10 Best South America Multiday Tours in September 2026

Uyuni Salt Flats & Desert Adventure 3D/2N (Uyuni to Uyuni) - September 2026

3.5

(2 reviews )

No booking fees

Best price guaranteed

Discover the breathtaking Uyuni Salt Flats with Bamba’s unforgettable adventure. This Bolivia tour offers an extraordinary journey through the world's largest salt flats, mesmerizing deserts, and colorful lagoons. Witness stunning sunsets, surreal landscapes, and local wildlife in their natural habitat. Capture perfect photos with creative perspective shots and marvel at the famous train cemetery. Experience local culture in traditional villages and stay in a unique salt hotel. This is the must-do Uyuni tour for adventure seekers and nature enthusiasts!

Desert safaris

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Uyuni, Agencha, Polques

Duration3 days

From

USD 345

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Journeys: Explore Colombia - September 2026

(12 reviews )

No booking fees

Best price guaranteed

Comprehensive, felt like I saw a wide spectrum of what Colombia has to offer, and a few surprises that I never would’ve sought out to experience myself!

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

12-100 yrs

Operated in

english

Destinations

Bogota, Cartagena, Armenia, Medellin

Duration9 days

From

USD 3,199

USD 3,103

Saving

USD 96

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Amazon, Incas & Titicaca - 13 days - September 2026

No booking fees

Best price guaranteed

Explore the Amazon, Inca ruins, Lake Titicaca and more on this 13 day tour of Peru, starting and ending in Lima. In the cultural capital of Lima, visit plazas, monasteries and underground crypts. Delve into the flora and fauna of the Amazon Jungle during a two night stay at a charming lodge before exploring captivating Cusco and the Sacred Valley. Marvel at magnificent Machu Picchu and take a boat trip on Lake Titicaca, to see the remarkable floating islands of Uros.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Bungalow

Age Range

18-80 yrs

Operated in

english

Destinations

Lima, La Paz, Puno, Lake Titicac

Lima, La Paz, Puno, Lake Titicaca, Puerto Maldonado, Cusco, Sacred Valley

Duration13 days

From

USD 3,615

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Mystical Tours of Peru and Bolivia - September 2026

Trip customizable

Best price guaranteed

Transport yourself to otherworldly landscapes and immerse yourself in the cultures of the Andes as you make your way across two countries—Peru and Bolivia. Take to the lunar-esque rock formations of the Moon Valley in Bolivia, or roam around the salt flat of Salar of Uyuni and its horizon-spanning natural mirror during rainy seasons for unforgettable scenery. Also, hop around the stunning floating islands of Uros and Isla del Sol, where you can explore the Incan landmarks like the Inca Garden, Pilcokaina Palace, the Stairway and the Sacred Fountain. Explore the red tile-lined houses of the village of Copacabana and get a bird’s eye view of the city of La Paz on board one of the longest cable urban air transport in the world.

Cultural, religious and historic sites

Tour Type

Group Tour

Accommodation

Guest House, Hotel

Age Range

12-75 yrs

Operated in

english, spanish

Destinations

La Paz, Puno, Uyuni, Uros Floating Islands

Duration5 days

From

USD 999

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Best Seller

Costa Rica Explorer - September 2026

(1 review )

Trip customizable

Best price guaranteed

A fantastic trip to a wonderful country. Hotels were all excellent. Everything worked very smoothly,with everything on time. Everyone extremely friendly. Just wish we could have stayed longer

VolcanoesNational parks

Tour Type

Private Tour

Accommodation

Hotel, Luxury Hotel

Age Range

1-90 yrs

Operated in

english, spanish

Destinations

San Jose, Manuel Antonio Nationa

San Jose, Manuel Antonio National Park, La Fortuna, Arenal Volcano, La Paz Waterfall, Arenal, Playa Potrero

Duration10 days

From

USD 2,950

Instant book available

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Walk Peru's Inca Trail and Palccoyo Rainbow Mountain - September 2026

4.8

(13 reviews )

No booking fees

Best price guaranteed

This was a wonderful trip. Lake Titicaca was stunning. Palccoyo Mountain was beautiful & a great introduction to high altitude walking. But the highlight was walking the Inca Trail & reaching Macchu Picchu. It was worth the 4 days of trekking to get that first glimpse through the sun gate. It was simply stunning. Our guide, Will, was exceptional. He took such great care of everyone in the group & shared the highlights of his wonderful country with us. All of the accommodation was great & the camping whilst on the trail was comfortable. The team of porters & cooks were simply brilliant (so much food!) I hope all of the trek team get a fair wage as the work they do is back-breaking. A couple of tips: go a night or 2 earlier if you want to see a bit of Lima. I flew in a day before the group flight & enjoyed seeing the best of the city (2 days was enough though). I’d also recommend getting the train between Puno & Cusco. It was a stunning journey & such a great way to see this beautiful country. If getting to Macchu Picchu is on your bucket list, do it, you won’t regret it.

