10 Best Santiago Multiday Tours in October 2026

Rio de Janeiro to Santiago Travel Pass - October 2026

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Rio de Janeiro to Santiago, exploring South America’s vibrant culture and breathtaking landscapes. Dive into lively Rio’s beaches, marvel at Iguazu Falls’ natural wonders, and revel in Buenos Aires’ rich history. Experience Chile’s scenic beauty in Colchagua Valley and the energetic atmosphere of Santiago. Perfect for thrill-seekers and cultural enthusiasts, enjoy unique excursions including wine tasting and tango dancing lessons. Discover the essence of South America with this curated travel experience.

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro, Floria

Santiago, Rio de Janeiro, Florianopolis, Foz Do Iguacu, Puerto Iguazu, Buenos Aires, Córdoba, Mendoza, Ilha Grande, Paraty, Sao Paulo

Duration21 days

From

USD 1,779

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Atacama & the North - 10 Days - October 2026

No booking fees

Best price guaranteed

Get off the beaten track in Chile’s northern reaches with this unique adventure through the Atacama Desert. Kicking off in Santiago discover fascinating museums, lunar-like landscapes of geysers and rock formations, pre-Hispanic ruins and gigantic geoglyphs, mammoth copper mines and abandoned ghost towns with plenty of natural beauty to boot.

Art and architecture

Tour Type

Private Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Santiago, Arica, San Pedro De At

Santiago, Arica, San Pedro De Atacama, Atacama Desert, El Tatio, Iquique, Putre

Duration10 days

From

USD 7,015

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Super Sales

Grand South America - October 2026

(1 review )

No booking fees

Best price guaranteed

was a great tour director made sure about everyone needs

City sightseeing

Tour Type

Group Tour

Accommodation

Hotel, Resort

Age Range

5-99 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Lake Titic

Rio de Janeiro, Lima, Lake Titicaca, Santiago, Valparaiso, Buenos Aires, Pampas, Iguassu National Park, Iguassu National Park, Cusco, Sacred Valley, Machu Picchu, Puno

Duration23 days

From

USD 16,821

USD 16,316

Saving

USD 505

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Super Sales

Premium Highlights of South America - October 2026

No booking fees

Best price guaranteed

Experience the diversity of wonders across Peru, Chile, Argentina and Brazil on a 24-day Premium journey. Be immersed in the ancient culture of the Incas, visit the Amazon Jungle and revel in the magnificent citadel ruins of Machu Picchu. Soak up the energy of Santiago and Buenos Aires’ lively neighbourhoods and sip some of the world’s best wine in Mendoza. At the border with Brazil, experience the magnificent might of Iguazu Falls, before finally arriving in one of the most beautiful cities in the world, Rio de Janeiro. With the guidance of passionate local leaders, you’ll find out South America dances to the beat of its own drum.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Resort

Age Range

15-99 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Santiago

Rio de Janeiro, Lima, Santiago, Valparaiso, Mendoza, Buenos Aires, Puerto Maldonado, Puerto Iguazu, Amazon Lodge Tambopata, Cusco, Ollantaytambo, Machu Picchu

Duration24 days

From

USD 15,815

USD 15,341

Saving

USD 474

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13% OFF TODAY

Super Sales

Wonders of Patagonia - October 2026

4.2

(11 reviews )

No booking fees

Best price guaranteed

Cave could be missed and more time in National Park otherwise excelent. was great.

GlaciersNational parks

Tour Type

Group Tour

Accommodation

Hotel

Age Range

5-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Puerto N

Buenos Aires, Santiago, Puerto Natales, Ushuaia, El Calafate, Los Glaciares National Park, Torres del Paine National Park

13% OFF TODAY

Duration11 days

From

USD 6,954

USD 6,023

Saving

USD 931

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Patagonian Explorer Cruise - October 2026

Trip customizable

Best price guaranteed

This land and cruise tour will take you to see the marvels of two iconic South American cities and to the Fjords of Tierra del Fuego in Patagonia. Start this adventure in Santiago, a beautiful cosmopolitan city where you will see Santiago’s most important sites like Plaza de Armas, Modena Palace, Santa Lucía Hill and Barrio Lastarria, the latest is famous for the cultural, inherited and gastronomical options. Continue to Punta Arenas from where you will board your cruise to explore Patagonia. During this cruise you will see the fjords of the southern edge of Tierra del Fuego. Sail the Strait of Magellan into the labyrinth of channels from where you will see the highlights and most important sites and glaciers of the region, you will also visit Wulaia Bay and Cape Horn, known as the “End of the Earth”. After this wonderful cruise in Patagonia, you will disembark in Ushuaia from where you will fly to your last stop, Buenos Aires where you’ll have the chance to explore many of the city’s intriguing and varied neighbourhoods and learn about their culture and history before your tour ends.

