucia Hill for panoramic views and explore landmarks like Plaza de Armas. Journey south to Puerto Natales and dive into Patagonia’s legendary beauty, where glaciers, fjords, forests, and sweeping steppes captivate at every turn. The tour concludes amid the untamed wilderness, leaving you with indelible memories. With comfortable accommodations, expert guidance, and thoughtfully arranged transport, this tour package’s unique draw is its ability to seamlessly connect city excitement with the untouched wonders of Patagonia.
Chill outCity sightseeing
4-Day Ushuaia Tour
Experience the magic of Argentina’s southern frontier with the 4-Day Ushuaia Tour, starting and ending in Tierra del Fuego. This sightseeing trip introduces you to the region’s spectacular natural wonders, including the famous Tierra del Fuego National Park and a scenic boat excursion. With comfortable 4-star accommodation, daily breakfast, and expert guides to lead your explorations, you’ll enjoy seamless transfers and insightful commentary every step of the way. The unique selling point of this tour package is its comprehensive coverage of Ushuaia’s must-see attractions, making it ideal for travelers seeking a well-rounded and hassle-free Patagonian adventure.
Natural landmarks sightseeing
Lake Titicaca & isla del Sol Explorer 2D/1N (Cusco to La Paz)
Embark on an unforgettable journey from Cusco to Lake Titicaca, experiencing a captivating blend of history and nature. Begin with an overnight bus ride through the majestic Andes to Puno, where you'll explore the remarkable Uros Islands. These floating marvels, entirely crafted from totora reeds, offer a unique glimpse into the resourceful lifestyle of the Uros people. Discover their traditional practices and the role tourism now plays in their lives, all while enjoying a scenic boat ride on the serene waters of the world’s highest navigable lake.
Bicycle tours
Northern Argentina & Chile Tour
Explore the vibrant cities of Salta and Cafayate, traverse the diverse landscapes of the Puna region and delve into the cultural wonders of Quebrada de Humahuaca with our 10-day partially guided Northern Argentina and Chile Tour.
On this tour, you will have the chance to cross the majestic Andes and explore the arid expanse of the Atacama Desert in Chile, marvel at the famous multicolored hills, serene lagoons and surreal geological formations and discover the desert’s stark beauty and vast open spaces that offer a stark contrast to the lush valleys of Argentina.
Please see our itinerary for more details.
ExplorerDeserts and canyons