10 Best South America Multiday Tours in September 2027

Accommodations

BudgetSimple stays with essential amenities. Typically guesthouses, hostels or hotels rated below 3 stars — clean, no-frills, and great for value-conscious travelers.
Mid-rangeComfortable and reliable 3-star stays. Expect private rooms, en-suite bathrooms, and solid amenities — a great balance between comfort and cost.
PremiumUpscale 4-5 star hotels and lodges. Enjoy high-end service, refined comfort, and premium locations — ideal for travelers seeking extra indulgence.

South America Discovery: Lima To Rio De Janiero - September 2027

13% OFF TODAY

Black Week Super Sales

South America Discovery: Lima to Rio de Janiero - September 2027

(3 reviews )

No booking fees

Best price guaranteed

We had the trip of a lifetime and I will be recommending it to all my friends and family. Thanks G for an awesome trip!

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Hotel, Resort

Age Range

12-100 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, La Paz, Su

Rio de Janeiro, Lima, La Paz, Sucre, Potosi, Uyuni, Salt Flats, San Pedro De Atacama, Cusco, Santiago, Valparaiso, Pucon, San Carlos de Bariloche, Buenos Aires, Foz Do Iguacu, Paraty, Ilha Grande, Ollantaytambo, Aguas Calientes, Puno

13% OFF TODAY

Duration38 days

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18% OFF TODAY

Black Week Super Sales

Solo-ish Ecuador - September 2027

No booking fees

Best price guaranteed

Dreaming of an adventure through Ecuador’s breathtaking landscapes and the heart of the Amazon but don’t want to go it alone? Good news: Ecuador’s irresistible charm is calling, and this Solo-ish adventure is your perfect ticket in. Stand right on the Equator at the Intiñan Museum, take in the towering beauty of Cotopaxi — one of the world’s highest active volcanoes — and soak in the magic of Baños with its cloud forests, waterfalls, and hot springs. Then, dive into the dense Amazon jungle, where warm hospitality and wild beauty await. Over seven unforgettable days, you’ll experience it all alongside fellow solo travellers who are just as ready for the adventure as you are.

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge

Age Range

18-100 yrs

Operated in

english

Destinations

Quito, Banos, Tena

18% OFF TODAY

Duration7 days

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Black Week Super Sales

Sao Paulo, Rio de Janeiro & Iguazu Falls - September 2027

Trip customizable

Best price guaranteed

Embark on an unforgettable 9-day journey through Brazil’s most iconic destinations: São Paulo, Rio de Janeiro, and Iguazu Falls. Start your adventure in São Paulo, Brazil's vibrant financial hub and cultural capital, where the bustling streets are alive with diverse culinary delights, world-class museums, and eclectic neighborhoods. Next, head to Rio de Janeiro, a dazzling coastal city renowned for its stunning beaches—Copacabana and Ipanema—the awe-inspiring 38-meter-high Christ the Redeemer statue atop Corcovado Hill, and the panoramic views from Sugar Loaf Mountain, accessible via thrilling cable car rides. Your journey culminates at the breathtaking Iguazu Falls, a natural wonder straddling the border between Brazil and Argentina. Marvel at the sheer power and beauty of 275 individual waterfalls, with the tallest, the 80-meter Devil’s Throat, offering an unforgettable spectacle. Iguazu Falls is truly one of the seven natural wonders of the world and a must-visit on any South American itinerary. This tour promises a perfect blend of urban excitement, natural beauty, and cultural immersion, showcasing the very best of Brazil’s diverse landscapes and vibrant cities.

