10 Best Andes Multiday Tours in October 2025

Northern Argentina & Chile Tour - October 2025

Trip customizable

Best price guaranteed

Explore the vibrant cities of Salta and Cafayate, traverse the diverse landscapes of the Puna region and delve into the cultural wonders of Quebrada de Humahuaca with our 10-day partially guided Northern Argentina and Chile Tour. On this tour, you will have the chance to cross the majestic Andes and explore the arid expanse of the Atacama Desert in Chile, marvel at the famous multicolored hills, serene lagoons and surreal geological formations and discover the desert’s stark beauty and vast open spaces that offer a stark contrast to the lush valleys of Argentina. Please see our itinerary for more details.

ExplorerDeserts and canyons

Tour Type

Independent Tour

Age Range

1-79 yrs

Operated in

english, spanish

Destinations

Salta, Cafayate, Purmamarca, San

Salta, Cafayate, Purmamarca, San Pedro De Atacama, Calama, Moon Valley

Duration10 days

From

USD 2,700

View Tour

Super Sales

Argentina, Uruguay and Brazil Discovery - October 2025

No booking fees

Best price guaranteed

Treat yourself to the finer things in life as you sip Copacabana Beach cocktails in Rio, shop the Tango District antique markets in Buenos Aires and unwind at a spa hotel, overlooking the mists of the Iguazú Falls in Argentina. In the vineyards of Juanicó winery, stop to sample the flavours of Uruguay’s revered wine region. Cross the Rio de la Plata to explore the UNESCO World heritage city of Colonia del Sacramento, before journeying onwards to Iguassu Falls and on to Rio de Janeiro. Follow in the footsteps of your Local Expert for an exclusive guided tour of the Rio Botanical Garden, a precious collection of the world’s oldest trees and exotic orchids.

City sightseeing

Tour Type

Group Tour

Accommodation

Hotel, Luxury Hotel

Age Range

5-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Mo

Buenos Aires, Rio de Janeiro, Montevideo, Iguassu National Park, Iguassu Falls

Duration11 days

From

USD 6,504

USD 6,309

Saving

USD 195

View Tour

10% OFF TODAY

Essential South America featuring Chile, the Mendoza Wine Region & Buenos Aires - October 2025

No booking fees

Best price guaranteed

Experience the essence of two South American countries on a comprehensive journey from Santiago, Chile to Argentina’s wine country and vibrant Buenos Aires. Stroll through Santiago’s Central Market, picking up fresh ingredients to incorporate in a seafood lunch. Spend two nights in Mendoza, South America’s famous wine country. Discover the rhythm of Buenos Aires and learn to tango with the best. In the Pampas of Argentina, explore gaucho culture and spend a day on a traditional estancia. Encounter the history and culture of Chile and Argentina in capital cities and the sprawling countryside.

Cultural, religious and historic sites

Tour Type

Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Mendoza

10% OFF TODAY

Duration10 days

From

USD 4,099

USD 3,699

Saving

USD 400

View Tour

18% OFF TODAY

Super Sales

Machu Picchu & Galapagos - October 2025

No booking fees

Best price guaranteed

Combine two of the great adventure destinations in one trip: Machu Picchu, one of the New Wonders of the World, and the wildlife-watching haven of the Galapagos Islands. Starting in Peru, we explore the Inca empire, first visiting Cuzco and the nearby ruins, before taking the train through mountains and cloud forest to the once-lost city of Machu Picchu – hiking a section of the Inca Trail if you wish. It’s then off to the Galapagos, exploring land and sea in search of sharks, giant tortoises, sea lions and more with an expert naturalist guide.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

16-99 yrs

Operated in

english

Destinations

Cusco, Quito, Floreana Island, I

Cusco, Quito, Floreana Island, Isla Santa Cruz, Ollantaytambo, Aguas Calientes, San Cristobal Island, Isla Lobos

18% OFF TODAY

Duration15 days

From

USD 7,498

USD 6,184

Saving

USD 1,314

View Tour

Lima to La Paz - 14 days - October 2025

No booking fees

Best price guaranteed

From Peru to Bolivia, Lima to La Paz, take a tour of some of the region's most fascinating destinations, starting with the captivating Peruvian capital of Lima. Learn about the incredible flora and fauna of the vast Amazon Jungle. Take a scenic train ride through the Andean mountains to reach the breathtaking 'lost city' of Machu Picchu and meet the indigenous people of the floating islands of Uros on Lake Titicaca. This 14 day tour ends with a visit to lakeside Copacabana before exploring the lofty city of La Paz.

