10 Best South America Multiday Tours in September 2026

Lima to Rio de Janeiro (via Uruguay) Travel Pass - September 2026

No booking fees

Best price guaranteed

Embark on the ultimate South American adventure with an incredible travel pass, journeying from Peru's vibrant capital to Brazil's lively Rio de Janeiro. Experience breathtaking landscapes, exotic wildlife, and rich cultural heritage. Highlights include exploring majestic Machu Picchu, tangoing in Buenos Aires, savoring Uruguayan cuisine, and basking on Rio's iconic beaches. This seamless travel pass provides an unforgettable, hassle-free way to discover the heart and soul of South America.

Trekking and HikingLagoons

Tour Type

Group Tour

Accommodation

Hotel, Hostel, Hut, Home-stay, Bungalow, Lodge, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Arequipa

Rio de Janeiro, Lima, Arequipa, Cuzco, Cusco, Luquina, Puno, Copacabana, La Paz, Paracas, Sucre, Potosi, Uyuni, Agencha, Polques, San Pedro De Atacama, Salta, Puerto Iguazu, Buenos Aires, Colonia Del Sacramento, Huacachina, Montevideo, Punta Del Este, Florianopolis, Sao Paulo, Paraty, Ilha Grande, Nazca, Colca Canyon

Duration53 days

From

USD 4,757

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Super Sales

South American Explorer - September 2026

(4 reviews )

No booking fees

Best price guaranteed

The trip was really good with lots of standout places and experiences. Our trip manager was brilliant. He was friendly and knowledgeable and made everything easy. Some of the accommodation wasn’t the best (poor showers, uncomfortable beds, no safety lock box, no elevator) but for the most part acceptable.

Trekking and Hiking

Tour Type

Group Tour

Accommodation

Hotel, Lodge

Age Range

18-35 yrs

Operated in

english

Destinations

Cusco, Rio de Janeiro, Buenos Ai

Cusco, Rio de Janeiro, Buenos Aires, Iguassu Falls, Sacred Valley, Aguas Calientes, Puerto Maldonado, Lima

Duration18 days

From

USD 5,085

USD 4,932

Saving

USD 153

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Tour Costa Rica Fly & Drive - September 2026

Trip customizable

Best price guaranteed

With its compact size, exotic environment, unspoiled beaches, romantic culture, and wild natural landscapes, Costa Rica is the perfect destination to explore by car on a self-drive trip. This is the perfect opportunity to explore on your own with just the right amount of planned activities and free time. From San José to Manuel Antonio, drive and enjoy the most picturesque areas of the country. Visit the famous canals of Tortuguero and the beautiful beaches of the South Caribbean. Drive to the majestic Arenal Volcano, towering above the picturesque village of La Fortuna. Visit the world-famous Monteverde Cloud Forest and enjoy an included day pass of adventure activities to explore with. Finally, discover the beautiful beaches of Manuel Antonio and include a visit to the lush Manuel Antonio National Park, considered one of the most beautiful in the world thanks to the rich biodiversity of its jungle and sea coast.

Beach

Tour Type

Private Tour

Accommodation

Eco Lodge, Hotel, Lodge, Resort

Age Range

18-79 yrs

Operated in

English

Destinations

San Jose, Manuel Antonio Nationa

San Jose, Manuel Antonio National Park, Tortuguero National Park, Monteverde Cloud Forest Biological Preserve, Arenal Volcano, Cahuita National Park, Arenal Volcano National Park

Duration13 days

From

USD 2,610

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Lares Trek to Machu Picchu 4D/3N - September 2026

(12 reviews )

No booking fees

Best price guaranteed

We had an amazing time and felt well taken care of. All the gudies were so kind and helpful. I would highly recommend doing the Lares Trek with Bamba Experience.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Camping, Hotel, Tent

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Machu Picchu, Lares Town

Cusco, Machu Picchu, Lares Town, Patacancha, Aguas Calientes

Duration4 days

From

USD 847

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Amazon Rainforest Sustainable Experience - September 2026

(1 review )

Trip customizable

Best price guaranteed

Everything went perfect. From the time I was picked up from the hotel in Manaus, the boat ride crossing the Negro and Amazon rivers, the drive from the pier to the boat ride to the resort. I was in awe of the beauty and enormity of the forest. While boating through the flooded path amidst the trees, I fell in love with the Amazon forest. Definitely coming back again.

