10 Best Andes Multiday Tours in October 2025

Salta to La Paz Salt Flats Adventure 10D/9N - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from the vibrant culture of Salta to the mesmerizing Uyuni Salt Flats in Bolivia. This 10-day experience offers unique encounters with breathtaking Andean landscapes, ancient ruins, and indigenous villages. Highlights include traversing the awe-inspiring altiplano, marveling at surreal salt deserts, and exploring colorful lagoons teeming with flamingos. Perfect for thrill-seekers and culture enthusiasts, this tour promises an extraordinary blend of nature, history, and adventure for an unmatched South American escape.

AdventureWalking tours

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Salta, La Paz, San Pedro

La Paz, Salta, La Paz, San Pedro De Atacama, Uyuni

Duration10 days

From

USD 3,440

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Best Of Peru Argentina And Brazil - October 2025

4.7

(3 reviews )

Trip customizable

Best price guaranteed

Excellent, saw a lot and have difficulty choosing what was best. Guides, tours and accommodations were great!

Cultural, religious and historic sites

Tour Type

Group Tour

Accommodation

Hotel, Lodge

Age Range

8-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Sa

Buenos Aires, Rio de Janeiro, Sacred Valley, Lima, Iguazu Falls, Urubamba, Cusco, Puno

Duration14 days

From

USD 3,937

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Machu Picchu and Galapagos - October 2025

4.7

(13 reviews )

No booking fees

Best price guaranteed

Our leader in Peru, Nilton, was excellent , as was Roberto, our leader in Ecuador My only regret, was an aspect of our visit to Machu Piccu, it was somewhat rigid, in that it was restricted to the lower levels of the monument. I, and several other members of the group would very much like to have climbed to the top level , in order to gain more of an overview of the site

Active and outdoorWildlife

Tour Type

Small Group Tour

Accommodation

Hotel, Hostel

Age Range

16-99 yrs

Operated in

english

Destinations

Cusco, Guayaquil, Sierra Negra

Cusco, Guayaquil, Sierra Negra, Tintoreras Island, Galapagos Islands, Tortuga Bay, Quito, Aguas Calientes, Puerto Villamil

Duration15 days

From

USD 4,920

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Rio de Janeiro to Buenos Aires (via Iguazu) Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from the vibrant streets of Rio de Janeiro to the cultural heart of Buenos Aires, seamlessly connecting you through the awe-inspiring Iguazu Falls. This immersive travel pass offers unique experiences like exploring Brazil's iconic Christ the Redeemer, hiking the lush rainforest, and reveling in Argentina's vibrant tango scene. Perfect for wanderlust-driven explorers, this journey promises unparalleled natural beauty, cultural richness, and thrilling activities, ensuring memories that last a lifetime. Discover South America's best-kept secrets today!

AdventureActive and outdoor

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Pu

Buenos Aires, Rio de Janeiro, Puerto Iguazu, Ilha Grande, Paraty, Sao Paulo, Foz Do Iguacu

Duration12 days

From

USD 1,172

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Charming Peru and Colombia - October 2025

Trip customizable

Best price guaranteed

Take a trip to two of the most breathtaking countries in Latin America! With this 13-day small-group tour of Peru and Colombia, you will discover extraordinary attractions, sacred sites, and breathtaking landscapes which are full of history! Begin your tour in Lima, the "City of Kings" famous for its colonial architecture, extraordinary museums, and delicious cuisine. Catch a flight to Cusco and fly over the Andes Mountains, drive through the Urubamba Valley, and explore Machu Picchu, the Lost City of the Incas. Travel through the Sacred Valley of Peru and visit Cusco with a trip to the Santo Domingo Convent. From there you will fly to Bogota, the capital of Colombia and one of the highest capital cities in the world! Visit the Plaza de Bolívar and La Candelaria, two major city highlights, and enjoy the breathtaking views from Montserrate Hill. From there you will travel to the Coffee Triangle to learn about the rich cultural and natural heritage of the region. This is the perfect way to get acquainted with Colombia’s best-known secret — its delicious coffee. End your tour in Cartagena, a breathtaking coastal city in the Caribbean lowlands bordered by magnificent mountains and the Pacific Ocean. Discover the extraordinary lava beaches loved by locals and tourists!

Cultural, religious and historic sites

Tour Type

Group Tour

Accommodation

Hotel, Lodge

Age Range

8-99 yrs

Operated in

english

Destinations

Lima, Cartagena, Sacred Valley

Lima, Cartagena, Sacred Valley, Armenia, Urubamba, Cusco, Bogota

Duration13 days

From

USD 2,887

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Ushuaia to Santiago (Ruta 40) Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable Patagonian adventure from snow-capped Ushuaia to vibrant Santiago along iconic Ruta 40. Discover pristine landscapes, immersive cultural encounters, and thrilling outdoor activities. Highlights include exploring the picturesque Glacier National Park, hiking in stunning El Chaltén, and marveling at the surreal Atacama Desert. Dive into local Argentine and Chilean traditions while indulging in exceptional gastronomy. Experience the ultimate South American journey with diverse terrains, breathtaking vistas, and memorable moments tailored for adventurous travelers.

