10 Best Andes Multiday Tours in October 2025

8-Day Argentina & Patagonia Tour From Buenos Aires: El Calafate & Ushuaia - October 2025

Trip customizable

Best price guaranteed

Embark on a Patagonian adventure, starting with 1 night in Buenos Aires to explore the city. Then, spend 3 nights each in El Calafate and Ushuaia. Discover the wild beauty of Patagonia, with its snowy peaks, scenic lakes, and captivating beaver dams. Tour the heart of Los Glaciares National Park for an unforgettable experience

Natural landmarks sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires, Tierra Del Fuego

Buenos Aires, Tierra Del Fuego, El Calafate, Perito Moreno Glacier, Ushuaia, Escondido

Duration8 days

From

USD 4,024

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Super Sales

Argentina, Uruguay and Brazil Discovery - October 2025

No booking fees

Best price guaranteed

Treat yourself to the finer things in life as you sip Copacabana Beach cocktails in Rio, shop the Tango District antique markets in Buenos Aires and unwind at a spa hotel, overlooking the mists of the Iguazú Falls in Argentina. In the vineyards of Juanicó winery, stop to sample the flavours of Uruguay’s revered wine region. Cross the Rio de la Plata to explore the UNESCO World heritage city of Colonia del Sacramento, before journeying onwards to Iguassu Falls and on to Rio de Janeiro. Follow in the footsteps of your Local Expert for an exclusive guided tour of the Rio Botanical Garden, a precious collection of the world’s oldest trees and exotic orchids.

City sightseeing

Tour Type

Group Tour

Accommodation

Hotel, Luxury Hotel

Age Range

5-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Mo

Buenos Aires, Rio de Janeiro, Montevideo, Iguassu National Park, Iguassu Falls

Duration11 days

From

USD 6,504

USD 6,309

Saving

USD 195

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Essential South America featuring Chile, the Mendoza Wine Region & Buenos Aires - October 2025

No booking fees

Best price guaranteed

Experience the essence of two South American countries on a comprehensive journey from Santiago, Chile to Argentina’s wine country and vibrant Buenos Aires. Stroll through Santiago’s Central Market, picking up fresh ingredients to incorporate in a seafood lunch. Spend two nights in Mendoza, South America’s famous wine country. Discover the rhythm of Buenos Aires and learn to tango with the best. In the Pampas of Argentina, explore gaucho culture and spend a day on a traditional estancia. Encounter the history and culture of Chile and Argentina in capital cities and the sprawling countryside.

Cultural, religious and historic sites

Tour Type

Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Mendoza

Duration10 days

From

USD 4,099

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Machu Picchu, Titicaca & La Paz - 12 days - October 2025

No booking fees

Best price guaranteed

Private tour: Travel from Lima to La Paz on this 12 day tour, taking in the highlights of Peru before crossing into Bolivia to visit the charming lakeside town of Copacabana and the world's highest capital city. Discover the delights of Lima, Cusco and La Paz on guided city tours and take a boat trip on Lake Titicaca to meet the islanders. Explore Pisac and Ollantaytambo Fortress in the beautiful Sacred Valley and marvel at Machu Picchu, the spectacular lost city of the Incas.

Explorer

Tour Type

Private Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Lima, La Paz, Cusco, Sacred Vall

Lima, La Paz, Cusco, Sacred Valley, Puno

Duration12 days

From

USD 2,885

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Buenos Aires, Patagonia & Santiago - 11 days - October 2025

No booking fees

Best price guaranteed

On this 11-day group tour, explore Buenos Aires’ vibrant districts and iconic landmarks, enjoy a tango show, and marvel at the Perito Moreno Glacier in El Calafate. Experience the stunning landscapes of Torres del Paine National Park, including breathtaking viewpoints and the Cueva del Milodon Natural Monument. The tour includes a scenic boat ride through the Patagonian fjords and a hike to the impressive Serrano Glacier. The adventure ends in Santiago with guided sightseeing of the Chilean capital.

