Simple stays with essential amenities. Typically guesthouses, hostels or hotels rated below 3 stars — clean, no-frills, and great for value-conscious travelers.
Comfortable and reliable 3-star stays. Expect private rooms, en-suite bathrooms, and solid amenities — a great balance between comfort and cost.
Upscale 4-5 star hotels and lodges. Enjoy high-end service, refined comfort, and premium locations — ideal for travelers seeking extra indulgence.
Guide Types
Activities
Price
USD 1,124USD 15,278
Start & End Location
Page 3 of 41 Trips in Isla Santa Cruz during September 2025 with 54 Reviews
Set off on an extraordinary journey across three of South America’s most captivating countries — Ecuador, Peru, and Colombia — with this carefully curated small-group tour that blends exotic wildlife, ancient wonders, vibrant culture, and breathtaking landscapes. Begin your adventure in Quito, Ecuador’s colonial capital nestled in the Andes, before heading to the legendary Galápagos Islands, a once-in-a-lifetime destination. Cruise between Santa Cruz and Isabela Islands, home to Giant Tortoises, Blue-Footed Boobies, marine iguanas, and the surreal Tintoreras Islets. Snorkel with sea lions, visit volcanic landscapes, and relax by the pink-hued Flamingo Lagoon. Enjoy seamless logistics and expert guides as you explore one of the world’s most biologically diverse regions. Next, fly to Lima, Peru’s capital, before soaring over the Andes to the ancient heart of the Inca Empire — Cusco. Discover Incan marvels, including the imposing Sacsayhuamán Fortress, and board a panoramic train through the Sacred Valley to reach the mystical Machu Picchu, a UNESCO World Heritage Site and one of the New Seven Wonders of the World. Continue to Colombia, where you’ll be enchanted by the blend of history, nature, and coffee culture. Explore Bogotá, take in panoramic views from Monserrate Hill, and dive deep into the Coffee Triangle, where lush plantations and rich aromas await. End your tour in Cartagena, a UNESCO-listed Caribbean gem, with its cobblestone streets, colonial fortresses, and vibrant culture — a magical finale by the sea.
Cultural, religious and historic sites
Tour Type
Group Tour
Accommodation
Hotel, Lodge
Age Range
8-99 yrs
Operated in
english
Destinations
Quito, Cartagena, Sacred Valley
Quito, Cartagena, Sacred Valley, Armenia, Cusco, Lima, Bogota, Isla Santa Cruz, Isabela Island, Urubamba
Visit South America and travel to the Galapagos Islands, Peru, Ecuador, and Bolivia. Amazing wildlife, both on land and underwater, is the drawcard of the remote Galapagos Islands. Discover unique creatures, as well as the island's outstanding natural beauty, by foot, boat and bike. Back on the mainland, enjoy the delights of Peru – from the tough but rewarding Inca Trail to the joy of interacting with friendly locals and experiencing cities full of colour, energy and passion.
