10 Best Andes Multiday Tours in October 2025

Buenos Aires to Rio de Janeiro (via Uruguay) Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Buenos Aires to Rio de Janeiro, journeying through the captivating landscapes of Uruguay. Discover vibrant cultures, stunning beaches, and iconic landmarks. Highlights include exploring Buenos Aires’ tango-filled streets, soaking in Montevideo’s rich history, and relaxing in Punta del Este’s luxurious resorts. End your trip basking in Rio’s energetic vibe and iconic Christ the Redeemer statue. Perfect for travelers seeking diverse experiences, this South American expedition promises breathtaking sights and unparalleled memories.

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hotel, Resort

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Sa

Buenos Aires, Rio de Janeiro, Sao Paulo, Paraty, Ilha Grande, Colonia, Montevideo, Punta Del Este, Florianopolis

Duration16 days

From

USD 1,372

View Tour

Peru and Ecuador Discovery Tour - October 2025

Trip customizable

Best price guaranteed

Embark on a 23-day adventure through Peru, Ecuador, and the Galapagos Islands, where diverse cultures, breathtaking landscapes, and unique wildlife await. Begin in Peru with Lima’s vibrant markets, culinary experiences, and a walk through its colonial and modern districts. Journey to Lake Titicaca, exploring ancient cultures on Taquile and Uros Islands. In Cusco, visit iconic Inca sites and discover the Sacred Valley, leading to the legendary Machu Picchu. Then, venture into the Amazon at Puerto Maldonado, exploring the rainforest and its exotic wildlife from a secluded jungle lodge. Next, wander through Quito, Ecuador’s colonial heart, and taste its famous chocolate. In the Galapagos, encounter giant tortoises, snorkel among sea lions, and trek volcanic trails on Isabela Island. Finally, unwind in Guayaquil, enjoying coastal sights and vibrant local life. Prepare to be captivated by the wonders of South America—an adventure of a lifetime awaits! See the itinerary section below for more details.

Food tours

Tour Type

Private Tour

Age Range

1-79 yrs

Operated in

English

Destinations

Cusco, Machu Picchu, Quito, Lima

Cusco, Machu Picchu, Quito, Lima, Puerto Maldonado, Puno, Galapagos Islands, Guayaquil, Amazon Peru, Sandoval Lake, Puerto Quito, Puerto Ayora, Isabela Island, Taquile Island, Sacred Valley

Duration23 days

From

USD 7,670

View Tour

12 Day Buenos Aires, Patagonia and Santiago de Chile - October 2025

Trip customizable

Best price guaranteed

This 12 days package takes you through Argentina & Chile's highlights. You’ll start your tour in Argentina's never-sleeping capital city of Buenos Aires before heading up south to the Patagonia, where you will discover the cities of Bariloche and Puerto Varas. From there, you’ll fly to Santiago de Chile and be marveled by the capital of Chile

City sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-79 yrs

Operated in

english

Destinations

Santiago, San Carlos de Bariloch

Santiago, San Carlos de Bariloche, Puerto Varas, Frutillar, Puerto Montt, Buenos Aires

Duration12 days

From

USD 5,471

View Tour

14-Day Journey through Argentina and Brazil - October 2025

Trip customizable

Best price guaranteed

Begin your journey in captivating Buenos Aires, rich in culture and architecture. Explore El Calafate, home to the renowned Perito Moreno Glacier. Venture north to witness the breathtaking Iguazú Falls from the Brazilian side. Conclude your trip in Rio de Janeiro, where iconic landmarks await your discovery. Experience Argentina and Brazil on this 14-day adventure, with transfers, excursions, and accommodation included

AdventureCity sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Gu

Buenos Aires, Rio de Janeiro, Guanabara Bay, El Calafate, Foz Do Iguacu, Iguassu National Park, Iguassu National Park