Rainforest and jungle visits

Tour Type

Group Tour

Accommodation

Hotel, Lodge, Eco Lodge

Age Range

1-99 yrs

Operated in

english, portuguese, spanish

Destinations

Amazon Brazil, Manaus, Mamori, Tracajá

Duration6 days

From

USD 1,700

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Pantanal Wildlife Experience - September 2026

Trip customizable

Best price guaranteed

There is more to Brazil than beaches and the Amazon. You don't believe it? Then join us on this 5-day, guided trip and get the chance to explore the Pantanal, which is considered a World Heritage Site by UNESCO. Well, if you take the chance to get to know this breathtaking place, you’ll understand why. Besides being the largest wetland of the world, it’s home of a diverse flora and fauna. This site offers numerous attractions and unique experiences of contact with nature, thanks to the influence of three important biomes: Amazon, Cerrado and Atlantic Forest. Located in the Brazilian states of Mato Grosso and Mato Grosso do Sul, portions of this natural wonder extend as far as Bolivia and Paraguay. Spend five days exploring this unique place with us! *With COVID-19 safety protocols*

WildlifeLocal boat rides

Tour Type

Group Tour

Accommodation

Lodge, Eco Lodge

Age Range

1-90 yrs

Operated in

english, portuguese, spanish

Destinations

Pantanal, Cuiaba, Pousada Rio Cl

Pantanal, Cuiaba, Pousada Rio Claro, Campo Grande

Duration5 days

From

USD 1,750

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Mysteries of Peru's Sacred Valley - September 2026

(4 reviews )

Trip customizable

Best price guaranteed

The travel team designed a solo trip to Buenos Aires and Patagonia for me last year which was outstanding, so when I decided to go to Peru and Machu Picchu, I asked them to design a tour for me again. And again I was thrilled with their services! They tailored the trip to my specific interests and made adjustments as we went through the initial planning stagings until the trip was exactly what I wanted. When I travel alone in foreign countries, I don't want to have to worry about issues with transportation, safety, or unexpected changes to the itinerary. They arranged everything for me - transportation from each location with a driver and a bilingual guide to explain that portion of my trip. There were heavy rains in Machu Picchu before my arrival so some trails were closed and they made last minute arrangements for alternatives without problem. They provide you with multiple ways to contact them 24/7 while you're traveling, and I had to contact them once in the middle of the night to confirm a pickup time - they responded on What's App within 2 minutes and got the issue sorted immediately. I will use their company for any of my travels to South America - they are local experts, professional, and extremely easy to work with. Highly recommend!

Cultural, religious and historic sites

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Cusco, Machu Picchu, Lima, Pisac

Cusco, Machu Picchu, Lima, Pisac, Aguas Calientes

Duration8 days

From

USD 1,925

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Ausangate Trek 4D/3N - September 2026

No booking fees

Best price guaranteed

Embark on a mesmerising four-day adventure through the heart of the Andes, where high-altitude lagoons, serene mountain passes, and vibrant local communities await. From the azure Ausangate peaks to the psychedelic hues of Rainbow Mountain, each day promises unparalleled exploration and cultural immersion.

Trekking and HikingExplorer

Tour Type

Small Group Tour

Accommodation

Camping, Tent, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Ausangate, Jampa, Pacchanta

Duration4 days

From

USD 691

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Explore Tortuguero: The Amazon of Costa Rica - September 2026

Trip customizable

Best price guaranteed

Also called the Amazon of Costa Rica, Tortuguero National Park, located on the Caribbean coast, is home to a variety of wild animals and native plant species. Join us on this five-day tour of Tortuguero and soak up the rich biodiversity of this area. Exceptionally high rainfall and a unique environment where freshwater meets the sea means that Tortuguero has numerous canals, lagoons and wetlands, which you will discover during your guided boat safari and walking tour. Depending upon your arrival date, you might even get to see green sea turtles laying eggs on the beach. Please note that arrival and departure transfer is included in the tour price. However, you will have to purchase entrance tickets to Tortuguero National Park on your own. For more details, please go through the itinerary below.

Local boat ridesBeachWildlife

Tour Type

Private Tour

Accommodation

Hotel

Age Range

1-79 yrs

Operated in

english

Destinations

San Jose, Tortuguero National Park

Duration5 days

From

USD 675

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Rio de Janeiro to Buenos Aires (via Florianopolis & Iguazu) Travel Pass - September 2026

No booking fees

Best price guaranteed

Discover the ultimate South American adventure with a journey from vibrant Rio de Janeiro to cosmopolitan Buenos Aires, featuring Florianopolis and Iguazu Falls. Experience the iconic beaches of Rio, the nightlife of Florianopolis, and the breathtaking beauty of Iguazu. This travel pass offers thrilling activities like samba shows in Rio, exploring Iguazu's immense waterfalls, and savoring Argentine cuisine in Buenos Aires. Immerse yourself in diverse cultures and stunning landscapes, making unforgettable memories along the way!

