10 Best South America Multiday Tours in April 2026

Accommodations

BudgetSimple stays with essential amenities. Typically guesthouses, hostels or hotels rated below 3 stars — clean, no-frills, and great for value-conscious travelers.
Mid-rangeComfortable and reliable 3-star stays. Expect private rooms, en-suite bathrooms, and solid amenities — a great balance between comfort and cost.
PremiumUpscale 4-5 star hotels and lodges. Enjoy high-end service, refined comfort, and premium locations — ideal for travelers seeking extra indulgence.

Iquitos Amazon Jungle Adventure 4D/3N - April 2026

No booking fees

Best price guaranteed

Embark on an enthralling Amazon rainforest adventure with breathtaking wildlife encounters and guided jungle treks. Explore Iquitos' vibrant river life, visit indigenous communities, and cruise along the Amazon River spotting exotic animals. Delight in night safaris, canopy walks, and piranha fishing, all while surrounded by lush, unspoiled nature. Perfect for nature enthusiasts and thrill-seekers alike, this immersive tour promises a unique and unforgettable experience in one of the world's most biodiverse regions. Secure your jungle escape today!

ExplorerAdventure

Tour Type

Small Group Tour

Accommodation

Lodge, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Amazon Peru, Iquitos, Lima

Duration4 days

From

USD 750

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Buenos Aires Walking City Tour - April 2026

Trip customizable

Best price guaranteed

The Walking Tour of Buenos Aires is the best way to get to know the city. Our tour is done walking and traveling by public transportation. The idea is to get to know, in a sustainable way and without losing sight of the daily reality of the porteños, the most beautiful and interesting corners of the city. We go out with small groups prioritizing the quality of the excursion. You will experience a unique and real contact experience with our beloved metropolis, visiting the Downtown and its Historical Center, San Telmo, La Boca and Recoleta

City sightseeingWalking tours

Tour Type

Group Tour

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires

Duration1 day

From

USD 142

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Shore Excursion: Peninsula Valdes Day Trip - April 2026

Trip customizable

Best price guaranteed

Explore the impressive Valdes Peninsula, a UNESCO World Heritage Site, on this full-day tour from Puerto Madryn. This geographic formation is famous for being an ideal breeding ground for certain species of marine fauna, including the southern right whales and various species of dolphins. On this day in the middle of nature, you will be accompanied by bilingual guides and naturalists. We also include transfers from Luis Piedrabuena bridge (at the cruise ship)

Natural landmarks sightseeing

Tour Type

Small Group Tour

Age Range

1-99 yrs

Operated in

english

Destinations

Puerto Madryn

Duration1 day

From

USD 160

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Shared Transfer - Santiago Airport to Hotel - April 2026

No booking fees

Best price guaranteed

Santiago has become one of the "top" cities in business opportunities and has built an image of tranquility, cleanliness and quality of life valued by visitors. According to the prestigious American newspaper The New York Times, Santiago de Chile is the best travel destination for 2011. Your best bet as a traveler still walk its streets and discover a metropolis increasingly renewing its spaces. Leave the driving in foreign cities to a professional and let our driver transport you safely from Santiago Airport to your Hotel in Santiago. Start your trip off right with our stress free airport transportation services. A representative will greet you at Santiago International Airport and take you to your selected hotel. In the road you can see more about Santiago main highlights. Enjoy the ride and soak in the sights!

Self-drive or vehicle rental

Tour Type

Private Tour

Accommodation

Hotel

Age Range

1-79 yrs

Operated in

english, portuguese, spanish

Destinations

Santiago

Duration1 hour

From

USD 35

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Colca Canyon Sightseeing Tour 2D/1N & Transfer to Puno - April 2026

No booking fees

Best price guaranteed

Discover the breathtaking beauty of Colca Canyon with this captivating sightseeing adventure. Traverse through picturesque landscapes, witness the graceful flight of majestic condors, and immerse yourself in the rich culture of traditional Peruvian villages. This tour offers a seamless transfer to Puno, providing convenience and unparalleled scenic views. Ideal for nature lovers and cultural enthusiasts, this unforgettable journey promises stunning vistas, wildlife encounters, and vibrant local experiences in one of Peru's most iconic destinations.

