10 Best Andes Multiday Tours in September 2025

Puerto Maldonado Amazon Budget Eco-Lodge 6D/5N (from Cuzco) - September 2025

No booking fees

Best price guaranteed

Embark on an exhilarating journey from the ancient city of Cusco to the heart of the Amazon rainforest. Experience the captivating wildlife, dramatic landscapes, and the vibrant culture of Peru. Canoe through Lake Sandoval, zip-line through the treetops, and explore serene jungle paths. Conclude your adventure in the mystical city of Cusco, a gateway to Peru's rich history.

AdventureWildlife

Tour Type

Small Group Tour

Accommodation

Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Puerto Maldonado, Amazon Lodge Tambopata

Duration6 days

From

USD 596

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Huayhuash Express 6D/5N - September 2025

No booking fees

Best price guaranteed

Embark on a breathtaking trekking adventure through the stunning Peruvian Andes with this all-inclusive Huayhuash circuit. Traverse picturesque landscapes, encounter crystal-clear alpine lakes, and gain exclusive insights into local culture. Perfect for avid hikers seeking an unforgettable, high-altitude experience, this guided expedition offers challenging trails and awe-inspiring vistas. With experienced guides, delicious meals, and comfortable campsites, immerse yourself in nature's splendor while creating lifelong memories on this top-rated trek in Peru's renowned mountain sanctuary.

AdventureTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Tent, Camping, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Huaraz, Matacancha, Laguna Jahuacocha

Duration6 days

From

USD 1,457

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Crossing Northwest Argentina's Valleys and Ravines - September 2025

No booking fees

Best price guaranteed

Embark on a captivating 9-day journey through Northwest Argentina, where you will encounter stunning natural landscapes and vibrant cultural sites. From the bustling colonial city of Salta to the tranquil, picturesque towns of Cachi and Cafayate, this trip offers a rich tapestry of experiences. Traverse the breathtaking Quebrada de Humahuaca, explore the mesmerizing Salinas Grandes, and savor local wines in Cafayate. Designed with a perfect blend of adventure and relaxation, this itinerary offers both guided exploration and ample leisure time. Experience Argentina’s northwest like never before with Baboo's thoughtful curation, ensuring a memorable cultural immersion.

Skiing and Snowboarding

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Salta, Cachi, Cafayate, The Quebrada Valley

Duration9 days

From

USD 5,542

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Puerto Maldonado Amazon Eco-Lodge 6D/5N (from Cuzco) - September 2025

No booking fees

Best price guaranteed

Embark on an enchanting journey where the mysteries of the Amazon rainforest meet the timeless charm of Cusco. From exploring the lush jungles of Puerto Maldonado to discovering the rich tapestry of cultures in Cusco, this six-day expedition offers an array of unforgettable experiences. Journey through diverse ecosystems, witness extraordinary wildlife, engage in authentic cultural activities, and retreat in serene accommodations—each moment crafted for adventurous souls.

AdventureWildlife

Tour Type

Small Group Tour

Accommodation

Lodge, Bungalow, Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Cusco, Puerto Maldonado, Amazon Lodge Tambopata

Duration6 days

From

USD 740

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Uyuni Salt Flats & Desert Adventure 3D/2N (Uyuni to Uyuni) - September 2025

3.5

(2 reviews )

No booking fees

Best price guaranteed

Discover the breathtaking Uyuni Salt Flats with Bamba’s unforgettable adventure. This Bolivia tour offers an extraordinary journey through the world's largest salt flats, mesmerizing deserts, and colorful lagoons. Witness stunning sunsets, surreal landscapes, and local wildlife in their natural habitat. Capture perfect photos with creative perspective shots and marvel at the famous train cemetery. Experience local culture in traditional villages and stay in a unique salt hotel. This is the must-do Uyuni tour for adventure seekers and nature enthusiasts!

