10 Best Santiago Multiday Tours in December 2025

Atacama & the North - 10 Days - December 2025

No booking fees

Best price guaranteed

Get off the beaten track in Chile’s northern reaches with this unique adventure through the Atacama Desert. Kicking off in Santiago discover fascinating museums, lunar-like landscapes of geysers and rock formations, pre-Hispanic ruins and gigantic geoglyphs, mammoth copper mines and abandoned ghost towns with plenty of natural beauty to boot.

Art and architecture

Tour Type

Private Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Santiago, Arica, San Pedro De At

Santiago, Arica, San Pedro De Atacama, Atacama Desert, El Tatio, Iquique, Putre

Duration10 days

From

USD 7,015

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Ushuaia to Santiago (Ruta 40) Travel Pass - December 2025

No booking fees

Best price guaranteed

Embark on an unforgettable Patagonian adventure from snow-capped Ushuaia to vibrant Santiago along iconic Ruta 40. Discover pristine landscapes, immersive cultural encounters, and thrilling outdoor activities. Highlights include exploring the picturesque Glacier National Park, hiking in stunning El Chaltén, and marveling at the surreal Atacama Desert. Dive into local Argentine and Chilean traditions while indulging in exceptional gastronomy. Experience the ultimate South American journey with diverse terrains, breathtaking vistas, and memorable moments tailored for adventurous travelers.

Active and outdoor

Tour Type

Group Tour

Accommodation

Hotel, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Ushuaia, Pucon, El Cal

Santiago, Ushuaia, Pucon, El Calafate, El Chalten, Perito Moreno Glacier, San Carlos de Bariloche, Puerto Varas

Duration12 days

From

USD 1,394

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Premium Highlights of South America - December 2025

No booking fees

Best price guaranteed

Experience the diversity of wonders across Peru, Chile, Argentina and Brazil on a 24-day Premium journey. Be immersed in the ancient culture of the Incas, visit the Amazon Jungle and revel in the magnificent citadel ruins of Machu Picchu. Soak up the energy of Santiago and Buenos Aires’ lively neighbourhoods and sip some of the world’s best wine in Mendoza. At the border with Brazil, experience the magnificent might of Iguazu Falls, before finally arriving in one of the most beautiful cities in the world, Rio de Janeiro. With the guidance of passionate local leaders, you’ll find out South America dances to the beat of its own drum.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Resort

Age Range

15-99 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Santiago

Rio de Janeiro, Lima, Santiago, Valparaiso, Mendoza, Buenos Aires, Puerto Maldonado, Puerto Iguazu, Amazon Lodge Tambopata, Cusco, Ollantaytambo, Machu Picchu

Duration24 days

From

USD 16,960

USD 16,451

Saving

USD 509

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19-Day Journey through South America - December 2025

Trip customizable

Best price guaranteed

This 19 days / 18 nights travel package offers you to travel the most interesting points of Patagonia, along with Brazil, in the most complete way. Departing from the city of Santiago de Chile, we will make an amazing trip through Patagonia, visiting Puerto Natales, Torres del Paine and El Calafate. Then we continue to the Argentine capital, Buenos Aires, known as the "Paris of Latin America"; The next stop will be in the Iguazú Falls, to finally reach one of Brazil biggest cities: Rio de Janeiro. Do not miss this opportunity!

GlaciersNational parks

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro

Duration19 days

From

USD 10,089

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Santiago To Rio (51 Days) - December 2025

No booking fees

Best price guaranteed

Tick some action-packed adventures off your bucket list with this once in a lifetime South American overland tour from Santiago to Rio. Begin your journey with a taste of the wonders of Patagonia. Hike to the very top of a volcano in Pucon, tackle vertical ice and trek glaciers in El Chalten and brave the rapids at Futaleufu. Take in more of the stunning sights with a closeup encounter of the Perito Moreno Glacier near El Calafate, challenge yourself to the famous 'W' Trek at Torres del Paine and explore the world's most southern city, Ushuaia in Tierra del Fuego. Continue your trip with a spot of nature watching at Valdes Peninsula, a taste of Argentina's famous steak and red wine at Buenos Aires and revel in the sights and sound of the Iguazu Falls. End your South America tour in Rio for either Carnival or New Year's Eve celebrations! Please note that the accommodation on this trip is predominantly camping, though there may be opportunities to upgrade this locally where rooms are available. Please see the trip inclusions for an approximate percentage of camping and room nights. Note: From Dec 2025 the route will be extended slightly to 58 days and will include time travelling through both Uruguay and Paraguay on the set itinerary

Overland Journeys

Tour Type

Group Tour

Accommodation

Camping, Resort

Age Range

12-85 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro, El Ch

Santiago, Rio de Janeiro, El Chaltén, Torres del Paine National Park, Buenos Aires, Montevideo, Esteros Del Ibera, Pantanal

