10 Best South America Multiday Tours in September 2026

Ecuador - Andes to Amazon - September 2026

4.6

(11 reviews )

No booking fees

Best price guaranteed

This was a great trip with a good range of experiences, scenery, nature, culture, communities and food. Our guide was very knowledgeable and great at spotting and identifying birds. She judged exactly the right pace for walks and exploring, enabling everyone to participate fully. Ecuador is a wonderful country to visit and I thoroughly enjoyed the trip.

Active and outdoorExplorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

16-99 yrs

Operated in

english

Destinations

Quito, Guayaquil, Riobamba, Cuen

Quito, Guayaquil, Riobamba, Cuenca, Otavalo, Peguche, Cotopaxi National Park, Tena, Misahualli, Misicocha, Banos

Duration14 days

From

USD 2,760

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3 Day Wine & Dine Tour: Colchagua Valley - September 2026

Trip customizable

Best price guaranteed

Indulge yourself! This Colchagua three-day wine and dine tour is the perfect excuse to treat yourself to a weekend of wine and fine cuisine or the ideal romantic getaway with your partner. Spend three days in the beautiful valley of Colchagua. Fill your time with wine tastings, strolls through the vineyards, sampling the fine dining, and even a horseback ride if you choose. Personalize your trip by choosing either to spend the night in a boutique hotel in the Santa Cruz area or enjoying nature in a cosy countryside lodge. The Colchagua Valley is located approximately 180 km south of Santiago and is one of Chile's best-known wine areas! The area has won various awards for their full-bodied cabernet sauvignons, malbecs, merlots, syrahs and carménères. Despite a calm rural oasis atmosphere, the area has a rich culture and history. Come and experience this wonderful region!

Wine tasting toursFood tours

Tour Type

Private Tour

Accommodation

Lodge, Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Santiago, Colchagua Valley

Duration3 days

From

USD 965

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Best Of Peru, Private Tour - September 2026

15% OFF TODAY

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Best Of Peru, Private Tour - September 2026

Trip customizable

Best price guaranteed

Enjoy the best of Peru with this memorable seven-day tour from Lima to Cusco. Visit beautiful colonial cities, see the legacy of ancient civilizations, and admire some of the most spectacular landscapes on the planet. Meet the descendants of the Incas, the indigenous camelids of the Andes, and go on a pilgrimage to the mountain peaks to visit the magnificent citadel and mountain of Machu Picchu. Join this fantastic tour and catch a glimpse of Peru´s natural beauty, history, and culture.

Art and architectureHoneymoon

Tour Type

Private Tour

Accommodation

Hotel

Age Range

6-99 yrs

Operated in

english, spanish, french, portuguese

Destinations

Lima, Cusco, Sacred Valley

15% OFF TODAY

Duration7 days

From

USD 1,278

USD 1,087

Saving

USD 192

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Colombia Circuit (from Bogota) Travel Pass - September 2026

No booking fees

Best price guaranteed

Discover Colombia’s hidden gems with an unforgettable travel adventure starting in vibrant Bogota. Immerse yourself in local culture, explore stunning landscapes, and visit iconic landmarks such as the Salt Cathedral and Coffee Triangle. Experience the rich biodiversity of Tayrona National Park and the pristine beaches of the Caribbean coast. This all-encompassing journey offers exclusive experiences like coffee farm tours, cultural encounters, and breathtaking natural scenery, perfect for travelers seeking a comprehensive and authentic Colombia experience.

BeachCoffee and tea tours

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Bogota, Medellin, Manizales, Hac

Bogota, Medellin, Manizales, Hacienda Venecia Coffe Farm, Santa Marta, Cartagena

Duration14 days

From

USD 1,452

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Ushuaia & El Calafate Tour - September 2026

No booking fees

Best price guaranteed

Join us on this six-day, group tour that is the perfect combination of two amazing destinations in Argentina: Ushuaia, the southernmost city in the world, and El Calafate, a town near the Southern Patagonian Ice Field. We will pick you up on arrival in Ushuaia. Visit Tierra del Fuego National Park and see Bahia Lapataia as well as Lake Roca among other highlights before returning to the city to enjoy a Beagle Channel navigation by boat. See Bird´s Island, Sea Lion´s Island and Les Eclareirs Lighthouse. Head for El Calafate, home to the incredible Perito Moreno Glacier, Argentino Lake and Los Glaciares National Park. See Perito Moreno and explore Los Glaciares before its time to head home. Please note that domestic flights and national park entrance fees are not included in the tour price. For more details, please go through the itinerary below.