Explorer

Tour Type

Small Group Tour

Accommodation

Bungalow, Hotel, Lodge

Age Range

18-80 yrs

Operated in

english

Destinations

Lima, La Paz, Puno, Puerto Maldo

Lima, La Paz, Puno, Puerto Maldonado, Cusco, Sacred Valley

Duration14 days

From

USD 3,485

View Tour

Incas, Titicaca & La Paz - 12 days - October 2025

No booking fees

Best price guaranteed

Travel from Lima to La Paz on this 12 day tour, taking in the highlights of Peru before crossing into Bolivia to visit the charming lakeside town of Copacabana and the world's highest capital city. Discover the delights of Lima, Cusco and La Paz on guided city tours and take a boat trip on Lake Titicaca to meet the islanders. Explore Pisac and Ollantaytambo Fortress in the beautiful Sacred Valley and marvel at Machu Picchu, the spectacular lost city of the Incas.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-80 yrs

Operated in

english

Destinations

Lima, La Paz, Cusco, Sacred Vall

Lima, La Paz, Cusco, Sacred Valley, Puno

Duration12 days

From

USD 2,975

View Tour

Iguazu Falls Tour - Private Services - October 2025

(2 reviews )

Trip customizable

Best price guaranteed

The Iguazu falls are so big and spectacular!!!! Hot weather, so many different greens and a blue sky. The hotel fades with the nature. It is located into the nature reserve, and it is very relaxing, including massages services. Very much recomended!

Rainforest and jungle visits

Tour Type

Independent Tour

Accommodation

Hotel

Age Range

1-79 yrs

Operated in

english, spanish

Destinations

Iguazu Falls, Puerto Iguazu, Igu

Iguazu Falls, Puerto Iguazu, Iguazu Falls National Park, Foz De Iguazú, Foz Do Iguazu, Iguazu Falls

Duration4 days

From

USD 720

View Tour

Northern Paradise, Short Break - October 2025

15% OFF TODAY

Super Sales

Northern Paradise, Short Break - October 2025

Trip customizable

Best price guaranteed

Relax on the beaches of northern Peru, during four days of sun and nature. Be surprised by the humpback whales that pass very close to the coast and learn about our marine species while swimming with turtles. Spend an unforgettable afternoon watching the sunset while enjoying delicious dishes based on fresh products from the ocean.

Active and outdoor

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

6-99 yrs

Operated in

english

Destinations

Piura, Mancora, Tumbes

15% OFF TODAY

Duration4 days

From

USD 377

USD 320

Saving

USD 56

View Tour

Journeys: Ecuador’s Amazon And Volcanoes - October 2025

22% OFF TODAY

Super Sales

Journeys: Ecuador’s Amazon and Volcanoes - October 2025

(8 reviews )

No booking fees

Best price guaranteed

We had unforgettable time on this tour. Elmer and Kevin really helpful, reliable, available and just superb! We loved every minute of it. Thank you!

Wildlife

Tour Type

Small Group Tour

Accommodation

Lodge, Hotel, Resort

Age Range

12-100 yrs

Operated in

english

Destinations

Quito, Amazon Ecuador, Otavalo

Quito, Amazon Ecuador, Otavalo, Papallacta, Tena, Banos

22% OFF TODAY

Duration9 days

From

USD 2,399

USD 1,861

Saving

USD 538

View Tour

Local Living Ecuador—amazon Jungle - October 2025

22% OFF TODAY

Super Sales

Local Living Ecuador—Amazon Jungle - October 2025

4.9

(24 reviews )

No booking fees

Best price guaranteed

What a fantastic trip from start to finish. Have made lifelong memories.

