10 Best South America Multiday Tours in October 2025

Buenos Aires to Rio de Janeiro (via Uruguay) Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Buenos Aires to Rio de Janeiro, journeying through the captivating landscapes of Uruguay. Discover vibrant cultures, stunning beaches, and iconic landmarks. Highlights include exploring Buenos Aires’ tango-filled streets, soaking in Montevideo’s rich history, and relaxing in Punta del Este’s luxurious resorts. End your trip basking in Rio’s energetic vibe and iconic Christ the Redeemer statue. Perfect for travelers seeking diverse experiences, this South American expedition promises breathtaking sights and unparalleled memories.

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hotel, Resort

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Sa

Buenos Aires, Rio de Janeiro, Sao Paulo, Paraty, Ilha Grande, Colonia, Montevideo, Punta Del Este, Florianopolis

Duration16 days

From

USD 1,372

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Galápagos – Central And East Islands Aboard The Reina Silvia Voyager - October 2025

22% OFF TODAY

Super Sales

Galápagos – Central and East Islands aboard the Reina Silvia Voyager - October 2025

No booking fees

Best price guaranteed

Once you visit these isolated Galápagos Islands that teem with an incredible diversity of marine and animal life, you'll understand what makes them so special. Embark on this eight-day sailing tour onboard the Reina Silvia Voyager, our custom-built catamaran, which offers comfortable accommodations always close by. While exploring the central and eastern Galápagos Islands, you'll witness the giant tortoises of Santa Cruz, spot marine life (including three types of boobies) on the volcanic landscapes of Punta Pitt, and hike along a saltwater lagoon on Rábida.

Marine wildlifeBeach

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

12-100 yrs

Operated in

english

Destinations

Quito, Puerto Ayora, Punta Suáre

Quito, Puerto Ayora, Punta Suárez, Punta Pitt, South Plaza Island, Darwin Bay, Bartolome Island, Chinese Hat

22% OFF TODAY

Duration10 days

From

USD 8,199

USD 6,362

Saving

USD 1,837

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Treasures of Costa Rica - October 2025

4.5

(2 reviews )

Trip customizable

Best price guaranteed

My trip to Costa Rica was excellent and thanks for arranging a fabulous trip. My guide Oscar was probably the best and we really enjoyed the adventure activities. Excellent value for money. Will definitely book again.

Rainforest and jungle visits

Tour Type

Small Group Tour

Accommodation

Hotel, Villa

Age Range

8-99 yrs

Operated in

english

Destinations

San Jose, Manuel Antonio Nationa

San Jose, Manuel Antonio National Park, Arenal Volcano, Arenal, Monteverde, Manuel Antonio

Duration8 days

From

USD 1,154

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Peru Highlights Adventure 14D/13N (from Lima) - October 2025

No booking fees

Best price guaranteed

Discover Peru's hidden gems with a thrilling adventure through breathtaking landscapes and ancient ruins. Explore the iconic Machu Picchu, delve into the mystique of the Amazon Rainforest, and experience vibrant local culture in Cusco. Marvel at the Sacred Valley, cruise on Lake Titicaca, and enjoy scenic train rides and impressive Inca architecture. This immersive journey promises unforgettable memories, perfect for travelers seeking authentic cultural experiences and unparalleled natural beauty. Embark on a Peruvian adventure of a lifetime!

AdventureWalking tours

Tour Type

Small Group Tour

Accommodation

Home-stay, Hotel, Hostel, Bungalow, Hut

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Lima, Puno, Aguas Calient

Cusco, Lima, Puno, Aguas Calientes, Huacachina, Arequipa, Colca Canyon, Amantani

Duration14 days

From

USD 1,437

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The Total Peru Package: Cities, Deserts & Inca Ruins - October 2025

27% OFF TODAY

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The Total Peru Package: Cities, Deserts & Inca Ruins - October 2025

(3 reviews )

No booking fees

Best price guaranteed

The experience was overall amazing, I went to so many places and saw so many things. I always felt safe and enjoyed making friends! Just a shame about having a cold shower and having to use other people?s toilets for a while!

City sightseeing

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel, Hut

Age Range

18-35 yrs

Operated in

english

Destinations

Cusco, Lima, Huacachina, Ollanta

Cusco, Lima, Huacachina, Ollantaytambo, Aguas Calientes

27% OFF TODAY

Duration11 days

From

USD 1,429

USD 1,039

Saving

USD 390

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Galápagos — South & East Islands Aboard The Eden - October 2025

32% OFF TODAY

Super Sales

Galápagos — South & East Islands aboard the Eden - October 2025

(4 reviews )

No booking fees

Best price guaranteed

We had a fantastic time in the Galapagos. This was our second tour with G adventures and both have run very smoothly from a logistics perspective. The Galapagos tour was packed full of activities and everything you could ever want/need was taken care of so you can just enjoy the islands/snorkelling. We had a great team of G adventures staff looking after us, and can?t wait to go back one day to see the rest of the islands.

