10 Best Andes Multiday Tours in October 2025

Panama City to Bogota Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Panama City to Bogota, immersing yourself in vibrant cultures, lush landscapes, and rich histories. This seamless travel pass offers unique experiences, including exploring Panama Canal’s marvels, snorkeling in San Blas Islands’ crystal waters, discovering Medellín's urban transformation, and delving into Bogota’s dynamic arts scene. Perfect for thrill-seekers and culture enthusiasts, this tour promises a diverse blend of activities, ensuring an enriching journey through Central America's hidden gems and Colombia's enchanting urban hubs.

BeachSnorkelingExplorer

Tour Type

Group Tour

Age Range

18-99 yrs

Operated in

english

Destinations

Bogota, Panama City, San Blas Is

Bogota, Panama City, San Blas Islands, Medellin, Manizales, Hacienda Venecia Coffe Farm

Duration10 days

From

USD 1,629

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Rio de Janeiro to Santiago Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Rio de Janeiro to Santiago, exploring South America’s vibrant culture and breathtaking landscapes. Dive into lively Rio’s beaches, marvel at Iguazu Falls’ natural wonders, and revel in Buenos Aires’ rich history. Experience Chile’s scenic beauty in Colchagua Valley and the energetic atmosphere of Santiago. Perfect for thrill-seekers and cultural enthusiasts, enjoy unique excursions including wine tasting and tango dancing lessons. Discover the essence of South America with this curated travel experience.

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Rio de Janeiro, Floria

Santiago, Rio de Janeiro, Florianopolis, Foz Do Iguacu, Puerto Iguazu, Buenos Aires, Córdoba, Mendoza, Ilha Grande, Paraty, Sao Paulo

Duration21 days

From

USD 1,779

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Santiago to La Paz Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from Santiago to La Paz, exploring the heart of South America with Bamba Travel. Discover Chile’s vibrant culture and breathtaking landscapes, marvel at Bolivia's otherworldly salt flats, and journey through the Andes. This curated travel experience includes guided tours, vibrant city explorations, and thrilling excursions like Atacama Desert and Uyuni Salt Flats. Perfect for intrepid travelers seeking immersive cultural adventures and natural wonders. Book your South American escapade today for an unforgettable journey!

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, La Paz, Uyuni, Potosi

Santiago, La Paz, Uyuni, Potosi, Sucre, Valparaiso, La Serena, San Pedro De Atacama, Uyuni Salt Flat

Duration17 days

From

USD 1,164

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La Paz to Santiago Travel Pass - October 2025

No booking fees

Best price guaranteed

Discover an unforgettable adventure from La Paz to Santiago, exploring the heart of South America with unparalleled experiences. Traverse Bolivia, Peru, and Chile, diving into the vibrant cultures of each destination. This travel pass immerses you in unique activities like gazing at the Uyuni Salt Flats, exploring the Atacama Desert, and vibrant city vibes. Perfect for backpackers and culture enthusiasts seeking an authentic journey, this tour promises unforgettable memories and breathtaking landscapes. Book now for an epic South American odyssey!

Active and outdoorVolcanoes

Tour Type

Group Tour

Accommodation

Hotel, Hostel, Lodge, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, La Paz, San Pedro De A

Santiago, La Paz, San Pedro De Atacama, La Serena, Valparaiso, Sucre, Potosi, Uyuni, Agencha, Polques

Duration17 days

From

USD 1,257

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Buenos Aires To Rio Explorer - October 2025

13% OFF TODAY

Super Sales

Buenos Aires to Rio Explorer - October 2025

No booking fees

Best price guaranteed

Hug the eastern coastline of South America on this 17-day city, countryside and island adventure. Discover Buenos Aires’ eclectic markets at San Telmo, travel to Rio de Janeiro to soak up all the Brazilian party vibes and experience life on an estancia in Uruguay. You’ll have a local leader each step of the way to recommend the best beach or coolest bar, plus a small group of likeminded travellers to share your experiences with. Ready, set – let’s fiesta.

City sightseeingWaterfalls

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Il

Buenos Aires, Rio de Janeiro, Ilha Grande, Colonia Del Sacramento, Tacuarembo, Puerto Iguazu, Foz Do Iguazu, Iguazu Falls, Paraty

13% OFF TODAY

Duration17 days

From

USD 3,785

USD 3,304

Saving

USD 481

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Best Of Bolivia & Argentina - October 2025

27% OFF TODAY

Super Sales

Best of Bolivia & Argentina - October 2025

No booking fees

Best price guaranteed

Get exploring South America on a 15-day small-group experience that takes you deep into Bolivia and Argentina. Beginning in La Paz, journey from whimsical potion-filled markets through Sucre’s landscaped streets to the once-rich silver ore mines of Potosi. Take on the Bolivian desert as you embark on a 4WD adventure across the salt pans of Salar de Uyuni, winding up among the cactus-filled valleys of Bolivia’s wild west. Cross the border into Argentina to discover indigenous cultures in Tilcara, before spending a few days at leisure in the fiery capital of Buenos Aires. Local knowledge will lead the way, and plenty of freedom to explore will give you the power to see South America in your style.

City sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, La Paz, Tilcara, S

Buenos Aires, La Paz, Tilcara, Sucre, Potosi, Uyuni, Salar De Uyuni, San Pedro De Atacama

27% OFF TODAY

Duration15 days

From

USD 2,600

USD 1,892

Saving

USD 709

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Best Of Argentina, Uruguay & Brazil - October 2025

18% OFF TODAY

Super Sales

Best of Argentina, Uruguay & Brazil - October 2025

No booking fees

Best price guaranteed

Hug the eastern coastline of South America on a ten-day adventure. This down-to-earth adventure takes you from Buenos Aires to Rio de Janeiro via Colonia del Sacramento, an estancia and the spectacular Iguazu Falls. Embrace ranch life during your estancia stay and explore the grounds on horseback, wonder at the largest waterfall in the world and get a taste of Rio’s nightlife.

City sightseeing

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

15-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Co

Buenos Aires, Rio de Janeiro, Colonia Del Sacramento, Tacuarembo, Foz Do Iguazu, Iguazu Falls

18% OFF TODAY

Duration10 days

From

USD 2,990

USD 2,465

Saving

USD 525

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Santiago to Ushuaia (Ruta 40) Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable Patagonia adventure with Bamba’s epic journey from Santiago to Ushuaia. Traverse the legendary Ruta 40, experiencing breathtaking landscapes, majestic glaciers, and lush national parks. Hike in Torres del Paine, explore the vibrant streets of Buenos Aires, and witness the awe-inspiring Perito Moreno Glacier. This expertly curated tour offers immersive cultural experiences and unparalleled natural beauty, making it perfect for adventurous travelers seeking the ultimate South American expedition. Book now for an extraordinary travel experience.

Active and outdoorAdventure

Tour Type

Group Tour

Accommodation

Hotel, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Ushuaia, El Chalten, E

Santiago, Ushuaia, El Chalten, El Calafate, Pucon, Puerto Varas, San Carlos de Bariloche, Perito Moreno Glacier

Duration14 days

From

USD 1,562

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Salta to La Paz Salt Flats Adventure 10D/9N - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from the vibrant culture of Salta to the mesmerizing Uyuni Salt Flats in Bolivia. This 10-day experience offers unique encounters with breathtaking Andean landscapes, ancient ruins, and indigenous villages. Highlights include traversing the awe-inspiring altiplano, marveling at surreal salt deserts, and exploring colorful lagoons teeming with flamingos. Perfect for thrill-seekers and culture enthusiasts, this tour promises an extraordinary blend of nature, history, and adventure for an unmatched South American escape.

AdventureWalking tours

Tour Type

Small Group Tour

Accommodation

Hotel, Lodge

Age Range

18-99 yrs

Operated in

english

Destinations

La Paz, Salta, La Paz, San Pedro

La Paz, Salta, La Paz, San Pedro De Atacama, Uyuni

Duration10 days

From

USD 3,440

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Rio de Janeiro to Buenos Aires (via Iguazu) Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable adventure from the vibrant streets of Rio de Janeiro to the cultural heart of Buenos Aires, seamlessly connecting you through the awe-inspiring Iguazu Falls. This immersive travel pass offers unique experiences like exploring Brazil's iconic Christ the Redeemer, hiking the lush rainforest, and reveling in Argentina's vibrant tango scene. Perfect for wanderlust-driven explorers, this journey promises unparalleled natural beauty, cultural richness, and thrilling activities, ensuring memories that last a lifetime. Discover South America's best-kept secrets today!

AdventureActive and outdoor

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Pu

Buenos Aires, Rio de Janeiro, Puerto Iguazu, Ilha Grande, Paraty, Sao Paulo, Foz Do Iguacu

Duration12 days

From

USD 1,172

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Ushuaia to Santiago (Ruta 40) Travel Pass - October 2025

No booking fees

Best price guaranteed

Embark on an unforgettable Patagonian adventure from snow-capped Ushuaia to vibrant Santiago along iconic Ruta 40. Discover pristine landscapes, immersive cultural encounters, and thrilling outdoor activities. Highlights include exploring the picturesque Glacier National Park, hiking in stunning El Chaltén, and marveling at the surreal Atacama Desert. Dive into local Argentine and Chilean traditions while indulging in exceptional gastronomy. Experience the ultimate South American journey with diverse terrains, breathtaking vistas, and memorable moments tailored for adventurous travelers.