Cultural, religious and historic sites
Tour Type
Small Group TourSmall group tours usually have 8-12 participants and maximum up to 18 travelers
Accommodation
Hotel, Camping, Lodge, Eco Lodge, Home-stay
Age Range
15-99 yrs
Operated in
english
Destinations
Quito, La Paz, Lima, Puerto Mald
Quito, La Paz, Lima, Puerto Maldonado, Amazon Lodge Tambopata, Cusco, Ollantaytambo, Inca Trail, San Cristobal Island, Puno, Isla Isabela, Isla Santa Cruz
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Uncover the magic of two of South America's most breathtaking destinations on this extraordinary small-group journey through Ecuador and Peru. From ancient cities steeped in history to otherworldly landscapes and awe-inspiring world wonders, this adventure is filled with unforgettable moments. Begin in Quito, Ecuador’s charming capital nestled in the Andes, before flying to Baltra Island, the gateway to the legendary Galápagos Islands. Cross into Santa Cruz Island, where you'll walk among giant tortoises in their natural habitat, explore lush highlands, and marvel at dramatic volcanic landscapes. Cruise the turquoise waters around Puerto Ayora, snorkeling at La Lobería with playful sea lions, graceful sea turtles, and vibrant tropical fish. Continue your exploration with visits to North Seymour and Bachas Islands, teeming with seabirds, iguanas, and untouched beaches. Next, fly to Lima, Peru's dynamic capital, where colonial grandeur meets contemporary culture in neighborhoods like Miraflores, San Isidro, and the coastal Parque del Amor. Soar over the Andes to Cusco, the historic heart of the Inca Empire. Wind through the Sacred Valley, where ancient agricultural terraces and Andean villages line the route to Machu Picchu — the mystical Lost City of the Incas, perched high among misty peaks. Back in Cusco, walk in the footsteps of emperors at the Temple of the Sun and the mighty Sacsayhuaman Fortress, where immense stones speak of a glorious past. From the pristine Galápagos Islands to the timeless ruins of the Andes, this journey blends nature, history, and culture into an experience that will linger in your memory forever.
This is a Solo Tour
You don't pay a single supplement and get a room for yourself!
Cultural, religious and historic sites
Tour Type
Small Group TourSmall group tours usually have 8-12 participants and maximum up to 18 travelers
Accommodation
Hotel
Age Range
8-99 yrs
Operated in
english
Destinations
Cusco, Galapagos Islands, Guayaq
Cusco, Galapagos Islands, Guayaquil, Sacred Valley, Isla Santa Cruz, Puerto Ayora, Lima
This 10-day adventure begins in Quito, Ecuador, a UNESCO World Heritage Site known for its vibrant culture and well-preserved colonial center.
The journey continues to the Galapagos Islands, where you'll explore the diverse wildlife and volcanic landscapes that inspired Charles Darwin's theory of evolution. On San Cristobal Island, you'll visit "La Loberia," a beach teeming with playful sea lions, marine iguanas, and various bird species. You'll then embark on a thrilling speedboat trip to Kicker Rock, a renowned snorkeling site known for its diverse marine life.
Next, you'll fly to Isabela Island, the largest and most volcanically active island in the Galapagos archipelago. Here, you'll encounter flamingos, marine iguanas, giant tortoises, and other fascinating creatures. You'll explore lava formations, snorkel with playful sea lions and penguins, and witness sea turtles navigating lava tunnels.
The adventure concludes on Santa Cruz Island, where you'll visit the Charles Darwin Research Station to learn about the unique endemic species and ongoing conservation efforts.
Finally, you'll return to Quito, where you'll have time to reflect of the memories made in the Galapagos Islands.
In the Galapagos we offer a selection of tours of varying lengths and activity levels:
7 Day - Galapagos Essentials - Our lead-in product, ideal for those looking to experience the natural beauty of the Galapagos without being too active. This tour visits the Islands of Santa Cruz and San Cristobel.
7 Day - Best of the Galapagos - For those looking for an activity based trip to the Galapagos, our Best of the Galapagos tour has a more active itinerary, including a hike on the Sierra Negra Volcano. This tour visits the Islands of Isabela and Santa Cruz.
10 Day - Galapagos Uncovered - For passengers with more time available, our Galapagos Uncovered tour is a great option, this tour includes a good mix of activities and includes visits to three islands; San Cristobel, Isabela and Santa Cruz.
Explorer
Tour Type
Small Group TourSmall group tours usually have 8-12 participants and maximum up to 18 travelers
Accommodation
Hotel
Age Range
8-95 yrs
Operated in
english
Destinations
Quito, San Cristobal Island, Isa
Quito, San Cristobal Island, Isabela Island, Las Tintoreras Islet, Isla Santa Cruz, Charles Darwin Research Centre
Set out on a Galapagos island-hopping adventure on this 7-day group tour from Quito. Kayak and snorkel alongside curious sea lions, hike to a volcanic crater and roam the Santa Cruz highlands among giant tortoises, plus so much more. Isolated for millennia, these islands offer close, awe-inspiring encounters with wildlife found nowhere else. This journey supports local communities and protects the fragile ecosystem - offering you a rare chance to explore one of the world’s most fiercely guarded marine sanctuaries.
