10 Best Panama City Multiday Tours in Fall

San Blas Chichime Islands Experience 4D/3N - Fall tours

No booking fees

Best price guaranteed

Escape to a tropical paradise with an unforgettable adventure in the San Blas Chichime Islands. Revel in pristine beaches, crystal-clear waters, and vibrant marine life. Snorkel around coral reefs, interact with the indigenous Guna Yala community, and savor mouthwatering seafood. Enjoy the rustic charm of island cabins amidst swaying palms. Ideal for travelers seeking relaxation and exploration, this experience offers the perfect blend of cultural immersion and natural beauty. Discover why the San Blas Islands are a top bucket-list destination.

AdventureExplorer

Tour Type

Small Group Tour

Accommodation

Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City, San Blas Islands

Duration4 days

From

USD 575

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Central American Explorer - Fall tours

4.8

(13 reviews )

No booking fees

Best price guaranteed

Great trip. Fantastic leader Wonderful experience

Active and outdoorExplorer

Tour Type

Small Group Tour

Accommodation

Hotel, Eco Lodge, Lodge, Villa

Age Range

16-99 yrs

Operated in

english

Destinations

Panama City, Antigua, Rincon de

Panama City, Antigua, Rincon de la Vieja Volcano National Park, Isla De Ometepe, Granada, Leon, San Salvador, Suchitoto, Panama Canal, Copán Ruinas, Boquete, Bocas Del Toro, Sarapiqui, Arenal, Monteverde Cloud Forest Biological Preserve

Duration25 days

From

USD 6,020

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San Jose to Panama City Travel Pass - Fall tours

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Costa Rica's vibrant San Jose to Panama City's cultural heart. Experience thrilling zip-lining in Monteverde, discover Arenal's majestic volcano, soak in thermal hot springs, and relax on Bocas del Toro's pristine beaches. Journey through dense jungles, explore indigenous villages, and marvel at the striking Panama Canal. This travel pass offers a seamless blend of natural wonders, adrenaline-pumping activities, and rich cultural encounters, making it perfect for adventurous travelers seeking an immersive Central American odyssey.

Sightseeing ToursExplorer

Tour Type

Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City, San Jose, Puerto Vi

Panama City, San Jose, Puerto Viejo de Talamanca, Bocas Del Toro, San Blas Islands

Duration7 days

From

USD 877

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Panama City to San Jose Travel Pass - Fall tours

No booking fees

Best price guaranteed

Embark on an unforgettable journey from Panama City to San Jose with Bamba travel. Experience the best of Central America, exploring lush rainforests, pristine beaches, and vibrant local cultures. Highlights include island-hopping in Bocas del Toro, thrilling zip-lining in the Costa Rican canopy, and immersing yourself in indigenous traditions. Perfect for adventure seekers, this tour promises unique cultural encounters and breathtaking natural beauty, ensuring an exhilarating and diverse travel experience you won't forget. Book now for the ultimate Central American adventure!

National parks

Tour Type

Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City, San Jose, La Fortun

Panama City, San Jose, La Fortuna, San Blas Islands, Bocas Del Toro, Puerto Viejo de Talamanca

Duration10 days

From

USD 1,549

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Panama City to Bogota Travel Pass - Fall tours

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Panama City to Bogota, immersing yourself in vibrant cultures, lush landscapes, and rich histories. This seamless travel pass offers unique experiences, including exploring Panama Canal’s marvels, snorkeling in San Blas Islands’ crystal waters, discovering Medellín's urban transformation, and delving into Bogota’s dynamic arts scene. Perfect for thrill-seekers and culture enthusiasts, this tour promises a diverse blend of activities, ensuring an enriching journey through Central America's hidden gems and Colombia's enchanting urban hubs.

BeachSnorkelingExplorer

Tour Type

Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Bogota, Panama City, San Blas Is

Bogota, Panama City, San Blas Islands, Medellin, Manizales, Hacienda Venecia Coffe Farm

Duration10 days

From

USD 1,629

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Super Sales

Central and South American Adventure: From Costa Rica to Colombia - Fall tours

No booking fees

Best price guaranteed

Phones charged and playlists queued — this 27-day journey is a full-on adventure through Central and South America that’s packed with wild nature, laid-back beach towns, and buzzing cities. Start in Costa Rica with the surfy chill of Puerto Viejo before heading into Panama’s hidden gems — think island time in Bocas del Toro, misty hikes in Boquete, and the crater village of Valle de Antón. Then go fully off-grid on the San Blas Islands, where Indigenous communities run the show and turquoise water meets white sand. After that, it’s Colombia time. Wander Cartagena’s colourful old town, trek through jungle trails to waterfalls in Minca, kick back in Santa Marta, and finish strong in Medellín with mountaintop views and a nightlife scene to match. From slow travel moments to fast-paced fun, this one’s got it all.