CruiseCity sightseeing

Tour Type

Independent Tour

Accommodation

Hotel, Ship Cabin

Age Range

8-99 yrs

Operated in

English

Destinations

Buenos Aires, Punta Arenas, Ushu

Buenos Aires, Punta Arenas, Ushuaia, Wulaia Bay, Pia Glacier, Cóndor Glacier, Santiago

Duration6 days

From

USD 3,097

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18% OFF TODAY

Argentina, Atacama Desert & Chile Delights - October 2026

(1 review )

No booking fees

Best price guaranteed

Exploring the southern parts of South America has been great.

Cultural, religious and historic sites

Tour Type

Group Tour

Accommodation

Hotel, Sleeper Bus

Age Range

10-99 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro, Foz Do

Santiago, Rio de Janeiro, Foz Do Iguacu, Paraty, Buenos Aires, San Pedro De Atacama, El Tigre, Mendoza

18% OFF TODAY

Duration13 days

From

USD 3,030

USD 2,495

Saving

USD 535

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Patagonia In Style - 14 days - October 2026

No booking fees

Best price guaranteed

Travel in style from Santiago to the southernmost reaches of Chile and Argentina and up to Buenos Aires, staying in superior hotels and taking in Patagonia's striking landscape of towering snow-capped mountains, glacial lakes and fjords and boat ride at beneath the glaciers.

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hotel, Lodge

Age Range

18-80 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Ushuaia

Buenos Aires, Santiago, Ushuaia, Tierra Del Fuego National Park, Valparaiso, Punta Arenas, Torres Del Paine, Glacier Grey, El Calafate, Perito Moreno Glacier, Santiago

Duration14 days

From

USD 8,325

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Santiago to Patagonia - 14 days - October 2026

No booking fees

Best price guaranteed

Discover Chile in all its glorious natural beauty from the glittering lakes of Puerto Varas, the scenic archipelago of Chiloé, the panoramic views from Punta Arenas and the jagged granite peaks of the Paine massif. Along the way visit traditional fishing villages, observe comical penguins and explore Torres del Paine national park in your way.

Sightseeing ToursWaterfalls

Tour Type

Private Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Santiago, Punta Arenas, Torres D

Santiago, Punta Arenas, Torres Del Paine, Puerto Varas, Peulla, Chiloe National Park, Santiago

Duration14 days

From

USD 7,795

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Super Sales

Premium Peru, Chile & Argentina - October 2026

No booking fees

Best price guaranteed

Capture the true essence of South America on an 18-day Premium adventure through Peru, Chile and Argentina. This journey showcases the continent’s diversity of natural beauty, historic wonder and world-class cuisine, passing by the Andes and the Amazon, Mendoza and the majestic Machu Picchu, the Sacred Valley and sultry Santiago, all the way to the Argentinian powerhouse of Buenos Aires. Gain an insight into ancient Inca culture and local communities, indulge in fine food and some of the region’s best wine, and get to the heart of each destination with expert local knowledge at every step.

Natural landmarks sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Resort

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Lima, Santiago, Va

Buenos Aires, Lima, Santiago, Valparaiso, Mendoza, Amazon Jungle, Cusco, Ollantaytambo, Machu Picchu

Duration18 days

From

USD 11,170

USD 10,835

Saving

USD 335

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Essential Argentina And Chile - October 2026

Trip customizable

Best price guaranteed

Discover breathtaking natural wonders and famous cities with this small group tour of Argentina and Chile! Begin your journey in Buenos Aires, the capital of Argentina, to explore the bustling neighborhoods of the city and learn about the local history. Visit La Boca and walk around San Telmo, two of the most famous districts in Buenos Aires. Catch a flight to El Calafate as you cross the border into Chile and discover the Perito Moreno Glacier, one of the largest glaciers in the world. Explore the Patagonia Andean Forest and stop at the Curva de Los Suspiros known for its breathtaking views. Take the bus to Puerto Natales, a charming town with beautiful views of the southernmost peaks of the Andes Mountains, and the gateway to Torres del Paine National Park. Visit Torres del Paine National Park and discover Nordenskjold Lake with its emerald-green color. See the Balmaceda and Serrano Glaciers, travel to Punta Arenas and catch a flight to Santiago, a cosmopolitan city with historic attractions and modern splendors. Visit the Plaza de Armas and other famous attractions in this exhilarating city, where you will end your tour of Argentina and Chile.