Rainforest and jungle visits

Tour Type

Independent Tour

Age Range

1-79 yrs

Operated in

english, spanish

Destinations

Iguazu Falls, Sao Paulo, Rio de

Iguazu Falls, Sao Paulo, Rio de Janeiro, Iguazu Falls National Park, Foz De Iguazú, Foz Do Iguacu, Puerto Iguazu

Duration9 days

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Black Week Super Sales

Inca Journey: Machu Picchu by Train & The Amazon - September 2027

(2 reviews )

No booking fees

Best price guaranteed

Our trip to Peru was executed flawlessly thanks to the organization and effort of G Adventures and our incredible guide, Wenny. We got to see and experience so many different things and Wenny took such amazing care of our group. This was our second trip with G Adventures and we plan to do more... we have never been disappointed and always make the best memories!

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel, Hut, Lodge

Age Range

12-100 yrs

Operated in

english

Destinations

Cusco, Lima, Sacred Valley, Agua

Cusco, Lima, Sacred Valley, Aguas Calientes, Tambopata

Duration9 days

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Amazon To Andes With Machu Picchu By Train - September 2027

32% OFF TODAY

Black Week Super Sales

Amazon to Andes with Machu Picchu by Train - September 2027

(4 reviews )

No booking fees

Best price guaranteed

It has been a fantastic experience. I didn’t know what to expect from an organised tour. I usually organise my own trips, but I have been impressed. The level or organisation and attention experienced was second to none. I’d choose G adventures again without hesitation.

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Hotel

Age Range

12-100 yrs

Operated in

english

Destinations

Lima, Amazon Jungle, Cusco, Olla

Lima, Amazon Jungle, Cusco, Ollantaytambo, Aguas Calientes

32% OFF TODAY

Duration12 days

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18% OFF TODAY

Black Week Super Sales

Bolivia Encounter - September 2027

No booking fees

Best price guaranteed

Explore South America's salt flats, ancient deserts, geysers and valleys on this nine-day adventure from Bolivia to Chile. Ride the teleferico (cable car) over the world’s tallest capital city (La Paz), explore the Andrean Desert and travel across the Uyuni Salt Flats with a local leader by your side. Learn about ancient rock carvings at Yerbas Buenas, soak in the hot springs of Polques and see flamingo-filled lagoons and lunar valleys as you cross into the Atacama Desert – one of the driest places on Earth! Cross the border to Chile, watch the sun rise over Rainbow Canyon and indulge in Bolivian and Chilean cuisine every step of the way.

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

La Paz, Uyuni, Silolio Dykuma, San Pedro De Atacama

18% OFF TODAY

Duration9 days

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Express Peru With Machu Picchu By Train - September 2027

18% OFF TODAY

Black Week Super Sales

Express Peru with Machu Picchu by Train - September 2027

No booking fees

Best price guaranteed

Step into the past and embrace the rich cultures of Peru on this unforgettable six-day adventure, starting and ending in Cusco. Take in the breathtaking views of the Sacred Valley, dive into the history of Cusco, and ride the train to Aguas Calientes before witnessing the legendary Machu Picchu in all its glory. Wander through ancient ruins, browse vibrant local markets, and uncover the stories hidden within museums. With decades of experience, G Adventures brings you the best local guides, so you can fully immerse yourself in the magic and mystery of Peru — no distractions, just adventure.

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel, Hut

Age Range

12-100 yrs

Operated in

english

Destinations

Cusco, Sacred Valley, Aguas Calientes

18% OFF TODAY

Duration6 days

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Colombian Adventure: Hot Springs & Bogotá Streets - September 2027

18% OFF TODAY

Black Week Super Sales

Colombian Adventure: Hot Springs & Bogotá Streets - September 2027

No booking fees

Best price guaranteed

From friendly locals to vibrant neighbourhoods, misty mountains, and endless coffee-covered hills, this eight-day adventure from Medellín to Bogotá is packed with everything that makes Colombia unforgettable. Start your journey in an outdoor enthusiast’s paradise, then kick back in a small town bubbling with volcanic thermal pools. Wander through the lush green beauty of the Cocora Valley, where the landscape feels straight out of a dream. With grand colonial architecture, epic views from a towering granite rock, and a mix of hidden gems, you’ll experience the true heart of Colombia — far from the usual tourist trail.