Duration14 days

From

USD 6,080

View Tour

Patagonian Explorer Cruise - October 2025

Trip customizable

Best price guaranteed

This land and cruise tour will take you to see the marvels of two iconic South American cities and to the Fjords of Tierra del Fuego in Patagonia. Start this adventure in Santiago, a beautiful cosmopolitan city where you will see Santiago’s most important sites like Plaza de Armas, Modena Palace, Santa Lucía Hill and Barrio Lastarria, the latest is famous for the cultural, inherited and gastronomical options. Continue to Punta Arenas from where you will board your cruise to explore Patagonia. During this cruise you will see the fjords of the southern edge of Tierra del Fuego. Sail the Strait of Magellan into the labyrinth of channels from where you will see the highlights and most important sites and glaciers of the region, you will also visit Wulaia Bay and Cape Horn, known as the “End of the Earth”. After this wonderful cruise in Patagonia, you will disembark in Ushuaia from where you will fly to your last stop, Buenos Aires where you’ll have the chance to explore many of the city’s intriguing and varied neighbourhoods and learn about their culture and history before your tour ends.

CruiseCity sightseeing

Tour Type

Independent Tour

Accommodation

Hotel, Ship Cabin

Age Range

8-99 yrs

Operated in

English

Destinations

Buenos Aires, Punta Arenas, Ushu

Buenos Aires, Punta Arenas, Ushuaia, Wulaia Bay, Pia Glacier, Cóndor Glacier, Santiago

Duration6 days

From

USD 3,097

View Tour

Cruising Fjords of Tierra Del Fuego - October 2025

Trip customizable

Best price guaranteed

This 07-day land and cruise tour will take you to see the marvels of two iconic South American cities and to the Fjords of Tierra del Fuego in Patagonia. Start this adventure in Santiago, a beautiful cosmopolitan city where you will see Santiago’s most important sites like Plaza de Armas, Modena Palace, Santa Lucía Hill and Barrio Lastarria, the latest is famous for the cultural, inherited and gastronomical options. Continue to Punta Arenas from where you will board your cruise to explore Patagonia. During this cruise you will see the fjords of the southern edge of Tierra del Fuego. Sail the Strait of Magellan into the labyrinth of channels from where you will see the highlights and most important sites and glaciers of the region, you will also visit Wulaia Bay and Cape Horn, known as the “End of the Earth”. After this wonderful cruise in Patagonia, you will disembark in Ushuaia from where you will fly to your last stop, Buenos Aires where you’ll have the chance to explore many of the city’s intriguing and varied neighbourhoods and learn about their culture and history before your tour ends.

Cruise

Tour Type

Independent Tour

Accommodation

Hotel, Ship Cabin

Age Range

8-99 yrs

Operated in

English

Destinations

Buenos Aires, Punta Arenas, Glac

Buenos Aires, Punta Arenas, Glacier Alley, Cape Horn

Duration6 days

From

USD 2,834

View Tour

Buenos Aires to Santiago (via Mendoza) Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable journey from Buenos Aires to Santiago, immersing yourself in local culture and breathtaking landscapes. Enjoy wine tasting in Argentina's famed Mendoza region, marvel at the Andes’ majestic beauty, and discover vibrant cities bursting with history, art, and gastronomy. Perfect for adventure seekers and culture enthusiasts, this travel pass offers a seamless blend of city life and scenic wonders. Don't miss this chance to explore South America's most dynamic destinations.