Explorer
Tour Type
Small Group TourSmall group tours usually have 8-12 participants and maximum up to 18 travelers
Discover Ecuador and the Galapagos Islands on this 12-day family friendly adventure, taking in Quito's colonial charm, the Galapagos’ unique wildlife and stunning landscapes. Hike the Sierra Negra volcano, snorkel in crystal-clear waters, and visit the Charles Darwin Research Station. Experience the beauty of Cotopaxi, Llanganates National Park and the Amazon Jungle, with thrilling activities like mountain biking, rafting, and volcanic hikes, before relaxing in Papallacta’s hot springs.
Explorer
Tour Type
Small Group TourSmall group tours usually have 8-12 participants and maximum up to 18 travelers
Accommodation
Home-stay, Hotel, Lodge
Age Range
18-80 yrs
Operated in
english
Destinations
Quito, Puerto Quito, Amazon Ecua
Quito, Puerto Quito, Amazon Ecuador, Papallacta, Puerto Villamil, Isla Santa Cruz, Banos
Active travelers looking to combine the stunning wildlife of the Galápagos Islands with the deep history of Peru’s Inca Trail should explore this incredible 17-day adventure. Stay onshore while visiting lesser-visited islands and spending your days with playful sea lions, majestic manta rays, and the famous Galápagos tortoise. Then, head to Peru and take on the iconic 4-day Inca Trail trek to Machu Picchu, surrounded by mountainscapes, cloud forests, and jungle views. This is a journey that will inspire and impress at every turn.
Explorer
Tour Type
Small Group TourSmall group tours usually have 8-12 participants and maximum up to 18 travelers
Accommodation
Guest House, Hotel, Camping
Age Range
12-100 yrs
Operated in
english
Destinations
Cusco, Quito, Lima, Ollantaytamb
Cusco, Quito, Lima, Ollantaytambo, Inca Trail, Isla Santa Cruz, Floreana Island, Isabela Island
This 11-day group tour travels from Quito in Ecuador to Cusco in Peru. Enjoy a three-night stay on Santa Cruz Island in the Galapagos, with time for snorkelling and hiking. Spot giant tortoises roaming in the highlands and swim with turtles and sea lions before heading to the Peruvian capital. Uncover the sights of the 'City of Kings' and meet indigenous people in the Sacred Valley. Explore Cusco independently or on an optional tour, and take the train to Machu Picchu, one of the New Seven Wonders of the World.
Explorer
Tour Type
Small Group TourSmall group tours usually have 8-12 participants and maximum up to 18 travelers
Accommodation
Hotel
Age Range
18-80 yrs
Operated in
english
Destinations
Cusco, Quito, Isla Santa Cruz, L
Cusco, Quito, Isla Santa Cruz, Lima, Sacred Valley
This 11-day group tour travels from Quito in Ecuador to Cusco in Peru. Enjoy a three-night stay on Santa Cruz Island in the Galapagos, with time for snorkelling and hiking. Spot giant tortoises roaming in the highlands and swim with turtles and sea lions before heading to the Peruvian capital. Uncover the sights of the 'City of Kings' and meet indigenous people in the Sacred Valley. Explore Cusco independently or on an optional tour, and take the train to Machu Picchu, one of the New Seven Wonders of the World.
Explorer
Tour Type
Small Group TourSmall group tours usually have 8-12 participants and maximum up to 18 travelers
Accommodation
Hotel
Age Range
18-80 yrs
Operated in
english
Destinations
Cusco, Quito, Isla Santa Cruz, L
Cusco, Quito, Isla Santa Cruz, Lima, Sacred Valley
Experience Ecuador in full glory, where the mainland combines natural and cultural wonders, and the Galapagos islands offer unrivalled wildlife watching. Beginning in Quito, we gaze over Cotopaxi volcano, experience indigenous culture and spend two nights in the Amazon Rainforest. It’s then off to the Galapagos, where we snorkel with sea lions, walk among giant tortoises and sunbathe on white sands with marine iguanas.