Active and outdoor

Tour Type

Small Group Tour

Accommodation

Hotel, Tent, Camping

Age Range

16-99 yrs

Operated in

english

Destinations

Cusco, Lima, Intipunku, Ollantay

Cusco, Lima, Intipunku, Ollantaytambo, Machu Picchu, Puno, Uros Floating Islands, Llaqtapata

Duration14 days

From

USD 3,550

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Explore Peru, Argentina & Brazil - September 2026

No booking fees

Best price guaranteed

South America has many sides, from the energy of the cities and the beauty of the landscape to the spirit of the people. On this 18-day discovery, you’ll wind through the Inca heartlands and jungles of Peru, the enigmatic cities and natural wonders of Argentina and the dynamism of Brazil's vibrant Rio. See animals, meet locals, traverse trails and marvel at all the contrasts of this very special corner of the world. If you’re looking for a trip that hits not one, but two Wonders of the World off your bucket list – you’ve come to the right place. Take a guided tour of Machu Picchu, nestled high in the Andes Mountains, then visit Christ the Redeemer, overlooking breathtaking Rio. Wild ride, anyone?

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Home-stay

Age Range

15-99 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Buenos Air

Rio de Janeiro, Lima, Buenos Aires, Ituzaingo, Foz Do Iguacu, Iguazu Falls, Cusco, Aguas Calientes, Puno

Duration18 days

From

USD 7,205

USD 6,989

Saving

USD 216

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15% OFF TODAY

Super Sales

Essential South - September 2026

4.8

(4 reviews )

Trip customizable

Best price guaranteed

The Limatours service was magnificent. Very punctual at the airports as well as at the hotels. The guides are very kind

Art and architecture

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

6-99 yrs

Operated in

english, spanish

Destinations

Lima, Cusco, Sacred Valley, Agua

Lima, Cusco, Sacred Valley, Aguas Calientes, Puno

15% OFF TODAY

Duration9 days

From

USD 1,370

USD 1,164

Saving

USD 205

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27% OFF TODAY

Super Sales

Inca Discovery Plus - September 2026

(8 reviews )

No booking fees

Best price guaranteed

Wonderful experience that far exceeded expectations. Would recommend to anyone looking for an adventure.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Camping

Age Range

12-100 yrs

Operated in

english

Destinations

Lima, Cusco, Ollantaytambo, Llac

Lima, Cusco, Ollantaytambo, Llactapata, Dead Woman's Pass, Wiñay Wayna

27% OFF TODAY

Duration9 days

From

USD 1,749

USD 1,272

Saving

USD 477

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Cartagena To Manaus Inc. Guianas - September 2026

No booking fees

Best price guaranteed

Embark on the journey of a lifetime with an exploratory expedition which takes you throughout South America. Witness some of the most striking landscapes that this part of the world has to offer as you travel through dense rainforests, dry deserts and high altiplano. Experience pristine coastlines and vibrant cities as you get a real feel of the sights, sounds and flavours of the true South America. Please note that the accommodation on this trip is predominantly camping, though there may be opportunities to upgrade this locally where rooms are available. Please see the trip inclusions for an approximate percentage of camping and room nights

Overland Journeys

Tour Type

Group Tour

Accommodation

Camping, Resort, Lodge

Age Range

12-85 yrs

Operated in

english

Destinations

Cartagena, Manaus, Iguazu Falls

Cartagena, Manaus, Iguazu Falls, Taquaruçu, Belém, St. Laurent Du Maroni, Paramaribo, Georgetown, Boa Vista, Esteros Del Ibera, Pantanal, Rio de Janeiro, Ouro Preto, Caravelas, Salvador, Palmas, Buenos Aires

Duration201 days

From

USD 14,769

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Peru, Bolivia & Argentina Adventure - September 2026

18% OFF TODAY

Super Sales

Peru, Bolivia & Argentina Adventure - September 2026

No booking fees

Best price guaranteed

Follow the path of the Andes in South America on a 35-day adventure that hits both modern cities and ancient worlds. Spot birdlife circling canyons and search for signs of life in vast salt flats and lunar deserts scapes. Get acquainted with the local cultures at La Paz’s markets and the homes on the floating islands of Lake Titicaca. Learn the mysteries of the Nazca lines, wander the streets of Cusco and trek to the mighty Machu Picchu. With stops at Lima, Cusco and vibrant Buenos Aires and a local to lead the way, your South American adventure is jam-packed with fascinating experiences and plenty of space for independent travel.

City sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel, Camping, Home-stay

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Lima, Cusco, Inca

Buenos Aires, Lima, Cusco, Inca Trail, Puno, La Paz, Sucre, Potosi, Uyuni, Salar De Uyuni, Tupiza, Paracas, Tilcara, Nazca, Arequipa, Chivay

18% OFF TODAY

Duration35 days

From

USD 4,995

USD 4,118

Saving

USD 877

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Inca Trail & Amazon Adventure - September 2026

13% OFF TODAY

Super Sales

Inca Trail & Amazon Adventure - September 2026

(1 review )

No booking fees

Best price guaranteed

Very well organised, very good guides, good food except in the Amazon basin where the food could have been better.

Trekking and HikingMountains

Tour Type

Small Group Tour

Accommodation

Hotel, Camping, Lodge, Eco Lodge

Age Range

15-99 yrs

Operated in

english

Destinations

Inca Trail, Lima, Amazon Peru, C

Inca Trail, Lima, Amazon Peru, Cusco, Ollantaytambo, Aguas Calientes, Puerto Maldonado

13% OFF TODAY

Duration12 days

From

USD 2,780

USD 2,427

Saving

USD 353

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Tortuguero National Park Adventure 3D/2N - September 2026

(1 review )

No booking fees

Best price guaranteed

Tortuguero National park is the place to be seen for everyone who visit Costarica

National parksEco tours

Tour Type

Small Group Tour

Accommodation

Lodge, Eco Lodge, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Tortuguero National Park, San Jose

Duration3 days

From

USD 609

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Super Sales

Highlights of Peru - September 2026

4.8

(63 reviews )

No booking fees

Best price guaranteed

My husband and I had a wonderful trip, but our friends, who aren't as physically fit, had a hard time in the high altitudes - something to consider if you are older and not in good shape. The country is beautiful, the people were very friendly, and our main and local guides were wonderful.

Cultural, religious and historic sites

Tour Type

Group Tour

Accommodation

Hotel, Lodge

Age Range

5-99 yrs

Operated in

english

Destinations

Lima, Sacred Valley, Machu Picch

Lima, Sacred Valley, Machu Picchu, Cusco

Duration8 days

From

USD 7,475

USD 7,251

Saving

USD 224

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Accommodations

BudgetSimple stays with essential amenities. Typically guesthouses, hostels or hotels rated below 3 stars — clean, no-frills, and great for value-conscious travelers.
Mid-rangeComfortable and reliable 3-star stays. Expect private rooms, en-suite bathrooms, and solid amenities — a great balance between comfort and cost.
PremiumUpscale 4-5 star hotels and lodges. Enjoy high-end service, refined comfort, and premium locations — ideal for travelers seeking extra indulgence.

All South America Tours in September 2026

Page 13 of 1,212 Trips in South America during September 2026 with 3,430 Reviews

Uyuni Salt Flats & Desert Adventure 3D/2N (Uyuni to Uyuni) - September 2026

Journeys: Explore Colombia - September 2026

Amazon, Incas & Titicaca - 13 days - September 2026

Mystical Tours of Peru and Bolivia - September 2026

Costa Rica Explorer - September 2026

Walk Peru's Inca Trail and Palccoyo Rainbow Mountain - September 2026

Explore Peru, Argentina & Brazil - September 2026

Essential South - September 2026

Inca Discovery Plus - September 2026

Cartagena To Manaus Inc. Guianas - September 2026

Peru, Bolivia & Argentina Adventure - September 2026

Inca Trail & Amazon Adventure - September 2026

Tortuguero National Park Adventure 3D/2N - September 2026

Highlights of Peru - September 2026

Page 13 of 1,212 Trips in South America during September 2026 with 3,430 Reviews

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All South America Tours in September 2026

Page 13 of 1,212 Trips in South America during September 2026 with 3,430 Reviews

Page 13 of 1,212 Trips in South America during September 2026 with 3,430 Reviews