10 Best South America Multiday Tours in October 2025

Machu Picchu & Lake Titicaca - 11 days - October 2025

No booking fees

Best price guaranteed

Take in the highlights of Peru's capital before flying to captivating Cusco, the historic capital of the Inca Empire. Discover the wonders of the Sacred Valley and enjoy an incredibly scenic train journey to the spectacular 'lost city' of Machu Picchu. Meet the islanders of Lake Titicaca and end your adventure back in Lima on this 11 day tour of Peru.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Lima, Cusco, Sacred Valley, Mach

Lima, Cusco, Sacred Valley, Machu Picchu, Lake Titicaca

Duration11 days

From

USD 2,995

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Machu Picchu Express - 5 days - October 2025

No booking fees

Best price guaranteed

Explore the Sacred Valley of the Incas and the spectacular lost city of Machu Picchu on this 5 day tour, which starts and ends in Cusco. Take in the highlights of the captivating Cusco on a walking tour, discover the vast Inca fortress of Ollantaytambo and the Pisac ruins before travelling by train for a guided tour of the iconic Machu Picchu citadel, one of the New Seven Wonders of the World.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Cusco, Sacred Valley, Machu Picchu

Duration5 days

From

USD 1,345

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Incas, Titicaca & La Paz - 12 days - October 2025

No booking fees

Best price guaranteed

Travel from Lima to La Paz on this 12 day tour, taking in the highlights of Peru before crossing into Bolivia to visit the charming lakeside town of Copacabana and the world's highest capital city. Discover the delights of Lima, Cusco and La Paz on guided city tours and take a boat trip on Lake Titicaca to meet the islanders. Explore Pisac and Ollantaytambo Fortress in the beautiful Sacred Valley and marvel at Machu Picchu, the spectacular lost city of the Incas.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Lima, La Paz, Cusco, Sacred Vall

Lima, La Paz, Cusco, Sacred Valley, Puno

Duration12 days

From

USD 2,975

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Super Sales

Galapagos Escape - Solaris (Itinerary B) - October 2025

No booking fees

Best price guaranteed

With lumbering giant tortoises, playful sea lions and an aviary of swooping, squawking, soaring bird life, the Galapagos Islands is wildlife-watching heaven. For this five-day trip, it’s all aboard the Solaris, a first-class motor yacht, to cruise around the archipelago in the company of an expert naturalist. Along the way, we stop at a string of biologically diverse islands, including Genovesa, Santa Fe and San Cristóbal, with the chance to get out and explore on foot and by snorkelling. Expect moments worthy of a nature documentary and plenty of photo opportunities.

WildlifeBird watching

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

12-99 yrs

Operated in

english

Destinations

Quito, Guayaquil, Baltra Island

Quito, Guayaquil, Baltra Island, Mosquera Island, Genovesa Island, Santa Fe

Duration6 days

From

USD 4,835

USD 4,690

Saving

USD 145

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Peru, Canyon & Jungle - 17 days - October 2025

No booking fees

Best price guaranteed

Discover the treasures of Peru from the spectacular depths of Colca Canyon to the dizzying heights of Machu Picchu and the Incan citadel. Take in the floating islands of Lake Titicaca staying with the local Aymara people before delving into the exotic Amazon Rainforest for a jungle experience.

Sightseeing Tours

Tour Type

Private Tour

Accommodation

Home-stay, Lodge, Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Lima, Cusco, Puerto Maldonado, A

Lima, Cusco, Puerto Maldonado, Arequipa, Puno

Duration17 days

From

USD 5,465

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Peru & Iquitos Amazon Cruise - 11 days - October 2025

No booking fees

Best price guaranteed

Delve deep into the Amazon Rainforest in northern Peru on a luxury 4 day cruise, searching for three-toed sloths, toucans and endangered pink dolphins. Travel onwards to the majestic 'Lost City' of Machu Picchu, explore the Sacred Valley and meet the islanders of Lake Titicaca on this 11 day tour.