City sightseeingWaterfalls

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Fl

Buenos Aires, Rio de Janeiro, Florianopolis, Foz Do Iguacu, Puerto Iguazu, Ilha Grande, Paraty, Sao Paulo

Duration17 days

From

USD 1,288

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Sacred Valley Day Trip - September 2026

(1 review )

No booking fees

Best price guaranteed

We have visit so many different sights. Our guide was doing an awesome job and you get a lot for this price.

Adventure

Tour Type

Small Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco

Duration10 hours

From

USD 23

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Sacred Valley Train to Machu Picchu 2D/1N - September 2026

(2 reviews )

No booking fees

Best price guaranteed

Well worth it! Our driver was Frank and guide was Jimmy. We were picked up at 07:45 from our hotel and dropped back to town centre around 18:30. We got to see so many beautiful landscapes within the Sacred Valley of the Inca. Jimmy was awesome, friendly and helpful. I definitely would recommend this day tour. We bought our entry ticket (tourism pass as they call it) once we got on the tour. Worked out better for us we only wanted to do the Sacred Valley tour. Thanks for a great day guys!

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Machu Picchu, Sacred Vall

Cusco, Machu Picchu, Sacred Valley, Aguas Calientes

Duration2 days

From

USD 492

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Tortuguero National Park Adventure - September 2026

(2 reviews )

Trip customizable

Best price guaranteed

Tortuguero was full of great nature, although the heat and lack of fans and air conditioning can be brutal at times. Puerto Viejo/Cocles was our favorite and it was great to see the Caribbean side of Costa Rica; all of the experiences there were fantastic as well. Overall, we enjoyed our honeymoon and hope to make it back to Costa Rica to visit the other side of the coast in the future!

National parksWildlife

Tour Type

Group Tour

Accommodation

Hotel, Lodge, Eco Lodge

Age Range

2-79 yrs

Operated in

english, spanish

Destinations

San Jose, Tortuguero National Park

Duration5 days

From

USD 765

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Iquitos Amazon Jungle Adventure 4D/3N - September 2026

No booking fees

Best price guaranteed

Embark on an enthralling Amazon rainforest adventure with breathtaking wildlife encounters and guided jungle treks. Explore Iquitos' vibrant river life, visit indigenous communities, and cruise along the Amazon River spotting exotic animals. Delight in night safaris, canopy walks, and piranha fishing, all while surrounded by lush, unspoiled nature. Perfect for nature enthusiasts and thrill-seekers alike, this immersive tour promises a unique and unforgettable experience in one of the world's most biodiverse regions. Secure your jungle escape today!

ExplorerAdventure

Tour Type

Small Group Tour

Accommodation

Lodge, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Amazon Peru, Iquitos, Lima

Duration4 days

From

USD 750

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All South America Tours in September 2026

Page 12 of 320 Trips in South America during September 2026 with 831 Reviews

Lima to Rio de Janeiro (via Uruguay) Travel Pass - September 2026

South American Explorer - September 2026

Tour Costa Rica Fly & Drive - September 2026

Lares Trek to Machu Picchu 4D/3N - September 2026

Amazon Rainforest Sustainable Experience - September 2026

Pantanal Wildlife Experience - September 2026

Mysteries of Peru's Sacred Valley - September 2026

Ausangate Trek 4D/3N - September 2026

Explore Tortuguero: The Amazon of Costa Rica - September 2026

Rio de Janeiro to Buenos Aires (via Florianopolis & Iguazu) Travel Pass - September 2026

Sacred Valley Day Trip - September 2026

Sacred Valley Train to Machu Picchu 2D/1N - September 2026

Tortuguero National Park Adventure - September 2026

Iquitos Amazon Jungle Adventure 4D/3N - September 2026

Page 12 of 320 Trips in South America during September 2026 with 831 Reviews

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Food, wine, events and nightlife

Adventure and sport

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Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

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All South America Tours in September 2026

Page 12 of 320 Trips in South America during September 2026 with 831 Reviews

Page 12 of 320 Trips in South America during September 2026 with 831 Reviews