Wildlife
Tour Type
Small Group TourSmall group tours usually have 8-12 participants and maximum up to 18 travelers
Accommodation
Hotel, Lodge
Age Range
16-99 yrs
Operated in
english
Destinations
Quito, Floreana Island, Isla San
Quito, Floreana Island, Isla Santa Cruz, Banos, Tena, Liana Lodge, Papallacta, La Loberia, Playa Ochoa
GALAPAGOS CRUISE - CENTRAL, NORTH, EAST & WEST ISLANDS: Explore the stunning Galapagos on a 12-day island cruise. Encounter sunbathing sea lions in Elizabeth Bay, spot marine iguanas on Fernandina Island, and discover Galapagos Sea turtles near Bartolome Island. Enjoy scenic hikes to see volcanoes, breath-taking panoramic views and the iconic Pinnacle Rock. Encounter more sea lions on South Plaza and Lobos Island, and get up close with the wildlife of Santa Fe and San Cristobal Island. Begin and end your adventure with a night in Quito, Ecuador's charming capital.
Explorer
Tour Type
Small Group TourSmall group tours usually have 8-12 participants and maximum up to 18 travelers
Accommodation
Hotel
Age Range
18-80 yrs
Operated in
english
Destinations
Quito, Genovesa Island, South Pl
Quito, Genovesa Island, South Plaza Island, San Cristobal Island, Galapagos Islands, Isla Isabela, Moreno Point, Darwin Bay, Isla Fernandina, Isla Santiago, Sombrero Chino, Isla Santa Cruz
Get ready for an unforgettable journey through Ecuador, the Galapagos Islands, and Peru. Over 10 days, you’ll explore breathtaking landscapes, encounter unique wildlife, and immerse yourself in rich cultural heritage.
Your adventure begins in Quito, Ecuador, where colonial charm meets modern vibrancy. From there, you’ll fly to the Galapagos Islands, a natural wonderland teeming with wildlife. Kayak alongside sea lions, snorkel with hammerhead sharks, and hike volcanic trails.
Next, travel to Peru, where you’ll uncover the mysteries of the Inca Empire. Explore Cusco’s ancient ruins, marvel at the Sacred Valley, and stand in awe of Machu Picchu, the Lost City of the Incas. Your journey concludes in Lima, where history and culture come alive in its vibrant streets.
SnorkelingCity sightseeing
Tour Type
Small Group TourSmall group tours usually have 8-12 participants and maximum up to 18 travelers
Age Range
8-79 yrs
Operated in
english, spanish
Destinations
Cusco, Machu Picchu, Quito, Lima
Cusco, Machu Picchu, Quito, Lima, Guayaquil, Ollantaytambo, Pisac, Aguas Calientes, Isla Santa Cruz, San Cristobal Island, Bartolome Island
GALAPAGOS CRUISE: CENTRAL, SOUTH, EAST & NORTH ISLANDSEncounter sea lion colonies basking on pristine beaches, giant tortoises, iguanas, blue footed boobies and more in the wildlife rich Galapagos islands, on this once in a lifetime 8 day cruise around the remote and beautiful volcanic islands which once inspired Darwin himself. Spending a night before and after the cruise in captivating Quito.
Sailing, yachting and motor boating
Tour Type
Small Group TourSmall group tours usually have 8-12 participants and maximum up to 18 travelers
Accommodation
Hotel
Age Range
18-80 yrs
Operated in
english
Destinations
Quito, Isla Santa Cruz, Genovesa
Quito, Isla Santa Cruz, Genovesa Island, Santa Fe Island, San Cristobal Island, Espanola Island, Floreana Island