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Hostel, Hotel, Hut

Age Range

18-39 yrs

Operated in

english

Destinations

San Jose, Medellin, Valle De Ant

San Jose, Medellin, Valle De Antón, Panama City, San Blas Islands, Cartagena, Puerto Viejo de Talamanca, Minca, Palomino, Tayrona National Park, Santa Marta, Bocas Del Toro, Boquete

Duration27 days

From

USD 3,999

USD 3,879

Saving

USD 120

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Super Sales

Panama: Craters, Coasts & Highland Mountains - Fall tours

No booking fees

Best price guaranteed

Eighteen days of next-level beaches, wild landscapes, and full-on freedom — this is Panama like you’ve never seen it. Start in Costa Rica and cruise into the often-overlooked magic of Panama, where every stop hits different. Catch the surfy vibes in Puerto Viejo, snorkel your heart out in Bocas del Toro, and hike cloud forest trails in lush Boquete. Sleep inside a volcanic crater in the town of Valle de Antón, dance the night away in Panama City, and unplug completely with three off-the-grid nights on the jaw-dropping San Blas Islands. Between waterfalls, reefs, Indigenous culture, and epic new friendships, this trip brings the kind of stories you’ll be telling for years.

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Hostel, Hotel, Hut

Age Range

18-39 yrs

Operated in

english

Destinations

Panama City, San Jose, Valle De

Panama City, San Jose, Valle De Antón, San Blas Islands, Puerto Viejo de Talamanca, Bocas Del Toro, Boquete

Duration18 days

From

USD 2,049

USD 1,988

Saving

USD 61

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Super Sales

Costa Rica to Panama: Surf, Treks & Starry Skies - Fall tours

No booking fees

Best price guaranteed

Ready to bounce from beach to jungle to crater town? This 13-day trip kicks off in Costa Rica and cruises into the wild beauty of Panama, where laid-back vibes meet epic adventure. Chill out on the Caribbean coast in Puerto Viejo, snorkel through starfish-studded waters in Bocas del Toro, and hike cloud forest trails to hidden waterfalls in Boquete. You’ll get up close with local culture, learn how chocolate is made from the source, and hang out in Valle de Antón — an actual town inside a volcanic crater. Wrap it up with a night out in Panama City, and you’ve got a Central American escape that’s anything but basic.

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Hostel, Hotel

Age Range

18-39 yrs

Operated in

english

Destinations

Panama City, San Jose, Valle De

Panama City, San Jose, Valle De Antón, Puerto Viejo de Talamanca, Bocas Del Toro, Boquete

Duration13 days

From

USD 1,199

USD 1,163

Saving

USD 36

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Super Sales

Panama: Sandy Beaches & San Blas Sunsets - Fall tours

No booking fees

Best price guaranteed

Looking to unplug and drop off the grid in total island style? This 6-day adventure takes you from the buzz of Panama City to the untouched paradise of the San Blas Islands — and trust us, it’s next-level. Start by soaking in the city’s mix of modern energy and historic charm, before setting sail for the Caribbean. Picture crystal-clear water, palm trees swaying over white sand, and zero Wi-Fi to distract you. The San Blas Islands are run by the Indigenous Guna people, giving you the chance to connect with local culture and traditions while living that beachside barefoot dream. No filters needed — this is as real as paradise gets.

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel, Hut

Age Range

18-39 yrs

Operated in

english

Destinations

Panama City, San Blas Islands

Duration6 days

From

USD 899

USD 872

Saving

USD 27

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Super Sales

Total Central America: Two Months of Wild - Fall tours

No booking fees

Best price guaranteed

Two months. Seven countries. One unforgettable ride. This all-out Central American adventure kicks off in Mexico City with tacos, mole, and big energy — then it’s full speed ahead through mountains, jungles, highlands, beaches, and islands. You’ll snorkel in Belize, boat across Lake Atitlán, crash with a local fam on Nicaragua’s Ometepe Island, and dance the night away in Panama City. Whether you’re soaking in cloud forest vibes in Costa Rica or chilling barefoot on the San Blas Islands, this trip is the ultimate way to see it all. From street eats to off-the-grid retreats, it’s two months of pure adventure — and it’s calling your name.