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel, Yacht Cabin

Age Range

12-100 yrs

Operated in

english

Destinations

Quito, Isla Santa Cruz, Floreana

Quito, Isla Santa Cruz, Floreana Island, Espanola Island, San Cristobal Island, South Plaza Island

32% OFF TODAY

Duration8 days

From

USD 4,279

USD 2,905

Saving

USD 1,374

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The Essence of Costa Rica: Pure Nature - October 2025

Trip customizable

Best price guaranteed

On this immensely popular 10-day vacation package, you’ll have the opportunity to visit the highlands of Costa Rica including tropical jungles, cloud forests, and even a visit to one of the most active volcanoes in the world, Arenal. Head from San Jose to the Osa Peninsula, a destination popular with eco-tourists due to its biodiversity and stunning beauty. There are a variety of exciting activities and excursions to do on the Osa Peninsula and it is a perfect place for all kinds of water sports such as swimming, diving,, and snorkeling in crystal clear Pacific waters. Start in Corcovado National Park where you can enjoy a full-day tour experiencing vibrant flora and fauna unseen in other parts of the world. There are even a few endangered jaguars in the park! Then stay on Cano Island before heading to the famed Arenal Volcano. Here, visit the hot springs and then choose one of three exciting excursions. After Arenal, enjoy some adventure activities and a few nights in the lush Monteverde cloud forest. This is an excellent itinerary for anyone who appreciates the generosity and beauty of nature. Book now!

Nature and bush walks

Tour Type

Group Tour

Accommodation

Eco Lodge, Hotel, Lodge, Resort

Age Range

18-79 yrs

Operated in

english, spanish

Destinations

San Jose, Arenal Volcano, Corcov

San Jose, Arenal Volcano, Corcovado National Park, Arenal Volcano National Park, Monteverde Cloud Forest Biological Preserve

Duration10 days

From

USD 3,795

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Inca Trail to Machu Picchu 4 days with Vistadome Train - October 2025

(8 reviews )

Trip customizable

Best price guaranteed

As our guide would say "The point is this, my friends"... and the day begins. This was one of the best experience I have had. Our guide - Gary - made sure we were on schedule on the trek. He explained to us all the pros and cons and how to get the most out of the Inca Trail. The porters were great. The chef - Julio - made the best camp meals for vegetarians. The scenery is breathtaking. Yes it may seem long and a lot of walking but its worth it. The team made the whole journey worthwhile - from booking to the end. Rosmel - our booking contact kept us informed all the time. Don't hesitate, just do it. Great guide, chef and company. Mahesh

Trekking and HikingAdventure

Tour Type

Small Group Tour

Accommodation

Camping, Hotel, Tent

Age Range

1-75 yrs

Operated in

english, spanish

Destinations

Machu Picchu, Ayapata District

Machu Picchu, Ayapata District, Chaquicocha, Wiñay Wayna, Cusco

Duration4 days

From

USD 800

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Super Sales

Galapagos Wildlife Cruise (Archipel I) - October 2025

4.8

(25 reviews )

No booking fees

Best price guaranteed

If you are reading this then the answer is YES! Yes you should go to the Galapagos islands, it is even more special and magical than you could ever imagine. For me it was a dream come true and the best experience of my life so far. I would 100% recommend this trip and Exodus, so much so that I have already started saving to do it all over again!

WildlifeBird watching

Tour Type

Small Group Tour

Accommodation

Ship Cabin, Hotel

Age Range

12-99 yrs

Operated in

english

Destinations

Quito, Guayaquil, San Cristobal

Quito, Guayaquil, San Cristobal Island, Sante Fe, Isla Santa Cruz, Isabela Island, Isla Santiago, Baltra Island, Genovesa Island, Santa Cruz, Floreana Island, Espanola Island

Duration17 days

From

USD 15,750

USD 15,278

Saving

USD 473

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Bolivia Expedition - October 2025

Trip customizable

Best price guaranteed

Bolivia is a geographically diverse country and is often referred to as the Tibet of South America. On this guided tour, explore the natural splendor of the Andean landscape and gain a deeper understanding of the complex contemporary culture of the region. Walk the streets of La Paz, a city that touches the sky, and roam through its most important squares and attractions. Visit the city of Sucre, which is Bolivia’s most beautiful city and the symbolic heart of the nation. It was here that independence was proclaimed. Explore the Uyuni and its Colchani village, Incahuasi Island, famous for its soaring cacti, and the Chiguana salt flat. Highlight of Uyuni is the Red Lagoon and its blood-red tint. Also, get a deeper understanding of pre-Incan culture of the region at Tiwanaku.

