Colombia in 6 Days: 2 Recommended 6-Day Itineraries to Colombia

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Colombia 6-day Itinerary Options
Whether it’s exploring Getsemaní, a neighborhood in Cartagena famous for its creative street art, or soaking in the Spanish-era vibes of Santa Fe de Antioquia, our top Colombia 6-day itinerary suggestions will help you choose the most striking destinations and memorable experiences.
Itinerary #1: Explore the Caribbean Coast

Overview | Activity | Overnight | |
Day 1 | Arrive in Cartagena and explore the ramparts of the city | Arrival | Cartagena |
Day 2 | Stroll along the streets of the Old City | Cultural tour | Cartagena |
Day 3 | Explore the bay in Bocagrande’s Castillo Grande district | Beach day | Cartagena |
Day 4 | Take a boat to Islas del Rosario | Boating | Islas del Rosario |
Day 5 | Relax on the beaches of Rosario | Beach day | Islas del Rosario |
Day 6 | End your trip in Cartagena | Departure |
Lose yourself in the atmospheric streets of Cartagena’s Old City, dig into a Colombian-style ceviche (typically made of the best catch of the day, like shellfish, shrimp, or oysters), and find out why Rosario Islands are on every tourist radar during your 6 days in Cartagena. After arriving in Cartagena, stroll along the city’s impressive walls that were built by the Spaniards to ward off the British Navy and pirates. The next day, continue exploring the Old City on foot, covering landmarks like the leafy Plaza de Bolívar and the Castillo de San Felipe, an impregnable fortress built by the Spaniards in the 17th century and expanded in the 18th century. On the third day, discover Cartagena’s vibrant bay area, Bocagrande, and the tapas bars of Getsemaní, a colorful neighborhood where graffiti has evolved into an art form. You can spend most of the second half of your Colombia 6-day itinerary plan enjoying the Caribbean vibe of the Rosario Islands. There’s a lot to do here, from kayaking and snorkeling in the clear waters amid corals to partying late into the night and lazing on the white sandy beaches. After this lovely extended beach detour, you may have time for another stroll in Cartagena before your 6-day Colombian vacation ends. Describe your ideal 6-day holiday for a customized trip to Colombia.
Itinerary #2: Everything in Medellin

Overview | Activity | Overnight | |
Day 1 | Arrive in Medellin | Arrival | Medellin |
Day 2 | Do a city tour of Medellin | Sightseeing | Medellin |
Day 3 | Visit the town of Guatape | Water sports | Medellin |
Day 4 | Discover the flower-growing area of Santa Elena | Nature | Medellin |
Day 5 | Visit the Hacienda Napoles theme park | Theme part | Medellin |
Day 6 | See the main attractions of Santa Fe de Antioquia | Departure |
Medellin is known as the ‘City of Eternal Spring’ not just for its year-long cool weather but also because it is part of a stunning flower-producing region. Discover these and other delightful aspects of Medellin during your 6 days in Colombia. Start by visiting Medellin’s Museo de Antioquia, which has a collection of paintings and sculptures by Fernando Botero, one of Colombia’s greatest artists, and the Museum of Modern Art, which has around 2,400 works by Colombian artists like Beatriz González, Santiago Cárdenas and Clemencia Echeverri. The next day, explore Guatape, a town strategically located beside a water reservoir. The Big Rock, or “El Peñol,” offers splendid views of the town. You can also try water sports like jet skiing and kayaking here. On the fourth day, visit a beautiful flower farm in Santa Elena, learn about the area’s silleteros (flower growers), and immerse yourself in the aromas of tens of thousands of flowers. Next day, enjoy the thrills and rides at Hacienda Nápoles’s theme park, which includes a water park and an exotic zoo. On the sixth and final day of your remarkable Medellin itinerary, visit Santa Fe de Antioquia, a town known for its beautifully preserved colonial architecture. Top sights include the Puente de Occidente, a 19th-century suspension bridge; the pleasant central square, Plaza Mayor; and the Cathedral Basilica, which has impressive religious artifacts.
Planning a 6-day Itinerary of Colombia?
Admire the intricately designed decorations on Guatape’s beautiful buildings, discover how the former estate of a notorious drug lord was converted into a popular recreational area, and soak in the sun and sand at the wonderful Rosario Islands in 6 days in Colombia. See our travel guide for more ideas on how long to spend in Colombia. Our travel experts in Colombia will prepare a personalized itinerary for you to make your dream Colombian vacation a reality.
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