Active and outdoor

Tour Type

Group Tour

Accommodation

Hotel, Villa

Age Range

18-99 yrs

Operated in

english

Destinations

Santiago, Ushuaia, Pucon, El Cal

Santiago, Ushuaia, Pucon, El Calafate, El Chalten, Perito Moreno Glacier, San Carlos de Bariloche, Puerto Varas

Duration12 days

From

USD 1,394

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Super Sales

Real Peru to Bolivia - October 2025

No booking fees

Best price guaranteed

With a stay in the heart of the jungle, plenty of pisco sours and some hot and heavy hiking on the Inca Trail, this trip is 15 days of exploring, drinking, eating and sweating (nobody said the trail would be easy, but boy is it worth it). Experience the real Amazon in a proper jungle lodge, follow in the footsteps of ancient people on the Inca Trail to Wonder of the World Machu Picchu and stay with a local family who live in a mud-brick house on the shores of Lake Titicaca. Hit the nightlife in Cusco, sail down the Amazon River in the pitch-black of night (look out for jaguars!) and experience an I’m-so-far-from-home moment with some new friends on an epic trek through Peru to Bolivia.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel, Camping, Lodge, Home-stay

Age Range

18-35 yrs

Operated in

english

Destinations

Lima, La Paz, Puno, Lake Titicac

Lima, La Paz, Puno, Lake Titicaca, La Paz, Puerto Maldonado, Cusco, Ollantaytambo, Inca Trail

Duration15 days

From

USD 2,520

USD 2,444

Saving

USD 76

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Rio de Janeiro to Buenos Aires (via Florianopolis & Iguazu) Travel Pass - October 2025

No booking fees

Best price guaranteed

Discover the ultimate South American adventure with a journey from vibrant Rio de Janeiro to cosmopolitan Buenos Aires, featuring Florianopolis and Iguazu Falls. Experience the iconic beaches of Rio, the nightlife of Florianopolis, and the breathtaking beauty of Iguazu. This travel pass offers thrilling activities like samba shows in Rio, exploring Iguazu's immense waterfalls, and savoring Argentine cuisine in Buenos Aires. Immerse yourself in diverse cultures and stunning landscapes, making unforgettable memories along the way!

City sightseeingWaterfalls

Tour Type

Group Tour

Accommodation

Hotel

Age Range

18-99 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Fl

Buenos Aires, Rio de Janeiro, Florianopolis, Foz Do Iguacu, Puerto Iguazu, Ilha Grande, Paraty, Sao Paulo

Duration17 days

From

USD 1,288

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13% OFF TODAY

Super Sales

Real Bolivia to Brazil - October 2025

No booking fees

Best price guaranteed

Take an adventure in diverse South America on this 25-day trip from La Paz to Rio de Janeiro. See amazing natural wonders, walk the streets of busy cities and meet the charming locals with a leader by your side who knows all the best spots. Tour the city of Colonia del Sacramento, discover why Salta is nicknamed ‘La Linda’ (‘the beautiful’) and tick immersive Buenos Aires off your bucket list with your new group of friends. Witness the magic of the Iguazu Falls, journey through the untamed desert scenery of San Pedro de Atacama and see the otherworldly Salar de Uyuni salt flats. You’ll have plenty of free time to explore each location, and all the logistics are taken care of for you, so you can concentrate on making new connections and discovering new places.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-35 yrs

Operated in

english

Destinations

Rio de Janeiro, La Paz, Buenos A

Rio de Janeiro, La Paz, Buenos Aires, Montevideo, Estancia, Iguazu Falls, Paraty, Ilha Grande, Salar De Uyuni, Altiplano, San Pedro De Atacama, Salta

13% OFF TODAY

Duration25 days

From

USD 4,735

USD 4,134

Saving

USD 601

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All Andes Tours in October 2025

Page 2 of 241 Trips in Andes during October 2025 with 249 Reviews

Panama City to Bogota Travel Pass - October 2025

Rio de Janeiro to Santiago Travel Pass - October 2025

Santiago to La Paz Travel Pass - October 2025

La Paz to Santiago Travel Pass - October 2025

Buenos Aires to Rio Explorer - October 2025

Best of Bolivia & Argentina - October 2025

Best of Argentina, Uruguay & Brazil - October 2025

Santiago to Ushuaia (Ruta 40) Travel Pass - October 2025

Salta to La Paz Salt Flats Adventure 10D/9N - October 2025

Rio de Janeiro to Buenos Aires (via Iguazu) Travel Pass - October 2025

Ushuaia to Santiago (Ruta 40) Travel Pass - October 2025

Real Peru to Bolivia - October 2025

Rio de Janeiro to Buenos Aires (via Florianopolis & Iguazu) Travel Pass - October 2025

Real Bolivia to Brazil - October 2025

Page 2 of 241 Trips in Andes during October 2025 with 249 Reviews

Europe

Asia

South America

Africa

North America

Oceania

Polar

Food, wine, events and nightlife

Adventure and sport

Wildlife, landscapes and nature

Boat tours, water sports and marine wildlife

Sightseeing, attractions, culture and history

Air tours, road trips and transfers

Beach, romance, getaways and relaxation

Special interests and hobbies

All Andes Tours in October 2025

Page 2 of 241 Trips in Andes during October 2025 with 249 Reviews

Page 2 of 241 Trips in Andes during October 2025 with 249 Reviews