10 Best Andes Multiday Tours in May 2027

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Epic South America - May 2027

No booking fees

Best price guaranteed

Experience the full spectrum of South America on this epic 39-day adventure – the perfect way to forge lifelong connections. Follow in the footsteps of ancient people on the Inca Trail in Peru, drive past volcanoes, lakes, llamas and flamingos in the Atacama Desert and marvel at the might of Iguazu Falls. Spend nights on an estancia (farm) in Uruguay and at a homestay on Lake Titicaca, sample Argentinian barbecue in Buenos Aires and roam through the Amazon jungle. With like-minded travel companions and a local leader providing recommendations at every stop, this’ll be a South American expedition like no other.

Adventure

Tour Type

Small Group Tour

Accommodation

Camping, Home-stay, Hotel, Lodge

Age Range

18-35 yrs

Operated in

english

Destinations

Rio de Janeiro, Lima, Puno, Lake

Rio de Janeiro, Lima, Puno, Lake Titicaca, La Paz, Salar De Uyuni, Altiplano, San Pedro De Atacama, Puerto Maldonado, Salta, Buenos Aires, Montevideo, Estancia, Cusco, Iguazu Falls, Iguazu Falls, Paraty, Ilha Grande, Ollantaytambo, Inca Trail

Duration39 days

From

USD 7,175

USD 6,960

Saving

USD 215

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Bolivia To Peru: Lakes, Salt Flats & Machu Picchu - May 2027

22% OFF TODAY

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Bolivia to Peru: Lakes, Salt Flats & Machu Picchu - May 2027

No booking fees

Best price guaranteed

Combine two of South America’s must-see countries on a 25-day adventure through Bolivia and Peru. From inspiring geography, to cities rich in colonial history, and Indigenous culture, immerse yourself in these destinations and come home completely changed. Explore the highest capital city in the world, travel to the crest of the Andes, spend three days exploring the Uyuni Salt Flats, and conquer the mighty Inca Trail, soaking up the stunning views of majestic Machu Picchu. If you are looking for an authentic experience away from the tourist track, while still hitting the highlights, well, you've found it.

Explorer

Tour Type

Small Group Tour

Accommodation

Camping, Home-stay, Hotel, Lodge, Bungalow, Villa

Age Range

12-100 yrs

Operated in

english

Destinations

Lima, La Paz, Puno, Lake Titicac

Lima, La Paz, Puno, Lake Titicaca, Cusco, Ollantaytambo, Inca Trail, Sucre, Potosi, Uyuni, Salt Flats

22% OFF TODAY

Duration25 days

From

USD 4,249

USD 3,297

Saving

USD 952

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22% OFF TODAY

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Real Argentina to Brazil - May 2027

No booking fees

Best price guaranteed

Embark on a South American escapade from Buenos Aires to Rio de Janeiro on this 14-day adventure. Soak up the might of Argentina before crossing to the charming city of Colonia del Sacramento, then explore the lively Mercado del Puerto in Montevideo. Spend two nights getting to know the locals on an estancia (farm) in Uruguay, either chipping in with the chores or relaxing in the sun, then marvel at the majesty of Iguazu Falls. Finishing off in the paradise of Ilha Grande and the buzz of Rio de Janeiro, you’ll experience the many sides of South America.

Adventure

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

18-35 yrs

Operated in

english

Destinations

Buenos Aires, Rio de Janeiro, Pa

Buenos Aires, Rio de Janeiro, Paraty, Ilha Grande, Montevideo, Estancia, Iguazu Falls

22% OFF TODAY

Duration14 days

From

USD 2,895

USD 2,247

Saving

USD 648

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Sao Paulo, Rio de Janeiro & Iguazu Falls - May 2027

Trip customizable

Best price guaranteed

Embark on an unforgettable 9-day journey through Brazil’s most iconic destinations: São Paulo, Rio de Janeiro, and Iguazu Falls. Start your adventure in São Paulo, Brazil's vibrant financial hub and cultural capital, where the bustling streets are alive with diverse culinary delights, world-class museums, and eclectic neighborhoods. Next, head to Rio de Janeiro, a dazzling coastal city renowned for its stunning beaches—Copacabana and Ipanema—the awe-inspiring 38-meter-high Christ the Redeemer statue atop Corcovado Hill, and the panoramic views from Sugar Loaf Mountain, accessible via thrilling cable car rides. Your journey culminates at the breathtaking Iguazu Falls, a natural wonder straddling the border between Brazil and Argentina. Marvel at the sheer power and beauty of 275 individual waterfalls, with the tallest, the 80-meter Devil’s Throat, offering an unforgettable spectacle. Iguazu Falls is truly one of the seven natural wonders of the world and a must-visit on any South American itinerary. This tour promises a perfect blend of urban excitement, natural beauty, and cultural immersion, showcasing the very best of Brazil’s diverse landscapes and vibrant cities.

