10 Best South America Multiday Tours in September 2026

Lima to Rio de Janeiro (Chile & Argentina) Travel Pass - September 2026

No booking fees

Best price guaranteed

Experience the ultimate South American adventure with a travel pass from Peru's vibrant Lima to Brazil's energetic Rio de Janeiro, traversing stunning Chile and Argentina. Discover iconic wonders like Machu Picchu, the Atacama Desert, and Iguazu Falls. Immerse yourself in local culture, savor world-class cuisine, and engage in thrilling activities from wine tasting in Mendoza to tango dancing in Buenos Aires. This unforgettable journey promises diverse landscapes, rich traditions, and unforgettable memories, perfect for avid explorers and cultural enthusiasts.

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hostel, Hut, Home-stay, Bungalow, Hotel, Villa, Guest House

Age Range

18-99 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Arequipa

Rio de Janeiro, Lima, Arequipa, Cusco, Puno, Copacabana, La Paz, Paracas, Sucre, Potosi, Uyuni, Agencha, Polques, San Pedro De Atacama, Salta, Puerto Iguazu, Florianopolis, Sao Paulo, Huacachina, Paraty, Ilha Grande, Nazca, Colca Canyon

Duration46 days

From

USD 3,589

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Super Sales

Classic South America - September 2026

No booking fees

Best price guaranteed

See the sights of Santiago, enjoy wine tasting in Casablanca Valley and get up close with Eva Peron’s famous balcony in Buenos Aires—all on this immersive tour of South America. Step out with a Local Expert in Brazil for a stunning walk past the misty rainbows and thundering gravity of Iguassu Falls—with panoramic views of San Martin Island. In Rio de Janeiro, Enjoy an authentic lunch at a local churrascaria, a traditional Brazilian steakhouse and quintessential Brazilian experience. Across the border in Argentina, Buenos Aires beckons with a once in a lifetime choice to join South America’s Gaucho cowboys for a horseback ride through the rugged wilderness or a guided sojourn around the Estancia, to learn about cattle-raising and life on the ranch.

City sightseeing

Tour Type

Group Tour

Accommodation

Hotel, Resort

Age Range

5-99 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro, Buenos

Santiago, Rio de Janeiro, Buenos Aires, Iguazu Falls National Park

Duration12 days

From

USD 10,598

USD 10,280

Saving

USD 318

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Puerto Maldonado Amazon Superior Lodge 4D/3N (from Puerto Maldonado) - September 2026

No booking fees

Best price guaranteed

Embark on an unforgettable Amazon adventure in Puerto Maldonado, immersing yourself in the heart of the Peruvian rainforest. Stay in a superior lodge and explore the rich biodiversity through guided jungle treks, vibrant wildlife sightings, and thrilling boat rides. Discover hidden lagoons, exotic birds, and unique flora. Experience authentic cultural exchanges with local communities and indulge in sustainable, eco-friendly tourism. Perfect for nature enthusiasts and adventure seekers craving an immersive Amazonian escape.

Rainforest and jungle visits

Tour Type

Small Group Tour

Accommodation

Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

Puerto Maldonado, Amazon Lodge Tambopata

Duration4 days

From

USD 872

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Family Adventure in Patagonia - September 2026

(11 reviews )

Trip customizable

Best price guaranteed

We want to thank you for creating an amazing itinerary with spectacular scenery and wonderful hotels. Additionally, the domestic and international flights, and transfers were seamless and the guides, for the most part, exceeded our expectations. They were knowledgeable and attentive and made us feel extremely comfortable in the foreign environments we experienced along the way. We will not hesitate to recommend you and to anyone interested in visiting your beautiful country.

Natural landmarks sightseeing

Tour Type

Private Tour

Accommodation

Hotel, Tent

Age Range

1-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, El Calafate, Ushua

Buenos Aires, El Calafate, Ushuaia, Tierra Del Fuego National Park

Duration10 days

From

USD 4,575

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Salkantay Trek to Machu Picchu 4D/3N - September 2026

(21 reviews )

No booking fees

Best price guaranteed

The trek was very well organized from the beginning to end. I was quite nervous to do it but the team was very motivating and attentive, which I really appreciated. The guide was very informative and the food was great.

