10 Best South America Multiday Tours in September 2027

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Santiago to Buenos Aires: Volcanos, Valleys & the Lake District - September 2027

No booking fees

Best price guaranteed

Pack your bags and get ready to bounce through South America on this 12-day ride full of wild nature, epic nights, and laid-back lake vibes. Start in Santiago and hop an overnight bus to Pucón, where volcanoes, hot springs, and endless adventure await. Cruise through Chile’s dreamy Lake District with a chill stop in Puerto Varas, then cross into Argentina to explore the outdoorsy paradise of Bariloche. Hike, bike, or just soak it all in — your pace, your way. Wrap things up in buzzing Buenos Aires with tango, steak, and one last big night out. This is South America in full colour, and you’re living it large.

Explorer

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-39 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Pucon, P

Buenos Aires, Santiago, Pucon, Puerto Varas, San Carlos de Bariloche

Duration12 days

From

USD 1,599

USD 1,551

Saving

USD 48

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Colombian Adventure: Hot Springs & Bogotá Streets - September 2027

No booking fees

Best price guaranteed

From friendly locals to vibrant neighbourhoods, misty mountains, and endless coffee-covered hills, this eight-day adventure from Medellín to Bogotá is packed with everything that makes Colombia unforgettable. Start your journey in an outdoor enthusiast’s paradise, then kick back in a small town bubbling with volcanic thermal pools. Wander through the lush green beauty of the Cocora Valley, where the landscape feels straight out of a dream. With grand colonial architecture, epic views from a towering granite rock, and a mix of hidden gems, you’ll experience the true heart of Colombia — far from the usual tourist trail.

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-39 yrs

Operated in

english

Destinations

Bogota, Medellin, Guatapé, Santa

Bogota, Medellin, Guatapé, Santa Rosa De Cabal, Salento

Duration8 days

From

USD 1,199

USD 1,163

Saving

USD 36

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Complete Colombia: Coastal Caribbean & Inland Hidden Gems - September 2027

No booking fees

Best price guaranteed

We get it, choosing the right itinerary for a country as diverse as Colombia is tough. But we’ve got you covered with this 17-day whirlwind adventure that ticks all the boxes. From coastal Cartagena to vibrant Bogotá, explore the best of both worlds: iconic highlights and hidden gems. Trek the jungle trails of Tayrona National Park, dive into waterfall plunge pools in Minca, soak in the chill vibes of Palomino, and uncover the lesser-known hot springs of Santa Rosa de Cabal. With adventures at every turn and plenty of time to soak in the culture, you’ll come home with stories — and a deeper connection to Colombia — that’ll last a lifetime.

Explorer

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel, Villa

Age Range

18-39 yrs

Operated in

english

Destinations

Bogota, Cartagena, Medellin, Gua

Bogota, Cartagena, Medellin, Guatapé, Santa Rosa De Cabal, Salento, Minca, Palomino, Tayrona National Park, Santa Marta

Duration17 days

From

USD 2,749

USD 2,667

Saving

USD 82

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Super Sales

Colombian Explorer: Medellín Nights & Tayrona National Park - September 2027

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Best price guaranteed

Forget scrolling and start experiencing the real deal. This 11-day adventure through Colombia’s Caribbean coast is all about soaking up the sun, culture, and natural beauty of this vibrant country. Kick off in Cartagena’s charming walled city before venturing into the lush jungles of Minca and Palomino. Hike to hidden waterfalls, chill on the beaches of Santa Marta, and explore national parks packed with adventure. Wrap it all up with the electric vibes of Medellín. These spots may be all over your feed, but trust us, they’re even better in person — so what are you waiting for?

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel, Villa

Age Range

18-39 yrs

Operated in

english

Destinations

Cartagena, Medellin, Minca, Palo

Cartagena, Medellin, Minca, Palomino, Tayrona National Park, Santa Marta

Duration10 days

From

USD 1,599

USD 1,551

Saving

USD 48

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Monkeys, Jungles And Volcanoes - September 2027

15% OFF TODAY

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Monkeys, Jungles and Volcanoes - September 2027

4.8

(12 reviews )

No booking fees

Best price guaranteed

The itinerary for Monkeys, Jungles, & Volcanoes was wonderful. Travels went at a good pace for most of the group. Accommodations were quite good, even at the more primitive hotel. Hot water for showers and flushing toilets. Stops along the way were very interesting and local business owners very friendly & helpful. Our guide, *Personal details removed by Feefo*, was the best and coach driver, *Personal details removed by Feefo* was also quite professional and efficient at navigating narrow roads. The major destinations (Arenal, Tortuguero, and *Personal details removed by Feefo*) were all quite beautiful with plenty of fascinating wildlife and lovely landscapes.