Explorer

Tour Type

Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Córdoba

Buenos Aires, Santiago, Córdoba, Mendoza

Duration7 days

From

USD 540

View Tour

22% OFF TODAY

Super Sales

Real Argentina to Brazil - October 2025

No booking fees

Best price guaranteed

Embark on a South American escapade from Buenos Aires to Rio de Janeiro on this 14-day adventure. Soak up the might of Argentina before crossing to the charming city of Colonia del Sacramento, then explore the lively Mercado del Puerto in Montevideo. Spend two nights getting to know the locals on an estancia (farm) in Uruguay, either chipping in with the chores or relaxing in the sun, then marvel at the majesty of Iguazu Falls. Finishing off in the paradise of Ilha Grande and the buzz of Rio de Janeiro, you’ll experience the many sides of South America.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-35 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Pa

Buenos Aires, Rio de Janeiro, Paraty, Ilha Grande, Montevideo, Estancia, Iguazu Falls

22% OFF TODAY

Duration14 days

From

USD 2,895

USD 2,247

Saving

USD 648

View Tour

Sao Paulo, Rio de Janeiro & Iguazu Falls - October 2025

Trip customizable

Best price guaranteed

Embark on an unforgettable 9-day journey through Brazil’s most iconic destinations: São Paulo, Rio de Janeiro, and Iguazu Falls. Start your adventure in São Paulo, Brazil's vibrant financial hub and cultural capital, where the bustling streets are alive with diverse culinary delights, world-class museums, and eclectic neighborhoods. Next, head to Rio de Janeiro, a dazzling coastal city renowned for its stunning beaches—Copacabana and Ipanema—the awe-inspiring 38-meter-high Christ the Redeemer statue atop Corcovado Hill, and the panoramic views from Sugar Loaf Mountain, accessible via thrilling cable car rides. Your journey culminates at the breathtaking Iguazu Falls, a natural wonder straddling the border between Brazil and Argentina. Marvel at the sheer power and beauty of 275 individual waterfalls, with the tallest, the 80-meter Devil’s Throat, offering an unforgettable spectacle. Iguazu Falls is truly one of the seven natural wonders of the world and a must-visit on any South American itinerary. This tour promises a perfect blend of urban excitement, natural beauty, and cultural immersion, showcasing the very best of Brazil’s diverse landscapes and vibrant cities.

Rainforest and jungle visits

Tour Type

Independent Tour

Age Range

1-79 yrs

Operated in

english, spanish

Destinations

Iguazu Falls, Sao Paulo, Rio de

Iguazu Falls, Sao Paulo, Rio de Janeiro, Iguazu Falls National Park, Foz De Iguazú, Foz Do Iguacu, Puerto Iguazu

Duration9 days

From

USD 2,610

View Tour

15-Day Journey Across Argentina & Peru - October 2025

Trip customizable

Best price guaranteed

Begin your journey in captivating Buenos Aires, then explore El Calafate and the renowned Perito Moreno Glacier. Next, visit Lima for the Museo Larco, and journey to Machu Picchu by Vistadome train. Embark on an unforgettable adventure, with transfers, excursions, guides, and accommodations included

AdventureCity sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires, Cusco, Lima, Machu

Buenos Aires, Cusco, Lima, Machu Picchu, El Tigre, El Calafate, Estancia

Duration15 days

From

USD 8,358

View Tour

Río de Janeiro and Iguazú Waterfalls - October 2025

Trip customizable

Best price guaranteed

Rio de Janeiro and Iguazu falls is a carefully crafted 7-day guided tour package that takes you from Rio de Janeiro in Brazil to Iguazu Falls in Argentina. Enjoy sunset walks along the famous beaches of Rio de Janeiro, visit the Sugar Loaf Mountain on a cable-car, and admire the majestic Iguazu Falls from both Argentina and Brazil. Accompanied by our expert guides, you will learn and explore all the hidden gems on a city sightseeing tour and stop for delicious food on the way. Enjoy unobstructed views of Guanabara Bay, Sugar Loaf and the Burle Marx gardens. This tour offers a great combination of nature and culture. Please see our itinerary for more details.