Rainforest and jungle visits

Tour Type

Independent Tour

Age Range

1-79 yrs

Operated in

english, spanish

Destinations

Iguazu Falls, Sao Paulo, Rio de

Iguazu Falls, Sao Paulo, Rio de Janeiro, Iguazu Falls National Park, Foz De Iguazú, Foz Do Iguacu, Puerto Iguazu

Duration9 days

From

USD 2,610

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Río de Janeiro and Iguazú Waterfalls - May 2027

Trip customizable

Best price guaranteed

Rio de Janeiro and Iguazu falls is a carefully crafted 7-day guided tour package that takes you from Rio de Janeiro in Brazil to Iguazu Falls in Argentina. Enjoy sunset walks along the famous beaches of Rio de Janeiro, visit the Sugar Loaf Mountain on a cable-car, and admire the majestic Iguazu Falls from both Argentina and Brazil. Accompanied by our expert guides, you will learn and explore all the hidden gems on a city sightseeing tour and stop for delicious food on the way. Enjoy unobstructed views of Guanabara Bay, Sugar Loaf and the Burle Marx gardens. This tour offers a great combination of nature and culture. Please see our itinerary for more details.

Rainforest and jungle visits

Tour Type

Independent Tour

Accommodation

Hotel

Age Range

1-79 yrs

Operated in

English

Destinations

Iguazu Falls, Rio de Janeiro, Pu

Iguazu Falls, Rio de Janeiro, Puerto Iguazu, Foz De Iguazú, Iguazu Falls

Duration7 days

From

USD 1,775

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Northern Argentina & Chile Tour - May 2027

Trip customizable

Best price guaranteed

Explore the vibrant cities of Salta and Cafayate, traverse the diverse landscapes of the Puna region and delve into the cultural wonders of Quebrada de Humahuaca with our 10-day partially guided Northern Argentina and Chile Tour. On this tour, you will have the chance to cross the majestic Andes and explore the arid expanse of the Atacama Desert in Chile, marvel at the famous multicolored hills, serene lagoons and surreal geological formations and discover the desert’s stark beauty and vast open spaces that offer a stark contrast to the lush valleys of Argentina. Please see our itinerary for more details.

ExplorerDeserts and canyons

Tour Type

Independent Tour

Age Range

1-79 yrs

Operated in

english, spanish

Destinations

Salta, Cafayate, Purmamarca, San

Salta, Cafayate, Purmamarca, San Pedro De Atacama, Calama, Moon Valley

Duration10 days

From

USD 2,700

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10% OFF TODAY

Essential South America featuring Chile, the Mendoza Wine Region & Buenos Aires - May 2027

No booking fees

Best price guaranteed

Experience the essence of two South American countries on a comprehensive journey from Santiago, Chile to Argentina’s wine country and vibrant Buenos Aires. Stroll through Santiago’s Central Market, picking up fresh ingredients to incorporate in a seafood lunch. Spend two nights in Mendoza, South America’s famous wine country. Discover the rhythm of Buenos Aires and learn to tango with the best. In the Pampas of Argentina, explore gaucho culture and spend a day on a traditional estancia. Encounter the history and culture of Chile and Argentina in capital cities and the sprawling countryside.

Cultural, religious and historic sites

Tour Type

Group Tour

Accommodation

Hotel

Age Range

1-99 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Mendoza

10% OFF TODAY

Duration10 days

From

USD 4,099

USD 3,699

Saving

USD 400

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Santiago to Buenos Aires: Volcanos, Valleys & the Lake District - May 2027

No booking fees

Best price guaranteed

Pack your bags and get ready to bounce through South America on this 12-day ride full of wild nature, epic nights, and laid-back lake vibes. Start in Santiago and hop an overnight bus to Pucón, where volcanoes, hot springs, and endless adventure await. Cruise through Chile’s dreamy Lake District with a chill stop in Puerto Varas, then cross into Argentina to explore the outdoorsy paradise of Bariloche. Hike, bike, or just soak it all in — your pace, your way. Wrap things up in buzzing Buenos Aires with tango, steak, and one last big night out. This is South America in full colour, and you’re living it large.