Duration58 days

From

USD 4,552

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Santiago to Buenos Aires (via Mendoza) Travel Pass - December 2025

No booking fees

Best price guaranteed

Discover an unforgettable adventure from Santiago to Buenos Aires, immersing yourself in the rich culture and breathtaking landscapes of South America. Journey through the scenic Andes, savor exquisite wines in Mendoza, and experience vibrant city life in Buenos Aires. This curated travel pass offers guided tours, diverse outdoor activities, and authentic local experiences. Perfect for wine enthusiasts and adventure seekers, this tour offers the ultimate blend of nature, culture, and culinary delights. Book now for an extraordinary South American escapade!

Adventure

Tour Type

Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Mendoza

Buenos Aires, Santiago, Mendoza, Córdoba

Duration7 days

From

USD 505

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Patagonia In Style - 14 days - December 2025

No booking fees

Best price guaranteed

Travel in style from Santiago to the southernmost reaches of Chile and Argentina and up to Buenos Aires, staying in superior hotels and taking in Patagonia's striking landscape of towering snow-capped mountains, glacial lakes and fjords and boat ride at beneath the glaciers.

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hotel, Lodge

Age Range

18-80 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Ushuaia

Buenos Aires, Santiago, Ushuaia, Tierra Del Fuego National Park, Valparaiso, Punta Arenas, Torres Del Paine, Glacier Grey, El Calafate, Perito Moreno Glacier, Santiago

Duration14 days

From

USD 8,275

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Santiago to Patagonia - 14 days - December 2025

No booking fees

Best price guaranteed

Discover Chile in all its glorious natural beauty from the glittering lakes of Puerto Varas, the scenic archipelago of Chiloé, the panoramic views from Punta Arenas and the jagged granite peaks of the Paine massif. Along the way visit traditional fishing villages, observe comical penguins and explore Torres del Paine national park in your way.

Sightseeing ToursWaterfalls

Tour Type

Private Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Santiago, Punta Arenas, Torres D

Santiago, Punta Arenas, Torres Del Paine, Puerto Varas, Peulla, Chiloe National Park, Santiago

Duration14 days

From

USD 8,575

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La Paz to Santiago Travel Pass - December 2025

No booking fees

Best price guaranteed

Discover an unforgettable adventure from La Paz to Santiago, exploring the heart of South America with unparalleled experiences. Traverse Bolivia, Peru, and Chile, diving into the vibrant cultures of each destination. This travel pass immerses you in unique activities like gazing at the Uyuni Salt Flats, exploring the Atacama Desert, and vibrant city vibes. Perfect for backpackers and culture enthusiasts seeking an authentic journey, this tour promises unforgettable memories and breathtaking landscapes. Book now for an epic South American odyssey!

Active and outdoorVolcanoes

Tour Type

Group Tour

Accommodation

Hotel, Hostel, Lodge, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, La Paz, San Pedro De A

Santiago, La Paz, San Pedro De Atacama, La Serena, Valparaiso, Sucre, Potosi, Uyuni, Agencha, Polques

Duration17 days

From

USD 1,257

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Lima to Buenos Aires (via Chile) Travel Pass - December 2025

No booking fees

Best price guaranteed

Embark on a captivating South American adventure traversing the vibrant landscapes of Lima, Santiago, and Buenos Aires. This immersive journey takes you through Peru, Chile, and Argentina, offering unique experiences such as exploring the Sacred Valley, witnessing the surreal beauty of the Atacama Desert, and savoring world-renowned Chilean wines. Discover the rich cultural heritage of each city, from Lima's historic center to Buenos Aires' tango-filled streets. Ideal for adventurers and culture enthusiasts seeking an unforgettable travel experience.

City sightseeingLocal culture

Tour Type

Group Tour

Accommodation

Hostel, Hut, Home-stay, Bungalow, Hotel, Lodge, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Lima, Arequipa, Cu

Buenos Aires, Lima, Arequipa, Cusco, Luquina, Puno, Copacabana, Paracas, La Paz, Sucre, Potosi, Uyuni, Candelaria, Polques, San Pedro De Atacama, Calama, Valparaiso, Santiago, Mendoza, Córdoba, Huacachina, Colca Canyon

Duration41 days

From

USD 2,771

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Super Sales

Premium Peru, Chile & Argentina - December 2025

No booking fees

Best price guaranteed

Capture the true essence of South America on an 18-day Premium adventure through Peru, Chile and Argentina. This journey showcases the continent’s diversity of natural beauty, historic wonder and world-class cuisine, passing by the Andes and the Amazon, Mendoza and the majestic Machu Picchu, the Sacred Valley and sultry Santiago, all the way to the Argentinian powerhouse of Buenos Aires. Gain an insight into ancient Inca culture and local communities, indulge in fine food and some of the region’s best wine, and get to the heart of each destination with expert local knowledge at every step.

