10 Best South America Multiday Tours in October 2025

Salkantay Backpacker Trek to Machu Picchu 5D/4N - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable 5-day journey from the vibrant city of Cusco through the mesmerizing Andes, experiencing breathtaking highland treks, mystical lagoons, verdant jungles, and the awe-inspiring ancient ruins of Machu Picchu. Embrace a myriad of landscapes and cultural encounters, culminating in the ultimate exploration of the Lost City at sunrise.

ExplorerAdventure

Tour Type

Small Group Tour

Accommodation

Camping, Hostel, Tent

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Soraypampa, Colcapampa, S

Cusco, Soraypampa, Colcapampa, Santa Teresa, Aguas Calientes

Duration5 days

From

USD 483

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Huayhuash Express 6D/5N - October 2025

No booking fees

Best price guaranteed

Embark on a breathtaking trekking adventure through the stunning Peruvian Andes with this all-inclusive Huayhuash circuit. Traverse picturesque landscapes, encounter crystal-clear alpine lakes, and gain exclusive insights into local culture. Perfect for avid hikers seeking an unforgettable, high-altitude experience, this guided expedition offers challenging trails and awe-inspiring vistas. With experienced guides, delicious meals, and comfortable campsites, immerse yourself in nature's splendor while creating lifelong memories on this top-rated trek in Peru's renowned mountain sanctuary.

AdventureTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Tent, Camping, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Huaraz, Matacancha, Laguna Jahuacocha

Duration6 days

From

USD 1,457

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Salkantay, Humantay Lake & Machu Picchu Adventure 3D/2N - October 2025

No booking fees

Best price guaranteed

Trek past turquoise lakes, snow-capped peaks, and starlit domes before discovering the legendary citadel of Machu Picchu on this unforgettable adventure.

Skiing and Snowboarding

Tour Type

Small Group Tour

Accommodation

Hotel, Camping

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Rajasthan, Machu Picchu

Duration3 days

From

USD 505

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Lima to Rio de Janeiro (via Pantanal) Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Peru to Brazil, traversing breathtaking landscapes and diverse cultures. Discover the vibrant city of Lima, explore the mystical ruins of Machu Picchu, and experience the natural wonders of the Pantanal, the world’s largest tropical wetland. Enjoy wildlife spotting, scenic hikes, and cultural immersion as you journey to the iconic Rio de Janeiro. This expertly curated route promises unparalleled encounters with nature and local traditions, perfect for nature enthusiasts and cultural explorers alike.

Walking toursSightseeing Tours

Tour Type

Group Tour

Accommodation

Hostel, Hut, Home-stay, Bungalow, Hotel, Lodge, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Arequipa

Rio de Janeiro, Lima, Arequipa, Cusco, Luquina, Puno, Copacabana, La Paz, Paracas, Candelaria, Polques, Uyuni, Potosi, Sucre, Santa Cruz, Puerto Quijarro, Corumba, Pantanal, Bonito, Campo Grande, Sao Paulo, Huacachina, Paraty, Ilha Grande, Nazca, Colca Canyon

Duration46 days

From

USD 3,809

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Cuzco to Lima Express Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure through Peru’s iconic landscapes with this thrilling travel pass from Cuzco to Lima. Discover the rich history of the Sacred Valley, the mesmerizing beauty of Machu Picchu, and the vibrant culture of Lima. Enjoy guided tours, scenic bus rides, and immersive cultural experiences. Perfect for adventurers and history enthusiasts, this package offers a seamless blend of majestic ruins, breathtaking scenery, and local traditions. Witness Peru’s magic unfold on this ultimate exploration journey.