Desert safaris

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

Uyuni, Agencha, Polques

Duration3 days

From

USD 345

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Salkantay Trek & Machu Picchu - September 2025

(1 review )

Trip customizable

Best price guaranteed

Worried that you could not get the permit for the Inca Trail? We bring to you an opportunity to participate in an equally exhilarating journey through the Andes all the way down to Machu Picchu. Join us on this 4-day trek and travel through a variety of landscapes, ranging from snowcapped mountains to tropical forests and finally dense jungles, past small villages, towns and highland pastures, skirting herds of llamas en route. Cross the Salkantay Pass (4650m). Enjoy the serene beauty of Humantay Lake (4200). And visit some of the most important Inca sites in Peru, including the majestic Machu Picchu. If you are planning for a trekking trip in Peru along with a visit to Machu Picchu and you want to travel off the beaten path while appreciating the beautiful and diverse nature of Peru, then this trek is for you.

Trekking and Hiking

Tour Type

Group Tour

Accommodation

Camping, Hotel

Age Range

5-79 yrs

Operated in

english

Destinations

Salkantay, Cusco, Machu Picchu

Salkantay, Cusco, Machu Picchu, Soraypampa, Chaullay, Aguas Calientes

Duration4 days

From

USD 695

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Puerto Maldonado Amazon Field Station 3D/2N (from Puerto Maldonado) - September 2025

(4 reviews )

No booking fees

Best price guaranteed

Excellent experience, well organized - all the team was super - thank you Gladys and Frank - the ranger - for your marvelous insight.

Rainforest and jungle visits

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Puerto Maldonado, Amazon Lodge Tambopata

Duration3 days

From

USD 364

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Uyuni Salt Flats & Desert Adventure 5D/4N (La Paz to La Paz) - September 2025

(2 reviews )

No booking fees

Best price guaranteed

Embark on a captivating expedition through Uyuni’s mesmerising landscapes, including the enchanting Train Cemetery, dazzling salt flats, vibrant lagoons, and striking geologic formations. Witness spectacular wildlife like flamingos, relax in soothing thermal waters, and spend immersive nights in the singular salt hotel and a remote hostel. This journey promises a blend of natural wonders and cultural richness, offering an unforgettable experience.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Uyuni, Candelaria, Polques

Duration5 days

From

USD 480

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Inca Jungle trail to Machu Picchu: Biking and Hiking - September 2025

No booking fees

Best price guaranteed

The Inca Jungle trek to Machu Picchu is by far the most adventurous trekking option in the Cusco region. It is also the most varied in terms of activities. The Inca Jungle Trail adventure includes sections of biking and on foot, crossing mountains, valleys, rivers, indigenous towns, cocoa and coffee plantations, and a huge variety of fruit trees on this 4-day route. You will also soak in healthy and relaxing hot springs before finishing this amazing adventure in Machu Picchu. The Inca Jungle Trail is a very good alternative for the classic Inca Trail, which is usually very busy or sold out months in advance.

Trekking and Hiking

Tour Type

Private Tour

Accommodation

Hotel, Hostel, Guest House

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Cusco, Machu Picchu, Santa Teresa

Duration4 days

From

USD 399

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Easter Island Experience 4D/3N - September 2025

(1 review )

No booking fees

Best price guaranteed

Discover the ancient wonders of Easter Island with an immersive adventure that showcases iconic moai statues, volcanic landscapes, and rich cultural heritage. Embark on guided tours to Rano Raraku, Orongo Ceremonial Village, and Anakena Beach, uncovering the mysteries of this remote Pacific island. Enjoy unique encounters with local traditions, folklore, and breathtaking natural beauty. This unforgettable journey offers a perfect blend of history, stunning vistas, and authentic experiences, making it a must-visit for travel enthusiasts seeking extraordinary destinations.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Easter Island, Ahu Akivi, Anaken

Easter Island, Ahu Akivi, Anakena Beach, Orongo, Hanga Roa

Duration4 days

From

USD 1,044

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Ancasccocha trek to Machu Picchu 5d/4n - September 2025

(1 review )

No booking fees

Best price guaranteed

Excellent from Start to finish, fantastic crew, guide, food, scenery, information, far surpassed our expectations, would recommend to anyone.