Trekking and HikingAdventure

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Puno, Arequipa, Chivay

Duration2 days

From

USD 190

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Sacred Valley Tour & Short Inca Trail 3 Days - April 2026

(2 reviews )

Trip customizable

Best price guaranteed

This travel operator provided us with a two-day trek to Machu Picchu that has to be experienced to be truly understood. Their crew of porters and cook provided exceptional service and meals. David's knowledge was outstanding and his attention to detail in regards to accommodation travel and gear storage was second to none. If you want a first class trekking experience this company should be your first choice.

Sightseeing ToursAdventure

Tour Type

Private and Group Tour

Accommodation

Hotel

Age Range

6-75 yrs

Operated in

english, spanish

Destinations

Inca Trail, Machu Picchu, Sacred

Inca Trail, Machu Picchu, Sacred Valley, Ollantaytambo, Cusco

Duration3 days

From

USD 690

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Super Sales

Galapagos Encounter: Southern Islands (Grand Queen Beatriz) - April 2026

No booking fees

Best price guaranteed

Tick the Galapagos off your list on this week-long sailing voyage that takes in the very best of the southern islands. Rub shoulders with the local wildlife as sea lions, iguanas, giant tortoises and exotic birds of all shapes and sizes go about their daily business. Go snorkelling near mighty manta rays, turtles and tropical fish fill. Experience firsthand the natural, rugged landscapes of the Galapagos and see what Charles Darwin saw when he arrived on the isles more than 180 years ago and go hiking to discover the changing and unique landscapes of this incredible part of the world.

Sailing, yachting and motor boating

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

12-99 yrs

Operated in

english

Destinations

Quito, Baltra Island, Isla Isabe

Quito, Baltra Island, Isla Isabela, Floreana Island, Isla Santa Cruz

Duration6 days

From

USD 3,740

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Ecuador Volcanoes Adventure 5D/4N - April 2026

No booking fees

Best price guaranteed

Embark on an exhilarating Ecuador adventure exploring stunning volcanoes and pristine landscapes. Experience captivating hikes through Cotopaxi National Park, marvel at the breathtaking Quilotoa Crater Lake, and discover the vibrant cultures of Andean villages. This journey promises unforgettable moments, from horseback riding across scenic highlands to relaxing in natural hot springs. Perfect for nature lovers and thrill-seekers, this tour immerses you in Ecuador's natural wonders and rich cultural heritage. Book now for an extraordinary volcanic escapade!

AdventureTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Quito, Isinlivi, Chugchilán

Duration5 days

From

USD 891

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Super Sales

Essential South, Private Tour - April 2026

Trip customizable

Best price guaranteed

Enjoy the best of Peru during this round-trip tour beginning in beautiful Lima and ending with a drop-off at the Puno airport. Spend nine memorable days in this stunning country, visit charming colonial cities, learn about the legacy of ancient civilisations, and explore some of the most spectacular landscapes on the planet. Meet the descendants of the Incas and the camelids of the Andes. Discover the Sacred Valley of the Incas, observe the shadows of the past surrounding the islands of Lake Titicaca. Then, enjoy a pilgrimage to the peaks of the Andes to tour the magnificent citadel and mountain of Machu Picchu.

Art and architecture

Tour Type

Private Tour

Accommodation

Hotel

Age Range

6-99 yrs

Operated in

english, spanish, french, portuguese

Destinations

Lima, Cusco, Ollantaytambo, Agua

Lima, Cusco, Ollantaytambo, Aguas Calientes, Puno

Duration9 days

From

USD 1,602

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Super Sales

Arequipa And Colca Canyon, Private Tour - April 2026

Trip customizable

Best price guaranteed

Explore Arequipa, the second largest city in Peru, during an awe-inspiring four-day tour. Visit its colonial-style downtown, admire its beautiful churches and catch a glimpse of the pampas outside the city, enjoying the spectacular scenery. Let the graceful flight of the condor entertain you in the Colca Valley and admire the native camelids of the Andes. Join this interesting tour and catch sight of the beautiful nature and interesting Peruvian culture.