Active and outdoor

Tour Type

Group Tour

Accommodation

Hotel, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Ushuaia, Pucon, El Cal

Santiago, Ushuaia, Pucon, El Calafate, El Chalten, Perito Moreno Glacier, San Carlos de Bariloche, Puerto Varas

Duration12 days

From

USD 1,394

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Premium Chile & Argentina - October 2025

22% OFF TODAY

Super Sales

Premium Chile & Argentina - October 2025

No booking fees

Best price guaranteed

Against the magnificent backdrop of the Andes Mountains, journey from Santiago to Buenos Aires, taking in all the history, culture and cuisine in between. This nine-day Premium adventure will show you the heart of Chile and Argentina as you stroll the streets of Santiago with a local guide and sip piscos on a rooftop in the historic centre of Valparaiso. Sample some of the world’s best wine in Mendoza, stroll the stylish neighbourhoods of Buenos Aires and discover El Tigre Delta for an adventure to remember. Packed with Exclusive Experiences, historical Feature Stays and with a local leader by your side, you’ll fall for the vibrancy and indulgent atmosphere of this part of the world in no time.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Valparai

Buenos Aires, Santiago, Valparaiso, Mendoza

22% OFF TODAY

Duration9 days

From

USD 6,145

USD 4,769

Saving

USD 1,376

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Buenos Aires, Uruguay and Asunción Exploration - October 2025

Trip customizable

Best price guaranteed

Join us on an unforgettable journey through South America's vibrant cities and scenic landscapes. Begin your 12-day adventure from Montevideo, Uruguay, exploring the city's highlights, including its historic center, Independence Square, and the vibrant Prado neighborhood. Enjoy scenic views from Plaza Virgilio before a delightful dinner and tango show at Primuseum. Next, visit the Canelones wine region for a winery tour and tasting of Uruguay's famed Tannat wine. In Colonia del Sacramento, walk through its Unesco-listed historic district, immersing in its Portuguese heritage. Travel to Buenos Aires, the capital city of Argentina, to experience its dynamic culture, from historic Plaza de Mayo to colorful La Boca and elegant Recoleta. End with an enchanting dinner and tango show. A day in the Pampas reveals gaucho traditions and a traditional Argentine asado. Conclude your trip in Asunción, the capital city of Paraguay, exploring colonial landmarks and vibrant local markets, ensuring a memorable end to your South American adventure.

City sightseeing

Tour Type

Private Tour

Age Range

1-79 yrs

Operated in

english, spanish

Destinations

Buenos Aires, Montevideo, Coloni

Buenos Aires, Montevideo, Colonia Del Sacramento, Asuncion, Colonia

Duration12 days

From

USD 4,810

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14 Day Trip: Galapagos & Machu Picchu - October 2025

Trip customizable

Best price guaranteed

On this 14-day guided tour trip, you will visit the highlights of both Ecuador and Peru. Experience the highlights of the City of Quito, Cotopaxi National Park, the Galapagos Islands: Santa Cruz, El Chato, Charles Darwin Station, Pinzon Island / Isabela Island, Tintoreras, and Cabo Rosa Tunnels. In Peru, you will have the opportunity to get to know the highlights of the ancient Inca civilization. Explore the city of Cusco, the Sacred Valley, the mountain of colors, and Machu Picchu. Visit Inca structures, and learn about the historic Inca settlements and their history. You will be accompanied by a guide, who will assist you with anything you need. We will also provide you with transportation, accommodation and some meals.

Trekking and HikingWildlife

Tour Type

Group Tour

Accommodation

Hotel

Age Range

5-80 yrs

Operated in

english, spanish

Destinations

Cusco, Machu Picchu, Quito, Lima

Cusco, Machu Picchu, Quito, Lima, Galapagos Islands, Santa Cruz, Sacred Valley, Cotopaxi National Park, Mitad Del Mundo, Isla Isabela, Los Túneles

Duration14 days

From

USD 3,995

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Rio de Janeiro to Buenos Aires (via Florianopolis & Iguazu) Travel Pass - October 2025

No booking fees

Best price guaranteed

Discover the ultimate South American adventure with a journey from vibrant Rio de Janeiro to cosmopolitan Buenos Aires, featuring Florianopolis and Iguazu Falls. Experience the iconic beaches of Rio, the nightlife of Florianopolis, and the breathtaking beauty of Iguazu. This travel pass offers thrilling activities like samba shows in Rio, exploring Iguazu's immense waterfalls, and savoring Argentine cuisine in Buenos Aires. Immerse yourself in diverse cultures and stunning landscapes, making unforgettable memories along the way!