City sightseeingNational parks

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Santiago

Buenos Aires, Santiago, Santiago, El Calafate, Puerto Natales

Duration11 days

From

USD 2,795

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Buenos Aires, Patagonia & Santiago (Superior) - 11 days - October 2025

No booking fees

Best price guaranteed

Explorer

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Santiago

Buenos Aires, Santiago, Santiago, El Calafate, Perito Moreno Glacier, Puerto Natales

Duration11 days

From

USD 3,315

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Wonders of Peru & La Paz - 14 Days - October 2025

No booking fees

Best price guaranteed

Private tour: From Peru to Bolivia, Lima to La Paz, take a tour of some of the region's most fascinating destinations, starting with the captivating Peruvian capital of Lima. Learn about the incredible flora and fauna of the vast Amazon Jungle. Take a scenic train ride through the Andean mountains to reach the breathtaking 'lost city' of Machu Picchu and meet the indigenous people of the floating islands of Uros on Lake Titicaca. This 14 day tour ends with a visit to lakeside Copacabana before exploring the lofty city of La Paz.

Explorer

Tour Type

Private Tour

Accommodation

Bungalow, Hotel, Lodge

Age Range

18-80 yrs

Operated in

english

Destinations

Lima, La Paz, La Paz, Cusco, Pue

Lima, La Paz, La Paz, Cusco, Puerto Maldonado, Sacred Valley

Duration14 days

From

USD 3,505

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Lima to La Paz - 14 days - October 2025

No booking fees

Best price guaranteed

From Peru to Bolivia, Lima to La Paz, take a tour of some of the region's most fascinating destinations, starting with the captivating Peruvian capital of Lima. Learn about the incredible flora and fauna of the vast Amazon Jungle. Take a scenic train ride through the Andean mountains to reach the breathtaking 'lost city' of Machu Picchu and meet the indigenous people of the floating islands of Uros on Lake Titicaca. This 14 day tour ends with a visit to lakeside Copacabana before exploring the lofty city of La Paz.

Explorer

Tour Type

Small Group Tour

Accommodation

Bungalow, Hotel, Lodge

Age Range

18-80 yrs

Operated in

english

Destinations

Lima, La Paz, Puno, Puerto Maldo

Lima, La Paz, Puno, Puerto Maldonado, Cusco, Sacred Valley

Duration14 days

From

USD 3,485

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Incas, Titicaca & La Paz - 12 days - October 2025

No booking fees

Best price guaranteed

Travel from Lima to La Paz on this 12 day tour, taking in the highlights of Peru before crossing into Bolivia to visit the charming lakeside town of Copacabana and the world's highest capital city. Discover the delights of Lima, Cusco and La Paz on guided city tours and take a boat trip on Lake Titicaca to meet the islanders. Explore Pisac and Ollantaytambo Fortress in the beautiful Sacred Valley and marvel at Machu Picchu, the spectacular lost city of the Incas.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Lima, La Paz, Cusco, Sacred Vall

Lima, La Paz, Cusco, Sacred Valley, Puno

Duration12 days

From

USD 2,975

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Way to Rio - 10 days - October 2025

No booking fees

Best price guaranteed

Visit the spectacular Iguazu Falls before continuing on this 10 day adventure that takes you to the beautiful city of Curibita, historic Morretes, buzzing Sao Paulo and the legendary Rio de Janeiro. Get a real local experience using public transport between cities, with guided sightseeing and plenty of free time to explore at your own pace.

Explorer

Tour Type

Private Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Iguazu Falls, Rio de Janeiro, Cu

Iguazu Falls, Rio de Janeiro, Curitiba, Puerto Iguazu

Duration10 days

From

USD 2,785

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Patagonia, Peaks & Glaciers - 13 days - October 2025

No booking fees

Best price guaranteed

Immerse yourself in the natural scenery of Argentina and Chile’s most breathtaking landscapes. From cruising along the Argentino lake, taking in views of the jaw dropping Perito Moreno Glacier in El Calafate, to exploring the grandeur of Torres del Paine National Park, before finishing in the buzzing metropolis of Santiago de Chile.