Cruise

Tour Type

Private Tour

Accommodation

Ship Cabin, Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Lima, Puno, Lake Titicaca, Nauta

Lima, Puno, Lake Titicaca, Nauta, Iquitos, Cusco, Sacred Valley

Duration11 days

From

USD 6,885

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Luxury Peru & Andean Explorer - 12 days - October 2025

No booking fees

Best price guaranteed

Discover Peru in style on this 12 day private tour which includes 2 night's aboard the luxurious Andean Explorer train. Travel along one of the highest rail routes in the world, cruise to the Uros Islands on Lake Titicaca and explore historic Cusco. Ride the Hiram Bingham train to Machu Picchu, explore Lima, the "City of Kings" and create delicious dishes in Arequipa.

Train toursCruise

Tour Type

Private Tour

Accommodation

Lodge, Sleeper Train, Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Lima, Arequipa, Sacred Valley, M

Lima, Arequipa, Sacred Valley, Machu Picchu, Aguas Calientes, Cusco, Lake Titicaca

Duration12 days

From

USD 10,085

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Into the Incan Empire - 8 days - October 2025

No booking fees

Best price guaranteed

This classic journey through the Inca heartland of Peru takes you from elegant Lima to Cusco and its archaeological riches. Explore megalithic fortresses and ancient terraces, traditional Andean villages and colourful markets before culminating in the spectacular ‘Lost City’ of Machu Picchu.

Cultural, religious and historic sites

Tour Type

Private Tour

Accommodation

Hotel, Lodge

Age Range

18-80 yrs

Operated in

english

Destinations

Lima, Urubamba, Machu Picchu, Cusco

Duration8 days

From

USD 3,005

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Best of Peru & Bolivia - 15 days - October 2025

No booking fees

Best price guaranteed

Discover the wonders of Peru and Bolivia on this 15 day private tour which starts in Lima and ends in lofty La Paz. Marvel at the legendary Machu Picchu - the Lost City of the Incas, meet the islanders on beautiful Lake Titicaca, explore the shimmering white plains of the Uyuni salt flats and more!

Explorer

Tour Type

Private Tour

Accommodation

Hotel, Lodge

Age Range

18-80 yrs

Operated in

english

Destinations

Lima, La Paz, Sucre, Uyuni, Sacr

Lima, La Paz, Sucre, Uyuni, Sacred Valley, Machu Picchu, Aguas Calientes, Cusco, Lake Titicaca

Duration15 days

From

USD 6,975

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Peru Encompassed - 20 days - October 2025

No booking fees

Best price guaranteed

Explore the incredibly diverse country of Peru and three of its contrasting landscapes – the Andean mountains, the desert and the Amazon rainforest. Get a taste of Bolivia in La Paz, see condors soar over the Colca Canyon and discover the Lost City of Machu Picchu.

Cultural, religious and historic sites

Tour Type

Group Tour

Accommodation

Hotel, Lodge

Age Range

18-80 yrs

Operated in

english

Destinations

Lima, La Paz, Cusco, Sacred Vall

Lima, La Paz, Cusco, Sacred Valley, Machu Picchu, Arequipa, Colca Canyon, Puno, Copacabana

Duration20 days

From

USD 5,865

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Super Sales

Galapagos Encounter - Archipel I (Itinerary A) - October 2025

No booking fees

Best price guaranteed

This eight-day southwestern tour aboard the catamaran Archipel I gives an extensive overview of the Galapagos by combining the circumnavigation of Isabela Island with excursions in the southernmost points of the archipelago. It also gives the chance to snorkel with sea lions in the Loberia and visit the Charles Darwin Research Station in Santa Cruz.

Wildlife

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

12-99 yrs

Operated in

english

Destinations

Quito, Guayaquil, San Cristobal

Quito, Guayaquil, San Cristobal Island, Santa Fe Island, Floreana Island, Isla Santa Cruz, Isabela Island, Isla Fernandina

Duration10 days

From

USD 8,400

USD 8,148

Saving

USD 252

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Super Sales

Peru Uncovered - October 2025

(1 review )

No booking fees

Best price guaranteed

Initially before booking the trip I thought it was extremely overpriced. However(our tour guide) was fantastic. He made the trip worth every penny and was extremely organised and knowledgeable. The locations were great, and the activities were really cool. was a fantastic character, and became a friend by ensuring we all had fun. He looked after and catered for everyone’s needs and requirements, promoting safety above all else, and more than once went the extra mile to ensure we all had a great time (joining myself at CrossFit and his traditional dance moves were personal highlights). I hope he gets the recognition he deserves, as I would love to book a similar trip with Contiki in future because of this great experience. I would also recommend that you include huacachina in future - I went there on my own and it was one of the coolest experiences - maybe this could be added as an extra at the beginning of the trip.

