10 Best Panama City Multiday Tours in Fall

Get a customized trip to Panama City in Fall

Plan a multi-country or regional adventure across Panama City in Fall, with help from a local expert.

Olman RomeroTravel Expert in Costa Rica, Nicaragua & Panama
Yuliana ValverdeTravel Expert in Costa Rica, Nicaragua & Panama

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Wonders of Central America - 22 days - Fall tours

No booking fees

Best price guaranteed

Discover the natural and cultural highlights of six Central American countries on this three-week tour which travels from Panama to Guatemala. Visit wildlife-rich national parks and remote islands, uncover ancient secrets in Mayan ruins and roam around colonial cities.

City sightseeing

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Panama City, Antigua, Granada, L

Panama City, Antigua, Granada, Leon, La Union, Boquete, Cahuita National Park, Monteverde, Ometepe Island

Duration22 days

From

USD 5,845

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Panama City to Mexico City Travel Pass - Fall tours

No booking fees

Best price guaranteed

Embark on a vibrant journey from Panama City to Mexico City with Bamba Travel, exploring stunning landscapes, rich cultures, and iconic landmarks. Delight in unique experiences such as traversing the Panama Canal, wandering through colonial Cartagena, adventuring in Costa Rica’s lush rainforests, and diving into the vibrant markets of Oaxaca. Savor authentic Latin American cuisine, immerse in local traditions, and enjoy seamless travel connections. Perfect for thrill-seekers and culture enthusiasts, this adventure promises unforgettable memories.

Local culture

Tour Type

Group Tour

Accommodation

Home-stay, Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Mexico City, Panama City, San Bl

Mexico City, Panama City, San Blas Islands, San Jose, Manuel Antonio, Monteverde, Liberia City, San Juan Del Sur, San Jorge, Ometepe, Granada, Leon, El Tunco, Copán Ruinas, Antigua, Panajachel, San Jorge La Laguna, San Cristobal De Las Casas, Pochutla, Puerto Escondido, Bocas Del Toro, Oaxaca, Puerto Viejo de Talamanca, Tortuguero

Duration42 days

From

USD 4,019

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Self-Drive: Panama Adventure & Beach Explorer 15D/14N - Fall tours

No booking fees

Best price guaranteed

Embark on an unforgettable Panama adventure with this exhilarating self-drive tour. Explore lush rainforests, stunning beaches, and vibrant local culture. Highlights include wildlife spotting in Soberania National Park, relaxation on the pristine shores of Bocas del Toro, and thrilling zip-lining in Boquete. Discover the wonders of historic Panama City and the engineering marvel of the Panama Canal. Perfect for independent travelers seeking outdoor thrills and serene beach escapades. Experience the ultimate Panama vacation with adventure and relaxation in one package.

AdventureBicycle tours

Tour Type

Private Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City, Boquete, Las Lajas

Panama City, Boquete, Las Lajas, El Valle, Pedasí

Duration15 days

From

USD 1,900

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Panama: Craters, Coasts & Highland Mountains - Fall Tours

10% OFF TODAY

Super Sales

Panama: Craters, Coasts & Highland Mountains - Fall tours

No booking fees

Best price guaranteed

Eighteen days of next-level beaches, wild landscapes, and full-on freedom — this is Panama like you’ve never seen it. Start in Costa Rica and cruise into the often-overlooked magic of Panama, where every stop hits different. Catch the surfy vibes in Puerto Viejo, snorkel your heart out in Bocas del Toro, and hike cloud forest trails in lush Boquete. Sleep inside a volcanic crater in the town of Valle de Antón, dance the night away in Panama City, and unplug completely with three off-the-grid nights on the jaw-dropping San Blas Islands. Between waterfalls, reefs, Indigenous culture, and epic new friendships, this trip brings the kind of stories you’ll be telling for years.

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Hostel, Hotel, Hut

Age Range

18-39 yrs

Operated in

english

Destinations

Panama City, San Jose, Valle De

Panama City, San Jose, Valle De Antón, San Blas Islands, Puerto Viejo de Talamanca, Bocas Del Toro, Boquete

10% OFF TODAY

Duration18 days

From

USD 2,049

USD 1,844

Saving

USD 205

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Welcome to Panama City 3D/2N - Fall tours

No booking fees

Best price guaranteed

Embark on a captivating journey through Panama City, uniting the thrilling energy of the local culture with the historic charm of Casco Viejo. From the moment you arrive, immerse yourself in the tales of ancient streets, the beauty of striking architecture, and the stories of the past that shape today. This three-day jaunt promises a delightful blend of exploration, discovery, and leisure, enveloped within breathtaking sights and vibrant histories.