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Home-stay, Hostel, Hotel, Hut

Age Range

18-39 yrs

Operated in

english

Destinations

Mexico City, Panama City, Bacala

Mexico City, Panama City, Bacalar, Valladolid, Tulum, Playa Del Carmen, Caye Caulker, San Ignacio, Flores, Rio Dulce, Antigua, Panajachel, San Juan La Laguna, Oaxaca, Copan, Suchitoto, La Libertad, Leon, Granada, Isla De Ometepe, Monteverde, La Fortuna, San Jose, Puerto Viejo de Talamanca, Bocas Del Toro, San Cristobal De Las Casas, Boquete, Valle De Antón, San Blas Islands, Palenque

Duration62 days

From

USD 6,199

USD 6,013

Saving

USD 186

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Welcome to Panama City 4D/3N - Fall tours

No booking fees

Best price guaranteed

Uncover the mystique of Panama City over four captivating days, where vibrant cultures intertwine with the timeless remnants of Casco Viejo. Traverse the enchanting streets and immerse yourself in the living history, intriguing architecture, and bustling local life that define this dynamic region. Each day unveils a new chapter of exploration, inviting you into the heart of Panama's most storied locales.

Explorer

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City

Duration4 days

From

USD 302

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Welcome to Panama City 3D/2N - Fall tours

No booking fees

Best price guaranteed

Embark on a captivating journey through Panama City, uniting the thrilling energy of the local culture with the historic charm of Casco Viejo. From the moment you arrive, immerse yourself in the tales of ancient streets, the beauty of striking architecture, and the stories of the past that shape today. This three-day jaunt promises a delightful blend of exploration, discovery, and leisure, enveloped within breathtaking sights and vibrant histories.

Explorer

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City

Duration3 days

From

USD 213

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Discover the Unseen Panama 13D/12N - Fall tours

No booking fees

Best price guaranteed

Discover the mesmerizing fusion of vibrant city life and tranquil coastal paradises in Panama. Journey through historical sites, breathtaking beaches, and rich biodiversity, while uncovering the diverse cultural tapestry of this captivating nation. From Panama City's urban allure to Bocas del Toro's eco-escapades, every day offers a unique adventure amidst stunning landscapes and vibrant culture.

Explorer

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City, Bocas Del Toro, Pla

Panama City, Bocas Del Toro, Playa Venao, Santa Catalina, Boquete

Duration13 days

From

USD 2,038

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Antigua to Panama City Travel Pass - Fall tours

No booking fees

Best price guaranteed

Embark on an unforgettable Central America adventure with Bamba’s travel pass taking you from Antigua to Panama City. This immersive journey offers diverse experiences including exploring ancient Mayan ruins, soaking up the sun on pristine beaches, and hiking lush rainforests. Thrill-seekers can revel in adrenaline-pumping activities like volcano treks and zip-lining. Discover vibrant cultures, delicious cuisine, and captivating landscapes. Ideal for solo travelers and groups alike, this adventure ensures a seamless and memorable travel experience across stunning destinations.

Explorer

Tour Type

Group Tour

Accommodation

Home-stay, Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Panama City, Antigua, Panajachel

Panama City, Antigua, Panajachel, El Tunco, Leon, Granada, San Jorge, Ometepe, San Juan Del Sur, Liberia City, San Jorge La Laguna, Monteverde, Manuel Antonio, San Jose, Tortuguero, Puerto Viejo de Talamanca, Bocas Del Toro, San Blas Islands, Lanquin, Copán Ruinas

Duration35 days

From

USD 3,471

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All Panama City Tours in Fall

15 Trips in Panama City with 13 Reviews

San Blas Chichime Islands Experience 4D/3N - Fall tours

Central American Explorer - Fall tours

San Jose to Panama City Travel Pass - Fall tours

Panama City to San Jose Travel Pass - Fall tours

Panama City to Bogota Travel Pass - Fall tours

Central and South American Adventure: From Costa Rica to Colombia - Fall tours

Panama: Craters, Coasts & Highland Mountains - Fall tours

Costa Rica to Panama: Surf, Treks & Starry Skies - Fall tours

Panama: Sandy Beaches & San Blas Sunsets - Fall tours

Total Central America: Two Months of Wild - Fall tours

Welcome to Panama City 4D/3N - Fall tours

Welcome to Panama City 3D/2N - Fall tours

Discover the Unseen Panama 13D/12N - Fall tours

Antigua to Panama City Travel Pass - Fall tours

15 Trips in Panama City with 13 Reviews

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All Panama City Tours in Fall

15 Trips in Panama City with 13 Reviews

15 Trips in Panama City with 13 Reviews