National parks

Tour Type

Group Tour

Accommodation

Hotel

Age Range

11-99 yrs

Operated in

English

Destinations

El Calafate, Ushuaia, Patagonia

El Calafate, Ushuaia, Patagonia, Perito Moreno Glacier

Duration6 days

From

USD 939

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Machu Picchu Calling - September 2026

Trip customizable

Best price guaranteed

Discover the lost land of the Incas and visit Machu Picchu on this 15 day tour of Peru. Starting in Lima we head south to the Ballestas Islands in the Paracas National Reserve. We get to see a huge array of birds and marine mammals on a boat ride through the islands. The next day we head through the Ica Desert on our way to Peru's wine regoin where we visit a winery before travelling to the Oasis of Huacachina where we have a chance to get our hearts pumping on an exhilarating dune buggy ride before settling down for a relaxing evening of camping under the stars. The next morning we are off to see the mysterious Nazca lines before heading to Arequipa for the night. We spend the next 4 days exploring Colca Canyon, we can select from additional activities like white water rafting, cycling, horse riding and trekking. We then travel to Cuzco where we visit some nearby sites before heading back to our hotel to prepare for our next adventure. We head out early the next morning from Cuzco to the Urubamba Valley from where we begin our 4 day trek along the Inca Trail to the unforgettable Machu Picchu. At the end of our trek we head back to Cuzco by train. The next day is free to explore Cuzco at your leisure, the next day you will be transferred to the airport for your departing flight.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Camping, Guest House

Age Range

16-85 yrs

Operated in

english

Destinations

Machu Picchu, Lima, Inca Trail

Machu Picchu, Lima, Inca Trail, Cusco, Ballestas Islands and Paracas National Reserve, Huacachina, Arequipa

Duration15 days

From

USD 4,365

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Simply Peru - September 2026

4.4

(8 reviews )

No booking fees

Best price guaranteed

Wonderful trip and Pavel was and brilliant leader.

Active and outdoorExplorer

Tour Type

Small Group Tour

Accommodation

Hotel, Guest House

Age Range

16-99 yrs

Operated in

english

Destinations

Cusco, Lima, Machu Picchu, Sacre

Cusco, Lima, Machu Picchu, Sacred Valley, Nazca, Arequipa, Chivay, Puno, Taquile Island

Duration14 days

From

USD 2,080

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Bolivian Amazon Pampas Adventure 4D/3N (from Rurrenabaque) - September 2026

No booking fees

Best price guaranteed

Embark on an unforgettable Bolivian Amazon adventure, exploring the pristine pampas from Rurrenabaque. Witness an incredible array of wildlife—pink river dolphins, caimans, and capybaras—in their natural habitat. Enjoy scenic boat rides, thrilling jungle treks, and authentic cultural encounters. This immersive experience promises birdwatching delights and unique opportunities to swim with dolphins. Ideal for nature enthusiasts and adventure seekers, this tour offers an extraordinary glimpse into the rich biodiversity of the Amazon rainforest.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Lodge, Hostel, Eco Lodge, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Rurrenabaque, Pampas

Duration4 days

From

USD 415

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The Ultimate Trek to Machu Picchu: Salkantay Trek 5 Days - September 2026

Trip customizable

Best price guaranteed

Salkantay Trek is a popular alternative to the very-crowded classic Inca Trail. It offers more distance, more mountains, more scenery, and a wider variety of landscapes, but still concludes with a visit to the iconic city of Machu Picchu. As the route does not have as many regulations as the Inca Trail, this also means that it can provide a “back door” trek to Machu Picchu when Inca Trail permits are sold out. This new itinerary, Salkantay Trek to Machu Picchu via Llaqtapata, includes the highlights of the other Salkantay trek, but avoids many of the areas that are becoming crowded with other trekkers. This trip is fully-inclusive, including a guide, accommodation, meals and transportation. Duration: 5 days/4 nights Distance trekked: about 50km Elevation: 1900-4600m Difficulty: Moderate Crowds: Moderate

Trekking and HikingMountains

Tour Type

Small Group Tour

Accommodation

Tent, Hotel, Camping

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Salkantay, Cusco, La Playa, Aguas Calientes

Duration5 days

From

USD 765

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14% OFF TODAY

Full Day Rio: Christ the Redeemer, Sugarloaf, City Tour and Buffet Lunch - September 2026

Trip customizable

Best price guaranteed

The tour begins with a visit to Corcovado Hill, where the famous statue of Christ the Redeemer is located, an image that conveys the faith and sympathy of the Carioca people. We'll have the opportunity to make the historic ascent, which will make this experience even more special! Then, we will continue to the top of Sugar Loaf Mountain, riding on the cable car that will give us a privileged view, enjoying the panoramic beauty of this place. We will also visit the Maracana Stadium, the Samba Museum, and the Historic center

Sailing, yachting and motor boating

Tour Type

Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Rio de Janeiro

14% OFF TODAY

Duration1 day

From

USD 140

USD 120

Saving

USD 20

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14% OFF TODAY

Volcanoes and Galapagos - September 2026

4.9

(28 reviews )

No booking fees

Best price guaranteed

A very varied trip with a full and exciting itinerary. So much to see and such interesting places to visit. All of our guides had extensive knowledge and Myriam in particular went beyond expectation to provide us with a deep insight into the social and economic history of this exciting country. A dream made real!