WildlifeKayaking and canoeing

Tour Type

Small Group Tour

Accommodation

Hut, Hotel, Lodge

Age Range

12-100 yrs

Operated in

english

Destinations

Quito, Amazon Ecuador, Tena

22% OFF TODAY

Duration7 days

From

USD 949

USD 736

Saving

USD 213

View Tour

Journeys: Highlights Of Bolivia - October 2025

27% OFF TODAY

Super Sales

Journeys: Highlights of Bolivia - October 2025

(7 reviews )

No booking fees

Best price guaranteed

Excellent choice. Vlad had been wonderful !

Natural landmarks sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

12-100 yrs

Operated in

english

Destinations

La Paz, Sucre, Potosi, Uyuni

27% OFF TODAY

Duration8 days

From

USD 2,799

USD 2,036

Saving

USD 763

View Tour

13% OFF TODAY

Super Sales

Essential Peru - October 2025

4.8

(175 reviews )

No booking fees

Best price guaranteed

Fantastic holiday , A real adventure. We saw sights I had only dreamed about. Every day there was something new to wonder at, from the desert at Nasca , to Machu Picchu to Colca Canyon. Fantastic.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel, Home-stay, Villa

Age Range

16-99 yrs

Operated in

english

Destinations

Lima, Amantani, Puno, Arequipa

Lima, Amantani, Puno, Arequipa, Ica, Nazca, Abancay, Cusco, Aguas Calientes, Machu Picchu

13% OFF TODAY

Duration15 days

From

USD 3,892

USD 3,400

Saving

USD 492

View Tour

Buenos Aires, El Calafate & Iguazu Falls - October 2025

4.5

(4 reviews )

No booking fees

Best price guaranteed

Your arrangements gave us exactly what we wanted. But we were surprised that this was not a group tour as we thought it would be. Each hotel and excursion was separate, as opposed to being with the same group and tour guide the whole time. However, it worked out fine. We especially loved the hotels selected by the tour company because they were centrally located and we could easily walk around the various cities.

Sightseeing ToursAdventure

Tour Type

Group Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Iguazu Falls, El C

Buenos Aires, Iguazu Falls, El Calafate, Perito Moreno Glacier, Puerto Iguazu, Iguazu Falls National Park

Duration10 days

From

USD 1,930

View Tour

Journeys: Explore Colombia - October 2025

22% OFF TODAY

Super Sales

Journeys: Explore Colombia - October 2025

(8 reviews )

No booking fees

Best price guaranteed

Amazing experience. Well organized, provided insightful and varied experiences, a good overview of Colombia., it?s history and culture.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

12-100 yrs

Operated in

english

Destinations

Bogota, Cartagena, Armenia, Medellin

22% OFF TODAY

Duration9 days

From

USD 3,349

USD 2,599

Saving

USD 750

View Tour

All Andes Tours in October 2025

Page 2 of 93 Trips in Andes during October 2025 with 379 Reviews

Northern Argentina & Chile Tour - October 2025

Argentina, Uruguay and Brazil Discovery - October 2025

Essential South America featuring Chile, the Mendoza Wine Region & Buenos Aires - October 2025

Machu Picchu & Galapagos - October 2025

Lima to La Paz - 14 days - October 2025

Incas, Titicaca & La Paz - 12 days - October 2025

Iguazu Falls Tour - Private Services - October 2025

Northern Paradise, Short Break - October 2025

Journeys: Ecuador’s Amazon and Volcanoes - October 2025

Local Living Ecuador—Amazon Jungle - October 2025

Journeys: Highlights of Bolivia - October 2025

Essential Peru - October 2025

Buenos Aires, El Calafate & Iguazu Falls - October 2025

Journeys: Explore Colombia - October 2025

Page 2 of 93 Trips in Andes during October 2025 with 379 Reviews

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Andes Tours in October 2025

Page 2 of 93 Trips in Andes during October 2025 with 379 Reviews

Page 2 of 93 Trips in Andes during October 2025 with 379 Reviews