10 Best Panama City Multiday Tours in December 2026

Accommodations

BudgetSimple stays with essential amenities. Typically guesthouses, hostels or hotels rated below 3 stars — clean, no-frills, and great for value-conscious travelers.
Mid-rangeComfortable and reliable 3-star stays. Expect private rooms, en-suite bathrooms, and solid amenities — a great balance between comfort and cost.
PremiumUpscale 4-5 star hotels and lodges. Enjoy high-end service, refined comfort, and premium locations — ideal for travelers seeking extra indulgence.

Get a customized trip to Panama City in December 2026

Plan a multi-country or regional adventure across Panama City in December 2026, with help from a local expert.

Olman RomeroTravel Expert in Costa Rica, Nicaragua & Panama
Yuliana ValverdeTravel Expert in Costa Rica, Nicaragua & Panama

Start planning your Trip

Recommended by

5 Trips in Panama City during December 2026

Costa Rica & Panama Discovery - December 2026

18% OFF TODAY

Halloween Super Sales

Costa Rica & Panama Discovery - December 2026

(1 review )

No booking fees

Best price guaranteed

Get under the surface of Costa Rica and Panama with this 12-day Caribbean adventure. From San Jose to Panama City, you’ll get introduced to some of the most beautiful spots in two Central American countries, with a perfect balance of included activities and free time for your own explorations. You’ll visit the Ngabe-Bugle community on Isla Popa, learn how to make a traditional Caribbean meal, look out for wildlife on a jungle walk, visit a lock along the Panama Canal and soak in the local hotspots in areas seldom travelled. You can't go wrong with your local leader to steer you in the right direction (to the best bars and surf breaks), plus a small group of adventurers to enjoy them with.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Panama City, San Jose, Puerto Vi

Panama City, San Jose, Puerto Viejo de Talamanca, Chitre, Isla Colon, Bocas Del Toro, Boquete

18% OFF TODAY

Duration12 days

From

USD 2,110

USD 1,740

Saving

USD 370

View Tour

13% OFF TODAY

Halloween Super Sales

Best of Central America - December 2026

No booking fees

Best price guaranteed

Explore incredible worlds above and below the water through some of Central America's best on this 45-day adventure. Amble down the Yucatan Peninsula to the island paradise of Caye Caulker, then cut inland to the lush jungle around Tikal, cruise to the wide river Rio Dulce and end up among the clouds in Panajachel and Antigua. Continue to the relaxing beach vibes of the Pacific Coast of El Salvador, spot colourful birds perched on the historic facades of Suchitoto and explore the historic cities of Leon and Granada in Nicaragua. Stand in the shadow of mighty Arenal Volcano and spot sloths among the canopy of Monteverde, then admire the towns and steamy jungles of Costa Rice and Panama, stopping off at the stunning islands of Bocas del Toro. With plenty of moments to meet the locals and try the region’s varied cuisines, you can’t go wrong on this carefree Central American journey.

WildlifeCity sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel, Hut, Lodge

Age Range

15-99 yrs

Operated in

english

Destinations

Panama City, Playa Del Carmen, R

Panama City, Playa Del Carmen, Rio Dulce, Antigua, Quetzaltenango, Panajachel, Tulum, Copan, Suchitoto, La Libertad, Leon, Granada, Monteverde, La Fortuna, San Jose, Sarapiqui, Puerto Viejo de Talamanca, Bocas Del Toro, Caye Caulker, Boquete, Chitre, San Ignacio, Flores

13% OFF TODAY

Duration45 days

Halloween Super Sales

Amazing Central America - December 2026

No booking fees

Best price guaranteed

Get ready for a 27-day adventure through Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica and Panama. From oceans teeming with marine life to tropical forests alive with jungle melodies, this pocket of Central America is truly a natural paradise. You’ll explore the intricately carved structures at Copan, the cloud forests of Monteverde and spend three nights in the island paradise of Bocas del Toro. Sample varied cuisines along the way during cooking lessons with locals, giving you a real insight into the heart and soul of Central America.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Hut

Age Range

15-99 yrs

Operated in

english

Destinations

Panama City, San Jose, Antigua

Panama City, San Jose, Antigua, Monteverde Cloud Forest Biological Preserve, Puerto Viejo de Talamanca, Cahuita National Park, Granada, Monteverde, La Fortuna, Sarapiqui, Copan, Bocas Del Toro, Boquete, Chitre, Suchitoto, El Cuco, Leon

Duration27 days

13% OFF TODAY

Halloween Super Sales

Ultimate Central America - December 2026

No booking fees

Best price guaranteed

Embark on an in-depth, 59-day Central American adventure from Mexico’s capital to the home of the Panama Canal. Pass through Mexico, Belize, Guatemala, El Salvador, Honduras, Nicaragua, Costa Rica and Panama on a small-group journey through remote villages, historic cities, ancient Maya and Aztec ruins, verdant cloud forests and pure Caribbean beaches. Get acquainted with the local cultures, spectacular landscapes and fascinating histories of Central America as you explore the wealth of tradition, spot the range of unusual wildlife, dive into unique underwater worlds and spend time travelling with like-minded people. Did you hear that? Central America is calling – you better Belize it.

City sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel, Hut, Lodge

Age Range

15-99 yrs

Operated in

english

Destinations

Mexico City, Panama City, Palenq

Mexico City, Panama City, Palenque, Merida, Playa Del Carmen, Chetumal, Caye Caulker, San Ignacio, Flores, Rio Dulce, Antigua, Quetzaltenango, Puebla, Panajachel, Copan, Suchitoto, La Libertad, Leon, Granada, Monteverde, La Fortuna, San Jose, Sarapiqui, Oaxaca, Puerto Viejo de Talamanca, Bocas Del Toro, Boquete, Chitre, San Cristobal De Las Casas

13% OFF TODAY

Duration59 days

Halloween Super Sales

Wonders of Central America - 22 days - December 2026

No booking fees

Best price guaranteed

Discover the natural and cultural highlights of six Central American countries on this three-week tour which travels from Panama to Guatemala. Visit wildlife-rich national parks and remote islands, uncover ancient secrets in Mayan ruins and roam around colonial cities.

City sightseeing

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Panama City, Antigua, Granada, L

Panama City, Antigua, Granada, Leon, Boquete, Cahuita National Park, Monteverde, Ometepe Island

Duration22 days

From

USD 7,390

USD 6,451

Saving

USD 939

From

USD 4,030

USD 3,909

Saving

USD 121

From

USD 10,390

USD 9,070

Saving

USD 1,320

From

USD 5,935

USD 5,757

Saving

USD 178

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Panama City Tours in December 2026

5 Trips in Panama City during December 2026

Get a customized trip to Panama City in December 2026

5 Trips in Panama City during December 2026

Costa Rica & Panama Discovery - December 2026

Best of Central America - December 2026

Amazing Central America - December 2026

Ultimate Central America - December 2026

Wonders of Central America - 22 days - December 2026