Rainforest and jungle visits

Tour Type

Independent Tour

Accommodation

Hotel

Age Range

1-79 yrs

Operated in

English

Destinations

Iguazu Falls, Rio de Janeiro, Pu

Iguazu Falls, Rio de Janeiro, Puerto Iguazu, Foz De Iguazú, Iguazu Falls

Duration7 days

From

USD 1,775

View Tour

Samba & Tango Air-Expedition 14D/13N (from Buenos Aires) - October 2025

No booking fees

Best price guaranteed

Embark on an exhilarating South American adventure with an exclusive air-expedition that takes you from Buenos Aires to the heart of Brazil and Argentina. Experience the vibrant cultures of Samba and Tango as you explore iconic landmarks, indulge in local cuisines, and immerse yourself in rich traditions. Highlights include scenic helicopter flights over Iguazu Falls, guided tours of Rio de Janeiro, and captivating dance performances. Perfect for culture enthusiasts and thrill-seekers, this journey guarantees unforgettable memories.

AdventureWalking tours

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Il

Buenos Aires, Rio de Janeiro, Ilha Grande, Puerto Iguazu, Foz Do Iguacu, Paraty

Duration14 days

From

USD 5,647

View Tour

11-Day Argentina & Peru Essential Tour - October 2025

Trip customizable

Best price guaranteed

Embark on an unforgettable adventure as we explore the enchanting cities of Buenos Aires, Lima, Cusco, and the awe-inspiring Machu Picchu during an immersive 11-day / 10-night journey. Don't let this opportunity slip away! Our "Essential Argentina and Perú" travel package includes accommodation, airport transfers and excursions

Trekking and Hiking

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires, Cusco, Ollantaytam

Buenos Aires, Cusco, Ollantaytambo, Lima

Duration11 days

From

USD 5,535

View Tour

Northern Argentina & Chile Tour - October 2025

Trip customizable

Best price guaranteed

Explore the vibrant cities of Salta and Cafayate, traverse the diverse landscapes of the Puna region and delve into the cultural wonders of Quebrada de Humahuaca with our 10-day partially guided Northern Argentina and Chile Tour. On this tour, you will have the chance to cross the majestic Andes and explore the arid expanse of the Atacama Desert in Chile, marvel at the famous multicolored hills, serene lagoons and surreal geological formations and discover the desert’s stark beauty and vast open spaces that offer a stark contrast to the lush valleys of Argentina. Please see our itinerary for more details.

ExplorerDeserts and canyons

Tour Type

Independent Tour

Age Range

1-79 yrs

Operated in

english, spanish

Destinations

Salta, Cafayate, Purmamarca, San

Salta, Cafayate, Purmamarca, San Pedro De Atacama, Calama, Moon Valley

Duration10 days

From

USD 2,700

View Tour

All Andes Tours in October 2025

Page 8 of 1,306 Trips in Andes during October 2025 with 1,562 Reviews

Buenos Aires to Rio de Janeiro (via Uruguay) Travel Pass - October 2025

Peru and Ecuador Discovery Tour - October 2025

12 Day Buenos Aires, Patagonia and Santiago de Chile - October 2025

14-Day Journey through Argentina and Brazil - October 2025

Patagonian Explorer Cruise - October 2025

Cruising Fjords of Tierra Del Fuego - October 2025

Buenos Aires to Santiago (via Mendoza) Travel Pass - October 2025

Real Argentina to Brazil - October 2025

Sao Paulo, Rio de Janeiro & Iguazu Falls - October 2025

15-Day Journey Across Argentina & Peru - October 2025

Río de Janeiro and Iguazú Waterfalls - October 2025

Samba & Tango Air-Expedition 14D/13N (from Buenos Aires) - October 2025

11-Day Argentina & Peru Essential Tour - October 2025

Northern Argentina & Chile Tour - October 2025

Page 8 of 1,306 Trips in Andes during October 2025 with 1,562 Reviews

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Andes Tours in October 2025

Page 8 of 1,306 Trips in Andes during October 2025 with 1,562 Reviews

Page 8 of 1,306 Trips in Andes during October 2025 with 1,562 Reviews