Explorer

Tour Type

Small Group Tour

Accommodation

Hostel, Hotel

Age Range

18-39 yrs

Operated in

english

Destinations

Buenos Aires, Santiago, Pucon, P

Buenos Aires, Santiago, Pucon, Puerto Varas, San Carlos de Bariloche

Duration12 days

From

USD 1,599

USD 1,551

Saving

USD 48

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Central and South American Adventure: From Costa Rica to Colombia - May 2027

No booking fees

Best price guaranteed

Phones charged and playlists queued — this 27-day journey is a full-on adventure through Central and South America that’s packed with wild nature, laid-back beach towns, and buzzing cities. Start in Costa Rica with the surfy chill of Puerto Viejo before heading into Panama’s hidden gems — think island time in Bocas del Toro, misty hikes in Boquete, and the crater village of Valle de Antón. Then go fully off-grid on the San Blas Islands, where Indigenous communities run the show and turquoise water meets white sand. After that, it’s Colombia time. Wander Cartagena’s colourful old town, trek through jungle trails to waterfalls in Minca, kick back in Santa Marta, and finish strong in Medellín with mountaintop views and a nightlife scene to match. From slow travel moments to fast-paced fun, this one’s got it all.

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Hostel, Hotel, Hut

Age Range

18-39 yrs

Operated in

english

Destinations

San Jose, Medellin, Valle De Ant

San Jose, Medellin, Valle De Antón, Panama City, San Blas Islands, Cartagena, Puerto Viejo de Talamanca, Minca, Palomino, Tayrona National Park, Santa Marta, Bocas Del Toro, Boquete

Duration27 days

From

USD 3,999

USD 3,879

Saving

USD 120

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Active Galápagos & Machu Picchu - May 2027

No booking fees

Best price guaranteed

Active travelers looking to combine the stunning wildlife of the Galápagos Islands with the deep history of Peru’s Inca Trail should explore this incredible 17-day adventure. Stay onshore while visiting lesser-visited islands and spending your days with playful sea lions, majestic manta rays, and the famous Galápagos tortoise. Then, head to Peru and take on the iconic 4-day Inca Trail trek to Machu Picchu, surrounded by mountainscapes, cloud forests, and jungle views. This is a journey that will inspire and impress at every turn.

Explorer

Tour Type

Small Group Tour

Accommodation

Guest House, Hotel, Camping

Age Range

12-100 yrs

Operated in

english

Destinations

Cusco, Quito, Lima, Ollantaytamb

Cusco, Quito, Lima, Ollantaytambo, Inca Trail, Isla Santa Cruz, Floreana Island, Isabela Island

Duration17 days

From

USD 5,499

USD 5,334

Saving

USD 165

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18% OFF TODAY

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Machu Picchu & Galapagos - May 2027

No booking fees

Best price guaranteed

Combine two of the great adventure destinations in one trip: Machu Picchu, one of the New Wonders of the World, and the wildlife-watching haven of the Galapagos Islands. Starting in Peru, we explore the Inca empire, first visiting Cuzco and the nearby ruins, before taking the train through mountains and cloud forest to the once-lost city of Machu Picchu – hiking a section of the Inca Trail if you wish. It’s then off to the Galapagos, exploring land and sea in search of sharks, giant tortoises, sea lions and more with an expert naturalist guide.

Cultural, religious and historic sites

Tour Type

Small Group Tour

Accommodation

Hotel

Age Range

16-99 yrs

Operated in

english

Destinations

Cusco, Quito, Floreana Island, I

Cusco, Quito, Floreana Island, Isla Santa Cruz, Ollantaytambo, Aguas Calientes, San Cristobal Island, Isla Lobos

18% OFF TODAY

Duration15 days

From

USD 7,498

USD 6,184

Saving

USD 1,314

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Ecuador & Peru Classic 10 Days - May 2027

Trip customizable

Best price guaranteed

Embark on a captivating 10-day journey through Ecuador and Peru. Start in Quito, exploring its historic sites and stunning viewpoints. Discover the majestic Cotopaxi National Park and the ancient Ingapirca Archaeological Complex. Experience the cultural richness of Cuenca and the vibrant city of Guayaquil. Then, fly to Cusco, where you'll delve into Inca history and visit the Sacred Valley's remarkable ruins. Conclude your adventure with an unforgettable tour of Machu Picchu, before exploring Lima’s historic center. This tour combines breathtaking landscapes, rich culture, and unforgettable experiences in two incredible countries. For more details, check out the itinerary section.