Active and outdoorWildlife

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

16-99 yrs

Operated in

english

Destinations

Quito, Guayaquil, Sierra Negra

Quito, Guayaquil, Sierra Negra, Isla Santa Cruz, Santa Fe Island, Tortuga Bay, Otavalo, Laguna Cuicocha, Mindo, Cotopaxi National Park, Galapagos Islands, Puerto Villamil

14% OFF TODAY

Duration15 days

From

USD 4,470

USD 3,830

Saving

USD 640

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Cusco / Machu Picchu Tour By Train - September 2026

(1 review )

Trip customizable

Best price guaranteed

If you like to discover new cultures, customs and feel the peace of nature, this unique tour of Cusco and Machu Picchu is all you need. We hope you will join us for an experience that will change your life. Right through the day or night, Cusco is a city that is full of charms and exciting tourist attractions. The mornings are ideal for strolling Inca streets, visiting colonial churches, visiting the legendary San Blas Artisan Quarter (craftsmen) or visiting Inca villages and archaeological remains. In the evenings, the city dresses up with lights, discos, pubs and restaurants, and its main tourist attractions come alive for visitors. The nightlife in Cusco is fun, exciting and unique, and it's certainly enough to satisfy the most demanding national and foreign visitors. The city of Cusco and Machu Picchu are without a doubt experiences you will cherish all your life.

ExplorerSightseeing Tours

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, japanese, portuguese, spanish

Destinations

Cusco, Aguas Calientes, Machu Pi

Cusco, Aguas Calientes, Machu Picchu, Lima

Duration6 days

From

USD 810

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Super Sales

Galapagos & Peru Adventure - September 2026

No booking fees

Best price guaranteed

Visit South America and travel to the Galapagos Islands, Peru, Ecuador, and Bolivia. Amazing wildlife, both on land and underwater, is the drawcard of the remote Galapagos Islands. Discover unique creatures, as well as the island's outstanding natural beauty, by foot, boat and bike. Back on the mainland, enjoy the delights of Peru – from the tough but rewarding Inca Trail to the joy of interacting with friendly locals and experiencing cities full of colour, energy and passion.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Camping, Lodge, Eco Lodge, Home-stay

Age Range

15-99 yrs

Operated in

english

Destinations

Quito, La Paz, Lima, Puerto Mald

Quito, La Paz, Lima, Puerto Maldonado, Amazon Lodge Tambopata, Cusco, Ollantaytambo, Inca Trail, San Cristobal Island, Puno, Isla Isabela, Isla Santa Cruz

Duration24 days

From

USD 8,580

USD 8,323

Saving

USD 257

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Tortuguero National Park Adventure 4D/3N - September 2026

No booking fees

Best price guaranteed

Embark on an unforgettable journey to Tortuguero National Park with Bamba and explore Costa Rica's vibrant wildlife and lush landscapes. Encounter exotic animals on guided nature walks, glide through serene waterways on canoe tours, and witness turtle nesting on pristine beaches. This eco-adventure offers a unique blend of relaxation and excitement, perfect for nature enthusiasts and adventure seekers alike. Experience the magic of Tortuguero with Bamba and create memories that will last a lifetime.

National parksWildlife

Tour Type

Small Group Tour

Accommodation

Lodge, Eco Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

San Jose, Tortuguero National Pa

San Jose, Tortuguero National Park, Tortuguero

Duration4 days

From

USD 836

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All South America Tours in September 2026

Page 26 of 1,217 Trips in South America during September 2026 with 3,429 Reviews

Ecuador - Andes to Amazon - September 2026

3 Day Wine & Dine Tour: Colchagua Valley - September 2026

Best Of Peru, Private Tour - September 2026

Colombia Circuit (from Bogota) Travel Pass - September 2026

Ushuaia & El Calafate Tour - September 2026

Machu Picchu Calling - September 2026

Simply Peru - September 2026

Bolivian Amazon Pampas Adventure 4D/3N (from Rurrenabaque) - September 2026

The Ultimate Trek to Machu Picchu: Salkantay Trek 5 Days - September 2026

Full Day Rio: Christ the Redeemer, Sugarloaf, City Tour and Buffet Lunch - September 2026

Volcanoes and Galapagos - September 2026

Cusco / Machu Picchu Tour By Train - September 2026

Galapagos & Peru Adventure - September 2026

Tortuguero National Park Adventure 4D/3N - September 2026

Page 26 of 1,217 Trips in South America during September 2026 with 3,429 Reviews

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All South America Tours in September 2026

Page 26 of 1,217 Trips in South America during September 2026 with 3,429 Reviews

Page 26 of 1,217 Trips in South America during September 2026 with 3,429 Reviews