Trekking and HikingMountains

Tour Type

Group Tour

Accommodation

Hotel, Tent, Camping

Age Range

5-70 yrs

Operated in

english, peruvian

Destinations

Ancascocha trek, Cusco, Machu Pi

Ancascocha trek, Cusco, Machu Picchu, Wat’a, Moyoc, Carr Cachicata, Aguas Calientes

Duration5 days

From

USD 690

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Colca Canyon Trekking 3D/2N & Transfer to Puno - September 2025

(1 review )

No booking fees

Best price guaranteed

Embark on an unforgettable adventure with a trek through Colca Canyon, one of the world's deepest canyons. Witness breathtaking landscapes, diverse wildlife, and traditional Andean culture. Enjoy mesmerizing views of soaring condors and relax in natural hot springs. Conclude your trip with a seamless transfer to Puno, offering a perfect combination of high-altitude trekking, cultural immersion, and spectacular scenery. This immersive experience is ideal for nature enthusiasts seeking an authentic taste of Peru's rugged beauty.

ExplorerTrekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel, Home-stay, Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

Puno, Arequipa, Colca Canyon

Duration3 days

From

USD 241

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Galapagos Island Hopping Adventure 5D/4N - September 2025

(1 review )

No booking fees

Best price guaranteed

Discover the wonders of the Galapagos Islands with an unforgettable adventure that includes exploring pristine beaches, snorkeling with vibrant marine life, and visiting iconic landmarks like the Charles Darwin Station. This island-hopping journey offers unique encounters with diverse wildlife, from giant tortoises to playful sea lions. Enjoy guided tours, fascinating hikes, and tranquil beach time, all while soaking in the rich natural beauty and unique ecosystem of this UNESCO World Heritage site. Perfect for nature enthusiasts and adventure seekers alike!

Beach

Tour Type

Small Group Tour

Accommodation

Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

Galapagos Islands, Baltra Island

Galapagos Islands, Baltra Island, Isla Santa Cruz, Santa Fe Island, San Cristobal Island, Isla Lobos

Duration5 days

From

USD 1,595

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Patagonian star: Perito Moreno Glacier - September 2025

4.9

(13 reviews )

Trip customizable

Best price guaranteed

The tour and the guide provided by the team were amazing. Their knowledge of the region and the Perito Moreno Glacier was invaluable, and I felt well-informed about what to expect during my visit. Great job.

GlaciersNational parks

Tour Type

Private Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

El Calafate, Perito Moreno Glacier

Duration3 days

From

USD 530

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All Andes Tours in September 2025

Page 5 of 228 Trips in Andes during September 2025 with 275 Reviews

Puerto Maldonado Amazon Budget Eco-Lodge 6D/5N (from Cuzco) - September 2025

Huayhuash Express 6D/5N - September 2025

Crossing Northwest Argentina's Valleys and Ravines - September 2025

Puerto Maldonado Amazon Eco-Lodge 6D/5N (from Cuzco) - September 2025

Uyuni Salt Flats & Desert Adventure 3D/2N (Uyuni to Uyuni) - September 2025

Salkantay Trek & Machu Picchu - September 2025

Puerto Maldonado Amazon Field Station 3D/2N (from Puerto Maldonado) - September 2025

Uyuni Salt Flats & Desert Adventure 5D/4N (La Paz to La Paz) - September 2025

Inca Jungle trail to Machu Picchu: Biking and Hiking - September 2025

Easter Island Experience 4D/3N - September 2025

Ancasccocha trek to Machu Picchu 5d/4n - September 2025

Colca Canyon Trekking 3D/2N & Transfer to Puno - September 2025

Galapagos Island Hopping Adventure 5D/4N - September 2025

Patagonian star: Perito Moreno Glacier - September 2025

Page 5 of 228 Trips in Andes during September 2025 with 275 Reviews

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Food, wine, events and nightlife

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Special interests and hobbies

All Andes Tours in September 2025

Page 5 of 228 Trips in Andes during September 2025 with 275 Reviews

Page 5 of 228 Trips in Andes during September 2025 with 275 Reviews