Active and outdoor

Tour Type

Small Group Tour

Accommodation

Camping, Tent, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Salkantay, Cusco, Machu Picchu

Salkantay, Cusco, Machu Picchu, Soraypampa, Colcapampa, Aguas Calientes

Duration4 days

From

USD 758

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Ravines, Valleys & Folklore music - September 2026

(7 reviews )

Trip customizable

Best price guaranteed

All in all, we were really delighted with the service that we received from you. Thanks! Our favourite part of the trip was the week we spent in the North West driving ourselves. We would definitely like to do that again and spend more time in some of the villages and towns. Feedback and thoughts on the various activities and places we stayed and visited: I have written reviews on TripAdvisor for most of them, you can find me under the username fractal if youd like to read them We liked all the hotels we stayed in. Each one was just right for its location and suited us perfectly. If we had to pick, probably our two favourites were Hacienda de Molinos in Molinos and Finca Adalgisa in Chacras de Coria. Hacienda de Molinos had great charm and the food was excellent. We loved our room and would have liked to have spent a couple of days there. The Vinas de Cafayate had great views and the room was nice. The food in their restaurant was also quite good.. The Design Suites Hotel in Salta was great.our room on our first couple of nights was nicer than the room we had when we returned.the first room had a better view. The breakfasts were a little boring. La Comarca in Purmamarca was really nice. It had great views of the mountains and was spacious. One thing we did notice..Argentina is a wine country and yet only one or two of the hotels had wine glasses in the rooms.we had to ask!! The agents on the ground were mostly very good.

Natural landmarks sightseeing

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Salta, Cafayate, Calchaquies Val

Salta, Cafayate, Calchaquies Valley, Calchaqui Valley

Duration5 days

From

USD 1,075

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Beaches And Nature With Santa Teresa - September 2026

15% OFF TODAY

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Beaches And Nature With Santa Teresa - September 2026

(1 review )

Trip customizable

Best price guaranteed

We had a great trip! Accommodation ranged from good to excellent. Breakfasts were included but some early departures resulted in them being missed. Transfers were good and on time. Andres at the tour operator responded quickly to our questions and solved a few problems for us. The itinerary was great. Although Santa Theresa was hard to get to (rough roads, long drive) it was fun to see. You get to see a lot of Costa Rica on this trip.

Active and outdoorBeach

Tour Type

Group Tour

Accommodation

Hotel, Eco Lodge, Lodge, Resort

Age Range

6-99 yrs

Operated in

english, spanish

Destinations

Liberia City, Tamarindo Beach, S

Liberia City, Tamarindo Beach, Sarapiqui, Arenal, Monteverde Cloud Forest Biological Preserve, Samara Beach, Punta Arenas, San Jose, Tortuguero, Tortuguero National Park

15% OFF TODAY

Duration15 days

From

USD 2,742

USD 2,331

Saving

USD 411

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9 Days - The Best of Peru - September 2026

Trip customizable

Best price guaranteed

Join us on this nine-day group tour to discover the historic and natural landmarks of Peru. Starting from Lima, this tour will take you to Cusco, Machu Picchu, Puno and Lake Titicaca before returning back to Lima. Sample the delights of the Peruvian capital city of Lima. Walk on the cobblestone streets of Cusco and see the incredible landscapes of the Sacred Valley of the Incas. Lose yourself among the ruins of Machu Picchu and travel to the spectacular Lake Titicaca, the world's highest navigable lake. And see the Quechua people whose life sways to the rhythm of the quena and the charango. Discover their customs and traditions. Please scroll down to the itinerary section for more details.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Home-stay

Age Range

6-70 yrs

Operated in

english, spanish

Destinations

Cusco, Machu Picchu, Lima, Puno

Cusco, Machu Picchu, Lima, Puno, Lake Titicaca, Aguas Calientes, Luquina

Duration9 days

From

USD 1,222

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Mountains and Glaciers: El Calafate and Torres del Paine - September 2026

(4 reviews )

Trip customizable

Best price guaranteed

My trip to Patagonia was one of the best that I have ever done. The landscapes and the people were something that I would never forget. El Calafate was absolutely beautiful, full of lakes and glaciers. Perito Moreno Glacier is unique and a must if you are travelling to Argentina. I also booked the full day tour to El Chalten, which is very nice but I would have preferred to stay for a few nights in the village to do some of the treks in the area but I did not have many days. I stayed at Hotel Mirador del Lago which has amazing views of Argentino lake. Torres del Paine National Park was equally amazing. Our guide Lucas was incredible and very knowledgeable. Hotel Altiplanico was so beautiful. 100% recommend this tour.

Trekking and HikingExplorer

Tour Type

Independent Tour

Accommodation

Camping, Hotel

Age Range

1-99 yrs

Operated in

english, spanish

Destinations

Torres del Paine National Park

Torres del Paine National Park, Puerto Natales, Perito Moreno Glacier, El Calafate, Punta Arenas

Duration7 days

From

USD 1,980

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Rio de Janeiro to Santiago Travel Pass - September 2026

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Rio de Janeiro to Santiago, exploring South America’s vibrant culture and breathtaking landscapes. Dive into lively Rio’s beaches, marvel at Iguazu Falls’ natural wonders, and revel in Buenos Aires’ rich history. Experience Chile’s scenic beauty in Colchagua Valley and the energetic atmosphere of Santiago. Perfect for thrill-seekers and cultural enthusiasts, enjoy unique excursions including wine tasting and tango dancing lessons. Discover the essence of South America with this curated travel experience.