Adventure

Tour Type

Group Tour

Accommodation

Hotel, Lodge, Home-stay

Age Range

18-35 yrs

Operated in

english

Destinations

Lima, Cusco, Puerto Maldonado, S

Lima, Cusco, Puerto Maldonado, Sacred Valley, Aguas Calientes, Arequipa, Puno

Duration14 days

From

USD 3,877

USD 3,761

Saving

USD 116

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Mountains to the Lakes - October 2025

Trip customizable

Best price guaranteed

This comprehensive 3 week tour is designed to reveal some of the secrets lying in South America. The tour begins in Lima; you then head south for an incredible Ballestas Islands boat trip where you will see exotic birds and sea mammals. You then travel inland to the desert and the palm trees and sand dunes of the Oasis of Huacachina where we make camp under the stars. You will then visit the mysterious Nazca lines whose true meaning is still up for debate. The tour then starts it's ascent into the Andes to the town of Arequipa and the Colca Canyon, the deepest in the world. The tour then takes us to Cuzco where we prepare for the unforgettable Inca Trail, after reaching Machu Picchu we head back to Cuzco for some relaxing time in this beautiful Andean city. We continue our journey to Lake Titicaca where we spend time learning of the traditions of the local Uros Indians, with free time to laze the day away on the shores of this deep blue lake. The tour makes it's final stop in La Paz, giving you free time to explore the Bolivian capital.

Mountains

Tour Type

Small Group Tour

Accommodation

Hotel, Camping, Guest House, Home-stay

Age Range

16-85 yrs

Operated in

english

Destinations

Lima, La Paz, Inca Trail, Machu

Lima, La Paz, Inca Trail, Machu Picchu, Cusco, Puno, Copacabana, Ballestas Islands and Paracas National Reserve, Huacachina, Nazca Lines, Arequipa

Duration21 days

From

USD 4,630

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Machu Picchu by Train - 9 days - October 2025

No booking fees

Best price guaranteed

Discover the incredible highlights of Peru, from the buzzing culinary capital of Lima to the dense bio diverse Amazon Rainforest, on this exciting 9 day tour. Visit sacred sites, colourful markets and travel by scenic train through the Andean Mountains. Explore some of Peru’s most enchanting destinations as you visit the mysterious Inca ruins at Machu Picchu as well as the terraced ruins of Ollantaytambo. Spend two nights in the Amazon Jungle learning about some of the numerous species of birds and animal that live here.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Bungalow

Age Range

18-80 yrs

Operated in

english

Destinations

Cusco, Machu Picchu, Lima, Amazo

Cusco, Machu Picchu, Lima, Amazon Peru, Sacred Valley, Puerto Maldonado

Duration9 days

From

USD 2,605

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All South America Tours in October 2025

Page 59 of 1,743 Trips in South America during October 2025 with 2,405 Reviews

Machu Picchu & Lake Titicaca - 11 days - October 2025

Machu Picchu Express - 5 days - October 2025

Incas, Titicaca & La Paz - 12 days - October 2025

Galapagos Escape - Solaris (Itinerary B) - October 2025

Peru, Canyon & Jungle - 17 days - October 2025

Peru & Iquitos Amazon Cruise - 11 days - October 2025

Luxury Peru & Andean Explorer - 12 days - October 2025

Into the Incan Empire - 8 days - October 2025

Best of Peru & Bolivia - 15 days - October 2025

Peru Encompassed - 20 days - October 2025

Galapagos Encounter - Archipel I (Itinerary A) - October 2025

Peru Uncovered - October 2025

Mountains to the Lakes - October 2025

Machu Picchu by Train - 9 days - October 2025

Page 59 of 1,743 Trips in South America during October 2025 with 2,405 Reviews

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All South America Tours in October 2025

Page 59 of 1,743 Trips in South America during October 2025 with 2,405 Reviews

Page 59 of 1,743 Trips in South America during October 2025 with 2,405 Reviews