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hotel

Age Range

8-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, El Calaf

Buenos Aires, Santiago, El Calafate, Puerto Natales

Duration11 days

From

USD 2,992

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Premium Chile & Argentina - October 2026

18% OFF TODAY

Super Sales

Premium Chile & Argentina - October 2026

No booking fees

Best price guaranteed

Against the magnificent backdrop of the Andes Mountains, journey from Santiago to Buenos Aires, taking in all the history, culture and cuisine in between. This nine-day Premium adventure will show you the heart of Chile and Argentina as you stroll the streets of Santiago with a local guide and sip piscos on a rooftop in the historic centre of Valparaiso. Sample some of the world’s best wine in Mendoza, stroll the stylish neighbourhoods of Buenos Aires and discover El Tigre Delta for an adventure to remember. Packed with Exclusive Experiences, historical Feature Stays and with a local leader by your side, you’ll fall for the vibrancy and indulgent atmosphere of this part of the world in no time.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Valparai

Buenos Aires, Santiago, Valparaiso, Mendoza

18% OFF TODAY

Duration9 days

From

USD 6,135

USD 5,059

Saving

USD 1,076

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Quito To Rio (114 Days) Kingdoms & Carnivals - October 2026

No booking fees

Best price guaranteed

For those of you who enjoy a challenge, join us for an overland expedition which takes you to some of the most remote places you will ever be privileged to visit. Discover the true South America with a trip that is tough but extremely rewarding! Endure bumpy rides, back to basics camping and cooking in extreme conditions whilst experiencing the beautiful landscapes and getting to know the amazing people you meet along the way. As we reach our final destination why not reward yourself by joining in with Rio's carnival spirit, in time for their legendary Carnival or New Year's Eve celebrations. Please note that the accommodation on this trip is predominantly camping, though there may be opportunities to upgrade this locally where rooms are available. Please see the trip inclusions for an approximate percentage of camping and room nights

Overland Journeys

Tour Type

Group Tour

Accommodation

Camping, Resort, Lodge

Age Range

18-80 yrs

Operated in

english

Destinations

Rio de Janeiro, Quito, Amazon Ec

Rio de Janeiro, Quito, Amazon Ecuador, El Calafate, Puerto Natales, Ushuaia, Buenos Aires, Iguazu Falls, Pantanal, Lima, Cusco, Machu Picchu, La Paz, Uyuni, Salta, Santiago

Duration114 days

From

USD 7,437

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Super Sales

Peru and Bolivia Explorer - October 2026

(1 review )

No booking fees

Best price guaranteed

The Peru and Bolivia trip was absolutely amazing! The Inca trail was a challenge but I am so glad I did it. The salt flats in Bolivia was beautiful this trip really had everything! Mountains, volcanoes, desert. Honestly the best Contiki I have been on. The included meals on the tour did not disappoint I recommend every one to do it! our trip manager was honestly the best!

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hotel, Lodge

Age Range

18-35 yrs

Operated in

english

Destinations

Santiago, Lima, Avaroa National

Santiago, Lima, Avaroa National Reserve, La Paz, Jungle Lodge, Cusco, Sacred Valley, Aguas Calientes

Duration13 days

From

USD 4,016

USD 3,896

Saving

USD 120

View Tour

All Santiago Tours in October 2026

Page 3 of 57 Trips in Santiago during October 2026 with 51 Reviews

Page 3 of 57 Trips in Santiago during October 2026 with 51 Reviews

Rio de Janeiro to Santiago Travel Pass - October 2026

Atacama & the North - 10 Days - October 2026

Grand South America - October 2026

Premium Highlights of South America - October 2026

Wonders of Patagonia - October 2026

Patagonian Explorer Cruise - October 2026

Argentina, Atacama Desert & Chile Delights - October 2026

Patagonia In Style - 14 days - October 2026

Santiago to Patagonia - 14 days - October 2026

Premium Peru, Chile & Argentina - October 2026

Essential Argentina And Chile - October 2026

Premium Chile & Argentina - October 2026

Quito To Rio (114 Days) Kingdoms & Carnivals - October 2026

Peru and Bolivia Explorer - October 2026

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Santiago Tours in October 2026

Page 3 of 57 Trips in Santiago during October 2026 with 51 Reviews

Page 3 of 57 Trips in Santiago during October 2026 with 51 Reviews