Art and architecture

Tour Type

Private Tour

Accommodation

Hotel, Lodge

Age Range

6-99 yrs

Operated in

english, spanish, french, portuguese

Destinations

Arequipa, Colca Canyon

Duration4 days

From

USD 632

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island hopping Galapagos - April 2026

Trip customizable

Best price guaranteed

Experience 4 of the famous Galapagos islands and the unique flora and fauna of the area on this 7-day trip. Discovering Galapagos with our island-hopping tour allows you to really get in touch with the islands. Take advantage of free time after your tours for wandering around the pier, enjoying local food in nice restaurants, observing fisher boots in the harbour, etc. The Islands offer beautiful and unique landscapes as well as a bright range of biodiversity. The most popular animals from the islands are iguanas, sea lions and giant turtles, as well as a range of beautiful birds. The islands also offer great hiking possibilities with views over the whole area. The tour is ideal for people who love to discover even beyond the scheduled excursions. With our daily WhatsApp coaching and special hints for your free time, you'll get to know Galapagos at its best.

National parksWildlife

Tour Type

Group Tour

Accommodation

Hotel

Age Range

1-79 yrs

Operated in

english

Destinations

Quito, Galapagos Islands, Darwin

Quito, Galapagos Islands, Darwin Bay, Playa Ochoa, Tortuga Bay, Bartolome Island

Duration7 days

From

USD 2,190

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Estancia Cristina & Fossil Canyon Trek - April 2026

Trip customizable

Best price guaranteed

This tour it's an adventure like no other. It will take you to travel in 4x4 vehicles a mountain road that used to be hidden by the presence of glaciers, to reach the refuge of Continental Icefield and from there, make a trek through the most beautiful landscapes ever seen.With our tour Estancia Cristina Trekking Canyon of Fossils, you can see landmarks such as the Mirador del Upsala and its imposing eastern front, Lago Guillermo, Hielo Patagónico Sur, and Cerros Murallón and Don Bosco, to finish at the amazing Canyon of Fossil

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

12-99 yrs

Operated in

english

Destinations

Patagonia, El Calafate

Duration1 day

From

USD 513

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Gourmet food tour in Miraflores and Barranco - April 2026

Trip customizable

Best price guaranteed

Peru has one of the most relevant gastronomies in the world, and with our Tour Gourmet - Lima Night, you’ll have a funny and a unique experience. Enjoy an explosion of flavors with this night tour, visiting part of the wonderful city of Lima, and exploring places with traditional and exquisite food

Food tours

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Lima

Duration1 day

From

USD 201

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Lake Titicaca & Luquina Homestay 2D/1N - April 2026

No booking fees

Best price guaranteed

Embark on a captivating journey across Lake Titicaca's stunning landscapes, immersing yourself in the vibrant culture and traditions of the unique floating islands and Taquile community. Witness the exceptional craftsmanship of local weavers, experience a genuine cultural exchange with the welcoming Luquina community, and embrace the tranquillity of life on the lake.

Getaways and short breaks

Tour Type

Small Group Tour

Accommodation

Home-stay, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Puno, Lake Titicaca, Amantani

Duration2 days

From

USD 110

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All South America Tours in April 2026

Page 32 of 1,381 Trips in South America during April 2026 with 3,655 Reviews

Iquitos Amazon Jungle Adventure 4D/3N - April 2026

Buenos Aires Walking City Tour - April 2026

Shore Excursion: Peninsula Valdes Day Trip - April 2026

Shared Transfer - Santiago Airport to Hotel - April 2026

Colca Canyon Sightseeing Tour 2D/1N & Transfer to Puno - April 2026

Sacred Valley Tour & Short Inca Trail 3 Days - April 2026

Galapagos Encounter: Southern Islands (Grand Queen Beatriz) - April 2026

Ecuador Volcanoes Adventure 5D/4N - April 2026

Essential South, Private Tour - April 2026

Arequipa And Colca Canyon, Private Tour - April 2026

island hopping Galapagos - April 2026

Page 32 of 1,381 Trips in South America during April 2026 with 3,655 Reviews

Estancia Cristina & Fossil Canyon Trek - April 2026

Gourmet food tour in Miraflores and Barranco - April 2026

Lake Titicaca & Luquina Homestay 2D/1N - April 2026

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Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All South America Tours in April 2026

Page 32 of 1,381 Trips in South America during April 2026 with 3,655 Reviews

Page 32 of 1,381 Trips in South America during April 2026 with 3,655 Reviews