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro, Floria

Santiago, Rio de Janeiro, Florianopolis, Foz Do Iguacu, Puerto Iguazu, Buenos Aires, Córdoba, Mendoza, Ilha Grande, Paraty, Sao Paulo

Duration21 days

From

USD 1,779

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Full Costa Rica Explorer 14D/13N - September 2026

No booking fees

Best price guaranteed

Discover the ultimate Costa Rica adventure with vibrant wildlife, lush rainforests, and pristine beaches. Experience breathtaking volcano hikes, thrilling canopy zip-lining, and serene hot springs. Indulge in diverse activities, including exploring Arenal Volcano, Monteverde Cloud Forest, and Manuel Antonio National Park. Encounter exotic wildlife, immerse in local traditions, and savor authentic cuisine. Ideal for nature lovers and adventure seekers, this enriching journey promises unforgettable memories. Book now for an extraordinary Costa Rican escape!

AdventureWildlife

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

San Jose, Monteverde Cloud Fores

San Jose, Monteverde Cloud Forest Biological Preserve, Punta Arenas, Tortuguero National Park, Puerto Viejo de Talamanca, La Fortuna

Duration14 days

From

USD 2,776

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Tortuguero National Park Adventure 2D/1N - September 2026

(1 review )

No booking fees

Best price guaranteed

Embark on an awe-inspiring Costa Rica eco-adventure at Tortuguero National Park! Encounter lush rainforests, diverse wildlife, and pristine waterways. Highlights include guided boat tours through serene canals, where you'll spot exotic species like sloths, monkeys, and vibrant toucans. Witness the magical sight of nesting sea turtles on pristine beaches. Immerse yourself in this unparalleled eco-destination, perfect for nature lovers and wildlife enthusiasts. Book your unforgettable tropical getaway today and experience the true essence of Costa Rica!

National parks

Tour Type

Small Group Tour

Accommodation

Eco Lodge, Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

San Jose, Tortuguero National Park

Duration2 days

From

USD 452

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From The Atlantic To The Pacific - September 2026

15% OFF TODAY

Super Sales

From The Atlantic To The Pacific - September 2026

Trip customizable

Best price guaranteed

Enjoy the highlights of Costa Rica on this eleven-day itinerary, including wonderful jungles, volcano and pristine beaches. This is a country of great natural beauty and every destination has something unique to offer. Whether you are watching the Arenal volcano whilst bathing in hot springs, exploring the dense jungle of Tortuguero or relaxing on the pristine beaches of Tamarindo and the Caribbean Coast, Costa Rica really is a nature lover's paradise.

Active and outdoorAdventure

Tour Type

Group Tour

Accommodation

Hotel, Lodge, Resort

Age Range

6-99 yrs

Operated in

english, spanish

Destinations

San Jose, Tortuguero National Pa

San Jose, Tortuguero National Park, Puerto Viejo de Talamanca, Arenal Volcano National Park, Tamarindo

15% OFF TODAY

Duration11 days

From

USD 1,702

USD 1,447

Saving

USD 255

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Ecuador - Andes to Amazon - September 2026

4.6

(11 reviews )

No booking fees

Best price guaranteed

This was a great trip with a good range of experiences, scenery, nature, culture, communities and food. Our guide was very knowledgeable and great at spotting and identifying birds. She judged exactly the right pace for walks and exploring, enabling everyone to participate fully. Ecuador is a wonderful country to visit and I thoroughly enjoyed the trip.

Active and outdoorExplorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

16-99 yrs

Operated in

english

Destinations

Quito, Guayaquil, Riobamba, Cuen

Quito, Guayaquil, Riobamba, Cuenca, Otavalo, Peguche, Cotopaxi National Park, Tena, Misahualli, Misicocha, Banos

Duration14 days

From

USD 2,760

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All South America Tours in September 2026

Page 25 of 1,216 Trips in South America during September 2026 with 3,429 Reviews

Lima to Rio de Janeiro (Chile & Argentina) Travel Pass - September 2026

Classic South America - September 2026

Puerto Maldonado Amazon Superior Lodge 4D/3N (from Puerto Maldonado) - September 2026

Family Adventure in Patagonia - September 2026

Salkantay Trek to Machu Picchu 4D/3N - September 2026

Ravines, Valleys & Folklore music - September 2026

Beaches And Nature With Santa Teresa - September 2026

9 Days - The Best of Peru - September 2026

Mountains and Glaciers: El Calafate and Torres del Paine - September 2026

Rio de Janeiro to Santiago Travel Pass - September 2026

Full Costa Rica Explorer 14D/13N - September 2026

Tortuguero National Park Adventure 2D/1N - September 2026

From The Atlantic To The Pacific - September 2026

Ecuador - Andes to Amazon - September 2026

Page 25 of 1,216 Trips in South America during September 2026 with 3,429 Reviews

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All South America Tours in September 2026

Page 25 of 1,216 Trips in South America during September 2026 with 3,429 Reviews

Page 25 of 1,216 Trips in South America during September 2026 with 3,429 Reviews