Tour Type

Group Tour

Accommodation

Hotel, Lodge, Resort

Age Range

5-99 yrs

Operated in

english

Destinations

San Jose, Tortuguero National Pa

San Jose, Tortuguero National Park, Arenal, Manuel Antonio

15% OFF TODAY

Duration8 days

From

USD 2,535

USD 2,164

Saving

USD 371

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8% OFF TODAY

Super Sales

Real Bolivia to Brazil - September 2027

No booking fees

Best price guaranteed

Take an adventure in diverse South America on this 25-day trip from La Paz to Rio de Janeiro. See amazing natural wonders, walk the streets of busy cities and meet the charming locals with a leader by your side who knows all the best spots. Tour the city of Colonia del Sacramento, discover why Salta is nicknamed ‘La Linda’ (‘the beautiful’) and tick immersive Buenos Aires off your bucket list with your new group of friends. Witness the magic of the Iguazu Falls, journey through the untamed desert scenery of San Pedro de Atacama and see the otherworldly Salar de Uyuni salt flats. You’ll have plenty of free time to explore each location, and all the logistics are taken care of for you, so you can concentrate on making new connections and discovering new places.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-35 yrs

Operated in

english

Destinations

Rio de Janeiro, La Paz, Buenos A

Rio de Janeiro, La Paz, Buenos Aires, Montevideo, Estancia, Iguazu Falls, Paraty, Ilha Grande, Salar De Uyuni, Altiplano, San Pedro De Atacama, Salta

8% OFF TODAY

Duration25 days

From

USD 4,735

USD 4,363

Saving

USD 372

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Super Sales

Epic South America - September 2027

No booking fees

Best price guaranteed

Experience the full spectrum of South America on this epic 39-day adventure – the perfect way to forge lifelong connections. Follow in the footsteps of ancient people on the Inca Trail in Peru, drive past volcanoes, lakes, llamas and flamingos in the Atacama Desert and marvel at the might of Iguazu Falls. Spend nights on an estancia (farm) in Uruguay and at a homestay on Lake Titicaca, sample Argentinian barbecue in Buenos Aires and roam through the Amazon jungle. With like-minded travel companions and a local leader providing recommendations at every stop, this’ll be a South American expedition like no other.

Adventure

Tour Type

Small Group Tour

Accommodation

Camping, Home-stay, Hotel, Lodge

Age Range

18-35 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Puno, Lake

Rio de Janeiro, Lima, Puno, Lake Titicaca, La Paz, Salar De Uyuni, Altiplano, San Pedro De Atacama, Puerto Maldonado, Salta, Buenos Aires, Montevideo, Estancia, Cusco, Iguazu Falls, Iguazu Falls, Paraty, Ilha Grande, Ollantaytambo, Inca Trail

Duration39 days

From

USD 7,250

USD 7,033

Saving

USD 218

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Real Argentina To Brazil - September 2027

18% OFF TODAY

Super Sales

Real Argentina to Brazil - September 2027

No booking fees

Best price guaranteed

Embark on a South American escapade from Buenos Aires to Rio de Janeiro on this 14-day adventure. Soak up the might of Argentina before crossing to the charming city of Colonia del Sacramento, then explore the lively Mercado del Puerto in Montevideo. Spend two nights getting to know the locals on an estancia (farm) in Uruguay, either chipping in with the chores or relaxing in the sun, then marvel at the majesty of Iguazu Falls. Finishing off in the paradise of Ilha Grande and the buzz of Rio de Janeiro, you’ll experience the many sides of South America.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-35 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Pa

Buenos Aires, Rio de Janeiro, Paraty, Ilha Grande, Montevideo, Estancia, Iguazu Falls

18% OFF TODAY

Duration14 days

From

USD 2,895

USD 2,387

Saving

USD 508

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10% OFF TODAY

Super Sales

Peru Explorer - September 2027

4.5

(18 reviews )

No booking fees

Best price guaranteed

Everything was planned out well and the excursions were good choices. The hotels we very nice.

Adventure

Tour Type

Group Tour

Accommodation

Hotel

Age Range

5-99 yrs

Operated in

english

Destinations

Cusco, Lima, Sacred Valley

10% OFF TODAY

Duration7 days

From

USD 2,939

USD 2,638

Saving

USD 301

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All South America Tours in September 2027

Page 4 of 51 Trips in South America during September 2027 with 222 Reviews

Page 4 of 51 Trips in South America during September 2027 with 222 Reviews

Santiago to Buenos Aires: Volcanos, Valleys & the Lake District - September 2027

Colombian Adventure: Hot Springs & Bogotá Streets - September 2027

Complete Colombia: Coastal Caribbean & Inland Hidden Gems - September 2027

Colombian Explorer: Medellín Nights & Tayrona National Park - September 2027

Monkeys, Jungles and Volcanoes - September 2027

Real Bolivia to Brazil - September 2027

Epic South America - September 2027

Real Argentina to Brazil - September 2027

Peru Explorer - September 2027

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All South America Tours in September 2027

Page 4 of 51 Trips in South America during September 2027 with 222 Reviews

Page 4 of 51 Trips in South America during September 2027 with 222 Reviews