City sightseeing

Tour Type

Small Group Tour

Age Range

10-79 yrs

Operated in

english, spanish

Destinations

Cusco, Machu Picchu, Quito, Lima

Cusco, Machu Picchu, Quito, Lima, Cuenca, Guayaquil, Aguas Calientes, Sacred Valley, Cotopaxi National Park, Riobamba

Duration10 days

From

USD 2,950

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GalaPicchu Insiders 10 Days Tour - May 2027

Trip customizable

Best price guaranteed

Get ready for an unforgettable journey through Ecuador, the Galapagos Islands, and Peru. Over 10 days, you’ll explore breathtaking landscapes, encounter unique wildlife, and immerse yourself in rich cultural heritage. Your adventure begins in Quito, Ecuador, where colonial charm meets modern vibrancy. From there, you’ll fly to the Galapagos Islands, a natural wonderland teeming with wildlife. Kayak alongside sea lions, snorkel with hammerhead sharks, and hike volcanic trails. Next, travel to Peru, where you’ll uncover the mysteries of the Inca Empire. Explore Cusco’s ancient ruins, marvel at the Sacred Valley, and stand in awe of Machu Picchu, the Lost City of the Incas. Your journey concludes in Lima, where history and culture come alive in its vibrant streets.

SnorkelingCity sightseeing

Tour Type

Small Group Tour

Age Range

8-79 yrs

Operated in

english, spanish

Destinations

Cusco, Machu Picchu, Quito, Lima

Cusco, Machu Picchu, Quito, Lima, Guayaquil, Ollantaytambo, Pisac, Aguas Calientes, Isla Santa Cruz, San Cristobal Island, Bartolome Island

Duration10 days

From

USD 3,350

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Adventure in Iguazu - 2 nights - May 2027

Trip customizable

Best price guaranteed

This tour is a 2-night program to visit Iguazu Falls, one of the most incredible places in the world! The program includes a visit to two different national parks, one in Argentina and the other one in Brazil. The Argentinian Park offers up to 8 kilometres of trails to enjoy the falls in three different circuits: Upper circuit, Lower circuit and trail to the Devil´s Throat. We will also undertake some great adventure activities in the jungle, including riding a 4x4 truck, hiking and a boat navigation to enjoy the falls from the river. On the Brazilian side is a 1500-meter trail on which we can enjoy a wonderful panoramic view of the falls. The best part? The tour includes a helicopter flight to enjoy the falls from the sky! Are you ready?

Natural landmarks sightseeing

Tour Type

Group Tour

Accommodation

Hotel

Age Range

5-79 yrs

Operated in

english, spanish

Destinations

Iguazu Falls, Iguazu Falls

Duration3 days

From

USD 590

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All Andes Tours in May 2027

Page 4 of 350 Trips in Andes during May 2027 with 1,336 Reviews

Epic South America - May 2027

Bolivia to Peru: Lakes, Salt Flats & Machu Picchu - May 2027

Real Argentina to Brazil - May 2027

Sao Paulo, Rio de Janeiro & Iguazu Falls - May 2027

Río de Janeiro and Iguazú Waterfalls - May 2027

Northern Argentina & Chile Tour - May 2027

Essential South America featuring Chile, the Mendoza Wine Region & Buenos Aires - May 2027

Santiago to Buenos Aires: Volcanos, Valleys & the Lake District - May 2027

Central and South American Adventure: From Costa Rica to Colombia - May 2027

Active Galápagos & Machu Picchu - May 2027

Machu Picchu & Galapagos - May 2027

Ecuador & Peru Classic 10 Days - May 2027

GalaPicchu Insiders 10 Days Tour - May 2027

Adventure in Iguazu - 2 nights - May 2027

Page 4 of 350 Trips in Andes during May 2027 with 1,336 Reviews

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All Andes Tours in May 2027

Page 4 of 350 Trips in Andes during May 2027 with 1,336 Reviews

Page 4 of 350 Trips in Andes during May 2027 with 1,336 Reviews