Cultural, religious and historic sites

Tour Type

Group Tour

Accommodation

Guest House, Hotel

Age Range

12-73 yrs

Operated in

english, spanish

Destinations

La Paz, Uyuni, Sucre, Valle De L

La Paz, Uyuni, Sucre, Valle De La Luna, Potosi

Duration8 days

From

USD 2,099

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Full Day Tour Valparaiso, Viña del Mar and Casablanca - October 2025

(3 reviews )

Trip customizable

Best price guaranteed

The tour company left a message at our hotel telling us what time they would pick us up the next day. They were exactly on time which was great. Our tour guide (Frank) was absolutely wonderful. So informative and he spoke english and spanish so well. I liked the fact there were only about 7 or 8 in our group too. It meant you had no trouble hearing what was being said. The walking tour of Valparaiso was a great way to see the place and if there was anything anyone in the group particularly wanted to look at it wasn't a problem. Lunch was at your own cost but it was a great restaurant that was chosen with wonderful views of Valparaiso. Visiting Vina Del Mar was good also and finishing the tour with a wine tasting in the Casablanca Valley was the perfect end to the day.

City sightseeingBeach

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-90 yrs

Operated in

english, spanish

Destinations

Santiago, Valparaiso

Duration9 hours

From

USD 130

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22% OFF TODAY

Super Sales

Upgraded Land Galapagos - October 2025

(4 reviews )

No booking fees

Best price guaranteed

Overall experience was fantastic.

WildlifeBeachSnorkeling

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Villa

Age Range

12-100 yrs

Operated in

english

Destinations

Quito, Galapagos Islands, San Cr

Quito, Galapagos Islands, San Cristobal Island, Floreana Island, Isabela Island, Puerto Ayora, Papallacta

22% OFF TODAY

Duration10 days

From

USD 4,449

USD 3,452

Saving

USD 997

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Colombia's Lost City Trek - October 2025

(1 review )

No booking fees

Best price guaranteed

Wow - this was a challenging hike! Not so much the terrain, definitely due to the hot weather. Putting the heat, sweat and fatigue to one side - this hike is unique and rewarding. Along the route there is lots to see and the destination is mind blowing! Our team (Stiwen, Brayan & Pinnochio) were attentive and did everything possible to make this a safe & memorable trip. The side journeys on this itinerary were all worthwhile and enjoyable. It was just the two of us for the duration of this trip and at all times we felt safe and everything ran without a hitch.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Resort, Camping

Age Range

18-99 yrs

Operated in

english

Destinations

Bogota, Cartagena, The Lost City

Bogota, Cartagena, The Lost City Trek, Santa Marta

Duration10 days

From

USD 2,290

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Treasures of Patagonia - October 2025

(7 reviews )

Trip customizable

Best price guaranteed

All in great company and superbly organised. I was travelling solo and the guide and group made me feel hugely welcome.

Active and outdoor

Tour Type

Private Tour

Accommodation

Hotel, Tent, Camping

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

El Calafate, El Chalten, Patagon

El Calafate, El Chalten, Patagonia, Perito Moreno Glacier

Duration6 days

From

USD 2,485

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All South America Tours in October 2025

Page 18 of 1,738 Trips in South America during October 2025 with 2,452 Reviews

Buenos Aires to Rio de Janeiro (via Uruguay) Travel Pass - October 2025

Galápagos – Central and East Islands aboard the Reina Silvia Voyager - October 2025

Treasures of Costa Rica - October 2025

Peru Highlights Adventure 14D/13N (from Lima) - October 2025

The Total Peru Package: Cities, Deserts & Inca Ruins - October 2025

Galápagos — South & East Islands aboard the Eden - October 2025

The Essence of Costa Rica: Pure Nature - October 2025

Inca Trail to Machu Picchu 4 days with Vistadome Train - October 2025

Galapagos Wildlife Cruise (Archipel I) - October 2025

Bolivia Expedition - October 2025

Full Day Tour Valparaiso, Viña del Mar and Casablanca - October 2025

Upgraded Land Galapagos - October 2025

Colombia's Lost City Trek - October 2025

Treasures of Patagonia - October 2025

Page 18 of 1,738 Trips in South America during October 2025 with 2,452 Reviews

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Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All South America Tours in October 2025

Page 18 of 1,738 Trips in South America during October 2025 with 2,452 Reviews

Page 18 of 1,738 Trips in South America during October 2025 with 2,452 Reviews