City sightseeingWaterfalls

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Fl

Buenos Aires, Rio de Janeiro, Florianopolis, Foz Do Iguacu, Puerto Iguazu, Ilha Grande, Paraty, Sao Paulo

Duration17 days

From

USD 1,288

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Buenos Aires to Rio de Janeiro (via Iguazu & Florianopolis) Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from vibrant Buenos Aires to picturesque Rio de Janeiro, traversing breathtaking Iguazu Falls and stunning Florianopolis. This immersive journey offers unique experiences like exploring Argentina's bustling capital, marveling at the thundering Iguazu Falls, and soaking up Florianopolis' beautiful beaches. End your tour with the iconic sights of Rio, including Christ the Redeemer and Copacabana Beach. This South American escapade combines urban excitement, natural wonders, and coastal relaxation, promising an enriching travel experience.

City sightseeingWaterfalls

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Sa

Buenos Aires, Rio de Janeiro, Sao Paulo, Paraty, Ilha Grande, Puerto Iguazu, Florianopolis, Curitiba

Duration15 days

From

USD 1,173

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Santiago to Buenos Aires (via Mendoza) Travel Pass - October 2025

No booking fees

Best price guaranteed

Discover an unforgettable adventure from Santiago to Buenos Aires, immersing yourself in the rich culture and breathtaking landscapes of South America. Journey through the scenic Andes, savor exquisite wines in Mendoza, and experience vibrant city life in Buenos Aires. This curated travel pass offers guided tours, diverse outdoor activities, and authentic local experiences. Perfect for wine enthusiasts and adventure seekers, this tour offers the ultimate blend of nature, culture, and culinary delights. Book now for an extraordinary South American escapade!

Adventure

Tour Type

Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Mendoza

Buenos Aires, Santiago, Mendoza, Córdoba

Duration7 days

From

USD 505

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Buenos Aires to Rio de Janeiro (via Iguazu) Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Buenos Aires to Rio de Janeiro via the natural marvels of Iguazu with Bamba travel. Experience vibrant tango nights, awe-inspiring Iguazu Falls, and the lively rhythm of Rio's Copacabana. Delight in cultural immersion, exquisite cuisine, and iconic landmarks as you traverse Argentina and Brazil. This travel pass promises unique experiences, from bustling city life to breathtaking natural wonders, perfect for adventurous explorers seeking the ultimate South American journey.

BeachWaterfalls

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Pa

Buenos Aires, Rio de Janeiro, Paraty, Ilha Grande, Puerto Iguazu, Foz Do Iguacu, Sao Paulo

Duration14 days

From

USD 1,116

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Machu Picchu & Galapagos Wonders featuring a 4-Night Cruise - October 2025

No booking fees

Best price guaranteed

Journey from the Land of the Incas to the Galápagos archipelago, enjoying a 4-night cruise aboard a personal yacht. Delve deep into ancient cultures at Machu Picchu – the fabled lost city. Explore UNESCO-designated Spanish colonial cities and stand between two hemispheres at the Equatorial Line. Experience the best of the Galápagos archipelago, where an abundance of natural wildlife recalls Darwin’s theories in a pristine world that’s virtually unspoiled. You’ll encounter hidden wonders in Peru, the “Middle of the World” in Ecuador, and see ethereal wildlife on a cruise along Eden-like islands.

Trekking and Hiking

Tour Type

Group Tour

Accommodation

Hotel, Ship Cabin

Age Range

1-99 yrs

Operated in

english

Destinations

Lima, Santa Cruz, Quito, Isabela

Lima, Santa Cruz, Quito, Isabela Island, Isla Santiago, Sacred Valley, Machu Picchu, Cuzco

Duration14 days

From

USD 8,099

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All Andes Tours in October 2025

Page 3 of 417 Trips in Andes during October 2025 with 796 Reviews

Salta to La Paz Salt Flats Adventure 10D/9N - October 2025

Best Of Peru Argentina And Brazil - October 2025

Machu Picchu and Galapagos - October 2025

Rio de Janeiro to Buenos Aires (via Iguazu) Travel Pass - October 2025

Charming Peru and Colombia - October 2025

Ushuaia to Santiago (Ruta 40) Travel Pass - October 2025

Premium Chile & Argentina - October 2025

Buenos Aires, Uruguay and Asunción Exploration - October 2025

14 Day Trip: Galapagos & Machu Picchu - October 2025

Rio de Janeiro to Buenos Aires (via Florianopolis & Iguazu) Travel Pass - October 2025

Buenos Aires to Rio de Janeiro (via Iguazu & Florianopolis) Travel Pass - October 2025

Santiago to Buenos Aires (via Mendoza) Travel Pass - October 2025

Buenos Aires to Rio de Janeiro (via Iguazu) Travel Pass - October 2025

Machu Picchu & Galapagos Wonders featuring a 4-Night Cruise - October 2025

Page 3 of 417 Trips in Andes during October 2025 with 796 Reviews

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Andes Tours in October 2025

Page 3 of 417 Trips in Andes during October 2025 with 796 Reviews

Page 3 of 417 Trips in Andes during October 2025 with 796 Reviews