ExplorerBicycle tours

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City

Duration3 days

From

USD 213

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Discover the Unseen Panama 13D/12N - Fall tours

No booking fees

Best price guaranteed

Discover the mesmerizing fusion of vibrant city life and tranquil coastal paradises in Panama. Journey through historical sites, breathtaking beaches, and rich biodiversity, while uncovering the diverse cultural tapestry of this captivating nation. From Panama City's urban allure to Bocas del Toro's eco-escapades, every day offers a unique adventure amidst stunning landscapes and vibrant culture.

Explorer

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City, Bocas Del Toro, Pla

Panama City, Bocas Del Toro, Playa Venao, Santa Catalina, Boquete

Duration13 days

From

USD 2,038

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Welcome to Panama City 4D/3N - Fall tours

No booking fees

Best price guaranteed

Uncover the mystique of Panama City over four captivating days, where vibrant cultures intertwine with the timeless remnants of Casco Viejo. Traverse the enchanting streets and immerse yourself in the living history, intriguing architecture, and bustling local life that define this dynamic region. Each day unveils a new chapter of exploration, inviting you into the heart of Panama's most storied locales.

ExplorerBicycle tours

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City

Duration4 days

From

USD 302

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Costa Rica To Panama: Surf, Treks & Starry Skies - Fall Tours

10% OFF TODAY

Super Sales

Costa Rica to Panama: Surf, Treks & Starry Skies - Fall tours

No booking fees

Best price guaranteed

Ready to bounce from beach to jungle to crater town? This 13-day trip kicks off in Costa Rica and cruises into the wild beauty of Panama, where laid-back vibes meet epic adventure. Chill out on the Caribbean coast in Puerto Viejo, snorkel through starfish-studded waters in Bocas del Toro, and hike cloud forest trails to hidden waterfalls in Boquete. You’ll get up close with local culture, learn how chocolate is made from the source, and hang out in Valle de Antón — an actual town inside a volcanic crater. Wrap it up with a night out in Panama City, and you’ve got a Central American escape that’s anything but basic.

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Hostel, Hotel

Age Range

18-39 yrs

Operated in

english

Destinations

Panama City, San Jose, Valle De

Panama City, San Jose, Valle De Antón, Puerto Viejo de Talamanca, Bocas Del Toro, Boquete

10% OFF TODAY

Duration13 days

From

USD 1,199

USD 1,079

Saving

USD 120

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Panama: Sandy Beaches & San Blas Sunsets - Fall Tours

10% OFF TODAY

Super Sales

Panama: Sandy Beaches & San Blas Sunsets - Fall tours

No booking fees

Best price guaranteed

Looking to unplug and drop off the grid in total island style? This 6-day adventure takes you from the buzz of Panama City to the untouched paradise of the San Blas Islands — and trust us, it’s next-level. Start by soaking in the city’s mix of modern energy and historic charm, before setting sail for the Caribbean. Picture crystal-clear water, palm trees swaying over white sand, and zero Wi-Fi to distract you. The San Blas Islands are run by the Indigenous Guna people, giving you the chance to connect with local culture and traditions while living that beachside barefoot dream. No filters needed — this is as real as paradise gets.

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel, Hut

Age Range

18-39 yrs

Operated in

english

Destinations

Panama City, San Blas Islands

10% OFF TODAY

Duration6 days

From

USD 899

USD 809

Saving

USD 90

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All Panama City Tours in Fall

Page 3 of 37 Trips in Panama City with 19 Reviews

Get a customized trip to Panama City in Fall

Page 3 of 37 Trips in Panama City with 19 Reviews

Wonders of Central America - 22 days - Fall tours

Panama City to Mexico City Travel Pass - Fall tours

Self-Drive: Panama Adventure & Beach Explorer 15D/14N - Fall tours

Panama: Craters, Coasts & Highland Mountains - Fall tours

Welcome to Panama City 3D/2N - Fall tours

Discover the Unseen Panama 13D/12N - Fall tours

Welcome to Panama City 4D/3N - Fall tours

Costa Rica to Panama: Surf, Treks & Starry Skies - Fall tours

Panama: Sandy Beaches & San Blas Sunsets - Fall tours

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Panama City Tours in Fall

Page 3 of 37 Trips in Panama City with 19 Reviews

Get a customized trip to Panama City in Fall

Page 3 of 37 Trips in Panama City with 19 Reviews