Explorer

Tour Type

Private Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Santiago

Buenos Aires, Santiago, Santiago, El Calafate, Torres Del Paine

Duration13 days

From

USD 4,805

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Highlights of Bolivia - 9 days - October 2025

No booking fees

Best price guaranteed

Discover the highlights of Bolivia as you visit the Bolivian Highlands, colonial Potosi and the incredible salt flats in Uyuni where you stay in a hotel made entirely of salt! Explore the famous rock formations of the Valley of the Giants before finishing up in San Pedro de Atacama in Chile!

Explorer

Tour Type

Private Tour

Accommodation

Hotel, Villa

Age Range

18-80 yrs

Operated in

english

Destinations

La Paz, San Pedro De Atacama, Po

La Paz, San Pedro De Atacama, Potosi, Uyuni

Duration9 days

From

USD 4,875

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Best of Peru & Bolivia - 15 days - October 2025

No booking fees

Best price guaranteed

Discover the wonders of Peru and Bolivia on this 15 day private tour which starts in Lima and ends in lofty La Paz. Marvel at the legendary Machu Picchu - the Lost City of the Incas, meet the islanders on beautiful Lake Titicaca, explore the shimmering white plains of the Uyuni salt flats and more!

Explorer

Tour Type

Private Tour

Accommodation

Hotel, Lodge

Age Range

18-80 yrs

Operated in

english

Destinations

Lima, La Paz, Sucre, Uyuni, Sacr

Lima, La Paz, Sucre, Uyuni, Sacred Valley, Machu Picchu, Aguas Calientes, Cusco, Lake Titicaca

Duration15 days

From

USD 6,975

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Andean Discovery - 18 days - October 2025

No booking fees

Best price guaranteed

Discover the highlights of Chile, Bolivia and Argentina on this 18 day private tour, visiting Atacama and the otherworldly Valley of the Moon, Uyuni, the world's largest salt flat and the spectacular Iguazu Falls, before ending in the sultry capital of Buenos Aires.

Explorer

Tour Type

Private Tour

Accommodation

Hotel, Villa

Age Range

18-80 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Santiago

Buenos Aires, Santiago, Santiago, Tupiza, Purmamarca, Salta, Iguazu Falls, San Pedro De Atacama, Laguna Colorada, Uyuni

Duration18 days

From

USD 8,385

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All Andes Tours in October 2025

Page 9 of 1,310 Trips in Andes during October 2025 with 1,562 Reviews

8-Day Argentina & Patagonia Tour From Buenos Aires: El Calafate & Ushuaia - October 2025

Argentina, Uruguay and Brazil Discovery - October 2025

Essential South America featuring Chile, the Mendoza Wine Region & Buenos Aires - October 2025

Machu Picchu, Titicaca & La Paz - 12 days - October 2025

Buenos Aires, Patagonia & Santiago - 11 days - October 2025

Buenos Aires, Patagonia & Santiago (Superior) - 11 days - October 2025

Wonders of Peru & La Paz - 14 Days - October 2025

Lima to La Paz - 14 days - October 2025

Incas, Titicaca & La Paz - 12 days - October 2025

Way to Rio - 10 days - October 2025

Patagonia, Peaks & Glaciers - 13 days - October 2025

Highlights of Bolivia - 9 days - October 2025

Best of Peru & Bolivia - 15 days - October 2025

Andean Discovery - 18 days - October 2025

Page 9 of 1,310 Trips in Andes during October 2025 with 1,562 Reviews

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Andes Tours in October 2025

Page 9 of 1,310 Trips in Andes during October 2025 with 1,562 Reviews

Page 9 of 1,310 Trips in Andes during October 2025 with 1,562 Reviews