Natural landmarks sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge, Resort

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Lima, Santiago, Va

Buenos Aires, Lima, Santiago, Valparaiso, Mendoza, Amazon Jungle, Cusco, Ollantaytambo, Machu Picchu

Duration18 days

From

USD 11,170

USD 10,835

Saving

USD 335

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Essential Argentina And Chile - December 2025

Trip customizable

Best price guaranteed

Discover breathtaking natural wonders and famous cities with this small group tour of Argentina and Chile! Begin your journey in Buenos Aires, the capital of Argentina, to explore the bustling neighborhoods of the city and learn about the local history. Visit La Boca and walk around San Telmo, two of the most famous districts in Buenos Aires. Catch a flight to El Calafate as you cross the border into Chile and discover the Perito Moreno Glacier, one of the largest glaciers in the world. Explore the Patagonia Andean Forest and stop at the Curva de Los Suspiros known for its breathtaking views. Take the bus to Puerto Natales, a charming town with beautiful views of the southernmost peaks of the Andes Mountains, and the gateway to Torres del Paine National Park. Visit Torres del Paine National Park and discover Nordenskjold Lake with its emerald-green color. See the Balmaceda and Serrano Glaciers, travel to Punta Arenas and catch a flight to Santiago, a cosmopolitan city with historic attractions and modern splendors. Visit the Plaza de Armas and other famous attractions in this exhilarating city, where you will end your tour of Argentina and Chile.

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hotel

Age Range

8-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, El Calaf

Buenos Aires, Santiago, El Calafate, Puerto Natales

Duration11 days

From

USD 2,992

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Premium Chile & Argentina - December 2025

22% OFF TODAY

Super Sales

Premium Chile & Argentina - December 2025

No booking fees

Best price guaranteed

Against the magnificent backdrop of the Andes Mountains, journey from Santiago to Buenos Aires, taking in all the history, culture and cuisine in between. This nine-day Premium adventure will show you the heart of Chile and Argentina as you stroll the streets of Santiago with a local guide and sip piscos on a rooftop in the historic centre of Valparaiso. Sample some of the world’s best wine in Mendoza, stroll the stylish neighbourhoods of Buenos Aires and discover El Tigre Delta for an adventure to remember. Packed with Exclusive Experiences, historical Feature Stays and with a local leader by your side, you’ll fall for the vibrancy and indulgent atmosphere of this part of the world in no time.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Valparai

Buenos Aires, Santiago, Valparaiso, Mendoza

22% OFF TODAY

Duration9 days

From

USD 6,145

USD 4,769

Saving

USD 1,376

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Hop On Hop Off City tour Santiago, 1 Day Plus Edition - December 2025

Trip customizable

Best price guaranteed

Discover Santiago at your own pace with our Hop On Hop Off tour! Explore the city's main attractions, its vibrant neighborhoods and historical monuments. Enjoy the flexibility to hop on and off at any of the 10 designated stops, including Cerro San Cristóbal, Plaza de Armas and Bellavista. With informative audio guides and comfortable buses, this tour offers a convenient and enriching way to experience the best of Santiago

City sightseeing

Tour Type

Small Group Tour

Age Range

1-99 yrs

Operated in

english

Destinations

Santiago

Duration1 day

From

USD 73

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All Santiago Tours in December 2025

Page 3 of 53 Trips in Santiago during December 2025 with 42 Reviews

Atacama & the North - 10 Days - December 2025

Ushuaia to Santiago (Ruta 40) Travel Pass - December 2025

Premium Highlights of South America - December 2025

19-Day Journey through South America - December 2025

Santiago To Rio (51 Days) - December 2025

Santiago to Buenos Aires (via Mendoza) Travel Pass - December 2025

Patagonia In Style - 14 days - December 2025

Santiago to Patagonia - 14 days - December 2025

La Paz to Santiago Travel Pass - December 2025

Lima to Buenos Aires (via Chile) Travel Pass - December 2025

Premium Peru, Chile & Argentina - December 2025

Essential Argentina And Chile - December 2025

Premium Chile & Argentina - December 2025

Hop On Hop Off City tour Santiago, 1 Day Plus Edition - December 2025

Page 3 of 53 Trips in Santiago during December 2025 with 42 Reviews

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Santiago Tours in December 2025

Page 3 of 53 Trips in Santiago during December 2025 with 42 Reviews

Page 3 of 53 Trips in Santiago during December 2025 with 42 Reviews