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-39 yrs

Operated in

english

Destinations

Bogota, Medellin, Guatapé, Santa

Bogota, Medellin, Guatapé, Santa Rosa De Cabal, Salento

18% OFF TODAY

Duration8 days

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Black Week Super Sales

Cusco City Tour with Family-Style Lunch - September 2027

Trip customizable

Best price guaranteed

Your tour starts with a walking tour to visit the principal local market, San Pedro. Then, walk around Cusco’s city center, visiting the beautiful main square and the Cathedral of Cusco, which holds many archaeological artifacts and relics. Among them is a famous painting of the Last Supper by Marcos Zapata, showing Christ and the apostles eating a guinea pig. Continue your tour to the huge Inca ceremonial center of Sacsayhuaman, which overlooks the city of Cusco. Then visit another important Inca site known as Qenqo, which houses subterranean passages and a mummification site. After that, you will make a short visit to the archaeological Inca site of Tambomachay, a temple dedicated to the god of water. We will have a lovely home-style lunch, in the heart of the traditional neighborhood of San Blas, in a picturesque, rustic courtyard surrounded by cherry trees and tumbles. Perfect for an outdoor lunch next to the wood-fired oven accompanied by a melodious Andean harp. After lunch, we will return to the city center, where you will visit one of the most sacred Inca buildings, the Temple of Qoricancha. Within its walls religious ceremonies were constant, and offerings to the Gods and the Inca’s mummies were made each day. After the city tour you will be dropped off at your hotel.

ExplorerWalking tours

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Cusco

Duration1 hour

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Ecuador, Galapagos & Peru Explorer - September 2027

18% OFF TODAY

Black Week Super Sales

Ecuador, Galapagos & Peru Explorer - September 2027

No booking fees

Best price guaranteed

This well-rounded adventure focuses on South America’s heavy hitters – the Amazon, the Galapagos and the Andes. Take 25 days to explore these wildly different parts of the region. Snorkel the turtle-filled waters of Leon Dormido, then wander the ancient cobblestone streets of Cusco. Visit an organic farm where giant tortoises roam freely, and later conquer the 4215-m-high Dead Woman’s Pass on the Inca Trail. Hike to the top of one of the most active volcanoes in the Galapagos, then stand in awe of the man-made elegance of Machu Picchu. This is an immersive and active trip in two of South America’s bucket-list destinations.

Explorer

Tour Type

Small Group Tour

Accommodation

Camping, Eco Lodge, Home-stay, Hotel, Lodge

Age Range

15-99 yrs

Operated in

english

Destinations

Quito, San Cristobal Island, Isl

Quito, San Cristobal Island, Isla Isabela, Isla Santa Cruz, Lima, Cusco, Tena, Ollantaytambo, Inca Trail, Banos, Yunguilla

18% OFF TODAY

Duration25 days

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South America Tours in September 2027

Page 10 of 109 Trips in South America during September 2027 with 8,181 Reviews

Page 10 of 109 Trips in South America during September 2027 with 8,181 Reviews

South America Discovery: Lima to Rio de Janiero - September 2027

Solo-ish Ecuador - September 2027

Sao Paulo, Rio de Janeiro & Iguazu Falls - September 2027

Inca Journey: Machu Picchu by Train & The Amazon - September 2027

Amazon to Andes with Machu Picchu by Train - September 2027

Bolivia Encounter - September 2027

Express Peru with Machu Picchu by Train - September 2027

Colombian Adventure: Hot Springs & Bogotá Streets - September 2027

Cusco City Tour with Family-Style Lunch - September 2027

Ecuador, Galapagos & Peru Explorer - September 2027

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Food, wine, events and nightlife

Adventure and sport

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Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

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Special interests and hobbies

South America Tours in September 2027

Page 10 of 109 Trips in South America during September 2027 with 8,181 Reviews

Page 10 of 109 Trips in South America during September 2027 with 8,181 Reviews