SandboardingExplorer

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Lima, Paracas, Puno, Areq

Cusco, Lima, Paracas, Puno, Arequipa, Nazca, Huacachina

Duration12 days

From

USD 864

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Puerto Maldonado Amazon Superior Lodge 5D/4N (from Puerto Maldonado) - October 2025

No booking fees

Best price guaranteed

Discover the breathtaking beauty of the Amazon Rainforest in Puerto Maldonado with an unforgettable eco-adventure. Experience guided wildlife treks, canopy walks, and river excursions that reveal rare Amazonian species and stunning landscapes. Enjoy luxurious accommodations at a superior lodge, savor local Peruvian cuisine, and immerse yourself in indigenous culture. Perfect for nature enthusiasts and adventure seekers, this Amazon journey offers profound insights into this diverse ecosystem, ensuring a once-in-a-lifetime experience in the heart of the jungle.

AdventureExplorer

Tour Type

Small Group Tour

Accommodation

Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

Puerto Maldonado, Amazon Jungle

Duration5 days

From

USD 1,190

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Sacred Valley Day Trek - October 2025

No booking fees

Best price guaranteed

Discover the breathtaking beauty of Peru's Sacred Valley with an exhilarating trek that immerses you in ancient Inca culture and stunning landscapes. Explore historic ruins, vibrant local markets, and picturesque villages set against majestic Andean peaks. Enjoy guided tours to iconic sites like Ollantaytambo and Pisac, while experiencing authentic Andean traditions. Perfect for adventure seekers and history enthusiasts, this unforgettable journey offers a unique blend of natural splendor and cultural richness in one of the world's most enchanting destinations.

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco

Duration11 hours

From

USD 85

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Bolivian Amazon Pampas Adventure 3D/2N (from Rurrenabaque) - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable Bolivian Amazon adventure from Rurrenabaque! Discover the vibrant Pampas teeming with exotic wildlife, including pink river dolphins, capybaras, and caimans. Enjoy captivating activities like piranha fishing, guided hikes, and thrilling boat excursions through lush riverine forests. Savor the authentic Amazonian experience with comfortable eco-lodge accommodations and expert local guides ensuring an immersive, safe, and enriching journey. Perfect for nature enthusiasts seeking an eco-friendly expedition in one of the world's most biodiverse regions.

Adventure

Tour Type

Small Group Tour

Accommodation

Hostel, Lodge, Eco Lodge, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Rurrenabaque

Duration3 days

From

USD 381

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Machu Picchu by Train Adventure - October 2025

No booking fees

Best price guaranteed

Immerse yourself in the captivating world of the Incas with this unforgettable journey to Machu Picchu. Begin your adventure in Cusco, travel through the scenic Sacred Valley, and arrive at the awe-inspiring Inca Citadel. With expert local guides, explore the ancient marvel, indulge in a gourmet lunch, and return with memories etched in time.

Trekking and HikingTrain tours

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco

Duration19 hours

From

USD 532

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Lima to Buenos Aires (via Chile) Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on a captivating South American adventure traversing the vibrant landscapes of Lima, Santiago, and Buenos Aires. This immersive journey takes you through Peru, Chile, and Argentina, offering unique experiences such as exploring the Sacred Valley, witnessing the surreal beauty of the Atacama Desert, and savoring world-renowned Chilean wines. Discover the rich cultural heritage of each city, from Lima's historic center to Buenos Aires' tango-filled streets. Ideal for adventurers and culture enthusiasts seeking an unforgettable travel experience.

City sightseeingLocal culture

Tour Type

Group Tour

Accommodation

Hostel, Hut, Home-stay, Bungalow, Hotel, Lodge, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Lima, Arequipa, Cu

Buenos Aires, Lima, Arequipa, Cusco, Luquina, Puno, Copacabana, Paracas, La Paz, Sucre, Potosi, Uyuni, Candelaria, Polques, San Pedro De Atacama, Calama, Valparaiso, Santiago, Mendoza, Córdoba, Huacachina, Colca Canyon

Duration41 days

From

USD 2,771

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Chili River Rafting - October 2025

No booking fees

Best price guaranteed

Discover adrenaline-pumping adventure with an exhilarating rafting experience on the Chili River in Peru! Navigate thrilling rapids set against the stunning backdrop of the Andes Mountains. This unforgettable white-water journey offers a blend of natural beauty, heart-racing excitement, and expert-guided safety. Perfect for both novice and seasoned rafters, this Peru rafting tour promises lasting memories. Join us for a unique outdoor escapade and immerse yourself in this South American gem. Book now for an epic adventure!

RaftingAdventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Arequipa

Duration3 hours

From

USD 33

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Colca Canyon Trekking 2D/1N - October 2025

No booking fees

Best price guaranteed

Explore breathtaking Colca Canyon with an unforgettable 2-day trekking adventure. Immerse yourself in the stunning landscapes of one of the world's deepest canyons, spot majestic Andean condors soaring above, and visit traditional Peruvian villages. This exhilarating hike includes guided treks, cultural encounters, and unparalleled natural beauty. Perfect for adventure seekers and nature lovers, this tour blends excitement with authentic local experiences, ensuring a memorable journey through Peru's awe-inspiring Colca Canyon. Book now for an unparalleled escapade!

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Bungalow, Guest House

Age Range

18-99 yrs

Operated in

english

Destinations

Arequipa, Sangalle

Duration2 days

From

USD 126

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Iquitos Amazon Jungle Adventure 5D/4N - October 2025

No booking fees

Best price guaranteed

Discover an unforgettable Amazon jungle adventure in Iquitos, offering immersive wildlife encounters, guided rainforest hikes, and serene boat tours. This tour includes vibrant visits to native communities, exploration of exotic flora and fauna, and fascinating night safaris. Guests can enjoy comfortable accommodations while experiencing the pristine beauty of the Amazon River and its rich biodiversity. Ideal for nature enthusiasts and adventurous travelers looking for a unique, eco-friendly escape in the heart of the Peruvian Amazon.

ExplorerAdventure

Tour Type

Small Group Tour

Accommodation

Lodge, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Amazon Peru, Iquitos, Amazon Lod

Amazon Peru, Iquitos, Amazon Lodge Tambopata, Lima

Duration5 days

From

USD 879

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Iquitos Amazon Jungle Adventure 3D/2N - October 2025

No booking fees

Best price guaranteed

Explore the heart of the Peruvian Amazon with a thrilling jungle adventure in Iquitos. Experience exotic wildlife, guided hikes, and canoe trips through lush rainforests. Marvel at diverse flora and fauna, spot pink river dolphins, and visit indigenous communities. This immersive Amazon journey offers unparalleled opportunities for nature photography and birdwatching. Adventure-seekers and nature enthusiasts will love the unique blend of cultural encounters and breathtaking natural scenery. Book now for a memorable eco-tourism experience in one of the world's most biodiverse regions!

ExplorerAdventure

Tour Type

Small Group Tour

Accommodation

Lodge, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Amazon Peru, Iquitos, Lima

Duration3 days

From

USD 600

View Tour

All South America Tours in October 2025

Page 28 of 515 Trips in South America during October 2025 with 1,053 Reviews

Salkantay Backpacker Trek to Machu Picchu 5D/4N - October 2025

Huayhuash Express 6D/5N - October 2025

Salkantay, Humantay Lake & Machu Picchu Adventure 3D/2N - October 2025

Lima to Rio de Janeiro (via Pantanal) Travel Pass - October 2025

Cuzco to Lima Express Travel Pass - October 2025

Puerto Maldonado Amazon Superior Lodge 5D/4N (from Puerto Maldonado) - October 2025

Sacred Valley Day Trek - October 2025

Bolivian Amazon Pampas Adventure 3D/2N (from Rurrenabaque) - October 2025

Machu Picchu by Train Adventure - October 2025

Lima to Buenos Aires (via Chile) Travel Pass - October 2025

Chili River Rafting - October 2025

Colca Canyon Trekking 2D/1N - October 2025

Iquitos Amazon Jungle Adventure 5D/4N - October 2025

Iquitos Amazon Jungle Adventure 3D/2N - October 2025

Page 28 of 515 Trips in South America during October 2025 with 1,053 Reviews

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All South America Tours in October 2025

Page 28 of 515 Trips in South America during October 2025 with 1,053 Reviews

Page 28 of 515 Trips in South America during October 2025 with 1,053 Reviews